• Title/Summary/Keyword: Base pair

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EXPLICIT EQUATIONS FOR MIRROR FAMILIES TO LOG CALABI-YAU SURFACES

  • Barrott, Lawrence Jack
    • Bulletin of the Korean Mathematical Society
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    • v.57 no.1
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    • pp.139-165
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    • 2020
  • Mirror symmetry for del Pezzo surfaces was studied in [3] where they suggested that the mirror should take the form of a Landau-Ginzburg model with a particular type of elliptic fibration. This argument came from symplectic considerations of the derived categories involved. This problem was then considered again but from an algebro-geometric perspective by Gross, Hacking and Keel in [8]. Their construction allows one to construct a formal mirror family to a pair (S, D) where S is a smooth rational projective surface and D a certain type of Weil divisor supporting an ample or anti-ample class. In the case where the self intersection matrix for D is not negative semi-definite it was shown in [8] that this family may be lifted to an algebraic family over an affine base. In this paper we perform this construction for all smooth del Pezzo surfaces of degree at least two and obtain explicit equations for the mirror families and present the mirror to dP2 as a double cover of ℙ2.

Reduction of Drag on a Two-Dimensional Model Vehicle Using Wake Disrupter (이차원 운송체 모형에서 후류 교란자를 이용한 항력 감소)

  • Lee, Dong-Kon;Choi, Jin;Jeon, Woo-Pyung;Kim, Jeong-Lae;Hahn, Seong-Hyeon;Choi, Hae-Cheon
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.652-657
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    • 2003
  • A wind-tunnel experiment is carried out to examine the applicability of a new passive device, wake disrupter, to flow over a model vehicle for drag reduction. The wake disrupter is a small-size rectangular body attached to a part of the trailing edge of the model vehicle, designed to perturb an essentially two-dimensional nature of wake. A pair of wake disrupter is mounted on the mid-span at the upper and lower trailing edges. From a parametric study about the size of wake disrupter, it is found that the optimum disrupter increases the base pressure by about 20%. Large eddy simulation is also conducted to confirm the experimental result, and shows that the wake is indeed disrupted by the present device.

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An Analytical Investigation on the Ratio of Angular Velocity in Spherical Involute Bevel Gearsets (구형 인볼류트 베벨기어쌍의 각속도비에 관한 해석적 연구)

  • Park, N.G.
    • Journal of the Korean Society for Precision Engineering
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    • v.12 no.5
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    • pp.40-45
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    • 1995
  • The kinematical relationship of bevel gearsets lies at the root of the gear design. As the demand on precision bevel gears is increased in the related industries, the kinematic analysis of a pair of sperical involute bevel gears needs to be exactly evaluated for the computer aided design. Pitch cone angles of bevel gearsets have been calculated under the assumption that the geared system is equivalent to a coned roller system without slipping. But this kinematical model involves some errors in the value of the ratio of angular velocity. In this paper, the ratio of the angular velocity is exactly derived, based on the perfect involute tooth surface. Four nonlinear equations representing the kinematical relationships are numerically solved to obtain the pitch and base cone angles. The ratios of angular volocities according to pressure and shaft angles are calculated and compared with those of the approximate gear model.

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One-Step Selection of Artificial Transcription Factors Using an In Vivo Screening System

  • Bae, Kwang-Hee;Kim, Jin-Soo
    • Molecules and Cells
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    • v.21 no.3
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    • pp.376-380
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    • 2006
  • Gene expression is regulated in large part at the level of transcription under the control of sequence-specific transcriptional regulatory proteins. Therefore, the ability to affect gene expression at will using sequencespecific artificial transcription factors would provide researchers with a powerful tool for biotechnology research and drug discovery. Previously, we isolated 56 novel sequence-specific DNA-binding domains from the human genome by in vivo selection. We hypothesized that these domains might be more useful for regulating gene expression in higher eukaryotic cells than those selected in vitro using phage display. However, an unpredictable factor, termed the "context effect", is associated with the construction of novel zinc finger transcription factors--- DNA-binding proteins that bind specifically to 9-base pair target sequences. In this study, we directly selected active artificial zinc finger proteins from a zinc finger protein library. Direct in vivo selection of constituents of a zinc finger protein library may be an efficient method for isolating multi-finger DNA binding proteins while avoiding the context effect.

A Study on the Optimal Design, Modeling and Control of the Multi d.o.f Precision Positioning System Using Magnetic Levitation Actuating Principle (자기 부상 방식 구동원리를 이용한 다자유도 정밀 위치 시스템의 최적 설계, 모델링 및 제어에 관한 연구)

  • Jeong, Gwang-Seok;Baek, Yun-Su
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.25 no.5
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    • pp.779-787
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    • 2001
  • The multi degree of freedom system using magnetic levitation has been implemented successfully. Differently from another noncontact systems, the developed system was focused on the maximization of the system stiffness under the constraint of a limited input. The variation of a relative adopting point between the magnetic pair, its location on the fixed base, and the selection of optimal specifications for the main active magnetic elements give us another chance to realize the increased robustness against external disturbances with the less control inputs. In this paper, the overall development procedures are given including the optimal design, the dynamic modeling, the various control tests, and the main issues to be solved.

ANTIMUTAGENIC EFFECT OF KOCHUJANG (KOREAN RED PEPPER SOYBEAN PASTE) AND KOCHUJANG INGREDIENTS IN THE AMES TEST

  • Jung, Keun-Ok;Kim, So-Ja;Yoon, Suk-Kwon;Park, Kun-Young
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.97-97
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    • 2001
  • The antimutagenicities of methanol extracts from traditional and commercial kochujang (Korean Red Pepper Soybean Paste) and their ingredients were evaluated in Salmonella/mammalian microsome assay system. The traditional kochujang showed higher antimutagenic effects than the commercial one against Ν-methyl-Ν'-nitro-Ν-nitrosoguanidine (MNNG) in the Salmonella typhimurium TA100, a base-pair substituted mutant strain.(omitted)

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Isolation of the Threonine Dehydratase Gene from a Tylosin-Producing Strain of Streptomyces fradiae

  • Lee, Sang Hee;Kye Joon Lee
    • Journal of Microbiology and Biotechnology
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    • v.5 no.5
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    • pp.305-308
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    • 1995
  • From the plasmid library made from Sstl and San-digested genomic DNA of Streptomyces fradiae NRRL 2702, four positive clones were selected using an oligodeoxynucleotide probe from the N-terminal amino acid sequence of purified threonine dehydratase. The cloned gene for threonine dehydratase was a 2.0 kilo-base pair DNA fragment. The deduced amino acid sequence of PCR product (PCR245) was matched to that of the N-terminal part of threonine dehydratase from S. fradiae and this showed a high similarity to the threonine dehydratases of other organisms. This indicated that amino acid sequences of threonine dehydratases were highly conserved and the polypeptide product of the PCR245 was likely to be involved in the deamination of threonine.

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A Forecasting System for Lung Cancer Sensitivities Using SNP Data

  • Ryoo, Myung-Chun;Kim, Sang-Jin;Park, Chang-Hyeon
    • 한국정보컨버전스학회:학술대회논문집
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    • 2008.06a
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    • pp.191-194
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    • 2008
  • SNP(Single Nucleotide Polymorphism) refers to the difference in a base pair existed in DNAs of individuals. Each of it appears per 1,000 bases in human genome and it enables each gene to defer in junctions, interacts with each other to make different shapes of humans, and produces different disease sensitivities. In this paper, we propose a system to forecast lung cancer sensitivities using SNP data related with the lung cancer. A lung cancer sensitivity forecasting model is also constructed through analysis of genetic and non-genetic factors for squamous cell carcinomas, adeno carcinomas, and small cell carcinomas that may frequently appear in Korean. The proposed system with the model gives the probabilities of the onset of lung cancers in the experimental subjects.

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A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of ENCODE/Broad ChromHMM Annotations: A Computational Perspective

  • Park, Hyun-Seok
    • Genomics & Informatics
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    • v.16 no.3
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    • pp.65-70
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    • 2018
  • The non-coding DNA in eukaryotic genomes encodes a language which programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this short report was to determine the impact of primary DNA sequence on the epigenomic landscape across 200-base pair genomic units by integrating nine publicly available ChromHMM Browser Extensible Data files of the Encyclopedia of DNA Elements (ENCODE) project. The nucleotide frequency profiles of nine chromatin annotations with the units of 200 bp were analyzed and integrative Markov chains were built to detect the Markov properties of the DNA sequences in some of the active chromatin states of different ChromHMM regions. Our aim was to identify the possible relationship between DNA sequences and the newly built chromatin states based on the integrated ChromHMM datasets of different cells and tissue types.

Modeling of Blend Surfaces by Bezier Surface Patches (비지어곡면에 의한 블렌드곡면의 모델링)

  • 주상윤
    • Korean Journal of Computational Design and Engineering
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    • v.2 no.2
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    • pp.122-129
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    • 1997
  • Ball rolling blending is a popular technique for blending between parametric surfaces. The ball rolling blend surface is conceptually a trajectory of a ball rolling between two base sufaces. It is constructed by sweeping a circular arc along a ball contact curve pair. Since a ball rolling blend surfaces does not have a polynomial form like a Bezier surface patch, it is impossible to apply this method directly to a commercial CAD/CAM system. In this paper an algorithm is developed to approximate a ball rolling blend surface into Bezier surface patches. Least square method is applied to obtain proper Bezier surface patches under a given tolerance. The Bezier surface patches have degree three or more and guarantee VC1-continuity.

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