• Title/Summary/Keyword: Barrier factor

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Effect of thermal conductivity degradation on the behavior of high burnup $UO_2$ fuel

  • Lee, Byung-Ho;Koo, Yang-Hyun;Sohn, Dong-Seong
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05c
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    • pp.265-270
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    • 1996
  • The temperature distribution in the pellet was obtained from beginning the general heat conduction equation. The thermal conductivity of pellet used the SIMFUEL data that made clear the effect of burnup on the thermal conductivity degradation. Since the pellet rim acts as the thermal barrier to heat flow. the pellet was subdivided into several rings in which the outer ring was adjusted to play almost the same role as the rim. The local burup in each ring except the outer ring was calculated from the power depression factor based on FASER results. whereas the rim burnup at the outer ring was achieved by the pellet averaged burnup based on the empirical relation. The rim changed to the equivalent Xe film so the predicted temperature shooed the thermal jump across the rim. The observed temperature profiles depended on linear heat generation rate. fuel burnup. and power depression factor. The thermal conductivity degradation modelling can be applied to the fuel performance code to high burnup fuel,

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Novel host and electron blocking materials for efficient and long lifetime phosphorescent OLEDs

  • Vestweber, Horst;Gerhard, Anja;Kaiser, Joachim;Heil, Holger;Kroeber, Jonas;Pflumm, Christof;Stoessel, Philipp;Joosten, Dominik;Buesing, Arne;Fortte, Rocco;Parham, Amir;Boehm, Edgar
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.925-927
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    • 2008
  • In order to improve the performance in green phosphorescent OLED devices, Merck has developed novel host and electron blocking materials. The newly developed host materials improve the device lifetime by a factor of 3. The newly developed electron blocking materials having not only electron but also exciton barrier properties increase the efficiency of the device by a factor of 1.4. Comparable results were achieved in phosphorescent red systems with further host materials.

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A New Scaling Theory for the Effective Conducting Path Effect of Dual Material Surrounding Gate Nanoscale MOSFETs

  • Balamurugan, N.B.;Sankaranarayanan, K.;Suguna, M.
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.8 no.1
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    • pp.92-97
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    • 2008
  • In this Paper, we present a scaling theory for dual material surrounding gate (DMSGTs) MOSFETs, which gives a guidance for the device design and maintaining a precise subthreshold factor for given device parameters. By studying the subthreshold conducting phenomenon of DMSGTs, the effective conductive path effect (ECPE) is employed to acquire the natural length to guide the design. With ECPE, the minimum channel potential is used to monitor the subthreshold behavior. The effect of ECPE on scaling factor significantly improves the subthreshold swing compared to conventional scaling rule. This proposed model offers the basic designing guidance for dual material surrounding gate MOSFETs.

Brain metastasis in human epidermal growth factor receptor 2-positive breast cancer: from biology to treatment

  • Koo, Taeryool;Kim, In Ah
    • Radiation Oncology Journal
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    • v.34 no.1
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    • pp.1-9
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    • 2016
  • Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved. Nonetheless, the incidence of brain metastasis does not be improved, rather seems to be increased in HER2-positive breast cancer. The mainstay treatment for brain metastases is radiotherapy. According to the number of metastatic lesions and performance status of patients, radiosurgery or whole brain radiotherapy can be performed. The concurrent use of a radiosensitizer further improves intracranial control. Due to its large molecular weight, trastuzumab has a limited ability to cross the blood-brain barrier. However, small tyrosine kinase inhibitors such as lapatinib, has been noted to be a promising agent that can be used as a radiosensitizer to affect HER2-positive breast cancer. This review will outline general management of brain metastases and will focus on preclinical findings regarding the radiosensitizing effect of small molecule HER2 targeting agents.

Wet-work Exposure: A Main Risk Factor for Occupational Hand Dermatitis

  • Behroozy, Ali;Keegel, Tessa G.
    • Safety and Health at Work
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    • v.5 no.4
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    • pp.175-180
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    • 2014
  • Wet-work can be defined as activities where workers have to immerse their hands in liquids for >2 hours per shift, or wear waterproof (occlusive) gloves for a corresponding amount of time, or wash their hands >20 times per shift. This review considers the recent literature on wet-work exposure, and examines wet-work as a main risk factor for developing irritant contact dermatitis of the hands. The aim of this paper is to provide a detailed description of wet-work exposure among specific occupational groups who extensively deal with water and other liquids in their occupations. Furthermore, it highlights the extent and importance of the subsequent adverse health effects caused by exposure to wet-work.

Innovative Method to Expand a Degree of Freedom of Observation in the Depth Direction without Losses of the Horizontal Number of Views in Autostereoscopic Multi-Views 3D Display System (시차장벽식 무안경 다시점 입체디스플레이 시스템에서 수평방향의 시점 수 저하 없이 깊이방향의 자유도를 증가시키기 위한 혁신적 방법)

  • Lee, Kwang-Hoon;Park, Min-Chul
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38C no.10
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    • pp.903-910
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    • 2013
  • An autostereoscopic multi-view 3D display system has the narrower degrees of freedom in the observational directions, such as the horizontal and perpendicular directions to the display plane, than the glasses-on type of 3D display. In this paper, we propose an innovative method to expand the width of the viewing zone formed in the depth direction while maintaining the number of views in the horizontal direction by using a triple segmented-slanted parallax barrier (TS-SPB) in the glasses-off type of 3D display. The validity of the proposal was verified by an optical simulation based on an environment similar to an actual case. The maximum number of views that can be displayed in the horizontal direction is 2n, and the width of the viewing zone with depth increased up to a factor of 3.36 compared to the existing one-layered parallax barrier system.

Defects and Electrical Properties of ZnO-Bi2O3-Mn3O4-Co3O4 Varistor (ZnO-Bi2O3-Mn3O4-Co3O4 바리스터의 결함과 전기적 특성)

  • Hong, Youn-Woo;Lee, Young-Jin;Kim, Sei-Ki;Kim, Jin-Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.12
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    • pp.961-968
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    • 2012
  • In this study, we have investigated the effects of Mn and Co co-doping on defects, J-E curves and grain boundary characteristics of ZnO-$Bi_2O_3$ (ZB) varistor. Admittance spectra and dielectric functions show two bulk defects of $Zn_i^{{\cdot}{\cdot}}$ (0.17~0.18 eV) and $V_o^{\cdot}$ (0.30~0.33 eV). From J-E characteristics the nonlinear coefficient (${\alpha}$) and resistivity (${\rho}_{gb}$) of pre-breakdown region decreased as 30 to 24 and 5.1 to 0.08 $G{\Omega}cm$ with sintering temperature, respectively. The double Schottky barrier of grain boundaries in ZB(MCo) ($ZnO-Bi_2O_3-Mn_3O_4-Co_3O_4$) could be electrochemically single type. However, its thermal stability was slightly disturbed by ambient oxygen because the apparent activation energy of grain boundaries was changed from 0.64 eV at lower temperature to 1.06 eV at higher temperature. It was revealed that a co-doping of Mn and Co in ZB reduced the heterogeneity of the barrier in grain boundaries and stabilized the barrier against an ambient temperature (${\alpha}$-factor= 0.136).

Enhancement of OH Radical Generation of Dielectric Barrier Discharge Plasma Gas Using Air-automizing Nozzle (이류체 노즐을 이용한 유전체장벽방전 플라즈마 가스의 OH 라디칼 생성 향상)

  • Park, Young-Seek
    • Journal of Environmental Science International
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    • v.27 no.8
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    • pp.621-629
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    • 2018
  • Many chemically active species such as ${\cdot}H$, ${\cdot}OH$, $O_3$, $H_2O_2$, hydrated $e^-$, as well as ultraviolet rays, are produced by Dielectric Barrier Discharge (DBD) plasma in water and are widely use to remove non-biodegradable materials and deactivate microorganisms. As the plasma gas containing chemically active species that is generated from the plasma reaction has a short lifetime and low solubility in water, increasing the dissolution rate of this gas is an important challenge. To this end, the plasma gas and water within reactor were mixed using the air-automizing nozzle, and then, water-gas mixture was injected into water. The dissolving effect of plasma gas was indirectly confirmed by measuring the RNO (N-Dimethyl-4-nitrosoaniline, indicator of the formation of OH radical) solution. The plasma system consisted of an oxygen generator, a high-voltage power supply, a plasma generator and a liquid-gas mixing reactor. Experiments were conducted to examine the effects of location of air-automizing nozzle, flow rate of plasma gas, water circulation rate, and high-voltage on RNO degradation. The experimental results showed that the RNO removal efficiency of the air-automizing nozzle is 29.8% higher than the conventional diffuser. The nozzle position from water surface was not considered to be a major factor in the design and operation of the plasma reactor. The plasma gas flow rate and water circulation rate with the highest RNO removal rate were 3.5 L/min and 1.5 L/min, respectively. The ratio of the plasma gas flow rate to the water circulation rate for obtaining an RNO removal rate of over 95% was 1.67 ~ 4.00.

Selection of Potential Virulence Factors Contributing to Streptococcus suis Serotype 2 Penetration into the Blood-Brain Barrier in an In Vitro Co-Culture Model

  • Liu, Hongtao;Zhu, Seng;Sun, Yingying;Li, Na;Gu, Jingmin;Sun, Changjiang;Feng, Xin;Han, Wenyu;Jiang, Jianxia;Lei, Liancheng
    • Journal of Microbiology and Biotechnology
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    • v.27 no.1
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    • pp.161-170
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    • 2017
  • Meningitis caused by Streptococcus suis serotype 2 (S. suis 2) is a great threat to the pig industry and human health. Virulence factors associated with the pathogenesis of meningitis have yet to be clearly defined, even though many potential S. suis 2 virulence factors have been identified. This greatly hinders the progress of S. suis 2 meningitis pathogenesis research. In this study, a co-culture blood-brain barrier (BBB) model was established using primary porcine brain microvascular endothelial cells and astrocytes, and the whole genome library of S. suis 2 was constructed using phage display technology. Finally, a total of 14 potential virulence factors contributing to S. suis 2 adherence to and invasion of the BBB were selected by analyzing the interactions between the phage library and the co-culture model. Twelve of these factors have not been previously reported in meningitis-related research. The data provide valuable insight into the pathogenesis of S. suis 2 meningitis and potential targets for the development of drug therapies.

Noise Reduction Method for Environment Friendly Housing Estate (신도시 친환경 주거단지조성을 위한 소음저감 대책방안)

  • 김흥식;주문기;주시웅
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.05a
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    • pp.535-541
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    • 2004
  • For housing estate of a new administrative capital city, Noise reduction method is a important design factor. As measuring a noise level of traffic noise according to separation from road, it can be created a quite housing estate. Analyzing of merits and demerits in sound barrier walls and tunnels can be proposed environment friendly soundproofing facilities. Number of measurement was performed to know what kind of layout of housing estate is good for noise reduction. Through this measurement, ㄷ shaped layout or parallel layout has the advantage of sound insulation rather than right angled layout. In this case (ㄷ shaped layout or parallel layout) buildings neighboring to the road should be designed to insulate sound. Evergreen trees should be planted between housing estate and road more than 30m (at least 7~8m) in order to reduce noise and have masking effects. If broad-leaved trees are planted more than 30m, approximately 10dB noise is reduced and 2~4dB if 7~8m. Roads in the estate should be designed considering pedestrians first, and special roads for moving and ambulance should be designed as skew road, if possible. The result shows that 15$^{\circ}$-sloped‘S’road reduces 1~2dB noise and 30$^{\circ}$-sloped road reduces 4~7dB. If noise barrier is inevitably installed, it should be designed to go well wit neighboring environment so as to install Environment Friendly Noise Barrier using materials and trees including wood and soil. Through this study the results are used to guideline for construction of environment friendly housing estate

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