• Journal of Korean Medicine Rehabilitation
• /
• v.20 no.2
• /
• pp.35-50
• /
• 2010

Objectives : In order to investigate the effects of So-yangin Biman-bang(here in after referred to BM) on the obese gene and obese inhibitory, C57BL/6 mice were distinctively induced by high fat diet. Methods : C57BL/6 mice were divided into four groups(normal, high fat diet with control, high fat diet with Reductil(here in after referred to RDT), high fat diet with BM extract) and have been fed for 8 weeks. Through observing the process, the weight change of the adipocytes in body and liver, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, glucose, leptin change in the serum, the expression of ${\beta}3AR$ and leptin gene in 3T3-L1 cell and primary adipocyte cell. Results : The following results have been found in this study. 1. Losing weight have significantly been shown. 2. The weight change of the body adipocyte and liver have been decreased but no significance has been found. 3. With close observation on the change of blood, HDL-cholesterol has positively been increased in numbers but the level of glucose, LDL-cholesterol, triglyceride have distinctively been decreased. 4. The manifestation of ${\beta}3AR$ in 3T3-L1 cell and primary adipocyte cell have shown a definite increase in numbers but the manifestation of leptin has shown certain decrease in its amount. Conclusions : As results of this, So-yangin Biman-bang is thought to be effective in metabolic syndrom and lipid metabolism disorder that can possibly be occurred by obesity control and treatment. The clinical research will be needed in order to apply to So-yangin constitution in the future.

• ICROS
• /
• v.12 no.4
• /
• pp.21-32
• /
• 2006

• The Journal of Korean Medicine
• /
• v.31 no.1
• /
• pp.30-46
• /
• 2010

Objectives: This study was performed to investigate the anti-obesity effects of Gambi-bang 4 (GBB4) on obesity-induced mice. Methods: C57BL/6 mice were divided into four groups (normal, high fat diet with control, high fat diet with Reductil, high fat diet with GBB4 extract) and fed for 8 weeks. We observed body weight change, the weight change of the adipocytes in body, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides, serum leptin level, expression of ${\beta}3AR$ and leptin genes in 3T3-L1 adipocytes and adipose tissue, and histological changes of adipose tissue and liver cells. Results: 1. Compared with the control group, the GBB4 group was significantly lower in body weight, weight of adipocytes, and amount of glucose. 2. The GBB4 group was significantly lower in the amount of total cholesterol, LDL-cholesterol and triglycerides, and HDL-cholesterol compared with the control. 3. Compared with the control group, the GBB4 group was significantly lower in the amount of serum leptin. 4. The GBB4 group was significantly higher in the revelation of ${\beta}3AR$ and leptin in 3T3-L1 adipocytes and primary adipose cells compared with the control. 5. Compared with the control group, the GBB4 group was smaller in the size of adipocytes in adipose tissue and the adipose vacuoles in liver tissue were decreased. Conclusions: These results suggested that GBB4 has inhibitory effects on obesity. GBB4 might be applied in treatment of obesity, so further studies analyzing its effects are needed.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.64 no.9
• /
• pp.1380-1384
• /
• 2015

The DC motor has the strong characteristics in the speed response, the system parameter variations and the external influence and is used as the speed controller with its good starting torque in the distributing industry. However development of the Microprocessor which is for high speed switching program can make better control system. This paper introduce to design of the high-effective DC motor controller that is using Software Bang-Bang Program of Fuzzy algorithm and to verify a PI controller and a Fuzzy controller.

• Proceedings of the KIEE Conference
• /
• 1996.07b
• /
• pp.1031-1033
• /
• 1996

Now is an automation age. Therefore it is required that machine can do work which was done by men. Artificial Neural Network was developed by the necessity of this purpose. This paper shows a Predictive Control with a Neural Network. The Neural Network learns an Inverted Pendulum in various situations. Then, it has a power to predict the next state after accept the current state. And the Neural Network directs the Bang-Bang Controller to give input to a plant. It seems like that a human expert looks the state of a plant and then controls the plant. It is used a Feedforward Neural Network and shown control state according to the learning. We could get a satisfactory results after complete learning.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.10 no.6 s.52
• /
• pp.93-102
• /
• 2006

Control input's saturation of active control devices for large structures under large external disturbances are often occurred. It is more difficult to obtain the exact values of mass and stiffness as structures are higher. The modelling errors between mathematical models and real structures must be also included as parameter uncertainties. Therefore, in active vibration control of civil engineering structures like buildings and bridges, the robust saturation controller design method considering both control input's saturation and parameter uncertainties of system is needed. In this paper, stabilities of linear optimal controller LQR, modified bang-bang controller, saturated sliding mode controller, and robust saturation controller among various controllers which have been studied and applied to active vibration control of buildings are investigated. Especially, unstable phenomena of the LQR, the modified bang-bang controller and the saturated sliding mode controller when the control input is saturated or parameter uncertainties exist are presented to show the necessity of the robust saturation controller. The robust stability of the robust saturation controller are shown through a numerical example of a 2DOF linear vibrating system and an experimental test of the two-story structure with an active mass damper (AMD).

• Journal of Navigation and Port Research
• /
• v.42 no.3
• /
• pp.237-244
• /
• 2018

When underwater rubble leveling work is carried out by a robot, real-time information on the topography around the robot is required for remote control. If the topographical information with respect to the current position of the robot is displayed as a 3D graphic image, it allows the operator to plan the working schedules and to avoid accidents like rollovers. Up until now, the topographical recognition was conducted by multi-beam sonars, which were only used to assess the quality before and after the work and could not be used to provide real-time information for remote control. This research measures the force delivered to the bucket which presses the mound to determine whether contact is made or not, and the contact position is calculated by reading the cylinder length. A variable bang-bang control algorithm is applied to control the heavy robot arms for the positioning of the bucket. The proposed method allows operators to easily recognize the terrain and intuitively plan the working schedules by showing relatively 3-D gratifications with respect to the robot body. In addition, the operating patterns of a skilled operator are programmed for raking, pushing, moving, and measuring so that they are automatically applied to the underwater rubble leveling work of the robot.

• Journal of Haehwa Medicine
• /
• v.20 no.1
• /
• pp.91-104
• /
• 2011

Background : Although chronic non-bacterial prostatitis is increasing, it is hard to treat effectively. In western medicine, antimicrobials drug, ${\alpha}$-adreno-ceptor antagonists, anti-inflammatory drugs, tricyclic antidepressants and anticholinergic agents are used commonly, but chronic prostatitis/chronic pelvic pain syndromes is confusing and frustrating for urologist. IDS(Indongsoyeom-bang) is used in treatment of chronic prostatitis/chronic pelvic pain syndromes. And it is reported that GLS(Gleditsiae spina) and TOF(Toosendan fructus) components of IDS have significant effect on protection of the glandular epithelial cells. Objective : In this study was conducted to investigate the therapeutic effects and action machanism of IDS in the rat model of non-bacterial prostatitis induced by castration and testosterone treatment. Methods : We observed six experimental objects of normal group, control group, testosterone group, and IDS 50 mg/kg, 200mg/kg, 400mg/kg group. Rats were treated with 17 ${\beta}$-estradiol after castration for induction of experimental non-bacterial prostatitis, which is similar to human chronic prostatitis in histophatological profiles. IDS and testosterone were administered as an experimental specimen and a positive control, respectively. The prostates were evaluated by histological parameters including the epithelial score and epithelio-stromal ratio for glandular damage. Also, the prostates were observed by Hematological alterations of WBC, RBC, hemoglobin and platelet. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with IDS-50 showed a diminished range of the tissue damage. Epithelial score was improved in IDS than that of the control. The epithelio-stromal ratio was lower in IDS when compared to that of the control. Also, the examination of bloods were not observed hematological change. Conclusion : These finding suggests that IDS may protects the glandular epithelial cells. We concluded that IDS could be a useful remedy agent for treating chronic non-bacterial prostatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.24 no.2
• /
• pp.16-27
• /
• 2011

Objective : To investigate the effects of Pyeongwi-san-gamibang on atopic dermatitis, this study measured TEWL(transepidermal water loss), observed scratching behaviors and checked levels of Total IgE, IL-4, IFN-${\gamma}$ and conducted skin biopsy on NC/Nga mice with atopic dermatitis. Methods : NC/Nga mice were challenged with DNCB during 5 weeks to develop atopic dermatitis-like skin lesions. The NC/Nga mice with atopic dermatitis were divided into three groups of control group, PW-d, PW-e group. Once a day for 22 days, Pyeongwi-san-GamiBang extract with water was administered for the PW-d group and the extract with 80% ethanol was administered for PW-e group compared with saline solution for control group. During drug administration, sensitization by DNCB had lasted for three times per week. Results : 1. TEWL had no statistical difference among 3 groups. 2. The scratching behaviors had no statistical difference among 3 groups. 3. The levels of Total IgE in PW-d, PW-e group had a statistically significantly higher than that of the control group although difference between the control group and the PW-d, PW-e group were similar. 4. The level of IL-4 had no statistical difference among 3 groups. 5. The level of IFN-${\gamma}$ had no statistical difference among 3 groups. 6. As the observation of toluidine blue stained lesion, both PW-d and PW-e group had lower level of histamine releasement compared with the control group. Conclusion : Result based on these experiments, Pyeongwi-san-GamiBang on atopic dermatitis-like skin inflammation in NC/Nga mice is not effective. But, as the study showed significantly individual differece, we need to repeat these study after supplementing the object number and modified indicator of clinical severity.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.19 no.3
• /
• pp.505-514
• /
• 1994

Koreasat spacecraft requires accurate and reliable attitude control to provide beam pointing for tenyear long communication and direction broadcasting services. This paper describes the detailed design and performance of an on-orbit normal mode attitude control subsystem for the spacecraft. Koreasat used a momentum wheel which has nominal momentum 475in-1b sec(547.6cm-kg sec) aligned with the pitch axis to control pitch attitude and provide gyroscopic stiffness in roll/yaw plane and used a 300 atm magnetic torquer to control the roll and yaw attitudes. An Earth Sensor Assembly (ESA) is used to provide pitch and roll information for the on-board micropocessor. The roll/yaw control used bang-off-bang control and while pitch axis control used proportional and integral control law. Control system errors during the operational normal mode are 0.03 deg, 0.1 deg and 0.01 deg in roll, yaw and pitch axes, respectively. Current attitude control system provides adequate control performances to capture initial attitude errors and spacecraft nutation.