• Natural Product Sciences
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• v.16 no.4
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• pp.245-250
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• 2010

Pulmonary pathogenesis in lupus is characterized by interstitial inflammation and vasculitis in lungs. We investigated whether bamboo culm extract (BC) attenuates pulmonary inflammation and lung injury in pristane-induced lupus mice. The pristane-induced lupus mice and healthy mice were administrated with BC 0.5 ml/kg or PBS orally once a day for 14 days. Our results demonstrated that BC significantly attenuated levels of bronchoalveolar lavage (BAL) IL-6, IL-10, IFN-$\gamma$, $PGE_2$ and VEGF, and pulmonary vascular permeability in pristane-induced lupus mice. Therefore, these findings suggest that BC may inhibit development of pulmonary inflammation and lung injury in lupus.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.9
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• pp.1265-1272
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• 2016

The objective of this study was to investigate the antioxidative components and anti-oralmicrobial effect of bamboo (Phyllostachys nigra var. henonis Stapf) leaves. The moisture, crude protein, crude fat, crude ash, and carbohydrate contents were 6.30%, 5.10%, 1.73%, 10.61%, and 76.26%, respectively. Vitamin C content was higher than Vitamin A and E contents. Among organic acids, citric acid content was the most abundant organic acid, followed by succinic acid, acetic acid, malic acid, and formic acid. Total polyphenol and flavonoid contents were 21.66 mg/g and 42.78 mg/g, respectively. Minimum inhibitory concentrations (MICs) of extracts of bamboo leaves for Streptococcus mutans and Streptococcus sobrinus were determined to be 0.04% and 0.16%, respectively. MICs of extracts of bamboo leaves for Porphyromonas gingivalis and Prevotella intermedia were determined to be 0.02%. Extract of bamboo leaves had strong antimicrobial activity against S. mutans, S. sobrinus, P. gingivalis, and P. intermedia at a concentration of 0.32%. At this concentration, extract of bamboo leaves inhibited growth of these pathogenic bacteria up to 60 h. The results of the present study demonstrate the antimicrobial effects of bamboo leaves ethanol extract against oral pathogenic bacteria, suggesting that bamboo leaves could be an effective natural agent for oral hygiene.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.3
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• pp.575-580
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• 2006

This Study was designed to investigate the effects of Mixture of Bambusae Caulis in Liquamen and Bamboo Extract on the change of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal and cerebral ischemic rats. Experimental materials were as follows ; BE- 1 was Bamboo Extract (BE) extracted with 70% ethyl alcohol, BE-11 was BE extracted with distilled water at $121^{\circ}C$ for 30 min, BE-111 was BE extracted with distilled water at $121^{\circ}C$ for 3 hrs, MLC was mixture of Bambusae Caulis in Liquamen (BCL) and BE-111 mixed at the ratio of 1 to 100 (MLC100), 1 to 50 (MLC50), 1 to 20 (MLC20), 1 to 10 (MLC10), 1 to 5 (MLC5). The results were as follows , The Changes of BE- 1 on the rCBF and MABP in normal rats were not showed, BE- 11 significantly decreased rCBF in a dose-dependent manner Dut increased MABP in a dose-dependent manner. BE-111 increased rCBF in a dose-dependent manner, MLC significantly increased rCBF in a dose-dependent manner and increased MABP in a dose-dependent manner. rCBF was significantly and stably increased by MLC5 (1 mg/kg, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. As results above ; The present author thought that BE- 111 and MLC increased rCBF by dilating pial arterial diameter.

• Journal of the Korea Convergence Society
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• v.13 no.4
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• pp.653-657
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• 2022

Oral disease causes a significant health and economic burden worldwide, significantly reducing people's quality of life. Dental caries, a representative oral disease, is caused by S. mutans. Oral pathogenic microorganisms contain lipopolysaccharide (LPS), which can cause an immune response and cause various oral diseases. The purpose of this study was to investigate the antioxidant and antibacterial effects of bamboo leaf extract (BLE) to control oral diseases. THP-1, oral fibroblasts, and S mutans culture medium were treated with bamboo leaf extract at different concentrations of 0-8% to conduct the experiment.. As a result, the antioxidant effect according to the BLE concentration was confirmed in mononuclear cell lines and oral fibroblasts. In addition, the antibacterial effect of S. mutans according to the BLE concentration was demonstrated. Therefore, BLE can be used for the prevention or treatment of oral diseases.

• Textile Coloration and Finishing
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• v.21 no.6
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• pp.29-38
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• 2009

Natural dyes seem to be more profitable on human and environment, and recently they could be considered as a better alternative to synthesized dyes. The aim of the current work was to investigate the dyeing property and antimicrobial activity of commercial cotton fabrics dyed with kumazasa (usually called in japan) which is known as conventional japan bamboo leaves. Actually, the dyeability and antimicrobial property of dyed fabric with natural mordant/dyeing was compared with synthetic mordant/dye process. The results of this study obtained are as follows. The apparently colour of kumazasa leaves extract dyed fabrics showed with light green or slightly yellow-green. In colorfastness to washing, ${\Delta}E$ and K/S values of dyed fabrics with natural chitosan as mordant used was shown to be more excellent results, than was synthetic mordant used. However, the decrease rate was recorded nearly 50% when washing repeated 20 cycles. In result of antimicrobial effect for bacteria, the dyed fabrics didn't show the significant antimicrobial activity to the both dyed with and without mordant. Results of this investigation considered that low-cost, natural, bio-mordant are relatively effective in natural coloration.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.8
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• pp.1279-1285
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• 2004

To evaluate the antimutagenic effect and hepato protective of bamboo trees and bamboo byproduct, hot-water extracts from four kinds of bamboo [wang-dae (Phyllostachys bambusoides S. et Z.), som-dae (Phyllostachys nigra var. henonis), maengjong-juk (Phyllostachys pubescens) and o-juk (Phyllostachys nigra Munro)] and maengjong-juk extract coated rice were evaluated for antimutagenicity by Ames test using Salmonella typhimurium TA100. Bamboo extracts showed strong antimutagenic activity in the Ames test which MNNG was used as mutagen in the absence and presence of S9 mix. Maengjong-juk extract coated rice diet suppressed the loss of body weight significantly. Food intake was increased in maengjong-juk extract coated rice supplemented group but showed no significant differences between control and maengjong-juk extract coated rice diet groups. Food efficiency of maengjong-juk extract coated rice supplemented group was significantly higher than that of the control group. Liver weight was significantly increased by maengjong-juk extract coated rice diet administration. Plasma GOT & GPT activities of rabbit were significantly suppressed in maengjong-juk extract coated rice supplemented group. These results suggest that bamboo trees extracts and maengjong-juk extract coated rice are bioavailable resource on treatment of cardiovascular disease, such as atherosclerosis and hypercholesterolemia.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.1
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• pp.1-7
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• 2007

Antimutagenic and in vitro anticancer effects of doenjangs added with green tea extract and/or using bamboo salt were studied by Ames test using Salmonella enterica serovar Typhimurium (Salmonella Typhimurium) TA100 and 3-(4,5-dimethylthiazol) -2,5-diphenyltetrazolium bromide (MTT) assay on PC-3 and DU145 human prostate cancer cells, respectively. At the 1.25 mg/plate concentration, 1% green tea extract (GTE) added doenjang exhibited 85% antimutagenicity against aflatoxin $B_1$ ($AFB_1$), while the control doenjang revealed 63% antimutagenicity, showing increased antimutagenic effect by the addition of green tea extract during doenjang fermentation. GTE added doenjang also increased antimutagenic effect against MNNG. The inhibition rate of the control doenjang showed 34% at 0.625 mg/plate, while 1% and 2% GTE added doenjangs inhibited by 56% and 73% at the 0.625 and 1.25 mg/plate, respectively (p<0.05). In MTT assay, GTE added doenjangs caused 70% $\sim$ 77% inhibition on the proliferation of PC-3 human prostate cancer cells at 0.5 mg/mL while the control doenjang exhibited 46% inhibition. However, 2% GTE added doenjang showed 91% inhibition at 1.0 mg/mL. The trend of the inhibition rate was similar in DU14S human prostate adenocarcinoma cells. When bamboo salt was used instead of natural sea salt, the antimutagenicity against MNNG and in vitro anticancer effect on the prostate cancer cells greatly increased. From these results, it can be concluded that green tea extract addition to doenjang and the use of bamboo salt during doengjang preparation increased the antimutagenic and in vitro anticancer activities of the doenjang and showed a synergistic effect.

• Korean Journal of Food Science and Technology
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• v.34 no.6
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• pp.1073-1078
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• 2002

Antimicrobial activities in 70% ethanol extracts of Korean bamboo trees were investigated. Among the antimicrobial activities against ten major strains causing food poisening, Wangdae (Phyllostachys bambusoides S. et Z.) showed the strongest activity among five major bamboo trees cultivated in Korea. Although all extracts showed relatively strong antimicrobial activities against Staphylococcus aureus and Streptoccus mutans, the extracts of bamboo culms showed stronger activities than that of bamboo leaves. MICs (minimal inhibitory concentration) of the extracts of Wangdae culm against Staphylococcus aureus and Streptococcus mutans were over $10\;and\;20\;{\mu}L/disc$, respectively. The extract of Wangdae culm inhibited the growth of Staphylococcus aureus and Streptococcus mutans at over 0.5% concentration, and almost inhibited the growth of these strains at 1% level. The inhibitory effect of the extract of Wangdae culm was not destroyed by heating at 60, 80, and $100^{\circ}C$ for 60 min and at $121^{\circ}C$ for 15 min, suggesting that the component in the bamboo tree was very heat-stable. These results indicate that 70% ethanol extract of Wangdae culm could be useful as a natural antimicrobial agent.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.1
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• pp.135-142
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• 1996

대나무잎(신의대)을 70% ethanol로 $80\pm2^{\circ}C에서$ 추출하고 극성이 다른 4가기 용매로 확분하여 생리활성 및 항균성을 검토하였다. 70% ethanol extract는 높은 항산화력을 나타내었고, 70% ethanol extract로부터 얻어진 각 용매별 추출 획분이 지질과 산화물 생성 억제와 malonaldehyde 생성 억제 효과는 ethyl acetate 획분 $\geq$ diethyl ether 획분 $\geqpetroleum$ ether 획분 > n-butanol 획분 > 수용성 획분의 순이었다. 전자공여능, 아질산염 제거능 및 항보체 활성은 n-butanol 획분이 다른 획분에 비하여 가장 높은 효과를 보였고 70% ethanol extract의 경우에도 전자고영능, 아질산염 제거능 및 항보체 활성이 높게 나타났다. 미생물인 Vib-rio parahaemoluticus, Pseudomonas aeruginosa, Salmonella typhimurium, Enterobacter aerogenes, Staphylococcus aureus 등에서 항균력을 나타내었다.

• Natural Product Sciences
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• v.16 no.4
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• pp.271-279
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• 2010

Systemic lupus erythematosus (SLE) is characterized by systemic inflammation through production of inflammatory mediators and signaling abnormalities between T- and B- cells, leading to autoantibody production and multiorgan injuries. This study was investigated whether bamboo culm extract (BC) attenuates development of lupus systemic inflammation in the early stage in pristane-induced lupus mice. The pristane-induced lupus mice were administrated with BC 0.5 ml/kg or PBS and healthy mice with PBS orally once a day for 14 days. Our results showed that BC remarkably attenuated levels of serum TNF-$\alpha$, IL-6, IL-10, IFN-$\gamma$, $PGE_2$, and VEGF, production of macrophages IL-6 and $PGE_2$ and expression of macrophages IL-6 and COX-2 mRNA in the presence or absence of LPS in pristane-induced lupus mice. Also, BC remarkably reduced expression of CD40L on the splenic T cells and CD80 on the splenic B cells and upregulated the reduced apoptosis of splenic T cells and CD4+ T cells in pristane-induced lupus mice. Therefore, these findings suggest that BC may attenuate early development of lupus systemic inflammation via downregulation of inflammatory mediators and amelioration of abnormal signaling between T cells and B cells.