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Performance of Various Drug-Eluting Stent Geometries Measured Using Computational Analysis (여러 형상을 고려한 약물분출 스텐트의 성능에 대한 수치해석적 연구)

  • Seo, Tae-Won;Barakat, Abdul I.
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.6
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    • pp.601-607
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    • 2012
  • In this study, we performed computational fluid dynamic simulations to explore how the detailed design of drug-eluting stents affects both the flow field in the vicinity of the stent as well as the concentration of the eluted drug at the endothelial cell surface. Simulations were performed on three idealized stent geometries we developed and on geometries approximating three commercial stents,: Medtronic's Aurora stent, Cordis's BX Velocity stent, and Boston Scientific's Wallstent. An important contribution of the present study is the introduction of the stent effectiveness index (EI), which provides a quantitative assessment of stent performance and an objective basis for comparing the performance of different stents. Among the three commercial stents studied, our simulations have revealed that the BX Velocity stent is associated with the lowest in-stent EI values for the range of flow Reynolds numbers studied ($200{\leq}Re{\leq}800$). In addition to commercial stent designs, we investigated the EI in three idealized stents and determined that a spiral stent provides excellent performance (low EI) under all flow conditions investigated.

Ethephon Mixed with Calcium Carbonate Accelerate Coloration of Satsuma Mandarin (Citrus unshiu Marc.) in the Plastic House (에스렐과 탄산칼슘에 의한 하우스 밀감의 착색 촉진)

  • 김용호;문영일
    • Journal of Bio-Environment Control
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    • v.7 no.2
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    • pp.130-138
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    • 1998
  • This experiment was conducted to study the effect of ethephon(100mg.L$^{-1}$ ) and calcium carbonate (10000mg.L$^{-1}$ ) on the acceleration of peel coloration of ‘Miyagawa Early’ Satsuma Mandarin in the plastic house. The foliar application treatments were conducted once. twice or 3 time at intervals of 15 days from degreening of the fruit apex. Peel coloration of a value by spraying ethephon + clef-non was increased with treatment frequency. The a/b values ran similar to this trend. As a result of this, peel coloration was accelerated by foliar application of ethephon + clef-non. Glucose and fructose did not differ significantly among foliar application frequencies. Sucrose and total sugar increased as foliar application frequency increased, but there was no significant di(ference among foliar application frequency group. The brix values were higher than 12˚BX in all treatments. However, a distinct difference between the control Brix value and the values for the treatment groups was found only in the level 3 frequency group.

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Comparison of Takju Characteristics Manufactured using Rosa rugosa Thunb. and Two Different Pre-treatments of Rice (쌀의 전처리 과정을 달리하고 해당화로 가향한 탁주의 발효특성 비교)

  • Han, Woo-Cheul;Lee, Jae-Cheol;Sohn, Eun-Hwa;NamKoong, Seung;Lee, Je-Hyuk;Yu, Jin-Hyun;Jang, Ki-Hyo
    • Journal of the East Asian Society of Dietary Life
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    • v.21 no.4
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    • pp.514-519
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    • 2011
  • Takju was manufactured using 150 g Rosa rugosa Thunb. (Haedanghwa) and two different preparations of 3,000 g each of cooked and uncooked rice. Nuruk (150 g) and yeast (60 g) were inoculated into both mixtures for fermentation, and physiochemical changes were investigated during 14 days of fermentation. The final brix value, pH, and ethanol concentration of Haedanghwa (uncooked rice Takju) were $13.0^{\circ}$Bx, 4.3, and 11.8%, respectively, whereas those of Haedanghwa (cooked rice Takju) were $14.0^{\circ}$Bx, 4.6, and 14.4%, respectively. Lactic and acetic acid levels in Haedanghwa (uncooked rice Takju) were significantly higher than those in Haedanghwa (cooked rice Takju) (p<0.05). The level of ${\gamma}$-amino-n-butyric acid in Haedanghwa Takju (uncooked rice) was twice than that of Haedanghwa Takju (cooked rice). Our results demonstrate that the use of uncooked rice in the preparation of Takju may help improve the taste and function of the final product.

A Study on the Stand Volume Estimation by Strand Method (Strand법(法)에 의한 임분재적추정(林分材積推定)에 관(關)한 연구(硏究))

  • Lee, Heung Kyun
    • Journal of Korean Society of Forest Science
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    • v.80 no.2
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    • pp.187-192
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    • 1991
  • This study was carried out to estimate the stand volume for Japanese larch(Larix leptolepis) by Strand sampling method. The data collected for this study were based on the 380 sample plots from the field survey, which were distributed in the major part of Korea(Kyeongi, Kangweon, Chungbuk, Chungnam, Chunbuk and Kyeongbuki), and the plotless sampling instrument such as dendrometer, spiegel relascope and tele-relascope were used. The procedure for this study is summarized briefly as follows : 1. There were not only significant differences between volume estimation by Strand sampling method and that by plot survey method, and the relationship was y=bx, where b approached nearly 1. Therefore, the stand volume of Japanese larch could by estimated by Strand sampling method. 2. The value measured by three different plotless sampling instruments did not showed any significant differences between instruments and observers, density and instruments, and ground slope and instruments. 3. With the stand volume, basal area height showed the highest correlation and stand form height, average height, basal area per ha correlated with the volume in thier orders. 4. The best fitted equation of stand volume estimation with basal area height by relascope was as follow. log V=-0.0375+0.8910 log GH-1.5946 1/GH Stand volume table also was obtained using the above estimeated equation. 5. The relationship between estimated value and actual value was Y=bx, where b was nearly 1. The correlation coefficient was very high and the percentage of estimated error was 4.5%.

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Physicochemical Properties of Different Grape Varieties Cultivated in Korea (국내에서 재배한 포도 품종간의 이화학적 특성 비교)

  • Ahn, Hyuk-Jin;Son, Hong-Seok
    • Korean Journal of Food Science and Technology
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    • v.44 no.3
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    • pp.280-286
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    • 2012
  • The aim of this study was to describe the effects of genetic factors on the chemical composition or metabolites of grapes harvested within the same region. Grapes were separated into pulp, skin, and seed, and physicochemical characteristics were compared among seven grape varieties. The sugar concentrations of the grape musts ranged from $15.17-20.93^{\circ}Bx$ with Seibel variety being highest at $20.93^{\circ}Bx$. pH ranges of grape musts were 3.46-4.02 and total acidity was highest with 1.05 in Steuben variety. Tartaric acid content was highest with 146.68, 500.10 mg/L in pulp and skin extract of Merlot variety. Malic acid content was highest in pulp extract of Seibel variety (1127.14 mg/L) and skin extract of Chardonnay variety (1720.06 mg/L). K content was highest with 379.13 and 828.01 mg/L in pulp and skin extract of Chardonnay variety. Ca content was highest in pulp extract of Kyoho variety (6.98 mg/L) and skin extract of Campbell Early variety (12.26 mg/L).

Alcohol Fermentation of Uncooked Ground Rice with Ultrasonication Process (초음파를 이용한 무증자 분쇄 백미의 알코올 발효)

  • Lee, You-Jin;Kang, Sung-Tae
    • Korean Journal of Food Science and Technology
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    • v.44 no.3
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    • pp.306-311
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    • 2012
  • This study was performed to evaluate the effects on saccharification and alcohol fermentation, according to the size of the ground rice (12, 20, 35 mesh) and ultra sonication process (15, 30, 60, 120 min). After saccharification of the ground rice samples for 3 h at $60^{\circ}C$, sugar content was observed to be high in the order of cooked ground rice (CGR) > ultrasonicated ground rice (UGR) > ground rice (GR), in all sizes of ground rice. Further, higher sugar content was obtained by increasing the time of ultrasonication process. Almost 90% saccharification of CGR ($11.5^{\circ}Bx$) could be reached up to $10.2^{\circ}Bx$ by ultrasonicating 35 mesh ground rice for 120 min. After alcohol fermentation on the 35 mesh saccharified-UGR for 4 days at $25^{\circ}C$, 16.7% alcohol concentration could be obtained, as high as of CGR (17.2%). After 4 days of alcohol fermentation, UGR showed a lower pH and a higher acidity (pH 4.06-4.17, 0.99-1.1%) than CGR (pH 4.27, 0.75%).

Changes in Fermentative Characteristics of Red Ginseng Wine using Enzymatically Hydrolyzed Red Ginseng Marc (홍삼박 효소분해물을 이용하여 제조한 홍삼주의 발효특성 변화)

  • Kim, Dong Chung;In, Man-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.12
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    • pp.6290-6295
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    • 2013
  • This study examined the fermentative characteristics of red ginseng wine prepared with enzymatically hydrolyzed red ginseng marc (ERGM), which was produced by the polysaccharide hydrolyase and protease treatments of red ginseng marc (RGM). After adjusting the initial soluble solid contents of ERGM broth to $20^{\circ}Brix$ and $30^{\circ}Brix$ with sucrose, respectively, alcohol fermentation was carried out at $25^{\circ}C$ for 9 days. The soluble solid contents decreased from $20^{\circ}Brix$ to $7^{\circ}Brix$ and from $30^{\circ}Brix$ to $13^{\circ}Brix$, and the reducing sugar content decreased to 18 and 24 g/L at 9 days of fermentation, respectively. The ethanol contents increased to 65 g/L and 106 g/L, respectively. The crude saponin content in the ERGM broth was 2~3 times as high as that in the RGM broth after 7 days fermentation. These results show that ERGM is suitable as a raw material for the production of red ginseng wine.

The Effects of Environment-Friendly Agricultural Materials on Soil and the Quality of 'Niitaka' pear's Orchad (친환경농자재 처리가 배과수원 토양 및 과실품질에 미치는 영향)

  • Yoon, Seong-Tak;Xu, Zhen-Yu;Zhang, Qing-Yu;Kim, Tae-Ho;Nam, Jung-Chang;Park, Sang-Hun;Kwak, No-Il;Mun, Su-Hak;Lee, Hyuk-Jae;Choi, Jin-Ho
    • Korean Journal of Organic Agriculture
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    • v.18 no.4
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    • pp.613-626
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    • 2010
  • Coming with the well-being era, consumer's demand for safe agricultural products is increasing. It is urgent to develop an environment-friendly pear production system. Accordingly, this study was conducted to develop an environment-friendly pear production system by using several environment-friendly agricultural materials which is known to be effective in agricultural production. In the effects of environment-friendly agricultural materials on the soil chemical characteristics in pear orchard, the content of total carbon, organic matter, Ca and Mg increased a little respectively compared with those of 2008, and 2nd treatment showed the highest EC and Mg content in the soil among treatments. The content of leaf N, P and Ca in 2009 decreased compared with those of 2008, while Mg content showed no difference between 2008 and 2009 years. Average pear weight in 2009 was 31g higher than that of 2008 (682g) and 2nd treatment showed the highest pear weight (738g) among treatments. The average sugar content was higher in 2009 (12.6$^{\circ}Bx$) compared with that of 2008 (12.2$^{\circ}Bx$) and the plot of 2nd treatment highest sugar content (12.6$^{\circ}Bx$) among treatments. There were no difference in hunter value of L among treatments, but hunter value of a showed higher 1.62 in 2009 than that of 2008 (3.73). The highest of gumminess and cohesiveness of fruits were obtained from 1st treatment and adhesiveness and chewiness of fruits were obtained from 3rd and 1st treatment respectively. Firmness of fruit increased a little in 2009 compared with that of 2008, while the highest firmness was obtained from 3rd treatment with 1.63kg/5mm$\oint$ among treatments. Phosphate content in the peel of 'Niitaka' pear of fruit skin in 2009 (0.97g/kg) showed 0.06g/kg more content than that of 2008 (0.91g/kg), while the highest content was obtained from 3rd treatment (1.15g/kg). Potassium content in the peel of 'Niitaka' pear in 2009 was 8.20g/kg, which is 0.06g/kg more content than that of 2008 (7.82g/kg) and the highest content was obtained from 1st treatment (8.34g/kg) among treatments. The highest nitrogen content in the flesh of 'Niitaka' pear was obtained from 3rd treatment (4.32mg/g), while it was the lowest in control plot (3.10mg/g). Phosphate content in the flesh of 'Niitaka' pear in 2009 (8.20g/kg) showed 0.06g/kg more content than that of 2008 (7.82g/kg), while the highest content was obtained from 1st treatment (8.34g/kg). There were no difference of the potassium content in the fruit peel of 'Niitaka' pear between years, but 1st treatment showed the highest content (11.81g/kg) among treatments, while the lowest was obtained from the control plot (10.83g/kg).

GLOBAL ASYMPTOTIC STABILITY OF A SECOND ORDER RATIONAL DIFFERENCE EQUATION

  • Abo-Zeid, R.
    • Journal of applied mathematics & informatics
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    • v.28 no.3_4
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    • pp.797-804
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    • 2010
  • The aim of this paper is to investigate the global stability, periodic nature, oscillation and the boundedness of solutions of the difference equation $x_{n+1}\;=\;\frac{A+Bx_{n-1}}{C+Dx_n^2}$, n = 0, 1, 2, ... where A, B are nonnegative real numbers and C, D > 0.