• Journal of Chest Surgery
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• v.39 no.5 s.262
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• pp.419-422
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• 2006

Benign symmetric lipomatosis (BSL), also called Madelung's disease, is a rare disease in middle-aged chronic alcohol user. The cause of BSL is unknown. A 63 year-old man with rapid growing lesions in both shoulders for 2 months visited our hospital. Except for cosmetic problem, no abnormal finding was found in blood cell analysis and chemistry; however, excessive fat deposition was found on radiographic findings. Lipoma was revealed in pathologic examination and BSL was diagnosed clinically. Patient is being followed up without any specific problem.

• Journal of Preventive Medicine and Public Health
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• v.38 no.4
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• pp.449-456
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• 2005

Objectives : The biosafety level (BSL) practiced in microbiology laboratories in Korea according to the laboratory biosafety manual published by the World Health Organization (WHO) was evaluated using the data obtained by a survey. Methods : Under the advise of Clinical Laboratory Physicians, 144 types of microorganisms were screened based on the guidelines of biosafety in microbiological and biomedical laboratories published by the US Center for Disease Control and Prevention and classified into 1-4 risk groups. A questionnaire containing 21 questions in 5 areas was developed using the biosafety manual by published WHO. Of the 1,876 different organizations sent the survey, 563 responded to the survey (response rate: 30.0%). The species of microoganisms handled by as well as the biosafety level in microbiology laboratories were analyzed. Results : There were 123 species of microorganisms handled in microbiology labs in Korea. The BSL required in 512 microbiology labs was answered by the survey responders as the first grade in 33 labs (6.4%), 2nd in 437 (85.4%), 3rd in 42 (8.2%), and 4th in none. The average number of items satisfied was 12.2, showing only a 57.9% satisfactory rate and normal distribution. Conclusions : The state of overall observance of BSL in most microbiology labs of Korea was evaluated as lagging compared with the standard set up by WHO. Therefore, the Korean government need to produce and distribute a biosafety manual in microbiology laboratories and make efforts to prevent this threat through measures such as training in biosafety in microbiology labs.

• Safety and Health at Work
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• v.8 no.1
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• pp.49-58
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• 2017

Background: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. Methods: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression. Results: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1-3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE. Conclusions: Current knowledge of laboratory biosafety is limited except among a few researchers.

• The Journal of Engineering Geology
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• v.30 no.3
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• pp.347-378
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• 2020

Based on monthly average groundwater recharge over a nearly 10 year period, results of fully integrated hydrologic modeling of SWAT-MODFLOW, land cover, land use, soil type and hydrologic response unit (HRU) was used to assess the dominant influencing factors of groundwater recharge spatial patterns in Jangseong district. As dominant factors, land cover was FRSE (forest-evergreen) and soil type was Samgag. Landsat-8 OLI imaging spectrometer data were acquired in the period 2003 to 2004 and seasonal bare soil lines (BSL) were estimated through NIR-RED plot. Extent of slope of BSL was from 1.092 to 1.343 and the intercept was from -0.004 to -0.015. To know correlation between spatial groundwater recharge and soil-vegetation indices (PVI, NDVI, NDTI, NDRI), this study employed frequency and regression analysis. On May, RED band increased up 3 to 4 times compared to other seasons and only one turning point appeared as recharge-index with upward parabola bell shape as results of existing research. Considering precipitation, if the various studies for relationship between groundwater recharge and soil-vegetation index just like NDVI are performed, it is possible to estimate groundwater recharge through analyzing remote sensing data.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.2
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• pp.199-200
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• 2021

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.324-329
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• 2005

Dynamic Encoding Algorithm for Searches (DEAS) which is known as a fast and reliable non-gradient optimization method, was proposed [1]. DEAS reaches local or global optimum with binary strings (or binary matrices for multi-dimensional problem) by iterating the two operations; bisectional search (BSS) and unidirectional search (UDS). BSS increases binary strings by one digit (i.e., 0 or 1), while UDS performs increment or decrement of binary strings in the BSS' result direction with no change of string length. Because the interval of UDS exponentially decreases with increment of bit string length (BSL), DEAS is difficult to escape from local optimum when DEAS falls into local optimum. Therefore, this paper proposes hopping UDS (HUDS) which performs UDS by hopping as many as BSL in the final point of UDS process. HUDS helps to escape from local optimum and enhances a probability searching global optimization. The excellent performance of HUDS will be validated through the well-known benchmark functions.

• Biomedical Science Letters
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• v.23 no.3
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• pp.161-165
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• 2017

It has well reported that host immune system is closely related to cancer growth and eradication. Among cancer immunotherapy, cancer vaccine is focused on this review. Cancer vaccine is using host immune system against various tumor antigens to treat cancer. We discuss the classification and characteristics of the preventive vaccine, therapeutic vaccine and combination cancer immunotherapy.

• Biomedical Science Letters
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• v.28 no.4
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• pp.223-228
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• 2022

It has well reported that tumor markers have many advantages like minimally invasive, convenient use, low cost but also has many limitations like low sensitivity and specificity, relevance of prognosis, low organ specificity. Although no tumor markers are ideal, many tumor markers are used for cancer diagnosis, treatment monitoring, and surveillance monitoring after treatment. We review the classification and characteristics of tumor markers according cancer types and clinical roles in current times.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.12
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• pp.1653-1661
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• 2012

In this study, the pressure drop changes and structural characteristics of a SMART rod bundle under the effect of a coolant were investigated. The turbulence model of the BSL Reynolds stress model was used to model the coolant flow, and a fluid solid interaction simulation was conducted. First, fuel rod vibration analysis was performed to confirm the natural frequency of the fuel rod, which was supported by spacer grid assemblies, and this was compared with experimental results. From the experimental results, the natural frequency was found to be 48 Hz, and the error compared with the simulation results was 2%. The pressure drop at the rod bundle was calculated and compared with the experimental data; it showed an error of 8%, demonstrating the simulation accuracy. In the flow analysis, the flow velocity and secondary flow at different domains were calculated, and vortex generation was also observed. Finally, through the fluid solid interaction analysis, the fuel rod displacements caused by flow-induced vibrations were calculated. Then, calculated displacement PSD at maximum displacement happed point.

• Journal of Life Science
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• v.18 no.6
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• pp.782-788
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• 2008

The aim of this work is to show differences in the pattern of glycoconjugate composition in the intestines of four teleostean species (Sebastes schlegeli, Halichoeres poecilopterus, Bryzoichthys lysimus, and Takifugu pardalis). We compared four regions of all species studied. The specimens were processed and stained with nine kinds of biotinylated lectins (DBA, SBA, PNA, BSL- I , RCA- I , sWGA, UEA- I , LCA and Con A). Except for Sebastes schlegeli, no differences between regions were observed. The intestinal epithelium of Halichoeres poecilopterus possessed D-glucose/mannose residues in all regions. ${\beta}$-N-acetyl-D-galactosamine was distinctive along the intestines, although the pattern of diversity was different in Sebastes schlegeli, Bryzoichthys lysimus, and Takifugu pardalis. Additionally, the occurrence of Galactose-${\beta}$-1,3-N-acetyl-D-galactosamine and ${\alpha}$-D-galactose were confirmed in the proximal, middle, and distal intestine of Sebastes schlegeli, while rectal intestine lacked these sugar residues. Along with ${\beta}$-N-acetyl-D-galactosamine, ${\beta}$-N-acetyl-D-glucosamine and D-glucose/mannose were also determined in Bryzoichthys lysimus. Galactose-${\beta}$-1,3-N-acetyl-D-galactosamine, D-galactose, and D-glucose/mannose were also present in Takifugu pardalis.