• KOREAN JOURNAL OF CROP SCIENCE
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• v.62 no.3
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• pp.184-192
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• 2017

Rice flours from five rice (Oryza sativa L.) varieties with different amylose content were prepared by both wet and dry milling processes. The moisture content of wet-milled rice flours (WMR) was approximately three-times higher than that of dry-milled rice flours (DMR). Water absorption index (WAI), water solubility index (WSI), and swelling power (SP) increased in proportion to temperature. The WAI, WSI and SP values of DMR were higher than those of WMR. Baeokchal (BOC), which is a waxy rice cultivar, had a significantly high WSI value. Pasting properties of DMR, except for the BOC cultivar, resulted in an increase in peak, trough, final, and setback viscosities. The levels of resistant starch in four cultivars, except for Dodamssal (DDS), were under 1%, irrespective of the milling process, whereas the resistant starch contents of DMR and WMR in DDS were 9.18% and 6.27%, respectively. In vitro digestibility of WMR was higher than that of DMR, and the estimated glycemic index of the rice flour varieties ranged from 57.6 to 81.3. Damaged starch content of WMR was less than that of DMR; in addition, a negative correlation was observed between the amylose and damaged starch contents of WMR. These results suggest that the properties of rice flour vary depending on the milling method and flour variety, and could be a reference for selecting the appropriate processing method.

• Journal of Life Science
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• v.8 no.4
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• pp.410-415
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• 1998

Procine pepsin hydrolysis of hexapeptide L-S-pNF-Nle-A-OMe in the presence of dipeptide L-L generates a new peak on HPLC analysis of reaction mixtures that is not seen when enzyme is incubated with either peptide alone. The peaks can be detected spectroscopically at either 214 or 254 nm, the latter consistent with a new peptide containing the p-nitro-F residue. The data suggest acyl transpeptidation between E(L-S-pNF) and L-L to form L-S-pNF-L-L. Consistent with this inference are (1) the ability of L-L-NH$_{2}$ and inability of Boc-L-L to undergo a similar transpeptidation reaction, and (2) the data from electrospray mass spectrum. This synthesis requires that Nle-A-L-OMe be released before L-S-pNF, an order opposite to that proposed on the basis of product inhibition kinetics. Consistent with this inference are reciprocal solvent isotope effects ; normal isotope effects of 1.736$\pm$0.121 on the formation of Nle-A-L-OMe and 2.281$\pm$0.184 in the formation of L-S-pNF, coupled to an inverse isotope effects of 0.576$\pm$0.045 on the formation of L-S-pNF-L-L. Because transpeptidation precedes faster in D$_{2}$O, the isotopically-sensitive step must occur after release of Nle-A-L-OMe. Isotopically-enhanced transpeptidation is consistent with the Uni-Bi iso memchanism postulated on the basis of an isotope effects on Vmax but not on Vmax/Km$^{1)}$ and confirmed by isotope effects on the onset of inhibition by pepstatin$^{2)}$.

• Research in Community and Public Health Nursing
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• v.16 no.2
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• pp.196-204
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• 2005

Purpose: This study was to investigate the relation among social support, drinking and smoking and to identify factors affecting high school students' smoking and drinking behaviors. Methods: Data were collected from 361 high school students (182 students in 2 preparatory schools and 179 students in 2 vocational high schools) who were selected through convenient sampling. Data were analyzed using SPSS 11.5 for Windows. Results: Factors affecting smoking behavior were drinking(OR=15.86. p<0.01), school type(R=11.82, p<0.01), school record(OR=46.62. p<0.001), pocket money (OR= 10.91. p<0.01) and brother's smoking (OR=9.09. p<0.05). Factors affecting drinking behavior were smoking(OR=8.32. p<0.01), school type(OR=2.53. p<0.01), school record(OR=2.35. p<0.01), pocket money(OR=2.01. p<0.05), father's educational background(OR=2.126. p<0.05), mother's drinking(OR= 1.83. p<0.05) and relationship with teacher (OR=2.44. p<0.01). Conclusion: The behaviors of drinking and smoking in high school students were highly correlated with each other. School record, school type, pocket money and family member's behaviors influenced student's behaviors. Further study is required to estimate the effect of drinking and smoking intervention programs according to student's characteristics such as school record, school type, pocket money management, and family members' influence.

• Nuclear Engineering and Technology
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• v.45 no.7
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• pp.941-950
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• 2013

The Korean Nuclear-Hydrogen Technology Development (NHTD) Plan will be performing irradiation testing of coated particle fuel at HANARO to support the development of VHTR in Korea. This testing will be carried out to demonstrate and qualify TRISO-coated particle fuel for use in VHTR. The testing will be irradiated in an inert gas atmosphere without on-line temperature monitoring and control combined with on-line fission product monitoring of the sweep gas. The irradiation device contains two test rods, one has nine fuel compacts and the other five compacts and eight graphite specimens. Each compact contains about 260 TRISO-coated particles. The irradiation device is being loaded and irradiated into the OR5 hole of the in HANARO core from August 2013. The device will be operated for about 150 effective full-power days at a peak temperature of about $1030^{\circ}C$ in BOC (Beginning of Cycle) during irradiation testing. After a peak burn-up of about 4 atomic percentage and a peak fast neutron fluence of about $1.7{\times}10^{21}\;n/cm^2$, PIE (Post-Irradiation Examination) of the irradiated coated particle fuel will be performed at IMEF (Irradiated Material Examination Facility). This paper reviews the design of test rod and irradiation device for coated particle fuel, and discusses the technical results for irradiation testing at HANARO.

• Korean Journal of Ecology and Environment
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• v.40 no.3
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• pp.468-480
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• 2007

The urbanization is altering the hydrology, water quality, channel form of waterway and changing the composition of biological communities in the aquatic ecosystem. Recently, towns grew bigger by the drift of large numbers of people and the medium and small leather and dyeing industries around the Pocheon and Youngpyeong streams. The discharges of sewage were increased by them. The UII (urban intensity index) was 85 (st. P-3) and 91 (st. P-6) in the Pocheon stream and about 20 in the Youngpyeong stream. A total 141 taxa of epilithic diatoms which were composed of 2 order, 8 family, 30 genera. Dominant species were Navicula saprophila, N. subminuscula, Nitzschia palea, Gomphonema pseudoaugur in the Pocheon stream and Achnanthes alteragracillima, A. convergens, A. minutissima, N. minima, N. fonticola, N. frustulum and Cymbella minuta var. silesiaca in the Youngpyeong stream. It Showed the different composition of dominant species by the urbanization near two streams. In the relationships between UII and environmental factors such as EC, BOD, COD, TN, TP and DAIpo, UII showed the high relations $(r^2>0.8)$. It was the difference of organic pollution according to urbanization. It therefore, was higher the relative abundance and more the numbers of saprophilous taxa in the Pocheon stream than the Youngpyeong stream. The water quality of two streams by biological indicators(DAIpo) was polysaprobic state(st. P-3, P-4, P-5) in the Pocheon stream and was oligosaprobic (Y-1), mesosaprobic (Y-2, 3) and polysaprobic state (Y-4) in the Youngpyeong stream during the investigation periods.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.11 no.1
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• pp.60-69
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• 2000

Objective：This study was carried out to evaluate the reliability and validity of the Korean form of the Children's Yale-Brown Obsessive Compulsive Scale(CY-BOCS). Method：Forty-two children with obsessive-compulsive disorder(OCD)(31 boys and 11 girls, aged 7 to 18 years) were assessed with CY-BOCS. Interrater agreement was assessed by two raters in subsample(n=20). discriminant and convergent validity were assessed by comparing CY-BOCS scores to Clinical Global Impression-OCD(CGI-OCD), Leyton Obsessional Inventory-Child Version (LOI-CV), State-Trait Anxiety Inventory for Children(STAI-C), and Child Depression Inventory(CDI). Results：Internal consistency was high, measuring 0.86 for the 10 items and total score. The intraclass correlations for the CY-BOCS total, obsession, and compulsion scores were 0.94, 0.94, 0.84, suggesting excellent interrater agreement for subscale and total scores. The CY-BOCS total score showed highest correlation with CGI-OCD(r=0.88), and significant correlation with LOI-CV(r=0.51), Trait Anxiety score(r=0.43), and CDI scores(r=0.49), but it was not correlated with State-Anxiety score(r=0.25). Conclusion：The results of this study indicate that the Korean form of CY-BOCS is a reliable and valid scale for rating obsessive-compulsive symptom severity.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.44-51
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• 2019

This study was performed to explore the difference in communication anxiety and class satisfaction after taking the traditional lecture and flipped learning lecture. Fifty four nursing students participated in this study. The study design was one group pretest-posttest design. 4 weeks traditional lecture and 4 weeks flipped learning lecture was applied. Flipped learning was ineffective in improving communication anxiety (t=1.85, p=.069) of nursing students. But emotional state variables and activity variables in the emotional domain were significantly higher after taking the flipped learning lecture(t=-3.80, p=.000; t=-3.35, p=.001). In addition, all of the variables were higher in the flipped learning based team, in the control of the class activities (t=-3.07, p=.003), personal ability (t=-2.48, p=.016), and class participation(t=-3.25, p=.002). Flipped learning is therefore considered to be effective in training nursing students. This study suggested to investigate the effectiveness of flipped learning and learners' satisfaction.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.5
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• pp.263-270
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• 2006

Purpose: Several radioisotope-labeled thymidine derivatives such as $[^{11}C]$thymidine was developed to demonstrate cell proliferation in tumor. But it is difficult to track metabolism with $[^{11}C]$thymidine due to rapid in vivo degradation and its short physical half-life. 3'-$[^{18}F]$fluoro-3'-deoxythymidine ($[^{18}F]$FLT) was reported to have the longer half life of fluorine-18 and the lack of metabolic degradation in vivo. Here, we described the synthesis of the 3'-$[^{18}F]$fluoro-3'-deoxythymidine ($[^{18}F]$FLT) and compared with $([^{18}F]FET)\;and\;([^{18}F]FDG)$ in cultured 9L cell and obtained the biodistribution and PET image in 9L tumor hearing rats. Material and Methods: For the synthesis of $[^{18}F]$FLT, 3-N-tert-butoxycarbonyl-(5'-O-(4,4'-dimet hoxytriphenylmethyl)-2'-deoxy-3'-O-(4-nitrobenzenesulfonyl)-${\beta}$-D-threopentofuranosyl)thymine was used as a FLT precursor, on which the tert-butyloxycarbonyl group was introduced to protect N3-position and nitrobenzenesulfonyl group. Radiolabeling of nosyl substitued precursor with $^{18}F$ was performed in acetonitrile at $120^{\circ}C$ and deproteced with 0.5 N HCI. The cell uptake was measured in cultured 9L glioma cell. The biodistribution was evaluated in 9L tumor bearing rats after intravenous injection at 10 min, 30 min, 60 min and 120 min and obtained PET image 60 minutes after injection. Results: The radiochemical yield was about 20-30% and radiochemical purity was more than 95% after HPLC purification. Cellular uptake of $[^{18}F]$FLT was increased as time elapsed. At 120 min post-injection, the ratios of tumor/blood, tumor/muscle and tumor/brain were $1.61{\pm}0.34,\;1.70{\pm}0.30\;and\;9.33{\pm}2.22$, respectively. The 9L tumor was well visualized at 60 min post injection in PET image. Conclusion: The uptake of $[^{18}F]$FLT in tumor was higher than in normal brain and PET image of $[^{18}F]$FLT was acceptable. These results suggest the possibility of $[^{18}F]$FLT at an imaging agent for brain tumor.