• 한국환경농학회지
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• 제35권2호
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• pp.121-127
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• 2016

BACKGROUND: Anaerobic digestion is the most feasible technology because not only the energy embedded in organic matters can be recovered, but also they are stabilized while being degraded. This study carried out to improve methane yield of slaughterhouse wastewater treatment sludge cake by the thermal pre-treatment prior to anaerobic digestion.METHODS AND RESULTS: Slaughterhouse wastewater treatment sludge cake was pre-treated by the closed hydrothermal reactor at reaction temperature of 190℃. BMPs (Biochemical methane potential) of the thermal hydrolysate was tested in the different S(Substrate)/I(Inoculum) ratio conditions. COD(Chemical oxygen demand) and SCOD(Soluble chemical oxygen demand) contents of thermal hydrolysate were 10.99% and 10.55%, respectively, then, the 96.00% of COD was remained as a soluble form. The theoretical methane potential of thermal hydrolysate was 0.51 Nm³ kg^-1-VS_added. And BMPs were decreased from 0.56 to 0.22 Nm³ kg^-1-VS_added when S/I ratio were increased from 0.1 to 2.0 in the VS content basis. Those were decreased from 0.32 to 0.13 Nm³ kg^-1-COD_added when S/I ratio were increased from 0.1 to 2.0 based on COD content. The anaerobic degradability of VS basis have showed 196.9%, 102.2%, 80.7%, 67.4%, and 39.4% in S/I ratios of 0.1, 0.3, 0.5, 1.0, and 2.0, respectively. Also the COD of 119.6%, 76.3%, 70.1%, 69.0%, and 43.1% were degraded anaerobically in S/I ratios of 0.1, 0.3, 0.5, 1.0, and 2.0, respectively.CONCLUSION: BMPs obtained in the S/I ratios of 0.1 and 0.3 was overestimated by the residual organic matters remaining at the inoculum. And inhibitory effect was observed in the highest S/I ratio of 2.0. The optimum S/I ratios giving reasonable BMPs might be in the range of 0.5 and 1.0 in S/I ratio. Therefore VS biodegradability of thermal hydrolysate was in 67.4-80.7% and COD biodegradability showed 69.0-70.1%.

• 한국물환경학회지
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• 제30권6호
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• pp.638-646
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• 2014

Soil erosion from agricultural fields leads to various environmental problems weakening the capabilities of flood control and ecosystem in water bodies. Regarding these problems, Ministry of Environment of South-Korea prepared various structural and non-structural best management practices (BMPs) to control soil erosion. However, a lot of efforts are required to monitor and develop BMPs. Thus, modeling techniques have been developed and utilized for these issues. This study estimated the effectiveness of BMPs which are a vegetation mat with infiltration roll and Roll type vegetation channel using Soil and Water Assessment Tool (SWAT) model through the adjustment of the conservation practice factors, P factors, for Universal Soil Loss Equation which were calculated by monitoring data collected at the segment plots. Each BMP was applied to the areas with slopes ranged from 7% to 13% in the Haeanmyeon watershed. As a result of simulation, the vegetation mat with infiltration roll and Roll type vegetation channel showed 55% and 59% efficiency of soil erosion reduction, respectively. Also, Vegetation mat with infiltration roll and Roll type vegetation channel showed each 11.2% and 11.8% efficiency in reduction of sediment discharge. These roll type vegetation channel showed greater efficiency of soil erosion reduction and sediment discharge. Based on these results, if roll type vegetation channel is widely used in agricultural fields, reduction of soil erosion and sediment discharge of greater efficiency would be expected.

• 대한환경공학회지
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• 제35권9호
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• pp.643-653
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• 2013

본 연구에서는 불투수성 지역에서 강우시 비점오염원 유출특성을 파악하고, 다양한 해석방법을 통하여 비점오염물질의 초기유출현상을 규명하고자 하였다. 불투수성 지역에서의 강우사상 특성은 강우강도의 영향을 많이 받는 것으로 나타났으며, 강우강도가 크면 초기유출현상이 뚜렷하게 나타나는 것으로 나타났다. 또한 선행무강우일수에 의해서 비점오염물질의 농도차가 큰 것으로 나타나, 이에 대한 대책 마련이 필요할 것으로 판단된다. 비점오염원의 초기유출에 의한 감소율(DR) 평가 결과, 강우시 불투수성 지역에서의 비점오염 유출특성은 건기시 불투수면에 집적되어 있던 비점오염물질이 초기강우에 의해 높은 농도로 유출되는 경향을 보였기 때문에 초기강우로 인한 비점오염물질에 대한 대책을 마련하는 것은 중요하고, 이와 관련하여 비점오염 처리시설에 대한 용량 산정에 대한 평가도 필요할 것으로 판단된다. 초기유출에 의한 감소율(DR) 경향 분석은 비점오염물질에 대하여 감소율(DR) 50%를 기준으로 조사지점별 강우유출시간을 분석하였는데, TSS는 15~60 min으로 나타났으며, 유기물질은 30~90 min으로 나타나는 경향을 보였지만 강우유출이 끝날 때까지도 감소율(DR)이 50% 이하인 특성도 나타났다. 이를 근거로 하여 향후 구조적 BMPs 시설 설계 시 참고자료로 활용할 수 있을 것으로 판단된다.

• 한국습지학회지
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• 제9권3호
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• pp.35-42
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• 2007

최근 환경부의 환경정책은 수질오염총량관리제도의 전국적인 확대를 앞두고 다양한 토지이용에서 발생되는 비점오염물질의 관리를 추진하고 있다. 이러한 환경정책의 변화와 함께 4대강 수계에 비점오염원 시범사업을 통해 다양한 비점오염저감시설의 효율평가 및 시설의 유지관리에 대하여 모니터링도 수행하고 있다. 따라서 본 연구는 한강수계에 설치된 비점오염 저감시설 중에서 전처리 시설로 설치되어 있는 침강지 또는 침사지 퇴적물의 물리화학적 성상을 연구함으로써 폐기물로써의 퇴적물 관리에 대한 기초자료를 제시하고자 한다. 일반적으로 비점저감시설의 전처리 시설로 사용되는 침강지는 일정한 체류시간을 제공함으로써 강우유출수내의 입자상 물질을 제거함과 동시에 비점저감시설 내의 여과재 및 침투재의 폐색을 예방하고자 설치되는 전처리 시설이다. 침강지 퇴적물의 물리화학적 특성 연구 결과에 의하면, 일반적으로 Zn과 Cd은 $75{\mu}m$이하의 퇴적물 입도분포에서 입자 표면적으로의 흡착농도가 높은 것으로 나타났다. 중금속 부하량을 살펴본 결과, 입자의 크기가 $425-850{\mu}m$범위 일 경우 중금속 농도가 가장 높게 나타났다. 전체 중금속에 대한 분석 결과, Cu, Zn, Pb의 중금속 함량이 입도분포 $425-850{\mu}m$ 사이에서 30% 이상을 나타내었다. 중금속 중에서 다른 항목에 비하여 Cu, Pb 및 Zn의 함량이 높게 나타났는데, 이는 차량의 타이어와 엔진파트에 이러한 중금속이 많이 함유되어 있기 때문이다. 또한 본 연 구결과 침강지는 퇴적물의 퇴적과 함께 다양한 중금속의 제거가 발생하는 것으로 나타났다.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2002년도 가을 학술발표논문집
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• pp.96-97
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• 2002

Primordial germ cells (PGCs) are the progenitors of the sperms or eggs of adult. Evidence suggests that the specification of primordial germ cells (PGCs) in the mammalian embryo does not depend on maternal determinants. Recent previous studies in the mouse has shown that several bone morphogenetic proteins (BMPs) are required for the formation of PGCs. However, there is no study about the effect of BMPs on avian PGCs. Here, we studied the effects of recombinant human BMP-2 (rhBMP-2) and recombinant human BMP-4 (rhBMP-4) on chicken blastodermal cells in culture. As a results, the addition of rhBMP-2 and rhBMP-4 increased the number of SSEA-1 positive cells in dose-dependent manner. However, there is no synergic effect by using both rhBMP-2 and rhBMP-4.

• 한국물환경학회지
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• 제24권2호
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• pp.180-184
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• 2008

A distributed hydrologic model of an urban drainage area on Bugok drainage area in Oncheon stream was developed and combined with a optimization method to determine the optimal location and number of best management practices (BMPs) for storm water runoff reduction. This model is based on the SCS-CN method and integrated with a distributed hydrologic network model of the drainage area using system of 4,211 hydrologic response units (HRUs). Optimal location is found by locating HRU combination that leads to a maximum reduction in peak flow at the drainage outlet in this model. The results of this study indicate the optimal locations and numbers of BMPs, however, for more exact application of this model, project cost and SCS-CN reduction rate of structural facilities such infiltration trench and pervious pavement will have to be considered.

• 한국농공학회논문집
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• 제54권2호
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• pp.87-94
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• 2012

This study is to evaluate flood inundation and to recommend measures of damage reduction on sediment by concentrated torrential rainfall at Gonjiamcheon Watershed (183.4 $km^2$). Firstly, the SWAT (Soil and Water Assessment Tool) was simulated streamflow and sediment at upstream. Then, we produced a map of floodplain boundary by using HEC-RAS (Hydrologic Engineering Centers River Analysis System) at downstream. The SWAT model was calibrated with 2 years (2008~2009) daily streamflow and validated for another years (2010~2011. 7. 31). The SWAT model was simulated with 3 years (2008~2010) by monthly water quality (Sediment) at Gonjiamcheon water quality station. The streamflow and sediment from SWAT model were input as boundary conditions to HEC-RAS. The results of HEC-RAS indicated that mapping of floodplain boundary was Jiwol and Jiwol 2 district. Additionally, inundation area and depth were assessed and applied BMPs scenario for managing the sediment yield.

• 대한치과의사협회지
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• 제53권1호
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• pp.14-27
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• 2015

BMPs are multi-functional growth factors which are members of the transforming growth factor-beta super family and their ability is that plays a pivotal roll in inducing bone. About 18 BMP family members have been identified and characterized. Among of them, BMP-2 and BMP-7 have significant importance in bone development. In this case reports, patients of maxillary sinus graft were received who visited LivingWell Dental Hospital. We focused on the results of the surgical intervention. We suggest that new strategy of treatment used to rhBMP-2 and ${\beta}$-TCP scaffold for patients of sinus graft. The purpose of this paper is to give a brief overview of BMPs and to critically review the clinical data currently available on rhBMP-2 and synthetic bone scaffold.

• International Journal of Industrial Entomology and Biomaterials
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• 제32권2호
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• pp.49-53
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• 2016

Bone morphogenetic proteins (BMPs) are essential growth factors for bone formation, skeletal development and bone regeneration. The BMP-2/7 heterodimer is known to have remarkable effects on osteogenic induction that are even stronger than the BMP-2 or BMP-7 homodimers. We designed a recombinant human BMP-2/7 (rhBMP-2/7) heterodimer protein with four glycine residues between BMP-2 and BMP-7 protein to facilitate free bond rotation of domains. The Baculovirus Expression Vector System (BEVS) is routinely used to produce recombinant proteins in the milligram scale. In this study, the BEVS was used to express the rhBMP-2/7 protein whrer the recombinant baculovirus was recovered in the host Sf9 cells. To confirm the biological activity of rhBMP-2/7 protein secreted from the BEVS as an osteogenic differentiation and induction factor, we measured the BMP-induced ALP activity. rhBMP-2/7 could be used as an alternative to BMPs to overcome limitations like short half-life and requirement for high concentrations. Furthermore, rhBMP-2/7 may be an efficient tool for various application studies such as bone regeneration and skeletal development.

• 생명과학회지
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• 제22권4호
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• pp.456-465
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• 2012

유전자 재조합 이형이합체 인간 뼈 형성촉진인자(rhBMP)들은 뼈 재생을 위한 조직공학연구에 중요한 요소들이다. 그러나 실제 뼈 재생에 관한 연구를 수행함에 이들을 이용하는 것은 뼈 형성 촉진인자들이 짧은 반감기를 가지며 비교적 고농도의 단백질을 사용해야 하기 때문에 그만큼 많은 비용이 소요된다는 문제점을 가지고 있다. 이러한 한계를 뛰어넘기 위하여, 본 연구에서는 단백질 전달 서열(PTD)이 융합된 인간 뼈 형성촉진인자 2와 7이 이형이합체 유전자 재조합 단백질(rhBMP2/7-PTD)을 발현하는 세포주를 확립하였다. 이형이합체의 형성은 BMP 2와 BMP 7 단백질 및 PTD 영역의 사이에 각각 4개의 glycine 아미노산 염기서열이 첨가될 수 있도록 하여 각 단백질의 folding이 자유롭도록 디자인하였다. 이렇게 개발된 세포주는 고농도의 rhBMP2/7-PTD을 지속적으로 발현하여 배양액 내로 분비함으로 조직공학용 연구 및 개발에 효율적으로 이용 할 수 있다. 이상의 세포주에서 발현된 rhBMP2/7-PTD 단백질은 뼈 세포분화 유도를 확인 할 수 있는 ALP 활성을 나타냄으로써 뼈 성장촉진 단백질로서 생물학적인 활성을 가지고 있음을 보였다. 본 연구의 결과로 개발된 rhBMP2/7-PTD 형질전환 세포주는 향후 뼈 조직 재생과 같은 연구에 중요하고 효과적인 도구로 이용될 수 있을 것으로 사료된다.