• 한국응용과학기술학회지
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• 제41권2호
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• pp.219-232
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• 2024

이 연구는 성인 여성을 대상으로 체질량지수와 드러밍 운동이 자율신경계에 미치는 영향을 규명하는데 목적이 있다. 30-50대의 성인 여성10명을 체질량지수가 정상인 집단(Low BMI, LBMI <23kg/m²)과 과체중 이상인 집단(High BMI, HBMI>23kg/m²)으로 나누어 드러밍 운동을 실시하였다. 드러밍 운동은 1회 50분, 주 3회, 8주간 실시하였으며, 운동 전후 신체조성과 심박변이도를 측정하였다. 심박변이도는 선형분석인 시간 영역 분석과 주파수 영역 분석을 통해 SDNN(Standard Deviation of NN interval), RMSSD(Root Mean Square of the Successive Differences), HF(High Frequency), LF(Low Frequency), TP(Total Power)를 측정하였다. 비선형분석인 푸앵카레 플롯(Poincaré plot)을 통해 SD1(Standard Deviation of the distance of each point from the y = x axis), SD2(Standard Deviation of each point from the y = x + average R-R interval), SD2/SD1을 측정하였다. 자율신경계 지수로 부교감신경계지수(Parasympathetic Nervous System Index; PNS Index)와 교감신경계지수(Sympathetic Nervous System; SNS Index)를 측정하였다. 연구 결과, 운동 전 심박변이도에서 HBMI 집단과 LBMI 집단 간에는 유의한 차이가 나타나지 않았다. 그러나, 8주간의 드러밍 운동 후에는 HBMI 집단이 LBMI 집단에 비해 체중(p=0.034), 체질량지수(p=0.044), 체지방량(p=0.032), 허리둘레(p=0.013)에서 유의한 상호작용 효과가 나타났다. 심박변이도에서 HBMI 집단은 LBMI 집단에 비해 선형 분석에서 RMSSD(p=0.018)와 TP(p=0.033), 비선형분석에서는 SD1(p=0.018), 자율신경계지수에서는 PNS Index(p=0.040)가 유의하게 증가하였다. RMSSD, SD1 및 PNS Index는 부교감신경계의 활동을 나타내는 지표이다. 결론적으로 8주간의 드러밍 운동이 과체중 이상 여성의 자율신경계 중 부교감신경계의 개선에 긍정적인 효과를 미치는 것으로 확인되었다.

• Journal of Korean Neurosurgical Society
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• 제51권2호
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• pp.81-85
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• 2012

Objective : The purpose of this prospective study was to evaluate the effects of body mass index (BMI) on intra-abdominal pressure (IAP) and intraoperative blood loss (IBL) during lumbar spinal surgery. Methods : Thirty patients scheduled for single level posterior lumbar interbody fusion were allocated equally to a normal group (Group 1, BMI;$18.5-22.9kg/m^2$), an overweight group (Group 2, BMI; $23-24.9kg/m^2$), and an obese group (Group 3, BMI; $25.0-29.9kg/m^2$) according to BMI. IAP was measured using a urinary bladder catheter; 1) supine after anesthesia induction, 2) prone at skin incision, 3) prone at the end of surgery. In addition, IBL was also measured in the three groups. Results : IAP in the supine position was not significantly different in groups 1, 2, and 3 (2.7 mm Hg, 3.0 mm Hg, and 4.2 mm Hg, respectively) ($p$=0.258), and IAP in the prone position at incision increased to 7.8 mm Hg, 8.2 mm Hg, and 10.4 mm Hg, respectively, in the three groups, and these intergroup differences were significant, especially for Group 3 ($p$=0.000). IAP at the end of surgery was slightly lower (7.0 mm Hg, 7.7 mm Hg, and 9.2 mm Hg, respectively). IBLs were not significantly different between the three groups. However, IBLs were found to increase with IAP in the prone position ($p$=0.022) and BMI ($p$<0.05). Conclusion : These results show that BMI affects IAP in the prone position more than in the supine position during lumbar spinal surgery. In addition, IBLs were found to increase with IAP in the prone position and with BMI. Thus, IBLs can be expected to be higher in morbidly obese patients due to an increased IAP.

• 한국방사선학회논문지
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• 제5권6호
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• pp.363-367
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• 2011

일반적으로 중년여성의 골다공증은 저체중에서 발생률이 높은 것으로 보고되었으나 비만인 경우에도 발생할 수 있다. 따라서 본 연구의 목적은 골밀도 검사에서 골다공증으로 진단받은 중년여성 120명을 대상으로 골다공증과 체질량지수의 상관관계를 비교하고자 하였다. 체질량지수가 18.5 미만을 저체중, 18.5 ~ 22.9를 정상, 23.0 ~ 24.9를 과체중, 25.0 ~ 29.9를 비만, 30.0 이상인 경우를 고도비만으로 하였다. 연구 결과 대상자의 체질량지수 분포는 저체중이 2명(1.7%), 정상이 18명(15.0%), 과체중이 19명(15.8%), 비만이 75명(62.5%), 고도비만이 6명(5.0%) 이었다. 또한 체질량지수와 골다공증의 상관관계는 체질량지수가 정상인 경우 18명 중 13명(72.2%)이 골다공증이었으며 과체중의 경우 19명 중 14명(73.7%), 비만의 경우 75명 중 63명(84%), 고도비만의 경우 6명 중 5명(83.3%)로 나타나 체질량지수가 비만인 경우에서 골다공증 발생률이 높았다. 결론적으로 중년여성의 골다공증은 체질량지수가 비만일수록 골다공증 환자가 많다는 것을 알 수 있었으며 대부분 골감소증보다는 골다공증이 높게 나타남을 알 수 있었다.

• 대한치매학회지
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• 제21권1호
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• pp.30-41
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• 2022

Background and Purpose: In this study we aimed to find the association between neuropsychological performance and body mass index (BMI) in patients with mild cognitive impairment (MCI). In addition, we investigated the effects of the apolipoprotein E (APOE) genotype in the relationship between the BMI and cognition in MCI. Methods: We enrolled a cohort of 3,038 subjects with MCI aged 65-90 from the Clinical Research Center for Dementia of South Korea and a dementia cohort of the Ewha Womans University Mokdong Hospital. MCI patients were classified into three subgroups according to the Asian standard of BMI. We compared cognitive performances between groups by one-way analysis of variance. To investigate the effects of the APOE genotype, we used multivariate linear regression models after adjusting for possible confounders. Results: Even though normal BMI groups were younger, had more females, and had less comorbidities, the higher BMI groups had better cognitive functions. Among subjects with APOE ε4 carriers, there was a positive relationship between the BMI and the memory task alone. Conclusions: Our findings suggested that higher BMI in patients with MCI were associated with better cognitive performance. The effects of the APOE ε4 genotype in the associations between BMI and cognition were distinguishing. Therefore, according to physical status, APOE ε4 genotype-specific strategies in the assessments and treatments may be necessary in elderly patients with MCI.

• 복식
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• 제66권8호
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• pp.33-45
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• 2016

This study classified respondents by degree of obesity using Body Mass Index(BMI) and investigated the differences in self-esteem, food lifestyle, social-cultural attitudes towards appearance, and diet-related attitude and behavior such as trial number of diet, exercise time and period, use of diet information, interest in weight control, diet motivation, and dietetic therapy. A survey was conducted with 258 adults between the ages of 20 and 29 who lived in Daegu and Uijeongbu from November $17^{th}$ to December $14^{th}$ 2014. Data collected from the respondents were analyzed using descriptive statistics, factor analyses, analyses of variance and chi-square tests. This study divided the respondents into three groups (the underweight, the normal weight, the overweight) according to Body Mass Index. The results showed that there were significant differences in food lifestyle (health-conscious, popularity-seeking, taste-seeking), social-cultural attitudes towards appearance, exercise time and period, use of diet information, interest in weight control, diet motivation, and dietetic therapy among groups classified by degree of obesity. However, there were no differences in self-esteem, convenience-seeking, and trial number of diet among them.

• 대한영양사협회학술지
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• 제8권2호
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• pp.185-198
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• 2002

The purpose of this study was to compare food habits and nutrient intakes with body mass index of hypertensive patients commuting to a Local Health Center. A total of 85 patients were divided into two groups according to BMI. The non-obese group comprised 43 subjects with BMI below 25㎏/$m^2$ , while the obese group comprised 42 subjects with BMI above 25㎏/$m^2$ . All Subjects were interviewed for general characteristics, food habits, clinical characteristics, effort for health maintenance and the knowledge of hypertension and nutrition. Anthropometric assessments such as weight, height, waist-hip ratio and biochemical measurement of blood urea nitrogen, creatinine, triglyceride, total cholesterol, HDL-cholesterol and fasting blood glucose(FBG) were obtained from subjects. In general characteristics, smoking, drinking, exercise, and hypertension status were not significantly different between the two groups. Food habits and the means of daily energy and nutrients were not significantly different between the two groups. An analysis of the percentage of RDA(Recommended Dietary Allowances of Korea, 2000) consumed by patients showed that but for ascorbic acid and phosphorus, all nutrients were below the RDA. And intakes of vitamin $B_1$(P<0.001), vitamin $B_2$(P<0.01), niacin(P<0.001) of the obese group were significantly lower than that of the non-obese group. Blood urea nitrogen, creatinine, triglyceride, total cholesterol, HDL-cholesterol and fasting blood glucose were in the normal range and there was not a significant difference in the two groups. Therefore, more effective nutrition education programs about exercise, smoking, caloric intake, vitamins and minerals are required for hypertensive patients commuting to Local Health Center.

• Molecular & Cellular Toxicology
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• 제4권1호
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• pp.5-10
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• 2008

The effect of obesity on the drug-metabolizing enzymes remains an important issue for clinician since obesity is a world wide epidemic problem. However, little is known about the effects of obesity on flavincontaining monooxygenase (FMO) production and activity. We show here for the first time that in vivo FMO activity determined by urinary ranitidine (RA) metabolites ratio in human, was higher in subjects with a high body mass index (BMI, kg/$m^2$, 21.97-30.32) than in those with an intermediate BMI (range 19.38-21.83). Moreover, there was a significant correlation between FMO activity and BMI in 209 subjects. In high fat diet-induced obese mice, we also observed that the hepatic expression of FMO (225% of lean mice) and the activity measured by the RA Noxidation rate ($513{\pm}58.1$ vs. $349{\pm}66.0$ pmol/hr per mg protein) were significantly higher than in lean mice fed a control diet. Unknown factors rather than leptin or insulin appeared to regulate the hepatic FMO production. Thus, FMO activity may be increased in obese or overweight individuals. Moreover, the regulation of FMO activity in subjects with morbid obesity, with or without complications and its clinical implications, should be investigated further.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7665-7671
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• 2014

Objectives: The association between body mass index (BMI) and ovarian cancer risk is unclear and requires further investigation. The present meta-analysis was conducted to assess the effect of overweight and obesity on ovarian cancer risk in the premenopausal and postmenopausal periods. Data sources: Major electronic databases were searched until February 2014 including Medline and Scopus. Reference lists and relevant conference databases were searched and the authors were contacted for additional unpublished references. Review Methods: All cohort and case-control studies addressing the effect of BMI on ovarian cancer were included, irrespective of publication date and language. The effect measure of choice was risk ratio (RR) for cohort studies and odds ratio (OR) for case-control studies. The results were reported using a random effects model with 95% confidence intervals (CIs). Results: Of 3,776 retrieved studies, 19 were ultimately analyzed including 10 cohort studies involving 29,237,219 person-years and 9 case-control studies involving 96,965 people. The results of both cohort and case-control studies showed being overweight and obesity increased the risk of ovarian cancer compared to women with normal weight during both premenopausal and postmenopausal periods: RR=1.08 (95%CI: 0.97, 1.19) and OR=1.26 (95%CI: 0.97, 1.63) for overweight and RR=1.27 (95%CI: 1.16, 1.38) and OR=1.26 (95%CI: 1.06, 1.50) for obesity. Conclusions: There is sufficient evidence that an increase in BMI can increase the risk of ovarian cancer regardless of the menopausal status, mimicking a dose-response relationship although the association is not very strong.

• Annals of Clinical Neurophysiology
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• 제8권2호
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• pp.152-157
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• 2006

Background: Meralgia paresthesia (MP) is characterized by sensory impairment in the anterolateral aspect of the thigh and usually caused by a lateral femoral cutaneous nerve (LFCN) lesion. It is well known that several physiologic factors including age, obesity, and sex can affect nerve conduction. This study aimed to determine whether body mass index (BMI) and age can influence on the conduction velocity and action potential amplitude of the LFCN. Methods: Fifty six individuals without any previous neuromuscular disease participated in this study. LFCN was studied orthodromically, distally from the anterior superior iliac spine. The values, such as sensory nerve action potential (SNAP) amplitude and sensory nerve conduction velocity (NCV) were obtained. SNAP of the LFCN were formed on both sides in forty three individuals. Results: No difference of demographic factors was observed between two groups divided according to the presence of SNAP formation. BMI had a significant relationship with SNAP amplitude and NCV of the LFCN. Moreover, Multiple regression analyses of nerve conduction values showed the significant correlation of body mass index and age with nerve conduction velocity. Conclusions: We may suggest that nerve conduction of the LFCN can be affected by age and BMI. Further study to obtain normal nerve conduction data and compare these data with those of meralgia paresthetica patients should be continued.

• 한국보건간호학회지
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• 제33권1호
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• pp.85-97
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• 2019

Purpose: The purpose of this study was to examine the mediating effect of physical activity, dietary habit, and academic stress, as well as the moderating effect of gender on the relationship between adolescents' quality of sleep and body mass index (BMI). Methods: The data were collected from 181 adolescents and analyzed using SPSS WIN 23.0. Bootstrapping analysis was performed to analyze the mediating and moderating effects. Results: First, there was non-significant mediating effect between the quality of sleep and BMI. Second, there was significant moderating effect between the quality of sleep and BMI. Conclusion: Sleep quality should be considered as a component of an intervention program for the prevention and management of obesity. It is also necessary to consider then gender when constructing such program.