• Title/Summary/Keyword: BLG

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Gas Fuelled Ship - Current Status of IGF Code Development at IMO (Gas Fueled Ship - IMO의 IGF Code 개발 동향)

  • Kang, Jae-Sung;Kang, Ho-Keun;Kim, Ki-Pyoung;Park, Jae-Hong;Choung, Choung-Ho
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2011.06a
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    • pp.3-6
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    • 2011
  • The utilization of gas as ship fuel requires a new set of regulations by IMO and society of classification. Maritime Safety Committee(MSC) and the subcommittee Bulk-Liquids and Gases(BLG) in IMO developed "Interim Guidelines on Safety for Natural Gas-fueled Engine Installation in Ships(Res.MSC.285(86))" for the use of natural gas in internal combustion engine. According to the requirement of Res.MSC.285(86) for natural gas-fueled engine installations in ships, several parts of ships should follow safety criteria in terms of Fuel bunkering, Gas safe Machinery spaces, Gas Fuel Storage and etc. In this thesis, details of the IGF code shall be described and development of the IGF code in IMO shall be illustrated.

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Induction of Regulatory Dendritic Cells by Lactobacillus paracasei L9 Prevents Allergic Sensitization to Bovine β-Lactoglobulin in Mice

  • Yang, Jing;Ren, Fazheng;Zhang, Hao;Jiang, Lu;Hao, Yanling;Luo, Xugang
    • Journal of Microbiology and Biotechnology
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    • v.25 no.10
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    • pp.1687-1696
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    • 2015
  • Supplementation with probiotics can protect against the development of food allergies by modulating the host immune response; however, the mechanisms are not fully understood. The objective of this study was to investigate the allergy-reducing effects of regulatory dendritic cells (regDCs) induced by Lactobacillus paracasei L9 (L9) in β-lactoglobulin (BLG)-sensitized mice. The L9 supplement suppressed the aberrant balance of Th1/Th2 responses to BLG in mice, via upregulation of the CD4+CD25+Foxp3+Treg cell responses. The amount of CD4+CD25+Foxp3+Treg cells in mesenteric lymph nodes increased by 51.85%. Furthermore, administration of L9 significantly induced the expression of CD103 and reduced the maturation status of DCs in mesenteric lymph nodes, Peyer's patches, and spleen. Bone marrow-derived dendritic cells (BM-DCs) were activated by L9 in vitro, with an approximate 1.31-fold and 19.57-fold increase in expression of CD103 in CD11c+DCs and the level of IL-10 production, respectively, while the expression of CD86 did not change significantly. These data demonstrate that L9 reduced the BLG allergic sensitization, likely through regDCs mediated active suppression.

OGLE-2015-BLG-1482L:The first isolated Galactic bulge microlens

  • Chung, Sun-Ju;Zhu, Wei;Udalski, Andrzej;Lee, Chung-Uk;Ryu, Yoon-Hyun;Jung, Youn Kil;Shin, In-Gu;Yee, Jennifer C.;Hwang, Kyu-Ha;Gould, Andrew
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.1
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    • pp.44.1-44.1
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    • 2017
  • The single lens event OGLE-2015-BLG-1482 has been simultaneously observed from two ground-based surveys and from Spitzer. The Spitzer data exhibit finite-source effects due to the passage of the lens close to or directly over the surface of the source star as seen from Spitzer. Thanks to measurements of the microns parallax and the finite-source effect, we find that the lens of OGLE-2015-BLG-1482 is a very low-mass star with the mass $0.10{\pm}0.02M{\odot}$ or a brown dwarf with the mass $55{\pm}9MJ$, which are respectively located at $DLS=0.80{\pm}0.19kpc$ and $DLS=0.54{\pm}0.08kpc$, and thus it is the first isolated low-mass microlens that has been located in the Galactic bulge. The degeneracy between the two solutions is severe. The fundamental reason for the degeneracy is that the finite-source effect is seen only in a single data point from Spitzer and this single data point gives rise to two ${\rho}$ solutions.

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Analysis of International Standardization Trend for the Application of Fuel Cell Systems on Ships (선박용 연료전지 시스템 도입을 위한 국제 표준화 동향 분석)

  • Park, Sang-Kyun;Youn, Young-Min
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.5
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    • pp.579-585
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    • 2014
  • For the application of fuel cell systems on ship which is future eco-friendly ship technology, it is need that the modification of relevant laws and regulations with relevant technical development. This paper reviews the trend of fuel cell development, SOLAS and IACS UR/UI as a international regulations, international standardization trend such as IMO MEPC, IMO BLG and major classification rules, the consideration for the standard development of ship fuel cell systems, the implications for application of fuel cell systems on ships in Korea. The IGF Code which is developing in the IMO included fuel cell, and thus Korean government and related company should participate in the codification. The analysis of development of IMO's relevant regulations also needed for the preparations.

High-velocity ballistics of twisted bilayer graphene under stochastic disorder

  • Gupta, K.K.;Mukhopadhyay, T.;Roy, L.;Dey, S.
    • Advances in nano research
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    • v.12 no.5
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    • pp.529-547
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    • 2022
  • Graphene is one of the strongest, stiffest, and lightest nanoscale materials known to date, making it a potentially viable and attractive candidate for developing lightweight structural composites to prevent high-velocity ballistic impact, as commonly encountered in defense and space sectors. In-plane twist in bilayer graphene has recently revealed unprecedented electronic properties like superconductivity, which has now started attracting the attention for other multi-physical properties of such twisted structures. For example, the latest studies show that twisting can enhance the strength and stiffness of graphene by many folds, which in turn creates a strong rationale for their prospective exploitation in high-velocity impact. The present article investigates the ballistic performance of twisted bilayer graphene (tBLG) nanostructures. We have employed molecular dynamics (MD) simulations, augmented further by coupling gaussian process-based machine learning, for the nanoscale characterization of various tBLG structures with varying relative rotation angle (RRA). Spherical diamond impactors (with a diameter of 25Å) are enforced with high initial velocity (Vi) in the range of 1 km/s to 6.5 km/s to observe the ballistic performance of tBLG nanostructures. The specific penetration energy (Ep*) of the impacted nanostructures and residual velocity (Vr) of the impactor are considered as the quantities of interest, wherein the effect of stochastic system parameters is computationally captured based on an efficient Gaussian process regression (GPR) based Monte Carlo simulation approach. A data-driven sensitivity analysis is carried out to quantify the relative importance of different critical system parameters. As an integral part of this study, we have deterministically investigated the resonant behaviour of graphene nanostructures, wherein the high-velocity impact is used as the initial actuation mechanism. The comprehensive dynamic investigation of bilayer graphene under the ballistic impact, as presented in this paper including the effect of twisting and random disorder for their prospective exploitation, would lead to the development of improved impact-resistant lightweight materials.

Activation of the Caprine ${\beta}$-Lactoglobulin Gene Promoter by Lactogenic Hormones in Cultured Mammary HC11 Cells

  • Kim, Jae-Min;Yu, Myeong-Hui;Kim, Gyeong-Jin
    • Animal cells and systems
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    • v.1 no.4
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    • pp.603-608
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    • 1997
  • Analysis of the 5'-regulatory sequence of the caprine ${\beta}$-lactoglobulin (BLG) gene promoter revealed that two different types of activation were mediated by discrete regions, from -740 to -470 and from -205 to 109, in cultured mammary HC11 cells. Activation mediated by the proximal region was observed regardless of cell growth status. Distal activation, however, was observed only after confluent growth of the cells and was enhanced by the lactogenic hormones. This activation was accompanied by appearance of binding activity of proteins to these regions in the mammary HC11 cells. The binding motifs were broadly distributed over the upstream regulatory sequence. Comparison of the binding regions and mutation analysis suggest that a binding motif homologous to the ${\gamma}$-interferon responsive element (${\gamma}$-IRE) is responsible for transcriptional activation by hormonal induction in the mammary HC11 cells. The multiple ${\gamma}$-IRE homologous motifs seem to play a significant role in enhancing mammary cell-specific activation of the caprine BLG gene.

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