• The Journal of the Korea institute of electronic communication sciences
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• v.10 no.3
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• pp.419-424
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• 2015

The era of IoT in which all objects are intelligent and are connected to the Internet has been started. In order to establish and activate an IoT eco system, open services platform is very important. In this paper, we developed a BLE sensor module as a component of the open service platform based on the IoT and the open source hardware Blutooth4.0. To verify the functionality and performance of the developed BLE sensor module was built to evaluate the performance of the test environment.

• Animal Bioscience
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• v.34 no.11
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• pp.1784-1793
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• 2021

Objective: An experiment was conducted to evaluate the effects of bamboo leaf extract (BLE) on the production performance, rumen fermentation parameters, and rumen bacterial communities of heat-stressed dairy cows. Methods: The experiment comprised a 14-day adaptation period and a 21-day experimental period and was conducted in a high-temperature and humidity environment (daily mean ambient temperature = 33.5℃±1.3℃; daily mean relative humidity = 64.9%±0.8%, daily mean temperature-humidity index = 86.2±0.4). Twelve Holstein dairy cows were randomly allocated into two groups. A total mixed ration supplemented with BLE at 0 (CON) and 1.3 g/kg dry matter (DM) were fed, respectively. Feed intake and milk yield were recorded daily. Milk samples were collected on 1, 11, and 21 d of the experimental period to analyze milk performance. Rumen fluid samples were collected on 21 d of the experimental period to analyze rumen fermentation parameters and rumen bacterial communities. Results: Compared with the control group, supplementation of BLE increased milk yield (p<0.01), milk fat yield (p = 0.04), 4% fat-corrected milk (p<0.01) and milk fat content (p<0.01); reduced somatic cell count (p<0.01). No differences in DM intake and milk protein or lactose content were observed between two groups. Supplementation of BLE also increased the rumen total volatile fatty acid (p<0.01), acetate (p<0.01), butyrate (p<0.01), and valerate (p = 0.05) concentrations. However, no significant effects were observed on rumen pH, ammonia nitrogen, propionate, acetate/propionate ratio, isobutyrate, or isovalerate. Furthermore, BLE increased the rumen bacterial abundance and the diversity of the rumen bacterial community. The BLE reduced the Firmicutes/Bacteroidetes abundance ratio and increased the abundances of Butyrivibrio_2 (p<0.01) and Ruminococcus_2 (p<0.01). Conclusion: The BLE supplementation at 1.3 g/kg DM could improve production performance and rumen fermentation in dairy cows during heat stress.

• Proceedings of the Korea Information Processing Society Conference
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• 2017.11a
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• pp.1155-1158
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• 2017

자동차 키의 발전이 커지면서 만드는데 있어 드는 비용이 점차 증가하고 있다. 그럼으로써 자동차 키를 분실 시 따른 개인적인 비용 손실이 증가하고 있다. 자동차 키의 분실을 방지하고자 자동차 키에 BLE 4.0의 동글을 부착하며 BLE 4.0의 RSSI을 활용한 위치 기반 서비스 시스템을 이요하고 자동차 키의 실시간 위치 확인 가능하도록 하며 우리의 눈을 통해 더 정확히 위치를 파악할 수 있도록 소리/진동 알림과 LED를 동글에 부착하여 시스템을 구축하였다.

• Journal of the Korea Convergence Society
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• v.13 no.4
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• pp.653-657
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• 2022

Oral disease causes a significant health and economic burden worldwide, significantly reducing people's quality of life. Dental caries, a representative oral disease, is caused by S. mutans. Oral pathogenic microorganisms contain lipopolysaccharide (LPS), which can cause an immune response and cause various oral diseases. The purpose of this study was to investigate the antioxidant and antibacterial effects of bamboo leaf extract (BLE) to control oral diseases. THP-1, oral fibroblasts, and S mutans culture medium were treated with bamboo leaf extract at different concentrations of 0-8% to conduct the experiment.. As a result, the antioxidant effect according to the BLE concentration was confirmed in mononuclear cell lines and oral fibroblasts. In addition, the antibacterial effect of S. mutans according to the BLE concentration was demonstrated. Therefore, BLE can be used for the prevention or treatment of oral diseases.

• Journal of Radiation Protection and Research
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• v.32 no.2
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• pp.59-64
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• 2007

We induced the activation of melanocytes in the epidermis of C57BL/6 mice by ultraviolet B (UVB) irradiation and observed the effect of bamboo (Phyllostachys nigra var. henenis Strapf) leaf extract (BLE) on the formation, and decrease of UVB-induced epidermal melanocytes. C57BL/6 mice were irradiated by $UVB\;80mJ/cm^2(0.5mW/sec)$ daily for 7 days, and BLE was intraperitoneally or topically applied pre-or post-irradiation. For the estimation of change of epidermal melanocytes, light microscopic observation with dihydroxyphenylalanine (DOPA) stain was performed. Split epidermal sheets prepared from the ear of untreated mice exhibited 11-16 $melanocytes/mm^2$, and one week after UV irradiation, the applied areas show an increased number of strongly DOPA-positive melanocytes with stout dendrites. But intraperitoneal or topical treatment with BLE before each irradiation interrupted UVB-induced pigmentation and resulted in a marked reduction in the number of epidermal melanocytes as compared to radiation control skin. The number and size of DOPA-positive epidermal melanocytes were also significantly decreased in intraperitoneally injected or topically applicated group after irradiation with BLE at 3rd and 6th weeks after irradiation. The results of present study indicate that BLE is likely to be useful as inhibitor of UVB-induced pigmentation and depigmenting agent.

• Nutrition Research and Practice
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• v.7 no.1
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• pp.9-14
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• 2013

Bamboo leaves (Phyllostachys pubescens Mazel ex J. Houz (Poacea)) have a long history of food and medical applications in Asia, including Japan and Korea. They have been used as a traditional medicine for centuries. We investigated the mechanism of anti-inflammatory activity of a bamboo leaf extract (BLE) on tumor necrosis factor-alpha (TNF-${\alpha}$)-induced monocyte adhesion in human umbilical vein endothelial cells (HUVECs). Exposure of HUVECs to BLE did not inhibit cell viability or cause morphological changes at concentrations ranging from 1 ${\mu}g/ml$ to 1 mg/ml. Treatment with 0.1 mg/ml BLE caused 63% inhibition of monocyte adhesion in TNF-${\alpha}$-activated HUVECs, which was associated with 38.4% suppression of vascular cell adhesion molecule-1 expression. Furthermore, TNF-${\alpha}$-induced reactive oxygen species generation was decreased to 47.9% in BLE treated TNF-${\alpha}$-activated HUVECs. BLE (0.05 mg/ml) also caused about 50% inhibition of interleukin-6 secretion from lipopolysaccharide-stimulated monocyte. The results indicate that BLE may be clinically useful as an anti-inflammatory or anti-oxidant for human cardiovascular disease including atherosclerosis.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.4
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• pp.925-932
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• 2015

In this paper, by utilizing the iBeacon is BLE (BlueTooth Low Energy) protocol devices that are supported by over the Bluetooth 4.0, and have implemented a system to improve the accuracy in the system for measuring the position of the user. After measuring through the system according to the state of the iBeacon, the interference factors are analyzed through analysis of the collected data, and applying the extended Kalman filter for calibration. Compared with the data after applying a filter with existing data, it was confirmed an increase in accuracy. Improvement techniques for providing the less complexity to the actual implementation, is effective in improving the accuracy of vulnerable services basic iBeacon.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.352-354
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• 2016

Recent with the progress of smart devices, there is an increasing demand for indoor location-based services. For this reason, research on indoor positioning system using a iBeacon techniques added to BLE(Bluetooth Low Energy) specifications of Bluetooth4.0 has been actively. However, RSSI signal used for the measurement of the distance between the iBeacon and the receiving terminal has the problems of inaccurate distance measurement to environmental factors such as obstacles. In this paper, we propose an implemented indoor positioning technique to use filtering technology enhance the reliability of the RSSI signal and the broadcasting signal of the terminal access point function.

• Proceedings of the Korea Contents Association Conference
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• 2015.05a
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• pp.37-38
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• 2015

최근 안드로이드 4.0 이상 버전에서 저전력 블루투스(Bluetooth Low Energy) 기능이 지원되면서, 다양한 응용사례가 나타나고 있다. 이러한 BLE 프로토콜을 활용하는 Sensor-Tag IoT 센서노드를 활용하면 스마트홈, 웨어러블, 스마트카, 생활밀착 서비스, 스마트에너지, 산업 및 환경분야에서 다양한 스마트폰 앱을 개발할 수 있다. 또한, BLE-스택(Stack)TM 소프트웨어를 사용하면, 라이센서 걱정없이 펌웨어 소스코드의 개발 및 업데이트가 가능하다. 따라서, 다양한 센서가 장착된 IoT Sensor 노드를 통하여, 습도/온도/가속도/지자기/자이로 등의 데이터를 수집하여 활용할 수 있다. 이에 본 논문에서는 "저전력 센서 노드를 사용한 IoT 서비스 설계 프레임워크"를 제안한다.

• Journal of Korea Society of Digital Industry and Information Management
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• v.18 no.4
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• pp.47-54
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• 2022

In this paper, MEMS embedded system design implemented the sensor events via analyzing the characteristics that dynamically happened to an abnormal status in power IoT environments in order to guarantee a maintainable operation. We used three kinds of tools in this paper, at first Bluetooth Low Energy (BLE) technology which is a suitable protocol that provides a low data rate, low power consumption, and low-cost sensor applications. Secondly LSM6DSOX, a system-in-module containing a 3-axis digital accelerometer and gyroscope with low-power features for optimal motion. Thirdly BM1422AGMV Digital Magnetometer IC, a 3-axis magnetic sensor with an I2C interface and a magnetic measurable range of ±120 uT, which incorporates magneto-impedance elements to detect the magnetic field when the current flowed in the power devices. The proposed MEMS system was developed based on an nRF5340 System on Chip (SoC), previously compared to the standalone embedded system without bluetooth technology via mobile App. And also, MEMS embedded system with BLE 5.0 technology broadcasted the MEMS system status to Android mobile server. The experiment results enhanced the performance of MEMS system design by combination of sensors, BLE technology and mobile application.