• 대한한의학회지
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• 제25권4호
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• pp.220-225
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• 2004

Objective : Electroacupuncture is one of the primary remedies in oriental medicine. Elecroacupuncture was applied on a nocturia patient. Improvement of the symptoms was experienced. This case is reported in order to derive further studies evaluating the effectiveness of this treatment. Methods : Electroacupuncture on the Ciliao acupoint(BL32) was performed twice daily for 1 week. Results : After about 1 week of electroacupuncture on the Ciliao acupoint(BL32), there was a remarkable decrease of nocturia frequency. Conclusion: We present the case of a mao with an overactive bladder who had several stokes as well as hypertension. Electroacupuncture treatment performed on the Ciliao acupoint(BL32) remarkably improved nocturia.

• 동의신경정신과학회지
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• 제15권2호
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• pp.37-44
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• 2004

Objectives : The purpose of this report is a study on the correlation between parasympathetic nerve system and Back-shu points. Methods : We have studied about the correlation between anatomical distribution of parasympathetic nerve system and that of Back-shu points. Back-shu points are located on the back area as the acupoints of Bladder Meridian(BL), doing its own organic physical and pathological working and directly connected with its own organ. Results and Conclusions : 1. It is suggested that Back-shu points has correlation with parasympathetic nerve system could be Pangguanshu(BL28), Zhonglushu(BL29), Baihuanshu(BL30), Ciliao(BL32), Zhongliao(BL33), Xialiao(BL34), Shangliao(BL31), Xiaochangshu(BL27), Baohuang,(BL53) Zhibian(BL54) etc. 2. We proved acupuncture treatment on the nearby spinal area could be one of the method that could stimulate parasympathetic nerve system. 3. The symptom of parasympathetic nerve system's disorder is similar to Back-shu points' chief efficacy a lot. And we proved the Back-shu points which has relation with parasympathetic nerve system as distribution of nerve system are only located at sacral area.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제17권1호
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• pp.23-32
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• 2011

Recently, with the advent of high risk infectious agent such as the Ebola virus, SARS, special research facilities dealing with such dangerous pathogenic are drawing attention gradually. Especially, this kind of facilities can be called BL4(Biosafety Level 4) facility. At the moment, Korean government is going to construct BL4 institute in order to handle efficiently such kind of pathogen. However, there are no proper design guidelines for BL4 facility. This paper proposes circulation system of BL4 facility on the basis of analysis of existing BL4 guidelines of Canada, and Korean BL3 facilities. The outcomes of this study are as follows. At first, functional areas of BL4 facilities have been divided into three categories according to the hazard level ; dangerous area, transitional area, and ordinary area. Secondly, circulation system of BL4 facility has been explored as a form of diagram according to the circulating subjects. These include human, laboratory animals, hazardous pathogen, equipments and cloth. This study has some limitations in that it lacks empirical evidences and concrete SOPs(Standard Operating Procedure). Despite of some weaknesses, it is expected to give some preliminary guidelines for the design of circulation system in BL4 facilities.

• 한국정보전자통신기술학회논문지
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• 제16권6호
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• pp.509-518
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• 2023

본 논문에서는 아날로그 회로 트리밍과 Calibration 등에 필요한 4Kb Poly-Fuse OTP IP를 설계하였다. NMOS Select 트랜지스터와 Poly-Fuse 링크로 구성된 Poly-Fuse OTP 셀의 BL 저항을 줄이기 위해 BL은 Metal 2와 Metal 3를 stack하였다. 그리고 BL 라우팅 저항을 줄이기 위해 4Kb 셀은 64행 × 32열 Sub-block 셀 어레이 2개로 나뉘었으며, BL 구동회로는 Top과 Bottom으로 나누어진 2Kb Sub-block 셀 어레이의 가운데에 위치하고 있다. 한편 본 논문에서는 1 Select 트랜지스터에 1 Poly-Fuse 링크를 사용하는 OTP 셀에 맞게 코어회로를 제안하였다. 그리고 OTP IP 개발 초기 단계에서 프로그램되지 않은 Poly-Fuse의 저항이 5kΩ까지 나올수 있는 경우까지를 고려한 데이터 센싱 회로를 제안하였다. 또한 Read 모드에서 프로그램되지 않은 Poly-Fuse 링크를 통해 흐르는 전류를 138㎂ 이하로 제한하였다. DB HiTek 90nm CMOS 공정으로 설계된 Poly-Fuse OTP 셀 사이즈는 11.43㎛ × 2.88㎛ (=32.9184㎛2)이고, 4Kb Poly-Fuse OTP IP 사이즈는 432.442㎛ × 524.6㎛ (=0.227mm²)이다.

• Korean Journal of Acupuncture
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• 제29권4호
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• pp.519-536
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• 2012

Objectives : The purpose of this study is to figure out which acupoints are selected to treat low back pain and attempt to analyze the effectiveness of those acupoints in current clinical trials. Methods : We searched the three electronic databases(PUBMED, RISS, KISS) and manually checked related Korean journals and reference lists up to April 2012. We included randomized controlled trials, clinical controlled trials, and case reports/series using needle type acupuncture( manual acupuncture, electronic acupuncture) to treat low back pain in English and Korean. We investigated the frequency of selected acupoints, change of visual analogue scale of low back pain and statistical significance in each study among trials. Results : We included 37 articles(Domestic 17, International 20) 53 studies(Domestic 28, International 25) in this study. The most frequently adopted acupoints were BL23, BL24, BL25, GB30, BL26, BL60, BL32, BL40, KI3, GV3, ST36 in domestic studies and BL23, BL25, BL40, BL60, GB30, GB34, BL32, BL26 in international studies. There were differential effectiveness of acupoints between domestic and the international studies using statistical significance of visual analog scale for low back pain. Conclusions : These results suggest that both proximal and distal acupoints based on meridian theory were used in clinical trials to treat low back pain. It would be helpful to provide clinical guideline, evaluate the results of clinical trials appropriately, and reveal the effectiveness of acupoints.

• Korean Journal of Acupuncture
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• 제30권2호
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• pp.135-142
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• 2013

목적 : 본 연구는 노년층의 여성에게 신맥(BL62), 조해(KI6)혈에 대한 저주파자극이 뇌파에 어떠한 영향을 미치는지 알아보고 뇌 기능을 개선하는데 비화학적이고 비침습적인 자극 방법의 후보로써 가능성을 탐구해보고자 실시된 탐색적 연구이다. 방법 : 31명의 건강한 여성 피험자(평균연령, 54.5세)를 대상으로 이중맹검 무작위배정 임상연구가 12세션동안 실시되었다. 시험군에서는 감지할 수 없는 최대의 저주파자극이 실시되었으며(평균전류량, $0.04{\mu}A$), 대조군에서는 거짓자극이 실시되었다. 결과분석을 위해 12세션을 전후로 배경뇌파가 측정되었다. 결과 : 12세션의 자극이 실시된 후 대조군에 비해 실험군의 알파파 상대값은 11채널에서 유의한 증가를 보였으며(p<0.05), 감마파의 상대값은 7채널에서, 세타파의 상대값은 10채널에서 유의한 감소를 보였다. 결론 : 발목관절에 있는 신맥(BL62), 조해(KI6)혈에 대한 저주파 자극은 노년의 여성의 뇌에 베타, 세타, 감마파의 감소를 일으키는 반면 알파파를 선택적으로 증가시켜 뇌를 안정시키는 효과가 있는 것으로 보인다. 이러한 결과는 저주파자극이 향후 스트레스와 관련된 인지 문제를 치료하는 비침습적이고 비화학적인 도구로써의 가능성을 제공할 수 있을 것으로 보이며, 그 기전에 대한 추가적 연구가 필요할 것으로 보인다.

• Journal of Acupuncture Research
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• 제23권4호
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• pp.101-113
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• 2006

Objectives : This study was designed to evaluate the effect of electroacupuncture at ciliao(BL32) on voiding pattern and uroflowmetry of patients with functional voiding disease. Methods Subjects were voluntarily recruited by newspaper·s and internet. All the subjects were confirmed as International Prostatism Symptom Score(IPSS), uroflowmetry, voiding diary, symptom. The acupuncture therapy was performed 3 times a week for 3 weeks by oriental medical doctor at hospital. Acupuncture points were BL32. The patient's symptoms were assessed before and after 3 weeks treatments by IPSS. Uroflowmetry for 5minutes and voiding diary for 48 hours was measured before and after 3 weeks treatments. Results : The results were as follows; 1. After 3 weeks compared to the pre-treatment, IPSS(QOL) scores were significantly unproved. 2. After 3 weeks compared to the pre-treatment, mean voiding volume, min voiding volume and mean voiding time on voiding daiary was significantly improved. 3. After 3 weeks compared to the pre-treatment, max flow velocity and mean flow velocity on uroflowmetry in spite of increase of voiding volume show a statistically significant difference. 4. Acupunctue had hardly some side effect compared to operation and medicines and was economical. Conclusion : This study suggests that acupuncture treatments can be applicable to improve symptoms in the patients with functional voiding disease. Further study on the acupuncture and other acupoints in the patients with functional voiding disease is recommended.

• Fisheries and Aquatic Sciences
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• 제19권4호
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• pp.20.1-20.12
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• 2016

The osteological development in Sebastes koreanus is described and illustrated on the basis of 32 larvae [6.11-11.10 mm body length (BL)] and a single juvenile (18.60 mm BL) collected from the Yellow Sea. The first-ossified skeletal elements, which are related to feeding, swimming, and respiration, appear in larvae of 6.27 mm BL; these include the jaw bones, palatine, opercular, hyoid arch, and pectoral girdle. All skeletal elements are fully ossified in the juvenile observed in the study. Ossification of the neurocranium started in the frontal, pterotic, and parietal regions at 6.27 mm BL, and then in the parasphenoid and basioccipital regions at 8.17 mm BL. The vertebrae had started to ossify at ~7.17 mm BL, and their ossification was nearly complete at 11.10 mm BL. In the juvenile, although ossification of the pectoral girdle was fully complete, the fusion of the scapula and uppermost radial had not yet occurred. Thus, the scapula and uppermost radial fuse during or after the juvenile stage. The five hypurals in the caudal skeleton were also fused to form three hypural elements. The osteological results are discussed from a functional viewpoint and in terms of the comparative osteological development in related species.

• 한국정보전자통신기술학회논문지
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• 제17권4호
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• pp.266-274
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• 2024

본 논문에서는 아날로그 회로 트리밍과 보정 (calibration) 등에 필요한 데이터를 저장하는 비휘발성 메모리인 저면적 32bit PF (Poly-Fuse) OTP IP를 설계하였다. 한 개의 선택 트랜지스터에 2개의 PF를 사용하여 하나의 OTP 셀을 구성하므로 2 비트의 데이터를 프로그램할 수 있는 1셀-2비트의 multibit PF OTP 셀을 제안하였다. 제안된 1셀-2비트 PF OTP 셀의 bitcell 사이즈는 12.69㎛ × 3.48㎛ (=44.161㎛2)의 1/2로 기존 PF OTP 셀의 bitcell 사이즈에 비해 셀 면적을 33% 줄였다. 한편 본 논문에서는 제안된 multbit 셀의 동작에 맞도록 1행 × 32열 셀 어레이 회로와 코어 회로 (WL 구동회로, BL 구동회로, BL 스위치 회로와 DL sense amplifier 회로)를 새롭게 제안하였다. 제안된 multibit 셀을 사용한 32bit OTP IP의 레이아웃 사이즈는 238.47㎛ × 156.52㎛ (=0.0373㎛2)으로 기존 single bitcell을 이용한 32bit PF OTP IP 사이즈인 386.87㎛ × 144.87㎛ (=0.056㎛2)에 비해 면적을 33% 정도 줄였다. 10년의 data retention 시간을 고려하여 설계된 32bit PF OTP IP는 detection read 모드와 read 모드에 서 프로그램된 PF의 최소 센싱 저항은 테스트 칩의 post-layout 모의실험 결과 각각 10.5㏀과 5.3㏀으로 설계하였다.

• 한국식품영양과학회지
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• 제18권1호
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• pp.109-114
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• 1989

쌀보리가루에서 결합지질을 방법을 달리하여 추출하고 이들을 중성지질, 당지질, 인지질등으로 분획하였으며 다시 이 분획된 성분들의 구성 지질들을 분별 정량한 다음 각 지질들의 지방산 조석을 분석하였다. Water saturated butanol ($25^{\circ}C$, WSB-LT) 추출 결합지질에서는 중성, 당, 인지질의 함량이 각각 35.5%, 32.4%, 32.1% 그리고 WSB($95^{\circ}C$, WSB-HT)추출 결합지질에서는 인지질의 함량이 50.6%로 가장 많았다. 중성지질 성분중 대부분을 차지하는 성분중 대부분을 차지하는 것은 triglyceride$(66{\sim}82.9%)$이고 그외 free fatty acid, free sterol, diglycericte, esterified sterol 등이 분별정량되었으며, 당지질 성분중에서는 digalactosyl diglycerides, cerebrosides, steryl glycosides, monogalactosyl diglycerides등이 주요 구성성분이였고 이중 digalactosyl diglyceride$(40.2{\sim}44.8%)$의 함량이 가장 많았다. 인지질의 경우에는 lysophosphatidyl choline $(20.3{\sim}34.4%)$, phosphatidyl choline & phsphatidyl serine$(18.6{\sim}22.5%)$, phosphatidyl ethanolamine$(18.4{\sim}28.2%)$, dtphosphatidyl glycerols $(10.5{\sim}16.9%)$등으로 그 성분이 구성되어 있었으며, 대체로 구성성분은 추출방법에 따른 차이를 발견할 수 있었으나 인지질외에는 그 차이가 심하지 않았다. 또한 쌀보리에서 추출한 결합지질의 주요 지방산은 linoleic acid와 palmitic acid로서 추출방법에 따른 지방산 조성의 큰 차이점은 없었으며, 특히 중성지질에서는 palmitic acid 함량이 $34.3{\sim}38.2%$, linoleic acid 함량이 $44.2{\sim}48.8%$였다.