• Title/Summary/Keyword: BK21사업

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The hardening effect by ice-quenching after oxidation of a Pd-Ag-Sn-Au metal-ceramic alloy during porcelain firing simulation (금속-세라믹용 Pd-Ag-Sn-Au계 합금의 모의소성 시 산화처리 후 급랭에 의한 경화 효과)

  • Shin, Hye-Jeong;Kim, Min-Jung;Kwon, Yong-Hoon;Kim, Hyung-Il;Seol, Hyo-Joung
    • Korean Journal of Dental Materials
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    • v.44 no.3
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    • pp.197-206
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    • 2017
  • The hardening effect by ice-quenching after oxidation of a Pd-Ag-Sn-Au metal-ceramic alloy during porcelain firing simulation was investigated by means of hardness test, field emission scanning electron microscopic observations, and X-ray diffraction analysis. The hardness decreased by ice-quenching after oxidation, which was induced by the homogenization of the ice-quenched specimen. The decreased hardness by ice-quenching after oxidation was recovered from the wash stage which was the first stage of the remaining firing process for bonding porcelain. After wash stage, the hardness of the ice-quenched specimens decreased during the subsequent porcelain firing process. But the final hardness of the ice-quenched specimens after oxidation was higher than that of the specimens cooled at stage 0 after oxidation. The increase in hardness of the specimens during the first firing process was caused by the lattice strains generated at the interface between the face-centered cubic Pd-Ag-rich matrix and the face-centered tetragonal Pd3(Sn, Ga, In) precipitate. The decrease in hardness of the specimens during the remaining firing process was caused by the microstructural coarsening.

Predicting the influent properties in an infiltration trench through deep learning analysis (딥러닝 분석을 통한 침투도랑 내 유입수 성상 예측분석)

  • Jeon, Minsu;Choi, Hyeseon;Geronimo, Franz Kevin;Heidi, Guerra;Jett, Reyes Nash;Kim, Leehyung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.363-363
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    • 2022
  • LID 시설에 대한 모니터링은 인력을 활용한 실강우 모니터링을 진행하고 있으나 LID 시설은 소규모 분산형시설로서 인력을 동원한 식생고사, 강우시 모니터링, 현장답사 등 꾸준한 시설확인에 한계가 있으며, LID 시설을 조성한 이후 적정한 유지관리 방법(주기, 빈도, 항목 등)을 인지하지 못하여 막힘현상, 효율저하, 식물고사 등의 문제가 발생한다. 따라서 본연구에서는 딥러닝 분석을 활용하여 강우시 강우모니터링 자료와 LID 시설 내 센서를 통해 측정된 자료를 통해 침투도랑 내 유입수 성상에 대한 예측분석을 수행하였다. 심지 내 LID 시설에 유입되는 오염물질을 예측을 위한 딥러닝 분석을 위해 과거 실강우시 모니터링 자료(TSS, COD, TN, TP)와 대기센서(대기습도, 대기온도, 강수량, 미세먼지) 데이터를 활용하여 딥러닝 모델에 대한 적용가능성 평가를 수행하였다. 측정항목에 대한 상관성 분석을 수행하였으며, 딥러닝 모델은 Tenser Flow를 이용하여 DNN(Deep Neural Network)모델을 활용하여 분석하였다. DNN 모델에 대한 MSE값은 0.31로 분석되었으며, TSS에 대한 평균 50.6mg/L로 분석되었으며, COD 평균 98.7 mg/L로 나타났다. TN의 평균 2.21 mg/L로 분석되었으며, TP 평균 0.67 mg/L로 나타났다. 상관계수분석결과 TSS는 0.53로 분석되었으며, TN과 TP의 상관계수는 0.10, 0.56으로 나타났다. COD의 상관계수는 0.63으로 TSS와 COD, TP에 대한 예측이 된 것으로 분석되었다. 딥러닝을 통한 LID 시설 내 농도변화 예측시 강우시 센서데이터 값은 조밀해야하며 오염물질 농도와 상관성이 높은 항목들에 대해 계측과 실강우 모니터링 자료를 축적하여 미래에 대한 활용성을 높여야 한다.

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Data Envelopment Analysis and Logistic Model for BRAIN KOREA 21 (분류모형과 DEA를 이용한 두뇌한국(BK) 21 사업단 효율성 분석)

  • Sohn, So-Young;Joo, Yong-Gyu
    • IE interfaces
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    • v.17 no.3
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    • pp.249-260
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    • 2004
  • The objective of this study is to measure and to predict the efficiency of participating groups of BK 21 by using DEA. DEA is a methodology to measure and to evaluate the relative efficiency of a homogeneous set of decision-making units (DMUs) in a process which uses multiple inputs to produce multiple outputs. In order to reflect the effect of the environmental factors of BK 21, we consider not only a general DEA model but also a logistic model for DEA. As a result, location of participating groups of BK 21 turns out to be significant. Our proposed approach can predict the efficiency of a new BK 21 group with given environmental factors. It is expected that these models can give a feedback for effective management of BK 21.

Antibacterial effect of Zingiberaceae extracts mediated photodynamic therapy on Streptococcus mutans (Streptococcus mutans에 대한 생강과 천연추출물의 광역학 항균효과)

  • Hwang, Hye-Rim;Kang, Si-Mook;Lee, Eun-song;Kim, Baek-Il
    • The Journal of the Korean dental association
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    • v.57 no.10
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    • pp.560-568
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    • 2019
  • Purpose: This study evaluated the antibacterial effects of curcuma, ginger, and finger root extracts in water-soluble powder on planktonic Streptococcus mutans(S.mutans), which is known to cause dental caries, in order to confirm whether these extracts could perform as photosensitizers for the effects of photodynamic therapy (PDT). Methods: This study used the strain of streptococcus mutans ATCC 25175 distributed by the Korean Collection for Type Cultures of the Korea Research Institute of Bioscience & Biotechnology. Commercial edible curcuma, ginger and finger root were used as the natural extracts for the use of photosensitizer. To extract organic solvent, 3 g of each powder was mixed in $30m{\ell}$ of dimethyl sulfoxide (DMSO, VWR, Germany) before extraction. $1.8m{\ell}$ of the photosensitizer solution, manufactured in the concentrations of 5, 0.5, and $0.05mg/m{\ell}$, was mixed with $0.2m{\ell}$ of the S. mutans culture medium that had been cultured for 2 days. To induce the photodynamic reaction, Qraycam (AIOBIO, Seoul, Korea) equipped with 405 nm LED was used to expose light for 5 minutes to irradiate 59 nW energy for 300 seconds. Results: Compared with the case with no light, a higher photodynamic therapeutic effect was confirmed with $0.05mg/m{\ell}$ curcuma powder extract, the concentration of $0.5mg/m{\ell}$ and LED light of 405 nm wavelength (p=0.000, p=0.003). $0.05mg/m{\ell}$ of curcuma powder extract and the concentration of $0.5mg/m{\ell}$ showed 100% antibacterial effect when exposed to light, whereas the concentration of $5mg/m{\ell}$ showed 11.95% antibacterial effect. When exposed to light, $0.05mg/m{\ell}$ of ginger powder extract showed an antibacterial effect which didn't statistically decrease. The concentrations of $0.5mg/m{\ell}$ and $5mg/m{\ell}$ did not show any antibacterial effects. As a result of examining any photodynamic therapeutic effects of finger root powder extract on S. mutans, no statistically significant effect was found. Conclusion: The curcuma powder extract is expected to perform as a photosensitizer. Even though belonging to the same ginger family, ginger powder and finger root powder seem difficult to perform as photosensitizer.

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Classification of maturation of bacterial dental deposits using differences in fluorescence intensity (형광 차이를 이용한 세균성 치아 침착물의 성숙도 구별)

  • Cho, Mu-Yeol;Lee, Eun-Song;de Jong, Elbert de Josselin;Yoon, Hong-Chul;Kim, Baek-Il
    • The Journal of the Korean dental association
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    • v.57 no.4
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    • pp.213-220
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    • 2019
  • Purpose: The aim of this study was to evaluate the red fluorescence characteristics of bacterial dental deposits assessed by quantitative light-induced fluorescence (QLF) technology and confirm whether the red fluorescence can distinguish and evaluate quantitatively accumulation of bacterial dental deposits. Methods: This retrospective cross-sectional study used QLF images captured at a dental clinic from January to December 2016. In each QLF image, a skilled examiner selected one region where the presence of deposits was suspected. Then, the regions were classified into three groups of not detectable deposits(ND), half detectable deposits (HD), and full detectable deposits (FD) by two examiners according to classification criteria. Only those images where the regions of bacterial dental deposits were classified identically by all examiners were used for analysis. The mean red fluorescence intensity (RFI) was defined as the mean value of R/G for all pixels in the regions. The RFI was compared between groups using Welch's ANOVA test, and the Spearman correlation was calculated to assess the association between RFI and accumulation of deposits. Results: In this study, 351 images among the collected images of 605 subjects were finally selected. The mean age of subjects was about 44 years. The R/G values of the ND, HD and FD were 0.73, 1.26 and 1.83 respectively. There were significant differences between all groups (p<0.001), and strong positive correlation was identified between the R/G value and the accumulation of deposits (r = 0.90, p<0.001). Conclusion: The intensity of red fluorescence as observed in the QLF images correlated well with the accumulation maturation of the deposits, which indicates that the QLF technology can be used to evaluate the status of oral hygiene.

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Water Extract of Fermented New Korean Medicinal Mixture (F-MAPC) Controls Intracellula Adipogenesis and Glut-4 dependent Glucose Uptake in 3T3-L1 Adipocytes and L6 Myoblasts (세포 내 지방생성과 Glut-4 의존성 포도당 운반에 미치는 발효복합한약 물추출물(F-MAPC)의 영향)

  • Jeon, Seo Young;Park, Ji Young;Kim, Sung Ok;Lee, Eun Sil;Koo, Jin Suk;Kim, Mi Ryeo
    • The Korea Journal of Herbology
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    • v.29 no.1
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    • pp.45-52
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    • 2014
  • Objectives : The aim of this study was to investigate the effects water extract of fermented new korean medicinal mixture, combinations of Mori Folium, Adenophorae Radix, Phllostachyos Folium and Citri Pericarpium (F-MAPC), on adipocyte differentiation, adipogenesis and glucose uptake using undiffernentiated 3T3-L1 adipocytes and L6 myoblasts. Methods : Each herb and those mixture were respectively fermented and then extracted with water. We carried on MTT assay for check-up on cell toxicity, Oil Red O staining for determination of cell differentiation and intracelluar adipogenesis. Western blot analysis for measurement of pAMPK and pACC, $C/EBP{\alpha}$, $PPAR{\gamma}$ and Glut-4 protein expressions were performed. Results : F-MAPC showed significant inhibitory activity on adipocyte differentiation in 3T3-L1 preadipocytes without affecting cell toxicity as assessed by measuring fat accumulation, and this effect was 2 fold higher in 0.2 mg/ml F-MAPC than that of the same dose of each fermented herbal extract alone. In addition, these effects were associated with modulation of adipogenic transcription factors, such as $C/EBP{\alpha}$, $PPAR{\gamma}$, as well as stimulated phosphorylations of AMPK and ACC. Translocation of Glut-4 was significantly increased by 10.2% in L6 cells treated with 0.2 mg/ml F-MAPC compared with that of control. Conclusions : These results demonstrate that F-MAPC may be an ideal candidate for therapy of obesity and diabetes by disturbing the differentiation into adipocytes, as well as the inducement of intramuscular glucose uptake from blood.

Perceived Social Support of Family Caregivers for People with Dementia: Concept Analysis (치매 환자의 가족 돌봄 제공자가 인식하는 사회적지지: 개념 분석)

  • Kim, Aeri;Kim, Jeongyeon;Woo, Kyungmi
    • Research in Community and Public Health Nursing
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    • v.32 no.4
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    • pp.540-554
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    • 2021
  • Purpose: Most of the currently used concepts and measurements of social support have been relevant for general population. The main purpose of this study is to conduct the concept analysis of perceived social support(PSS) of family caregivers for people with dementia. Methods: This study adopted the Walker and Avant concept analysis methodology. Results: Findings from this concept analysis suggested four defining attributes of PSS of family caregivers for people with dementia: 1) PSS is help or assistance that family caregivers perceive as available when needed; 2) PSS is offered through socio-ecological structure; 3) PSS has a specific function to meet the needs of family caregivers; and 4) PSS includes quality aspects where family caregivers choose, use, or evaluate it. Borrowing from the socio-ecological model, this study proposed the structural aspects of PSS. This study also identified functional aspects of PSS, such as emotional support, informational support, appraisal support, and practical support. Finally, this study assessed quality aspects of PSS, such as satisfaction, timeliness, usefulness, accessibility, and coordination. Conclusion: Focusing on family caregivers for people with dementia, we proposed a new model of PSS. The present study helped refine and clarify the concept of PSS of family caregivers for people with dementia. The results of this study may also contribute to promoting the development of more effective instruments for the concept.

Increased Expression of CTGF in Periodontitis Tissue and Its Role for Enhanced Mature Osteoclast Survival (치주염 조직에서 발현이 증가하는 CTGF에 의한 파골세포 생존 증가)

  • Han, Hye-Yeon;Park, Jong-Cheol;Ryu, Mi Heon;Bae, Moon-Kyoung;Kim, Hyung Joon
    • The Korean Journal of Oral and Maxillofacial Pathology
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    • v.41 no.4
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    • pp.155-162
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    • 2017
  • Connective tissue growth factor (CTGF, CCN2) is one of the multi-functional secreted proteins which belong to CCN family of cysteine-rich growth factors. CTGF is known to have pivotal roles in embryonic endochondral ossification but its role in relevance to periodontitis is never been determined. To identify new molecular mediators associated with periodontitis-induced bone resorption, we have analyzed publicly available GEO database and found the markedly augmented CTGF mRNA expression in periodontitis gingival tissues. The existence of CTGF significantly enhanced mature osteoclasts survival which accompanied by reduction in TUNEL-positive nuclei and PARP cleavage. These results may provide another line of evidence the CTGF mediated prolonged osteoclast survival and subsequent increased bone resorption in the periodontitis patients.