Water Extract of Fermented New Korean Medicinal Mixture (F-MAPC) Controls Intracellula Adipogenesis and Glut-4 dependent Glucose Uptake in 3T3-L1 Adipocytes and L6 Myoblasts
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Jeon, Seo Young
(Team for Scientification of Korean Medical Intervention (BK21 Plus) & Dept. of Herbal Pharmacology, Coll. of Oriental Medicine, Daegu Haany Univ.)
Park, Ji Young (Team for Scientification of Korean Medical Intervention (BK21 Plus) & Dept. of Herbal Pharmacology, Coll. of Oriental Medicine, Daegu Haany Univ.) Kim, Sung Ok (Team for Scientification of Korean Medical Intervention (BK21 Plus) & Dept. of Herbal Pharmacology, Coll. of Oriental Medicine, Daegu Haany Univ.) Lee, Eun Sil (Ido Co. Ltd.) Koo, Jin Suk (Dept. of Medicinal Plant Resources, Coll. of Natural Sciences, Andong National Univ.) Kim, Mi Ryeo (Team for Scientification of Korean Medical Intervention (BK21 Plus) & Dept. of Herbal Pharmacology, Coll. of Oriental Medicine, Daegu Haany Univ.) |
1 | Barness LA, Opitz JM, Barness EG. Obesity: genetic, molecular, and environmental aspects. Am J Med Genet A. 2007 ; 143 : 3016-34. |
2 | Jo HG, Kim BT. Causes and treatment of obesity and literature review on stage. Korea Inst Sci Technol Inform. 1992 ; 1 : 61-71. |
3 | Chae US. Haneuihakgaeron. Seoul : Daeseoungmunhwasa. 1997 : 294. |
4 | Jung YJ, Han Do, Choi BH, Park C, Lee HJ, Kim SH, Hahm DH. Effect of fermented herbal extracts, HP-1 on enzyme activities and gene expressions related to alcohol metabolism in ethanol-loaded rats. Korean J Oriental Physiol Pathol. 2007 ; 21 : 387-91. 과학기술학회마을 |
5 | Hwang MY, Kim YH. Motion for consideration of obesity pathophysiology(I). J Jeahan Oriental Med Acad. 1984 ; 8 : 77-83. |
6 | Park YK, Yoo HH, Beak SH, Lee SH, Kim CM, Lee KS, Park MK, Park JH. Quality control of Adenophorae Radix. Kor J Pharmacogn. 2003 ; 34 : 10-3. 과학기술학회마을 |
7 | Lee SE, Lee EH, Lee TJ, Kim SW, Kim BH. Anti-obesity effect and action mechanism of Adenophora Triphylla Root ethanol extract in C57BL/6 obese mice fed high fat diet. Biosci Biotechnol Biochem. 2013 ; 77 : 544-50. DOI ScienceOn |
8 | Koide CL, Collier AC, Berry MJ, Panee J. The effect of bamboo extract on hepatic biotransforming enzymes -findings from an obese-diabetic mouse model. J Ethnopharmacol. 2011 ; 133 : 37-5. DOI ScienceOn |
9 | Yook CS. Encyclopedia of pharmacognosy. Seoul : Kyoung Won Publishing Company. 1997 : 273-4, 282, 305. |
10 | Yang G, Lee J, Jung ED, Ham I, Choi HY. Lipid lowering activity of Citri Unshii Pericarpium in hyperlipemic rats. Immunopharmacol Immunotoxicol. 2008 ; 30 : 783-91. DOI ScienceOn |
11 | Vamecq J, Latruffe N. Medical significance of peroxisome proliferator-activated receptors. The Lancet. 1999 ; 354 : 141-8. DOI ScienceOn |
12 | Rangwala SM, Lazar MA. Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. Trends Pharmacol Sci. 2004 ; 25 : 331-6. DOI ScienceOn |
13 | Ntambi JM, Kim YC. Adipocyte differentiation and gene expression. J Nutr. 2000 ; 130 : 3122-6. DOI |
14 | Hardie DG. The AMP-activated protein kinase pathway new players upstream and downstream. J Cell Sci. 2004 ; 117 : 5479-87. DOI ScienceOn |
15 | Nam KC, Kim MS, Lee WJ, Jang PG, Han SM, Koh EH, Park JY, Lee KU. Hypothalamic AMPK activity in diabetic rats. J Kor Diabetes Assoc. 2004 ; 28 : 468-77. |
16 | Ishikura S, Bilan PJ, Klip A. Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells. Biochem Biophys Res Commun. 2007 ; 353 : 1074-9. DOI ScienceOn |
17 | Rowland AF, Fazakerley DJ, James DE. Mapping insulin/GLUT4 circuitry. Traffic. 2011 ; 12 : 672-81. DOI ScienceOn |
18 | Bell GL, Burant CF, Takeda J, Gould GW. Structure and function of mammalian facilitative sugar transpor ters. J Biol Chem. 1993 ; 268 : 161-4. |
19 | Korea Centers for Disease Control and Prevention. 2009 Korea national health and nutrition and examination survey. Ministry of Health and Welfare. 2010. |
20 | Grundy SM. Multifactorial causation of obesity: implications for prevention. Am J Clin Nutr. 1998 ; 67 : 563-72. DOI |
21 | Lew EA. Mortality and weight: insured lives and the american cancer society studies. Ann Intern Med. 1985 ; 103 : 1024-9. DOI ScienceOn |
22 | Spiegelman BM, Flier JS. Adipogenesis and obesity: rounding out the big picture. Cell. 1996 ; 87 : 377-89. DOI ScienceOn |
23 | Rosen ED, Spiegelman BM. Molecular regulation of adipogenesis. Annu Rev Cell Dev Biol. 2001 ; 16 : 145-71. |
24 | Morrison RF, Farmer SR. Hormonal signaling and transcriptional control of adipocyte differentiation. J Nutr. 2000 ; 130 : 3116-21. DOI |
25 | Park YW. Clinical guidelines of treatment of obesity in adults. J Korean Med Assoc. 2003 ; 46 : 345-56. DOI |
26 | Kim KY. Song HJ. Hanyakpojehak. Seoul : Shinil Firm. 2002 : 547. |
27 | Kim DH, Han SB, Park JS, Han MJ. Fermentation of antler and its biological activity. Nat Prod Sci. 1994 ; 98 : 25-6. |
28 | Choi HJ, Kim EJ, Han MJ, Baek NI, Kim DH, Jung HG, Kim NJ. Hepatoprotective effect of fermented artemisia princeps pampanini by lactic acid bacteria. Nat Prod Sci. 1993 ; 38 : 245-53. |
29 | Kimura M, Chen F, Nakashima N, Kimura I, Asano A, Koya S. Antihyperglycemic effect of N-containing sugars derived from mulberry leaves in streptozotocin induced diabetic mice. J Traditional Med. 1995 ; 12 : 214-16. |
30 | Lee WC, Kim AJ, Kim SY. The study on the functional materials and effects of mulberry leaf. Food Sci Industry. 2003 ; 36 : 2-14. |
31 | Kim DG, Kim MB, Kim H, Park JH, Lim JP, Hong SH. Herb medicinal pharmacognosy. 3nd rev. ed. Seoul : Shinilbooks. 2005 : 77-9. |
32 | Kim DG, Kim MB, Kim H, Park JH, Lim JP, Hong SH. Herb medicinal pharmacognosy. 3nd rev. ed. Seoul : Shinilbooks. 2005 : 394-5. |
33 | Lim NY, Kwon GJ, Kim YS, Baik SK, Lim JR, Mun YJ, Woo WH. Inhibitory effect of methanolic extract from Adenophorae Radix on melanogenesis. Korean J Oriental Physiol Pathol. 2004 ; 18 : 747-53. 과학기술학회마을 |
34 | Compilation Committee of Korean Herbology. Korean herbology. Seoul : Younglimsa. 2010 : 206-7. |
35 | Lee JM, Seo BI, Park JH, Roh SS. Effects of water extracts from Phyllostachys Folium on hyperlipidemia and liver damage induced by alcohol. Kor J Herbology. 2011;26 : 31-6. 과학기술학회마을 |
36 | Kim DG, Kim MB, Kim H, Park JH, Lim JP, Hong SH. Herb medicinal pharmacognosy. 3nd rev. ed. Seoul : Shinilbooks. 2005 : 220-1. |
37 | Park SH, Yun SH, Kwon YM, Yeom SR, Kwon YD, Shin BC. Anti-inflammatory effect of Citrus Unshiu. J Rehabil Med Herb. 2005 ; 15 : 25-37. 과학기술학회마을 |
38 | Lee ES, Uhm KO, Lee YM, Han M, Lee M, Park JM, Suh PG, Park SH, Kim HS. CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells. Biochem Biophys Res Commun. 2007 ; 361 : 854-8. DOI ScienceOn |
39 | Devlin MJ, Yanovski SZ, Wilson GT, Obesity: what mental health professionals need to know. Am J Psychiatry. 2000 ; 157 : 854-66. DOI ScienceOn |
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