• Journal of Pharmaceutical Investigation
• /
• v.41 no.6
• /
• pp.363-369
• /
• 2011

In this study, we demonstrated the release behavior of carvedilol with the content of polyvinylpyrrolidone K-30 (PVP K-30) and the effect of citric acid and fumaric acid as acidifiers on the release behavior of drug. In addition, it tries to inquire into the release behavior difference of the carvedilol according to the manufacturing method. The release behavior of the tablets was compared with Dilatrand$^{(R)}$ in the simulated gastric fluid (pH1.2). Differential scanning calorimeter (DSC), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) were characterized for the physicochemical properties of the tablets. In case of mixing the carvedilol and PVP K-30, in case the ratio of the carvedilol and PVP K-30 was 1:5, the release behavior was the highest among. As well as the dissolution rate of tablets manufactured by lyophilization and rotary evaporator was higher than physical mixture. The dissolution rate of containing acidifiers was more improved. But, rather the excessive amount of the acidifier addition reduced the dissolution rate.

• Journal of Institute of Control, Robotics and Systems
• /
• v.22 no.10
• /
• pp.839-846
• /
• 2016

Bin picking is a task of picking a small object from a bin. For accurate bin picking, the 3D pose information, position, and orientation of a small object is required because the object is mixed with other objects of the same type in the bin. Using this 3D pose information, a robotic gripper can pick an object using exact distance and orientation measurements. In this paper, we propose a 3D vision technique for accurate measurement of 3D position and orientation of small objects, on which a paper label is stuck to the surface. We use a maximally stable extremal regions (MSERs) algorithm to detect the label areas in a left bin image acquired from a stereo camera. In each label area, image features are detected and their correlation with a right image is determined by a stereo vision technique. Then, the 3D position and orientation of the objects are measured accurately using a transformation from the camera coordinate system to the new label coordinate system. For stable measurement during a bin picking task, the pose information is filtered by averaging at fixed time intervals. Our experimental results indicate that the proposed technique yields pose accuracy between 0.4~0.5mm in positional measurements and $0.2-0.6^{\circ}$ in angle measurements.

• Journal of Preventive Medicine and Public Health
• /
• v.55 no.6
• /
• pp.578-585
• /
• 2022

Objectives: This study aimed to adapt the survey questionnaire designed by Moens et al. (2021) and determine the validity and reliability of the Arabic version of the survey in a sample of the Saudi population experiencing teleworking. Methods: The questionnaire includes 2 sections. The first consists of 13 items measuring the impact of extended telework during the coronavirus disease 2019 (COVID-19) crisis. The second section includes 6 items measuring the impact of the COVID-19 crisis on selfview of telework and digital meetings. The survey instrument was translated based on the guidelines for the cultural adaptation of self-administrated measures. Results: The reliability of the questionnaire responses was measured by Cronbach's alpha. The construct validity was checked through exploratory factor analysis followed by confirmatory factor analysis (CFA) to further assess the factor structure. CFA revealed that the model had excellent fit (root mean square error of approximation, 0.00; comparative fit index, 1.0; Tucker-Lewis index, 1; standardized root mean squared residual, 0.0). Conclusions: The Arabic version of the teleworking questionnaire had high reliability and good validity in assessing experiences and perceptions toward teleworking. While the validated survey examined perceptions and experiences during COVID-19, its use can be extended to capture experiences and perceptions during different crises.

• Journal of Biosystems Engineering
• /
• v.13 no.2
• /
• pp.28-37
• /
• 1988

This study was conducted to construct the soil bin system and associated microcomputer-based data acquisition system which is to be used for the effective evaluation of wheel performance. The soil bin system consists of four main parts; soil bin, carriage drive system, test carriage and soil processing carriage. The test carriage was constructed to measure the five performance parameters of testing wheels; pulling forte, motion resistance, sinkage and rotational speed of test wheel, and speed of test carriage. The test wheel is powered by a hydraulic system up to 8 ps. Soil processing carriage was designed to provide uniform test soil condition across the toil bin, and reproduction of soil conditions found satisfiable. The data acquisition system consists of APPLE II PLUS microcomputer, strain amplifier, I/O interface, A/D converter, digital counter and various transducers. It takes about 0.86 seconds to measure a set of performance parameters and store on the floppy disk simultaneously. Series of experiment showed that this system can be used effectively for evaluating the wheel performance associated with soil.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 1998.03a
• /
• pp.145-148
• /
• 1998

본 논문은 뉴스 비디오 데이터베이스를 구축하기 위한 장면 분할 기법 중 Color Histogram에서 각각의 RGB를 따로 계산하여 차이값을 세부화하는 장점과, x2 Histogram에서 차이값을 강조하는 장점을 이용하여 NTSC표준에 따른 가중치를 적용한 새로운 장면 분할 방법을 제안하였다. 제안 알고리즘의 성능 평가를 위한 실험 도메인은 국내 KBS, MBC, SBS 방송의 뉴스 비디오와 국외 CNN, NHK의 뉴스 비디오를 택하였다. 주어진 환경내에서 제안한 방법을 기존의 Color Histogram, x2 Histogram, 그리고 Bin to bin difference (B2B)과의 실험결과와 비교하여 효율적임을 보였으며, 임계치의 자동선택 가능성을 제시 하였다.

• Journal of the Korean Society of Manufacturing Technology Engineers
• /
• v.26 no.2
• /
• pp.223-229
• /
• 2017

Recently, robotic bin-picking tasks have drawn considerable attention, because flexibility is required in robotic assembly tasks. Generally, stereo camera systems have been used widely for robotic bin-picking, but these have two limitations: First, computational burden for solving correspondence problem on stereo images increases calculation time. Second, errors in image processing and camera calibration reduce accuracy. Moreover, the errors in robot kinematic parameters directly affect robot gripping. In this paper, we propose a method of correcting the bin-picking error by using trinocular vision system which consists of two stereo cameras andone hand-eye camera. First, the two stereo cameras, with wide viewing angle, measure object's pose roughly. Then, the 3rd hand-eye camera approaches the object, and corrects the previous measurement of the stereo camera system. Experimental results show usefulness of the proposed method.

• Polymer(Korea)
• /
• v.37 no.2
• /
• pp.127-134
• /
• 2013

The vascular endothelial cells are the inner layers of blood vessels. It regulates the function of blood vessels and proliferation of vascular smooth muscle cells. Poly(lactide-co-glycolic acid) (PLGA) is a biodegradable synthetic polymer with a well-controlled degradation rate and an acceptable mechanical strength. It can be easily fabricated into many shapes. Silk consists of 18 amino acids. It found important for attaching cells cultured in vitro, and maintaining cell functions. In this study, we fabricated silk/PLGA biomaterial hybrid films of 0, 10, 20, 40 and 80 wt% silk. We performed MTT, SEM, ELISA, and immunocytochemistry analyses. We confirmed the adhesion and the proliferation of HAECs on silk/PLGA according to the content of silk, and 40 wt% silk/PLGA hybrid films have superior adhesion and proliferation properties. These results demonstrate that silk/PLGA hybrid films provide suitable surfaces for HAECs, and there is the effect of silk on cell growth and proliferation.

• Polymer(Korea)
• /
• v.38 no.2
• /
• pp.164-170
• /
• 2014

This study was designed to find an appropriate biomaterial to proliferate Schwann cell (SC). Poly(lactic-co-glycolic acid) (PLGA) films mixed with demineralized bone particle (DBP), small intestine submucosa (SIS), and silk were fabricated by a solvent casting method. Analysis of MTT, SEM and RT-PCR were performed to confirm adhesion and proliferation of SC. Contact angle of films was assayed for hydrophilicity of films. We confirmed that PLGA/DBP 20% film showed higher hydrophilicity, promoted adhesion and proliferation of SC than other films. It was concluded that PLGA/DBP film can be applied for the scaffold biomaterials for the regeneration of central nerve system.

• Polymer(Korea)
• /
• v.31 no.6
• /
• pp.505-511
• /
• 2007

Poly(lactide-co-glycolide)(PLGA) and hyaluronic acid (HA) has been widely used as biocompatible scaffold materials to regenerate tissue. In this present study, we fabricated microporous PLGA and HA loaded PLGA scaffolds by a emusion freeze-drying method. In order to confirm that the release profile of cytokine or water-soluble drugs, we manufactured the granulocyte macrophage colony stimulating factor(GM-CSF) loaded PLGA and HA-PLGA scaffold. All scaffolds were characterized using scanning electron microscope(SEM), mercury porosimeter and wettability measurement. Cell proliferation and viability were assessed by a 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium-bromide (MTT) test. The porosity of HA-PLGA scaffold was greater than 95% with the total pore area of $261\;m^2/g$. The HA-FLGA scaffold exhibited well interconnected pores to allow greater cell adhesion and prolixferation. It was proven by higher cell viability in the HA-PLGA scaffold than PLGA alone. This may be due to the enhanced natural properties and higher water retention capacity of HA.

• Advances in concrete construction
• /
• v.13 no.2
• /
• pp.113-121
• /
• 2022

Polymers, particularly plastics, have been widely seen as an existential risk to the environment due to their contribution to pollution, carbon emissions and climate change. Many argue that it is possible to substantially ease the threat of plastics by engaging the public in reducing their use in day-to-day life and implementing efficient domestic waste management strategies. On the other hand, polymers and plastics in building and construction are considerably less problematic, if not attractive. In fact, the applications of polymers in construction have been continuously expanding. This is partly due to the developments made in this area being implemented within a sustainable development strategy. In this paper, the main applications of polymers in construction have been revisited and an overview of the research topics in each application has been briefly presented.