• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.6
• /
• pp.413-419
• /
• 2021

The purpose of this study was to investigate the ability to treat and prevent infection by multiple Gram-negative bacterial pathogens as a last choice option in the treatment of serious infections in clinical settings. The global spread of extended-spectrum 𝛽-lactamases (ESBLs) and/or carbapenemases in microorganisms are of enormous concern to health services because they are often associated with multi-drug resistance which significantly restricts the antibiotic treatment options. In this study, the antimicrobial resistance profiles of bacteria isolated from South Korean market-derived meat samples were determined by the disc diffusion method. PCR was used to detect the presence of antibiotic resistance genes and ESBL producing genes. In total, we tested 181 isolated colonies from 36 market-derived meat samples. Single PCR and DNA sequencing results revealed that genes blaVIM, blaBIC, blaKPC, and blaSIM were present in the bacteria isolated from retail meat. The bacteria in the meat were separately sequenced and based on alignment, four different bacteria were identified. These findings suggest that bacteria found in retail meats are a reservoir for the spreading of ESBL blaVIM, blaBIC, blaKPC, and blaSIM resistance genes and bacteria strains.

• Journal of Veterinary Science
• /
• v.25 no.2
• /
• pp.23.1-23.15
• /
• 2024

The widespread use of antimicrobials causes antibiotic resistance in bacteria. The use of butyric acid and its derivatives is an alternative tactic. This review summarizes the literature on the role of butyric acid in the body and provides further prospects for the clinical use of its derivatives and delivery methods to the animal body. Thus far, there is evidence confirming the vital role of butyric acid in the body and the effectiveness of its derivatives when used as animal medicines and growth stimulants. Butyric acid salts stimulate immunomodulatory activity by reducing microbial colonization of the intestine and suppressing inflammation. Extraintestinal effects occur against the background of hemoglobinopathy, hypercholesterolemia, insulin resistance, and cerebral ischemia. Butyric acid derivatives inhibit histone deacetylase. Aberrant histone deacetylase activity is associated with the development of certain types of cancer in humans. Feed additives containing butyric acid salts or tributyrin are used widely in animal husbandry. They improve the functional status of the intestine and accelerate animal growth and development. On the other hand, high concentrations of butyric acid stimulate the apoptosis of epithelial cells and disrupt the intestinal barrier function. This review highlights the biological activity and the mechanism of action of butyric acid, its salts, and esters, revealing their role in the treatment of various animal and human diseases. This paper also discussed the possibility of using butyric acid and its derivatives as surface modifiers of enterosorbents to obtain new drugs with bifunctional action.

• Journal of the Korea Society of Computer and Information
• /
• v.6 no.1
• /
• pp.7-13
• /
• 2001

As the density of VLSI increases, the conventional logic testing is not sufficient to completely detect the new faults generated in design and fabrication processing. Recently. IDDQ testing becomes very attractive since it can overcome the limitations of logic testing. This paper presents a new BIC for the internal current test in CMOS logic circuit. Our circuit is composed of Magnetoresistive current sensor, level shifter, comparator, reference voltage circuit and a circuit be IDDQ tested as a kind of self-testing fashion by using the proposed BIC.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
• /
• 2005.11a
• /
• pp.235-240
• /
• 2005

This paper presents a dual band circularly polarized microstrip patch antenna. The antenna consists of two corner truncated patches implemented in one plane and single feed point. The input signal is directly excited to the patch 2 and the patch 1 is fed from patch 2 by coupling between two patches. The antenna is operated at 900 MHz and 2.45 GHz bands and has the right hand circularly polarized radiation pattern at all. The measured gains of the antenna are 2.95 dBic at 900 MHz band and 4.6 dBic at 2.45 GHz band.

• Journal of the Korean Statistical Society
• /
• v.28 no.3
• /
• pp.371-387
• /
• 1999

For possibly nonstationary autoregressive moving average, modeling based on the original observations rather than the differenced observations is considered. Under this scheme, sample autocorrelation functions, parameter estimates, model diagnostic statistics, and prediction are all computed from the original data instead of the differenced data. The methods and results established under stationarity of data are shown to naturally extend to the nonstationarity of one autoregressive unit root. The sample ACF and PACF can be used for ARMA order determination. The BIC order is strongly consistent. The parameter estimates are asymptotically normal. The portmanteau statistic has chi-square distribution. The predictor is asymptotically equivalent to that based on the differenced data.

• The Korean Journal of Applied Statistics
• /
• v.22 no.4
• /
• pp.687-695
• /
• 2009

The Bayesian multiple change-point estimation has been applied to the daily means of ozone and PM10 data in Seoul for the period 1999. We focus on the detection of multiple change-points in the ozone and PM10 bivariate vectors by evaluating the posterior probabilities and Bayesian information criterion(BIC) using the stochastic approximation Monte Carlo(SAMC) algorithm. The result gives 5 change-points of mean vectors of ozone and PM10, which are related with the seasonal characteristics.

• Proceedings of the KIEE Conference
• /
• 2007.11c
• /
• pp.179-182
• /
• 2007

The Design and Optimization of a low-profile antenna for the Satellite Digital Audio Radio System(SDARS) using a Non-Dominated Sorting Genetic Algorithm(NSGA) is presented. a fairly omni-directional elevation gain pattern over 60 degrees < q <60 degrees are obtained. The average value of the LCP gain pattern is approximately 2 dBic. The heights of the antennas are less than 0.251. The cross polarized signal level is approximately 12 dBic less than the co-polarized signal level.

• Clinical and Experimental Pediatrics
• /
• v.59 no.sup1
• /
• pp.157-160
• /
• 2016

Coexistence of paroxysmal kinesigenic dyskinesia (PKD) with benign infantile convulsion (BIC) and centrotemporal spikes (CTS) is very rare. A 10-year-old girl presented with a 3-year history of frequent attacks of staggering while laughing and of suddenly collapsing while walking. Interictal electroencephalogram (EEG) revealed bilateral CTS, but no changes in EEG were observed during movement. The patient's medical history showed afebrile seizures 6 months after birth, while the family history showed that the patient's mother and relatives on the mother's side had similar dyskinesia. Genetic testing demonstrated that the patient had a heterozygous mutation, c.649_650insC, in the PRRT2 gene. To our knowledge, this constitutes only the second report of a patient with PKD, BIC, CTS, and a PRRT2 mutation.

• The Korean Journal of Applied Statistics
• /
• v.16 no.2
• /
• pp.365-376
• /
• 2003

In this paper we reviewed a variety of non-Gaussian time series models, and studied the model selection criteria such as AIC and BIC to select proper models. We also considered the likelihood ratio test and applied it to analysis of Polio data set.

• Journal of Environmental Health Sciences
• /
• v.35 no.3
• /
• pp.191-200
• /
• 2009

We investigated a trait of odor and the relationship between odor unit and odorous compounds using multiple regression analysis based on data compiled from Sihwa (SIC), Banwol (BIC), Banwol plating (BPIC) and Poseung industrial complex (PIC). These areas are odor control areas in Gyeonggi province. It was revealed that $NH_3$ and styrene concentrations in SIC and BPIC were relatively higher and $H_2S$ concentration especially in mc was more than five times higher than other areas. As a result of regression analysis using SAS, intensity of odor unit was highly related to concentrations of $H_2S$, TMA, styrene and n-valeraldehyde in SIC, $H_2S$, acetaldehyde, and butyraldehyde in BPIC and $NH_3$ in BIC.