• Journal of Microbiology and Biotechnology
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• v.32 no.2
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• pp.187-194
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• 2022

Two α-ʟ-arabinofuranosidases (BfdABF1 and BfdABF3) and a β-ᴅ-xylosidase (BfdXYL2) genes were cloned from Bifidobacterium dentium ATCC 27679, and functionally expressed in E. coli BL21(DE3). BfdABF1 showed the highest activity in 50 mM sodium acetate buffer at pH 5.0 and 25℃. This exo-enzyme could hydrolyze p-nitrophenyl arabinofuranoside, arabino-oligosaccharides (AOS), arabinoxylo-oligosaccharides (AXOS) such as 3²-α-ʟ-arabinofuranosyl-xylobiose (A³X), and 2³-α-ʟ-arabinofuranosyl-xylotriose (A²XX), whereas hardly hydrolyzed polymeric substrates such as debranched arabinan and arabinoxylans. BfdABF1 is a typical exo-ABF with the higher specific activity on the oligomeric substrates than the polymers. It prefers to α-(1,2)-ʟ-arabinofuranosidic linkages compared to α-(1,3)-linkages. Especially, BfdABF1 could slowly hydrolyze 2³,3³-di-α-ʟ-arabinofuranosyl-xylotriose (A²⁺³XX). Meanwhile, BfdABF3 showed the highest activity in sodium acetate at pH 6.0 and 50℃, and it has the exclusively high activities on AXOS such as A³X and A²XX. BfdABF3 mainly catalyzes the removal of ʟ-arabinose side chains from various AXOS. BfdXYL2 exhibited the highest activity in sodium citrate at pH 5.0 and 55℃, and it specifically hydrolyzed p-nitrophenyl xylopyranoside and xylo-oligosaccharides (XOS). Also, BfdXYL2 could slowly hydrolyze AOS and AXOS such as A³X. Based on the detailed hydrolytic modes of action of three exo-hydrolases (BfdABF1, BfdABF3, and BfdXYL2) from Bf. dentium, their probable roles in the hemiceullose-utilization system of Bf. dentium are proposed in the present study. These intracellular exo-hydrolases can synergistically produce ʟ-arabinose and ᴅ-xylose from various AOS, XOS, and AXOS.

• The korean journal of orthodontics
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• v.48 no.3
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• pp.172-181
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• 2018

Objective: This study was performed to investigate buccal facial depth (BFD) changes after extraction and nonextraction orthodontic treatments in post-adolescent and adult female patients, and to explore possible influencing factors. Methods: Twelve and nine female patients were enrolled in the extraction and nonextraction groups, respectively. Changes in BFD in the defined buccal region and six transverse and two coronal measuring planes were measured after registering pretreatment and posttreatment three-dimensional facial scans. Changes in posterior dentoalveolar arch widths were also measured. Treatment duration, changes in body mass index (BMI), and cephalometric variables were compared between the groups. Results: BFD in the buccal region decreased by approximately 1.45 mm in the extraction group, but no significant change was observed in the nonextraction group. In the extraction group, the decrease in BFD was identical between the two coronal measuring planes, whereas this differed among the six transverse measuring planes. Posterior dentoalveolar arch widths decreased in the extraction group, whereas these increased at the second premolar level in the nonextraction group. The treatment duration of the extraction group was twice that of the nonextraction group. No differences were found in BMI and Frankfort horizontal-mandibular plane angle changes between the groups. BFD changes in the buccal region moderately correlated with treatment duration and dental arch width change. Conclusions: BFD decreased in adult female patients undergoing extraction, and this may be influenced by the long treatment duration and constriction of dentoalveolar arch width. However, nonextraction treatment did not significantly alter BFD.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.3
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• pp.590-595
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• 2006

To investigate the anti-cancer effects of n-butanol fraction of DoJeokSeungKi-Tang extracts(nBFD) in U-937 cells. MTT assay was used to determine U-937 cells proliferation. Flow cytometry was used to detect apoptosis. Bcl-xl anti-apoptotic protein and caspase-3, p53 pro-apoptotic protein were examined by Western blot analysis. nBFD inhibited the proliferation of U-937 cells in a dose-dependent manner. The cells treated with nBFD showed a typical apoptotic process by increasing sub-Gl peak. nBFD reduced uptake of 3,3'dihexyloxacarbocyanine iodide(DiOC6) a fluorochrome which incorporates into cells dependent upon their mitochondrial transmembrane potential$({\triangle}{\psi}m)$. nBFD induced in U-937 cells apoptosis mainly via increasing sub-Gl peak, regulation of Bcl-xl, caspase-3 and p53 protein.

• Fire Science and Engineering
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• v.28 no.5
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• pp.44-51
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• 2014

In this study, the Mock-up office space experiments have been performed for the fire behavior analysis of the compartmented space used for the performance-based fire safety design of buildings. Mock-up test was conducted using the compartmented office space dimensions, which are 2.4 m wide, 3.6 m wide, and 2.4 m hight. Test was conducted with the combustible materials such as a desk, a chair, a computer ect. The fire load in the Mock-up office space was $18.74kg/m^2$. As a result, the temperature of the central compartment space to reach $600^{\circ}C$ were 394 to 408 s. The temperature of the corner near the entrance edge to reach $600^{\circ}C$ were 404 to 420 s. At this study, the temperature curve in the compartmented space has been predicted using the temperature data appling the BFD curve. The BFD curve factor based on the fire tests was determined by the maximum temperature of $900^{\circ}C$, 7 min to reach the maximum temperature, and the shape coefficient of 1.5. The initiating fire was rapidly increased to 9 min, and decreased.

• Bulletin of the Korean Mathematical Society
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• v.41 no.3
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• pp.473-482
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• 2004

Let D be an integral domain, I a proper ideal of D, and R =D[It, $t^{-1}$] a generalized Rees ring, where t is an indeterminate. For suitable conditions, we show that R satisfies the ACCP (resp., is a BFD, an FFD, a (pre-) Schreier domain, a G-GCD domain, a PVMD, a v-domain) if and only if D satisfies the ACCP (resp., is a BFD, an FFD, a (pre-) Schreier domain, a G-GCD domain, a PVMD, a v-domain).

• TTA Journal
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• s.99
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• pp.116-122
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• 2005

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.5
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• pp.61-72
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• 2019

The purpose of this study is to propose the clue of planning guideline for the elderly welfare center supporting the healthy life of the elderly through deriving the planning element of the elderly welfare center based on the Salutogenic Model(SM). The research method was proceeded with literature review. The meaning of Sense of Coherence(SOC) and Generalised Resistance Resources(GRR) which constitute Salutogenic Model is established. The correlation between SOC and GRR is analyzed. The conclusions of this study are as follows. First, EBD, BD, HD, UD, and BFD were studied as planning theories that could enhance the SOC of space. Second, based on the five planning theories, 43 planning elements needed for the elderly welfare center plan were derived. Third, as a result of classifying the plan elements based on the SOC, 'Manageability' is divided into 22 elements, 'Meaningfulness' is 11 and 'Comprehensibility' is 10 elements. Fourth, the details of the SOC items for each theory are as follows: BFD focuses on 'Manageability' with 'Manageability'(74%) and 'Comprehensibility'(26%), but 'Meaningfulness' does not exist. And UD regards 'Comprehensibility'(66%) as important, and 'Manageability' and 'Meaningfulness' as 17%. BD, on the other hand, has a high percentage of 'Meaningfulness'(70%), 'Comprehensibility'(21%) and 'Manageability'(9%). Next, the 'Manageability' of HD and EBD is 46%. And HD was 'Meaningfulness'(34%), 'Comprehensibility'(20%), and EBD was 'Meaningfulness'(30%) and 'Comprehensibility'(24%). The three items of SOC showed different distribution according to the spatial planning theory. As a result of the analysis, the spatial planning theory with the 'Comprehensibility' was related to Universal Design(UD), and the spatial planning theory with the 'Manageability' was related to Barrier-Free Design(BFD). In addition, the spatial planning theory of 'Meaningfulness' was related to Bio-philic Design(BD). Therefore, the plan of the elderly welfare center needs to approach the multidimensional design methodology to enhance the SOC(Sense of Coherence).

• Journal of computational fluids engineering
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• v.4 no.3
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• pp.28-34
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• 1999

The objective of this study is to present a numerical treatment of the pressure gradient when control volumes are sharing the interface between a homogeneous fluid and a porous medium. Two possible approaches, e.g. linear interpolation and extrapolation, are considered, and they are applied to the case of a steady and two-dimensional curved channel flow which is partially filled with a porous medium. It was found that the linear extrapolation produces a continuous velocity-field at the interface and thus is recommended. On the contrary, the linear interpolation entails a discontinuous velocity field at the interface, thereby warning its use in connection with the Brinkman-Forchheimer-extended Darcy flow model.

• Textile Coloration and Finishing
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• v.18 no.5 s.90
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• pp.72-79
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• 2006

There are many discrepancies between visually perceived color-difference and that which is quantified from an instrumental measurement when dark color samples are measured in the textile industry. The samples were prepared to represent these dark shades and the values of the instrumental results from conventional color-difference formulae(CIELAB, CMC, BFD II, CIE94, LCD99 and CIEDE2000). Those of visual assessment were compared. The experimental results show that the CIELAB formula gives the best performance over other formulae, and the CIEDE2000 formula for the color-difference according to chroma presents the worst performance. Therefore, we can say that the problems in color matching of dark shades are caused by imperfect formula, because the results obtained from a color-difference formulae are different and the CMC which is used as a standard color-difference formula in the textile industry is not correct. So, a revised color-difference formula is proposed in this study, to account for these problems.

• Journal of Veterinary Clinics
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• v.34 no.4
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• pp.310-312
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• 2017

A five-month-old African grey parrot was presented with alopecia, yellowish diarrhea, depression, and paralysis in the veterinary medical center, Chungbuk National University. The patient died 3 h later after hospitalization. For the accurate diagnosis, necropsy was performed and fungi were detected in the air sac. PCR was done for the viral detection which caused the alopecia, and for the species identification of fungi. Final diagnosis was a multi infection with avian circoviruses that caused psittacine beak and feather disease (PBFD), avian polyomavirus cause budgerigar fledgling disease (BFD), and Aspergillus fumigatus. This is the first report of a multi infection in South Korea.