• Title/Summary/Keyword: BCH

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An In Vitro and In Vivo Cholinesterase Inhibitory Activity of Pistacia khinjuk and Allium sativum Essential Oils

  • Ghajarbeygi, Peyman;Hajhoseini, Ashraf;Hosseini, Motahare-Sadat;Sharifan, Anoosheh
    • Journal of Pharmacopuncture
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    • v.22 no.4
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    • pp.231-238
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    • 2019
  • Objectives: Alzheimer's disease (AD), an overwhelming neurodegenerative disease, has deleterious effects on the brain that consequently causes memory loss and language impairment. This study was intended to investigate the neuroprotective activity of the two essential oils (EOs) from Iranian Pistacia khinjuk (PK) leaves and Allium sativum (AS) cloves against β-Amyloid 25-35 (Aβ25-35) induced elevation of cholinesterase enzymes in AD. Methods: The EOs of PK (PKEO) and AS (ASEO) were prepared and analyzed in terms of extraction yield, phenolic content, and cholinergic markers in vitro. Moreover, both were administered orally to adult male Wistar rats at concentrations of 1, 2, and 3%. The inhibitory potential of PKEO and ASEO was compared with Donepezil (0.75 mg/kg) against the high activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. Results: PKEO reached an inhibition rate of 83.6% and 81.4% against AChE and BChE, respectively. ASEO had lower anti-cholinesterase activity (65.4% and 31.5% for the inhibition AChE and BChE). PKEO was found to have more phenolic content than ASEO. A significantly positive correlation was observed between the total phenolics and anti-cholinesterase potential. In rats, both EOs decreased the enzyme activity in a concentration-dependent manner. As compared with Donepezil, the significant difference in the AChE and BChE inhibition occurred as rats were treated with PKEO 3% (p < 0.05). Conclusion: It could be concluded that PKEO and ASEO are potent inhibitors of AChE and BChE in rats that hold promise to be used for the treatment of AD.

The Arabidopsis beta-carotene hydroxylase gene promoter for a strong constitutive expression of transgene

  • Liang, Ying Shi;Bae, Hee-Jin;Kang, Sang-Ho;Lee, Theresa;Kim, Min Gab;Kim, Young-Mi;Ha, Sun-Hwa
    • Plant Biotechnology Reports
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    • v.3 no.4
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    • pp.325-331
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    • 2009
  • To efficiently express a gene of interest in transgenic plants, the choice of promoter is a crucial factor as it directly affects the expression of the transgene that will yield the desired phenotype. The Arabidopsis ${\beta}-carotene$ hydroxylase 1 gene (AtBch1) shows constitutive and ubiquitous expression and was thus selected as one of best candidates for constitutive promoter analysis by both in silico northern blotting and semi-quantitative RT-PCR analysis. To investigate AtBch1 promoter activity, the 1,981-bp 5'-upstream region of this gene was fused with ${\beta}-glucuronidase$ (GUS) and transformed into Arabidopsis. Through the molecular characterization of transgenic leaf tissues, the AtBch1 promoter generated strong activity that drives 1.8- and 2-fold higher GUS expression than the cauliflower mosaic virus 35S (35S) promoter at the transcriptional and translational levels, respectively. Furthermore, the GUS enzyme activity driven by the AtBch1 promoter was 2.8-fold higher than that produced by the 35S promoter. By histochemical GUS staining, the ubiquitous expression of the AtBch1 promoter was observed in all tissues of Arabidopsis. Semi-quantitative RT-PCR analysis with different tissues further showed that this promoter serves as a strong constitutive driver of transgene expression in dicot plants.

Algebraic-Coded Cryptosystem Using Primitive Binary BCH Codes (원시 이원 BCH 부호를 사용한 Algebraic-Coded Cryptosystem)

  • Jo Yong-Geon;Nam Gil-Hyeon
    • Journal of the military operations research society of Korea
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    • v.15 no.2
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    • pp.94-104
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    • 1989
  • The concept of Algebraic-Coded Cryptosystem has been proposed recently but its application has not been developed yet. The primary object of this paper is to implement the Private-Key Algebraic-Coded Cryptosystem by using the primitive binary BCH codes. In the analysis of the cryptosystein, we find out the fact that there may exist other key pairs $S_i\;and\;P_i$ satisfying $G^*=S_{i},G_{s},P_{i}$ where $SG_{s}P$ is the original cryptosystem made by use of the systematic code generation matrix $G_{s}$.

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Performance of M-ary Impulse Communications System over AWGN Channels (AWGN 채널에서 M진 임펄스 통신의 성능 분석)

  • 김동호;백승선;문용규;강희조
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.6 no.3
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    • pp.405-409
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    • 2002
  • Recently, the FCC commissioners approved limited uses of UWB, and have promised to review the standards to explore the potential of more flexible standards and to address the operation of additional types of UWB operations and technology. In this paper we study performances of UWB communication system according to M-ary schemes with BCH code. And under the AWGN channel, we analysis and compare error probability, the number of M-ary schemes to the two methods that pulse position modulation and pulse amplitude modulation.

Markov Model-Driven in Real-time Faulty Node Detection for Naval Distributed Control Networked Systems (마코브 연산 기반의 함정 분산 제어망을 위한 실시간 고장 노드 탐지 기법 연구)

  • Noh, Dong-Hee;Kim, Dong-Seong
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.11
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    • pp.1131-1135
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    • 2014
  • This paper proposes the enhanced faulty node detection scheme with hybrid algorithm using Markov-chain model on BCH (Bose-Chaudhuri-Hocquenghem) code in naval distributed control networked systems. The probabilistic model-driven approach, on Markov-chain model, in this paper uses the faulty weighting interval factors, which are based on the BCH code. In this scheme, the master node examines each slave-nodes continuously using three defined states : Good, Warning, Bad-state. These states change using the probabilistic calculation method. This method can improve the performance of detecting the faulty state node more efficiently. Simulation results show that the proposed method can improve the accuracy in faulty node detection scheme for real-time naval distributed control networked systems.

Cholinesterase Inhibitors Isolated from the Fruits Extract of Evodia officinalis (오수유의 Cholinesterase 저해활성 성분)

  • Lee, Ji-Young;Cha, Mi-Ran;Choi, Chun-Whan;Kim, Young-Sup;Lee, Bong-Ho;Ryu, Shi-Yong
    • Korean Journal of Pharmacognosy
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    • v.43 no.2
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    • pp.122-126
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    • 2012
  • The MeOH extract of Evodiae Fructus exhibited a significant inhibition on the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), in a dose dependent manner, respectively. The extensive bioactivity-guided fractionation process with the MeOH extract finally isolated four compounds, as rutaecarpine (1), evodiamine (2), limonin (3) and dehydroevodiamine (4). Among them, compound 2 exhibited specific inhibitory activity on BChE with the $IC_{50}$ values 1.7 ${\mu}g/ml$, whereas compound 4 showed the potent inhibition upon both AChE and BChE.

Block Turbo Codes applying low generating polynomials for High Code Rate (High Code Rate 달성을 위해 낮은 차수의 생성다항식을 적용한 Block Turbo Codes)

  • Kwon, Kyunghoon;Lee, Donghoon;Heo, Jun
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2011.11a
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    • pp.255-257
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    • 2011
  • 본 논문에서는 지상파 3D HDTV 방송 서비스를 제공하기 위하여 기존의 유럽형 HDTV 방송 서비스인 DVB-T2 전송 시스템의 채널 부호군 중 외부부호로 쓰이는 BCH 부호를 연판정 복호가 가능한 Block Turbo Code로 대체함으로써 생기는 성능 이득과 높은 부호율을 달성하기 위한 방법을 제안하였다. 기존의 DVB-T2 시스템에서 외부부호로 쓰이는 BCH 부호의 부호율의 경우 0.994정도의 높은 부호율을 가진다. 따라서 이에 준하는 높은 부호율을 가지면서 연판정 복호가 가능한 BTC 부호를 제안하고, 기존의 BTC 보다 더 높은 부호율을 가지는 BTC 부호를 설계한다. 모의 실험을 통하여 새롭게 제안된 BTC 에서도 반복복호의 이득이 생기는 것을 확인하고 기존 DVB-T2 시스템의 BCH 부호보다 성능이 우수함을 확인하였다.

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Butyrylcholineesterase(BChE) Inhibitors from a Brown Alga Sargassum sp.

  • Park, Soo-Hee;Ryu, Geon-Seek;Choi, Byoung-Wook;Lee, Bong-Ho
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.375.3-375.3
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    • 2002
  • In continuing search for BChE-inhibitory compounds from Korean marine algae. we found a highly potent inhibitory activity in the methanolic extract of Sargassum species. After partition of the MeOH extract between $CHCl_3$ and 30% MeOH. the former layer was subjected to a series of ODS flash chromatography. silica column chromatography. and preparative TLC to afford three compounds (1-3). Detailed structural elucidation of them is in progress. Compound 1 showed potent BChE-inhibitory activity with $IC_{50}$ values of 11 ng/mL. (omitted)

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Performance of Radio Communication DS/CDMA System with Diversity Technique and BCH Coding under Impulsive Noise and Nakagami Fading (임펄스 잡음과 나카가미 페이딩이 존재할 때 다이버시티 기법과 오류정정 부호를 이용한 무선통신 DS/CDMA 시스템의 오율 특성)

  • 김지웅;강희조;이권현
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.10 no.4
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    • pp.539-549
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    • 1999
  • In this paper, the bit error rare (BER) performance of DS/CDMA DQPSK communication system in the presence of multi access interference, impulsive noise and Nakagami fading is investigated. The DS/CDMA DQPSK communication system adopts Maximum Ratio Combining (MRC) diversity reception and error correcting BCH code technique to enhance system performance. Using the derived error probability equation, the error rate performance of DS/CDMA DQPSK communication system has been evaluated and shown in figures to discuss as a function of impulsive index(A), Gaussian noise to impulsive noise power ratio($\Gamma$'), multi access interference(Κ), Nakagami fading parameter(m), the number of diversity branch (L), the number of error correction symbol (t), PN code sequence length(N) and $E_b/N_0$. The error performance of DS/CDMA-MDPSK signals improve by adopting MRC diversity and BCH(15,7) coding technique in the environment of impulsive noise plus Nagakami fading. From the results, we known that proposed system is affected by multi access interference, impulsive noise and Nakagami fading in radio communication system environment. Also, BER performance of DS/CDMA DQPSK communication system cam be improved increasing either the power of desired signal or the value of Gaussian noise to impulsive noise power ratio. And BCH(15,7) code technique is more effective to restrain the affection of multi access, interference, impulsive noise and Nakagami fading in DS/CDMA DQPSK communication system than MRC diversity reception technique.

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THE ORPHAN STRUCTURE OF BCH(3, m) CODE

  • HWANG, GEUM-SUG
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.6 no.1
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    • pp.109-119
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    • 2002
  • If C is a code, an orphan is a coset without any parent. We investigate the structure of orphans of the code BCH(3, m). All weight 5 cosets and all weight 3 reduced cosets are orphans, and all weight 1,2 and 4 are not orphans. We conjecture that all weight 3 unreduced cosets are not orphans. We prove this conjecture for m = 4, 5.

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