• 제목/요약/키워드: BCC analysis

검색결과 219건 처리시간 0.034초

Exploratory Investigation of Genetic Associations with Basal Cell Carcinoma Risk: Genome-Wide Association Study in Jeju Island, Korea

  • Yun, Byung Min;Song, Jung-Kook;Lee, Ji-Young
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권17호
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    • pp.7443-7447
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    • 2014
  • Aim: Little is known about the genetic associations with Basal cell carcinoma (BCC) risk in non-Caucasian populations, in which BCC is rare, as in Korea. We here conducted a pilot genome-wide association study (GWAS) in 12 patients and 48 standard controls. Method: A total of 263,511 SNPs were analyzed with the Illumina HumanOmni1 Quad v1.0 DNA Analysis BeadChip for cases and Korean HapMap 570K for controls. Results: SNP-based analyses, based on the allele genetic model with adjustment for sex and age showed suggestive associations with BCC risk for 6 SNPs with a P-value (P < 0.0005). However, these associations were not statistically significant after Bonferroni correction: rs1040503, rs2216491, rs13407683, rs4751072, rs9891263, and rs1368474. In addition, results from gene-based analyses showed suggestive associations with BCC risk for 33 candidate genes with a P-value (P <0.0005). Consistent with previous GWAS and replication studies in Caucasian populations, PADI6, RHOU and SLC45A2 were identified as having null associations with BCC (P > 0.05), likely due to the smaller sample size. Conclusions: Although this was a small-scale negative study, to our knowledge, we have conducted the first GWAS for BCC risk in an Asian population. Further large studies in non-Caucasian populations are required to achieve statistical significance and confirm these findings.

매스미디어 운영에 따른 성과제고에 관한 연구 -국내 신문산업을 중심으로- (Improving Outcome of Mass Media)

  • 황종호
    • 한국콘텐츠학회논문지
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    • 제13권1호
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    • pp.366-375
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    • 2013
  • 최근 매스미디어 중 신문사의 경영은 인터넷뉴스, 방송 등의 확산으로 인해 신문사간의 경쟁뿐만 아니라 타 매체와의 경쟁도 심화되고 있는 현실이다. 따라서 본 연구에서는 자료포괄분석기법을 이용한 분석을 통해 국내 매스미디어인 신문발행업의 운영 효율성을 평가하여 운영성과 제고를 위한 벤치마킹 대상 신문사와 신문사가 개선해야할 투사값을 제시함으로써 효율적인 신문사 운영에 도움이 될 수 있는 근거를 제시하고자 한다. 분석을 위해 30개 신문발행사을 선정하였으며 평가항목으로는 CCR-O, BCC-O 효율성과 규모효율성(SE), 규모수익성(RTS)을 중심으로 평가하였으며 각각의 분석결과를 살펴보면 30개 신문발행사 중 CCR-O효율성이 1로 나타난 신문사가 10개, BCC-O효율성이 1로 나타난 신문사가 14개, 규모수익성분석을 위해 3가지 측면에서 분석 해 본 결과로는 규모의 보수증가가 1개 업체, 규모의 보수감소가 16업체, 규모의 보수불변이 13업체로 나타났다. 이와 같은 결과를 바탕으로 신문발행업체들이 효율적으로 프론티어에 도달하기 위한 투사값을 투입변수와 산출변수를 가지고 분석함으로써 신문발행업의 효율성에 영향을 주는 변수에 대한 정확한 이해와 기업경영 개선과 관련한 효율성 및 성과에 대해 분석하고자 한다.

블루베리 농가의 경영 효율성 및 생산성 분석 (Analysis on Productivity and Efficiency of Blueberry Farming)

  • 김원빈;엄지범
    • 한국유기농업학회지
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    • 제30권4호
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    • pp.499-516
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    • 2022
  • Blueberry producers' management is failing as a result of the price decline caused by an increase in blueberry imports and the accompanying deterioration in management. Consequently, an endeavor was undertaken to verify the measurement and impact from the standpoint of efficiency and productivity of blueberry management, and to offer an indication of management improvement through analysis. Using the Rural Development Administration's income survey data, the data for twenty-four blueberry farms was analyzed. First, the management effectiveness of blueberry cultivators was evaluated. Using the CCR model (0.7297) and the BCC model (08148), the efficiency of a farm was examined. When the efficiency is one, CCR is ten and BCC is fifteen, and in overall, it was found to be ineffective, the efficiency declined from 2018 to 2019, but climbed again in 2020, according to the annual analysis. The MPI index was then used to examine productivity. T2's MPI index was 1.3338, whereas T3's MPI index was 0.8896, demonstrating a considerable decline in TC. This indicates that technological progress is not being accomplished, necessitating the need for countermeasures. In order to improve the management efficiency of blueberry producers, it is necessary to reduce costs and improve receivable prices through producer organization, and to actively introduce new technologies.

지역에 따른 육상운송의 효율성과 생산성 분석 (The Changes of Technical Efficiency and Malmquist Productivity of Land Transportation by Region)

  • 박홍균
    • 한국항만경제학회지
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    • 제28권4호
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    • pp.59-77
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    • 2012
  • 육상운송은 서비스 제공자의 공급초과에 따른 구조적 문제와 비효율적인 요소들을 개선하기위하여 노력하고 있다. 따라서 육상화물운송시장은 경쟁력 강화를 위하여 지역별 물류구조를 지역의 산업특성에 따라 개선되어야 한다. 이를 위하여 본 연구는 지역별 육상운송의 운영 효율성과 생산성을 연구하였다. 사용한 자료는 각 시도별 육상운송물류의 5개년(2005-2009)간의 균형패널자료(balanced panel data)이용하였다. CCR과 BCC 분석에서 2005년-2008년 까지는 울산광역시가 가장 효율적이다. 2009년은 서울 특별시가 가장 효율적인 DMU이다. Window 분석결과는 광주광역시와 강원도가 0.062로 나타나 가장 안정적이다. Malmquist 생산성 분석 결과를 살펴보면, 충청남도와 충청북도의 경우 4기간 평균 생산성지수는 약 6.6%와 7.3% 증가하였다. 본 연구는 지역물류정책에서 육상운송의 구조개혁에 따른 효율화 방안을 제시하고 있다.

기저세포암종 탐지를 위한 피셔척도 필터링 기반 공초점 라만 스펙트럼 분류 (Confocal Raman Spectrum Classification Using Fisher Measure based Filtering for Basal Cell Carcinoma Detection)

  • 민소희;김진영;백성준;나승유;주재범
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2006년도 춘계학술대회 학술발표 논문집 제16권 제1호
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    • pp.203-207
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    • 2006
  • 본 논문에서는 공초점 라만 스펙트럼을 이용하여 기저세포암종(basal cell carcinoma, BCC)를 검출하는 문제에 대하여 다룬다. 특히, 라만 스펙트럼 측정시 발생하는 잡음 성분 및 변별력이 없는 성분을 제거하기 위한 방법으로 Fisher의 척도를 활용한 스펙트럼 필터링 방법을 제안한다. 특징벡터의 차원을 줄이기 위하여 주축분석방법을 사용하였고, 분류방법으로는 MAP(maximum a posteriori) 방법을 이용하였다. 실험결과 제안한 방법이 특징벡터의 차원을 줄일 수 있을 뿐만 아니라, 검출 결과도 향상됨을 확인하였다

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속도의존성 결정소성 모델 기반의 유한요소해석을 통한 BCC 금속의 변형 집합조직 예측 (Prediction of Deformation Texture in BCC Metals based on Rate-dependent Crystal Plasticity Finite Element Analysis)

  • 김동규;김재민;박원웅;임용택;이용신
    • 소성∙가공
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    • 제23권4호
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    • pp.231-237
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    • 2014
  • In the current study, a rate-dependent crystal plasticity finite element method (CPFEM) was used to simulate flow stress behavior and texture evolution of a body-centered cubic (BCC) crystalline material during plastic deformation at room temperature. To account for crystallographic slip and rotation, a rate-dependent crystal constitutive law with a hardening model was incorporated into an in-house finite element program, CAMPform3D. Microstructural heterogeneity and anisotropy were handled by assigning a crystallographic orientation to each integration point of the element and determining the stiffness matrix of the individual crystal. Uniaxial tensile tests of single crystals with different crystallographic orientations were simulated to determine the material parameters in the hardening model. The texture evolution during four different deformation modes - uniaxial tension, uniaxial compression, channel die compression, and simple shear deformation - was investigated based on the comparison with experimental data available in the literature.

신흥 기술의 단계적 벤치마킹을 위한 SOM, DEA와 AHP 방법의 순차 활용 (Sequential use of SOM, DEA and AHP method for the stepwise benchmarking of emerging technology)

  • Yu, Peng;Lee, Jang Hee
    • 지식경영연구
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    • 제13권5호
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    • pp.43-64
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    • 2012
  • Emerging technologies have significant implications in establishing competitive advantages and are characterized by continuous rapid development. Efficient benchmarking is more and more important in the development of emerging technologies. Similar input level and importance are two necessary criteria need to be considered for emerging technology's benchmarking. In this study, we proposed a sequential use of self-organizing map(SOM), data envelopment analysis(DEA) and analytical hierarchy process(AHP) method for the stepwise benchmarking of emerging technology. The proposed method uses two-level SOM to cluster the emerging technologies with similar required input levels together, then, in each cluster, uses DEA-BCC model to evaluate the efficiencies of the emerging technologies and do tier analysis to form tiers. On each tier, AHP rating method is used to calculate each emerging technology's importance priority. The optimal benchmarking path of each cluster is established by connecting the emerging technologies with the highest importance priority. In order to validate the proposed method, we apply it to a case of biotechnology. The result shows the proposed method can overcome difficulties in benchmarking, select suitable benchmarking targets and make the benchmarking process more efficient and reasonable.

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The thermal cycling stability of V-Ti based alloy

  • Park, Jeoung-Gun;Kim, Dong-Myung;Jang, Kuk-Jin;Han, Jai-Sung;Lee, Jai-Young
    • 한국수소및신에너지학회논문집
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    • 제9권3호
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    • pp.111-118
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    • 1998
  • The intrinsic degradation behavior of $(V_{0.53}Ti_{0.47})_{0.925}Fe_{0.075}$ alloy with BCC structure and the two plateau regions (the low and high plateau region) has been investigate during the temperature-induced hydrogen absorption-desorption cycling (thermal cycling). After 400 thermal cycles between room temperature and $600^{\circ}C$ under 10atm $H_2$, the total reversible hydrogen absorption capacity decreased by about 40%. From thermal desorption analysis it was found that the degradation behavior at each plateau region was different. In addition, XRD analysis showed that the crystal structure of the sample in de-hydrided state was changed from BCC to BCT after degradation, and that of the sample in hydrided state it was maintained as FCC although peaks were broadened after degradation. From the result of static isothermal hydrogenation treatment it were found that crystal structure change from BCC to BCT was caused by the thermal energy. TEM analysis showed that the peak broadening was due to the formation of an amorphous phase in FCC matrix.

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은행산업 진단방법론 개발 (Developing a Method for Diagnosing the Banking Industry)

  • 박경보;홍종의
    • 한국산학기술학회논문지
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    • 제16권1호
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    • pp.255-265
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    • 2015
  • 은행 산업의 글로벌화에 따라 은행의 내실이 중요해지고 있다. 내실을 위해 은행의 효율 생산성이 중요해짐에 따라 은행은 이를 향상시켜야 한다. 효율 생산성을 강화시키기 위해 은행의 현 상황을 분석할 방법론이 필요하나 부족한 상태다. 따라서 본 연구에서는 효율성 측정방법론인 DEA중 BCC모델과 생산성 측정방법론인 Malmquist모델을 기반으로 하여 은행의 효율 생산적 위치를 분석할 수 있는 진단방법론을 개발하였다. 모델의 타당성을 검사하기 위해 2007년부터 2012년까지의 은행 데이터를 기반으로 조사 분석을 실시하였다. 분석결과 본 연구의 BCC - Malmquist모델과 당시의 은행위치가 유사함을 분석할 수 있었다. 또한 2012년의 데이터에 나온 결과 값을 바탕으로 2013-2014년에 각 은행이 취한 효율 생산성 향상 방법이 흡사함을 분석 가능하였다. 따라서 본 분석방법론은 은행의 효율 생산적 위치를 파악하기 용이하며, 타 분야에 적용함으로써 경영전략적 시사점을 제공가능하다 사료된다.

컨테이너항만의 경쟁력 측정방법:AHP와 DEA접근 (A Measurement Way of Competition Power of Container Port: AHP and DEA Approach)

  • 박길영;오성동;박노경
    • 한국항만경제학회지
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    • 제21권1호
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    • pp.133-151
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    • 2005
  • The purpose of this paper is to investigate the international competition power between Korean ports and Chinese ports according to the port efficiency scores of DEA(Data Envelopment Analysis) by newly introducing the priority vector of AHP(Analytic Hierarchy Process) to the DEA method. Empirical analysis shows the followings: First, there was not big changes of DEA rankings when we use the input-oriented CCR and BCC models after introducing the AHP priority vectors to the input variables. Yantian Port's competition power was declined, but that of Busan Port was up in the BCC model. Second, there was some changes of DEA rankings when we use the output-oriented CCR and BCC models after introducing the AHP priority vectors to the output variables. Rankings of Dalian, Qingdao, Shanghai Ports were up. But Shekou, Yantian Ports showed the declined ranking position in the CCR model. In the BBC model, rankings of Shanghai and Busan Ports were up. But those of Shekou and Yantian Ports were declined. The main policy implication based on the findings of this study is that The Ministry of Maritime Affairs & Fisheries in Korea and China should introduce AHP and DEA approaches when they measure the international competition power by using the porrt efficiency scores of DEA.

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