• Title/Summary/Keyword: BCC analysis

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Exploratory Investigation of Genetic Associations with Basal Cell Carcinoma Risk: Genome-Wide Association Study in Jeju Island, Korea

  • Yun, Byung Min;Song, Jung-Kook;Lee, Ji-Young
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7443-7447
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    • 2014
  • Aim: Little is known about the genetic associations with Basal cell carcinoma (BCC) risk in non-Caucasian populations, in which BCC is rare, as in Korea. We here conducted a pilot genome-wide association study (GWAS) in 12 patients and 48 standard controls. Method: A total of 263,511 SNPs were analyzed with the Illumina HumanOmni1 Quad v1.0 DNA Analysis BeadChip for cases and Korean HapMap 570K for controls. Results: SNP-based analyses, based on the allele genetic model with adjustment for sex and age showed suggestive associations with BCC risk for 6 SNPs with a P-value (P < 0.0005). However, these associations were not statistically significant after Bonferroni correction: rs1040503, rs2216491, rs13407683, rs4751072, rs9891263, and rs1368474. In addition, results from gene-based analyses showed suggestive associations with BCC risk for 33 candidate genes with a P-value (P <0.0005). Consistent with previous GWAS and replication studies in Caucasian populations, PADI6, RHOU and SLC45A2 were identified as having null associations with BCC (P > 0.05), likely due to the smaller sample size. Conclusions: Although this was a small-scale negative study, to our knowledge, we have conducted the first GWAS for BCC risk in an Asian population. Further large studies in non-Caucasian populations are required to achieve statistical significance and confirm these findings.

Improving Outcome of Mass Media (매스미디어 운영에 따른 성과제고에 관한 연구 -국내 신문산업을 중심으로-)

  • Hwang, Jong-Ho
    • The Journal of the Korea Contents Association
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    • v.13 no.1
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    • pp.366-375
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    • 2013
  • Recently, management of Newspaper developmet of the internet news, broadcasting and free newspapers escalated competition between newspaper companies and other media companies as well as competition among newapaper companies. This paper analyzes the efficiency of Korean Newapaper using DEA model. We evaluate the CCR-O, BCC-O efficiency, SE and RTS of 30 Newspaper. We also suggest the Newpaper which can be benchmarked based on analyzed information. The result shows that ten Nespaper whose values of CCR-O efficiency are 1, and Fourteen Nespaper whose values of BCC efficiency are 1. RTS indicates IRS of 1 firms, DRS of 16 firms and CRS of 13 firms. To variables on the effectiveness of newspaper publishing companies for the understanding and performance analysis.

Analysis on Productivity and Efficiency of Blueberry Farming (블루베리 농가의 경영 효율성 및 생산성 분석)

  • Kim, Won-Bin;Um, Ji-Bum
    • Korean Journal of Organic Agriculture
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    • v.30 no.4
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    • pp.499-516
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    • 2022
  • Blueberry producers' management is failing as a result of the price decline caused by an increase in blueberry imports and the accompanying deterioration in management. Consequently, an endeavor was undertaken to verify the measurement and impact from the standpoint of efficiency and productivity of blueberry management, and to offer an indication of management improvement through analysis. Using the Rural Development Administration's income survey data, the data for twenty-four blueberry farms was analyzed. First, the management effectiveness of blueberry cultivators was evaluated. Using the CCR model (0.7297) and the BCC model (08148), the efficiency of a farm was examined. When the efficiency is one, CCR is ten and BCC is fifteen, and in overall, it was found to be ineffective, the efficiency declined from 2018 to 2019, but climbed again in 2020, according to the annual analysis. The MPI index was then used to examine productivity. T2's MPI index was 1.3338, whereas T3's MPI index was 0.8896, demonstrating a considerable decline in TC. This indicates that technological progress is not being accomplished, necessitating the need for countermeasures. In order to improve the management efficiency of blueberry producers, it is necessary to reduce costs and improve receivable prices through producer organization, and to actively introduce new technologies.

The Changes of Technical Efficiency and Malmquist Productivity of Land Transportation by Region (지역에 따른 육상운송의 효율성과 생산성 분석)

  • Park, Hong Gyun
    • Journal of Korea Port Economic Association
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    • v.28 no.4
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    • pp.59-77
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    • 2012
  • Inland transportation system has been improving inefficiencies and structural problems due to excess of supply. Therefore, inland transportation market needs to reform its regional logistics structure in order to increase its competitiveness. To improve the solution, the research studied efficiencies and productivity of inland transportation systems in regions. In order to obtain specific facts, each cities' five years of (2005-2009) balanced panel data on inland transportation system has been studied. According to CCR and BCC analysis, Ul-San has been evaluated as the most efficient DMU during 2005-2008. In addition, in 2009, Seoul was the most efficient DMU. Also, according to Window analysis, Gwan-Ju and Gwangwon-do scored 0.062. Therefore, they were estimated as stable DMUs. According to Malmquist productivity analysis, average productivity indexes of four terms of Chungcheongnam-do and Chungcheongbuk-do haves been increased to 6.6% and 7.3%. I hope this study contributes to the improvement of regional inland transportation system.

Confocal Raman Spectrum Classification Using Fisher Measure based Filtering for Basal Cell Carcinoma Detection (기저세포암종 탐지를 위한 피셔척도 필터링 기반 공초점 라만 스펙트럼 분류)

  • Min So-Hui;Kim Jin-Yeong;Baek Seong-Jun;Na Seung-Yu;Ju Jae-Beom
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2006.05a
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    • pp.203-207
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    • 2006
  • This paper deals with a problem of detecting BCC using confocal raman spectrum. Specially, we propose Fisher measure based filtering for rejection of frequency components being noisy or non-discriminative. we use PCA (principal component analysis) for reduction of feature space dimension. Also, we apply MAP detector for classification of BCC raman spectrum. The experimental results shows that our proposed method can reduce the feature dimension and also raise the detection ratio.

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Prediction of Deformation Texture in BCC Metals based on Rate-dependent Crystal Plasticity Finite Element Analysis (속도의존성 결정소성 모델 기반의 유한요소해석을 통한 BCC 금속의 변형 집합조직 예측)

  • Kim, D.K.;Kim, J.M.;Park, W.W.;Im, Y.T.;Lee, Y.S.
    • Transactions of Materials Processing
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    • v.23 no.4
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    • pp.231-237
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    • 2014
  • In the current study, a rate-dependent crystal plasticity finite element method (CPFEM) was used to simulate flow stress behavior and texture evolution of a body-centered cubic (BCC) crystalline material during plastic deformation at room temperature. To account for crystallographic slip and rotation, a rate-dependent crystal constitutive law with a hardening model was incorporated into an in-house finite element program, CAMPform3D. Microstructural heterogeneity and anisotropy were handled by assigning a crystallographic orientation to each integration point of the element and determining the stiffness matrix of the individual crystal. Uniaxial tensile tests of single crystals with different crystallographic orientations were simulated to determine the material parameters in the hardening model. The texture evolution during four different deformation modes - uniaxial tension, uniaxial compression, channel die compression, and simple shear deformation - was investigated based on the comparison with experimental data available in the literature.

Sequential use of SOM, DEA and AHP method for the stepwise benchmarking of emerging technology (신흥 기술의 단계적 벤치마킹을 위한 SOM, DEA와 AHP 방법의 순차 활용)

  • Yu, Peng;Lee, Jang Hee
    • Knowledge Management Research
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    • v.13 no.5
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    • pp.43-64
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    • 2012
  • Emerging technologies have significant implications in establishing competitive advantages and are characterized by continuous rapid development. Efficient benchmarking is more and more important in the development of emerging technologies. Similar input level and importance are two necessary criteria need to be considered for emerging technology's benchmarking. In this study, we proposed a sequential use of self-organizing map(SOM), data envelopment analysis(DEA) and analytical hierarchy process(AHP) method for the stepwise benchmarking of emerging technology. The proposed method uses two-level SOM to cluster the emerging technologies with similar required input levels together, then, in each cluster, uses DEA-BCC model to evaluate the efficiencies of the emerging technologies and do tier analysis to form tiers. On each tier, AHP rating method is used to calculate each emerging technology's importance priority. The optimal benchmarking path of each cluster is established by connecting the emerging technologies with the highest importance priority. In order to validate the proposed method, we apply it to a case of biotechnology. The result shows the proposed method can overcome difficulties in benchmarking, select suitable benchmarking targets and make the benchmarking process more efficient and reasonable.

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The thermal cycling stability of V-Ti based alloy

  • Park, Jeoung-Gun;Kim, Dong-Myung;Jang, Kuk-Jin;Han, Jai-Sung;Lee, Jai-Young
    • Transactions of the Korean hydrogen and new energy society
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    • v.9 no.3
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    • pp.111-118
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    • 1998
  • The intrinsic degradation behavior of $(V_{0.53}Ti_{0.47})_{0.925}Fe_{0.075}$ alloy with BCC structure and the two plateau regions (the low and high plateau region) has been investigate during the temperature-induced hydrogen absorption-desorption cycling (thermal cycling). After 400 thermal cycles between room temperature and $600^{\circ}C$ under 10atm $H_2$, the total reversible hydrogen absorption capacity decreased by about 40%. From thermal desorption analysis it was found that the degradation behavior at each plateau region was different. In addition, XRD analysis showed that the crystal structure of the sample in de-hydrided state was changed from BCC to BCT after degradation, and that of the sample in hydrided state it was maintained as FCC although peaks were broadened after degradation. From the result of static isothermal hydrogenation treatment it were found that crystal structure change from BCC to BCT was caused by the thermal energy. TEM analysis showed that the peak broadening was due to the formation of an amorphous phase in FCC matrix.

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Developing a Method for Diagnosing the Banking Industry (은행산업 진단방법론 개발)

  • Park, Kyung-Bo;Hong, Jong-Yi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.1
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    • pp.255-265
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    • 2015
  • The globalization of the banking industry has highlighted the importance of the internal stability of the banks. For internal stability, the efficiency and productivity of the bank becomes more important, and the bank must be improved. To improve the efficiency and productivity, a methodology for analyzing the current state of the bank's needs was made based on the BCC of DEA and the Malmquist productivity index. This model was developed as a diagnostic method that can analyze the efficiency and productivity of the bank. As a result of the analysis, the position of the bank and the position of the model studied were similar. The BCC-Malmquist model can be applied to the other areas and provide a management strategy.

A Measurement Way of Competition Power of Container Port: AHP and DEA Approach (컨테이너항만의 경쟁력 측정방법:AHP와 DEA접근)

  • 박길영;오성동;박노경
    • Journal of Korea Port Economic Association
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    • v.21 no.1
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    • pp.133-151
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    • 2005
  • The purpose of this paper is to investigate the international competition power between Korean ports and Chinese ports according to the port efficiency scores of DEA(Data Envelopment Analysis) by newly introducing the priority vector of AHP(Analytic Hierarchy Process) to the DEA method. Empirical analysis shows the followings: First, there was not big changes of DEA rankings when we use the input-oriented CCR and BCC models after introducing the AHP priority vectors to the input variables. Yantian Port's competition power was declined, but that of Busan Port was up in the BCC model. Second, there was some changes of DEA rankings when we use the output-oriented CCR and BCC models after introducing the AHP priority vectors to the output variables. Rankings of Dalian, Qingdao, Shanghai Ports were up. But Shekou, Yantian Ports showed the declined ranking position in the CCR model. In the BBC model, rankings of Shanghai and Busan Ports were up. But those of Shekou and Yantian Ports were declined. The main policy implication based on the findings of this study is that The Ministry of Maritime Affairs & Fisheries in Korea and China should introduce AHP and DEA approaches when they measure the international competition power by using the porrt efficiency scores of DEA.

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