• Title/Summary/Keyword: B72-3

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The Role of Radiation Therapy on Local Recurrence of Rectal Cancer (직장암에서 수술후 방사선치료의 역활)

  • Chung, Woong-Ki;Ahn, Sung-Ja;Nam, Taek-Keun;Nah, Byung-Sik;Kim, Young-Jin
    • Radiation Oncology Journal
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    • v.10 no.2
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    • pp.205-212
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    • 1992
  • Ninety five patients of rectal cancer treated with surgery with or without adjuvant radiation therapy since January 1982 to December 1990 at the Chonnam University Hospital were analysed retrospectively regarding local failure. Of these 95 patients 72 patients were treated with surgery alone and remaining 23 patients received postoperative radiation therapy to pelvis. There were 45 men and 50 women with 53 years of median age. Minimum follow-up period was 19 months and median was47 months (range, 19-125 months). Kaplan-Meier method was used to calculate actuarial risk of local recurrence and survival rate. Comparison between two groups was evaluated by Log rank test. Of total 95 patients twenty seven patients ($28.4\%$) developed local recurrence and 13 patients ($17.3\%$) developed local and distant metastasis concomitantly. Eighty nine percent (24/27) of patients developed local recurrence within 24 months. Pelvic organ adjacent to the primary tumor area was the most common site of initial local recurrence. Of 72 patients treated with surgery alone local recurrence developed in 24 patients. Of 17 patients with stage A and 81 (Gunderson-Sosin modification of Dukes' staging system) 6 patients experienced local recurrence ($31.2\%$). The local recurrence rate of B2 and B3 group was $29.9\%$ (7/33) and that of C2 and C3 was $54.7\%$ (11/19), respectively. There was statistically significant difference between two groups (p<0.05). Of 23 patients treated with definitive surgery and radiation therapy $10\%$ (1/10) recurred in B2 and B3 patients. This was slightly lower than C2 and C3 patients ($22.2\%$, 2/10) of similar policy, but revealed no statistically significant difference (p>0.05). In the patients of B2+3 local failure rate decreased when radiation therapy was added ($29.9\%$ vs $10\%$, p>0.05) and also similar results in C2+3 group ($34.7\%$ vs $22.2\%$, p<0.05). The local failure rate in relation to distance from the anal verge had no statistically significant difference.

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Study on the Chemical Change of Amino Acid and Vitamin of Rapeseed during Germination (발아에 의한 유채의 아미노산 및 비타민 함량의 조성변화)

  • 김인숙;한성희;한강완
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.6
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    • pp.1058-1062
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    • 1997
  • The objective of this was to investigate the technical feasibility of producing toxicant-free by germination. To this end, rapeseed(Brassica napus L.) was germinated at $25^{\circ}C$ for 120 hours, and the chemical compositions of amino acids and vitamins were determinated in every 24 hours during germination. The results obtained are summarized as follows: Before germination, rapeseed contained 5.4g/16g N of glutamic acid and high percentage of the other amino acids in order of Asp>Leu>His>Pro>Arg>Lys>Gly>Ser>Ala>Val. The amino acids were gradually decreased until 96 hours during germination had tendency to show a slight increase in 120 hours. Vitamin B$_1$, B$_2$and C contents in rapeseed before germination were found to be 0.11, 0.21 and 3.72mg% respectively, and the vitamin E was 423ug/g. The vitamin C greatly increased in 72 hours during germination, while the vitamin B group was drastically decreased in 72 hours. The results obtained by this method clearly demonstrate that germination process is very effective to the removal of toxicants in rapeseed.

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Design for Frequency Tripler Using Novel Bandpass Filter with Low Insertion Loss (낮은 삽입손실을 갖는 새로운 대역통과 필터를 이용한 주파수 3체배기 설계)

  • Min, Jun-Ki;Cho, Seung-Yong;Kim, Hyun-Jin;Kim, Yong-Hwan;Lee, Kyoung-Hak;Kim, Dae-Hee;Yun, Ho-Seok;Hong, Ui-Seok
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.10A
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    • pp.1031-1036
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    • 2006
  • This paper proposes a novel BPF structure with less insertion loss and small size instead of the existing coupled line BPF for the output of the tripler using APDP (Anti-Parallel Diode Pair). This proposed BPF consists of the interdigital capacitor and spiral open stub. The proposed BPF has the insertion loss of less than 0.7dB within the band $(16.41{\sim}19.23GHz)$. The conversion loss of the tripler is about $16.6{\sim}18.5dB$ $(flatness<{\pm}1dB)$ at $5.72{\sim}6.28GHz$ of fundamental frequency. Its fundamental frequency and the fifth harmonic suppression characteristic at 6GHz are -32.16dBc and -44.6dBc, respectively And its phase noise attenuation characteristic is about 9.5dB at 100kHz.

Cloning and Sequence Analysis of the trpB, trpA and 3' trpC(F) Gens of Vibrio metschnikovii Strain RH530 (Vibrio metschnikovii 균주 RH530의 trpB, trpA 그리고 3' trpC(F) 유전자의 클로닝 및 염기서열 결정)

  • Kwon, Yong-Tae;Kim, Jin-Oh;Yoo, Young-Dong;Rho, Hyune-Mo
    • Korean Journal of Microbiology
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    • v.32 no.2
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    • pp.120-125
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    • 1994
  • The genes, trpB, trpA and 3’ trpC(F) of Vibrio metschnikovii strain RH530 were cloned and sequenced. The trpB and trpA genes had open reading frames of 1,173 bp and 804 bp encoding 391 and 268 amino acids, respectively. The trpB and trpA genes had conventional ribosome-binding sequences and overlapped with each other by one nucleotide, suggesting that these two genes are translationally coupled. 115 nucleotide upstream the trpB start codon, tjere was an incomplete open reading frame of the 3’-end of the trpC(F). The amino acid sequences of trpB, trpA and trpC(F) of V. metschnikovii RH530 had identities of 64.2%, 82.4% and 73.7% respectively, for those of V. parahaemolyticus; 58.7%, 72.3% and 54.9%, respectively, for Salmonella typhimurium; and 42.6%. 54.1% and 12.5%, respectively, for brevibacterium lactofermentum. The genetic organization of these genes, especially in the noncoding region between trpC(F) and trpB, was distinct from that of Enterobacteriaceae.

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Changes in Chemical Components of Cheonggukjang Prepared with Germinated Soybeans during Fermentation (발아대두 청국장의 발효 중 화학성분의 변화)

  • Eom, Sang-Mi;Jung, Bo-Young;Oh, Hoon-Il
    • Journal of Applied Biological Chemistry
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    • v.52 no.3
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    • pp.133-141
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    • 2009
  • This study was carried out in order to investigate the changes in chemical components of four kinds of Cheonggukjang during fermentation. Three different kinds of Cheonggukjang were prepared with germinated soybeans using rice straw, Bacillus natto, Bacillus natto plus Aspergillus oryzae, and non-germinated soybeans using rice straw. The nitrogen contents increased significantly during fermentation in all kinds of Cheonggukjang. Especially germinated soybean Cheonggukjang prepared with A. oryzae plus B. natto showed approximately 1.3 to 3.0 fold higher values than the other Cheonggukjangs. Total free amino acid contents of all Cheonggukjangs increased with an increase in fermentation time until 60 h. Lysine content was highest in Cheonggukjang prepared with ungerminated soybean at 72 h of fermentation. Among free amino acids of germinated soybean Cheonggukjang prepared with rice straw, glutamic acid was highest (3.64 mg/g) after 72 h of fermentation. In Cheonggukjang prepared with mixed culture, glutamic acid content was 4.37 mg/g. Total carbohydrate contents of Cheonggukjang decreased rapidly with an increase in fermentation time except the ungerminated soybean Cheonggukjang, and the total carbohydrate contents varied from 9.81 to 14.04% after 72 h of fermentation. On the other hand, total carbohydrate contents of ungerminated soybean Cheonggukjang prepared with rice straw gradually decreased during fermentation. In conclusion, it is expected to increase the contents of functional constituents and to improve quality characteristics of Cheonggukjang when it is prepared with germinated soybeans using B. natto plus A. oryaze.

Performance of Laying Period of Two-way Crossbreed Parent Stock to Produce Laying-type Korean Native Commercial Chickens (산란 전용 토종 실용계 생산을 위한 2원교배 종계의 산란 능력 검정)

  • Kim, Chong-Dae;Choo, Hyo-Jun;Kang, Bo-Seok;Kim, Hak-Kyu;Heo, Kang-Nyeong;Lee, Myeong-Ji;Son, Bo-Ram;Suh, Ok-Suk;Choi, Hee-Cheol;Hong, Eui-Chul
    • Korean Journal of Poultry Science
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    • v.39 no.3
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    • pp.245-252
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    • 2012
  • This study was carried out to investigate the performance of laying period of two-crossbred of Korean native chickens for producing laying hens. A total of four hundred eighty female 2-crossbred chicks that restored strains and were aboriginal at National Institute of Animal Science. There were four crossbreds (4 replications/crossbred, 30 birds/replication) as A) C strain ${\times}$ Y strain, B) C strain ${\times}$ L strain, C) C strain ${\times}$ G strain, and D) C strain ${\times}$ W strain, respectively. There were no significant difference on age at first egg among crossbreds (P>0.05). Egg weight and body weight of B crossbred at first egg was higher than other crossbreds (P<0.05). Body weight of B crossbred was the highest 20 to 72 weeks (P<0.05), and C and D crossbreds were lower compared to A and B crossbreds (P<0.05). Average feed intake of B crossbred was the highest among crossbreds (P<0.05), and that of A crossbred was higher compared to C and D crossbreds (P<0.05). Weekly feed intake of four crossbreds decreased from 50 weeks. Weekly egg weight of B crossbred was the highest and that of D crossbred was the lowest among crossbreds (P<0.05). Feed conversion ratio of A and B crossbreds was lower than that of C and D crossbreds. Hen-house egg production of C crossbred was the highest among crossbreds until 26 weeks old (P<0.05), but there was no significant difference among crossbreds from at the age of 26 weeks (P>0.05). Hen-day egg production decreased after at the age of 38 weeks. Weekly egg production of A and B crossbreds was higher compared to C and D crossbreds at the age of 68~72 weeks (P<0.05). These results suggested the basic data on the record of laying period of 2-crossbreed Korean Native Chickens for producing laying hens.

Production of Vitamin $B_{12}$ by Using Protoplast Fusion between Bacillus natto and Bacillus megaterium (Bacillus natto 및 Bacillus megaterium의 원형질체 융합에 의한 Vitamin $B_{12}$의 생산)

  • Jin, Sung-Hyun;Park, Bub-Gyu;Roh, Myung-Hoon;Kim, Dong-Gyu;Ryu, Beung-Ho
    • Korean Journal of Food Science and Technology
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    • v.22 no.6
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    • pp.611-617
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    • 1990
  • This study was conducted to breed a high vitamin $B_{12}$ producer by the fusion of protoplasts between Bacillus natto and Bacillus megaterium. Auxotrophic mutants of Bacillus natto SH-34 ($thr^-try^-rif^r$) and Bacillus megaterium BK-13 ($arg^-ade^-lys^-str^r$) which showed high protease activity and production of vitamin $B_{12}$, respectively, were isolated for the fusion experiment. Protoplasts were induced by incubating the cells with lysis solution containing $500{\mu}/ml$ lysozyme, and the ratio of protoplast and regeneration formation were ranged from 99% and 67%, respectively. Fusion frequencies of fusants between Bacillus natto SH-34 and Bacillus megaterium BK-13 were appeared in the ranges of $1.0{\times}10^{-5}$ under the treatment of 30% PEG 6000 containing 3% PVP. The fusant, MNF-72 showed the highest product yield of $7.85{\mu}g/g-cell\;vitamin\;B_{12}$ in production medium. For the improvement of productivity, the immobilization of fusants with sodium alginate was carried out. In batch and continuous fermentation systems, the productivity were determined to be $0.58{\mu}g/ml.hr\;and\;0.80{\mu}g/ml.hr\;vitamin\;B_{12}$ under optimum condition, respectivity.

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Determination of Vitamin B6 Content using HPLC in Agricultural Products cultivated in Local Areas in Korea (HPLC를 이용한 지역 농산물의 비타민 B6 함량 분석)

  • Choi, So-Ra;Song, Eun-Ju;Song, Young-Eun;Choi, Min-Kyung;Han, Hyun-Ah;Lee, In-Sok;Shin, So-Hee;Lee, Ki-Kwon;Choi, Young-Min;Kim, Haeng-Ran
    • The Korean Journal of Food And Nutrition
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    • v.30 no.4
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    • pp.710-718
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    • 2017
  • Contents of water soluble vitamin $B_6$ in a total of 62 agricultural products cultivated in local areas in Korea were analyzed by high performance liquid chromatography with fluorescence detector (HPLC/FLD). To verify the method of vitamin $B_6$ analysis, a quality control chart was formulated with in-house control using a mixture of broccoli and shiitake mushrooms. Among cereals, high content of vitamin $B_6$ measured $234.3{\sim}260.3{\mu}g/100g$ in dried mung bean and soybean. Vitamin $B_6$ content of non-glutinous and glutinous black rice measured $105.0{\mu}g/100g$ and $129.7{\mu}g/100g$, respectively. In vegetables, high content of vitamin $B_6$ were measured in passion fruit ($104.3{\mu}g/100g$), gat ($55.7{\sim}84.3{\mu}g/100g$), gomchwi ($31.3{\sim}88.0{\mu}g/100g$) and garlic ($72.7{\sim}98.3{\mu}g/100g$). Among fruits, gold kiwi 'Zespri' and green kiwi 'Hayward' revealed high vitamin $B_6$ content of $116.3{\mu}g/100g$ and $78.7{\mu}g/100g$, respectively. In persimmons, daebongsi had high vitamin $B_6$ content ($36.0{\sim}72.7{\mu}g/100g$) than bansi and sweet persimmon. Vitamin $B_6$ content in dried jujube and persimmon increased more than $86.7{\mu}g/100g$ compared to fresh materials. Among specialty crops, green tea powder ($64.7{\sim}251.0{\mu}g/100g$) and sansuyu ($172.3{\mu}g/100g$) revealed high content. Of mushrooms, vitamin $B_6$ content of Sparassis crispa ($139.3{\mu}g/100g$) was the highest. Vitamin $B_6$ content information of agricultural products in local areas in Korea collected from this experiment will be used as valuable preliminary data for grasp national nutritional status.

Conservation of metal artifacts excavated from tumulus in Chodang-dong, Kangreung City (강릉시 초당동 고분 출토 금속유물 보존)

  • Yu, Jae-Eun
    • 보존과학연구
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    • s.21
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    • pp.77-99
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    • 2000
  • Tumuli located in Chodang-dong in Kangreung City are sitesexcavated by the Museum of Kangreung University in 1993.Ofthese sites, a gilt bronze crown and gilt bronze sword with ring pommel with a tri-leaf ornament were excavated from the B-16tumulus. Underneath the gilt bronze crown was the gilt bronzes word with ring pommel with tri-leaf ornament, and these artifacts were treated with Polyurethane foams on the spot followed by special measures for conservation. This manuscript describes measures for conservation andanalysis with regard to the gilt bronze crown, gilt bronze sword with ring pommel with tri-leaf ornament and gilt bronze beltornaments. Bronze on the gilt bronze crown was completely corroded, therefore it was consolidated together with soil in the back of the artifact with Paraloid B72 after cleaning. Polyurethanefoams bottom was finished by applying the mixture of Epoxy resinAW106 and HV935K with soil. On the sword with ring pommel, the wooden part of the hilt was coated with Paraloid B72 (in Xylene) and the blade was consolidated with Paraloid NAD-10 30% after desalting with Sodium sesquicarbonate method. The gilt bronzebelt ornaments were treated with 3% Benzotriazole, coated with Paraloid B72 and then joined by using Cyanlacrylate. Specimens for the gilt bronze crown and gilt bronze belt ornaments were produced and gilding layers were examined under a metallographic microscope. The gilt bronze crown and the gilt bronze belt ornament maintained relatively good gilding quality with uniform gilding layers. Analysis of wood for the sheath of the sword with ring pommel revealed it to be Juglans mandshurica. Further more, analysis of constituents for a blue colored grassbead from dissolution of Polyurethane foams found it to be from the $Na_2O$-CaO-$AI_2O_3$-$SiO_2$ family.

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