• Title/Summary/Keyword: B56

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Dual TORCs driven and B56 orchestrated signaling network guides eukaryotic cell migration

  • Kim, Lou W.
    • BMB Reports
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    • v.50 no.9
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    • pp.437-444
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    • 2017
  • Different types of eukaryotic cells may adopt seemingly distinct modes of directional cell migration. However, several core aspects are regarded common whether the movement is either ameoboidal or mesenchymal. The region of cells facing the attractive signal is often termed leading edge where lamellipodial structures dominates and the other end of the cell called rear end is often mediating cytoskeletal F-actin contraction involving Myosin-II. Dynamic remodeling of cell-to-matrix adhesion involving integrin is also evident in many types of migrating cells. All these three aspects of cell migration are significantly affected by signaling networks of TorC2, TorC1, and PP2A/B56. Here we review the current views of the mechanistic understanding of these regulatory signaling networks and how these networks affect eukaryotic cell migration.

PC-766B' and PC-766B, 16-Membered Maerolide Angiogenesis Inhibitors Produced by Nocardia sp. RK97-56

  • Ko, Hack-Ryong;Kakeya, Hideaki;Yoshida, Arika;Onose, Rie;Ueki, Masashi;Muroi, Makoto;Takatsuki, Akira;Matsuzaki, Hiroshi;Osada, Hiroyuki
    • Journal of Microbiology and Biotechnology
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    • v.12 no.5
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    • pp.829-833
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    • 2002
  • Angiogenesis is an essential event in a variety of physiological and pathological processes. Therefore, effective inhibition of this event is a promising strategy for treating angiogenesis-related diseases, including cancer. The current study investigated two unique bafilomycin-type macrolide inhibitors of angiogenesls, PC-766B' (1) and PC-766B (2). The strain RK97-56 which produced the inhibitors was identified as Nocardia sp. by chemotaxonomic analyses, and the purification of the inhibitors was guided by their anti-angiogenic activities. PC-766B' (1) and PC-766B (2) exhibited potent inhibitory activities towards endothelial cell migration stimulated by the vascular endothelial growth factor (VEGF).

Functions for RFID Middleware Development on Mobile Device Emulator (모바일 단말 에뮬레이터에서 RFID 미들웨어 구현을 위한 기능 연구)

  • Ye, Seoung-Bin;Han, Soon-Hee;Ceong, Hee-Taek
    • The Journal of the Korea institute of electronic communication sciences
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    • v.3 no.2
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    • pp.106-111
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    • 2008
  • At the ubiquitous computing, Mobile RFID, which the convergence RFID and mobile device, researches are core method and infra to service B2B, B2C, and B2B2C service domain. We propose the functions of middleware to develop the mobile RFID device. It consists of multi-code integrated recognition module, the reader control module, the module code interpretation, and Dispatcher module. These functions can recognize the tag of EPC/ISO and mCode type. We describe the zone file of local ODS and the implemented module to read the 13.56MHz tag.

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Design and Fabrication of SMD Type Backward Wave 3dB Coupler for PCS Basestation (PCS 기지국용 표면실장형 후진파 3dB 커플러의 설계 및 제작)

  • 박인식;김종규;신동호
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.35D no.6
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    • pp.1-7
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    • 1998
  • In this paper, SMD type backward wave 3dB coupler for PCS basestation application was designed, fabricated and measured. We designed that it could be replaced for commercial basestation system and it was 0.56 $\times$ 0.35 inches size. The test results show that coupler is well operated within frequency range of 1.75 ~ 1.98GHz, which is defined on PCS system. The coupler reveals insertion loss 0.295dB, isolation -30.31dB, amplitude balance 0.05dB, phase balance 0.02$^{\circ}$, input and output impedance matching -30.38dB, -39.72dB, respectively.

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13.56 MHz High Efficiency Class E Power Amplifier with Low Drain Voltage (낮은 드레인 전압을 가지는 13.56 MHz 고효율 Class E 전력증폭기)

  • Yi, Yearin;Jeong, Jinho
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.26 no.6
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    • pp.593-596
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    • 2015
  • In this paper, we design a high efficiency class E power amplifier operating at low drain bias voltage for wireless power transfers. A 13.56 MHz power amplifier is designed at drain bias voltage of 12.5 V using Si MOSFET with the breakdown voltage of 40 V. High quality-factor solenoidal inductor is designed and fabricated for use in output matching circuit to improve output power and efficiency. Input matching circuit simply consists of resistor and inductor to reduce the circuit area and improve the stability. The fabricated power amplifier shows the measured output power of 38.6 dBm with the gain of 16.6 dB and power added efficiency of 89.3 % at 13.56 MHz.

Notes on Korean Strobilomycetaceae (II) - On Boletellus - (한국산 귀신그물버섯과에 대한 고찰(II) - 밤그물버섯속 -)

  • An, Yong-Hwan
    • The Korean Journal of Mycology
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    • v.26 no.2 s.85
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    • pp.211-229
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    • 1998
  • To study the species diversity of the genus Boletellus in Korea, 56 specimens were collected from 1982 to 1996 at 20 locations including Odaesan. Collected specimens were observed and seven species among them were identified and described by observing macroscopic and microscopic characters, two of which were confirmed new to Korea: Boletellus chrysenteroides (Snell) Snell. Boletellus fallax Corner. Seven species were described here: Boletellus chrysenteroides (Snell) Snell, B. elatus Nagasawa, B. emodensis (Berk.) Singer, B. fallax Corner, B. obscurecoccineus $(V{\"{o}}hn)$ Singer, B. russellii (Frost) Gilbert, B. shichianus (Teng & Ling) Teng.

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Conformational Analysis of Cyclodextrins and Their Methylated Analogs (시클로 덱스티린과 그 메틸유도체의 구조분석)

  • Hee-Sook Choi
    • Journal of the Korean Chemical Society
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    • v.36 no.2
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    • pp.324-328
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    • 1992
  • The $^1H$ NMR chemical shifts and coupling constants for ${\alpha}$-, permethyl-${\alpha}$-, ${\beta}$-and permethyl-${\beta}$-cyclodextrins in neutral aqueous media were assigned based on the 470MHz spectra. In order to obtain accurate chemical shifts and coupling constants the experimental spectra were analyzed with the Raccoon spin simulation program. The rotamer distribution around the$C_{5-}C_6$ bond of the cyclodextrins evaluated from the coupling constants of $J_{56a}$ and $J_{56b}$. In our calculation of the ${\alpha}$-, and ${\beta}$-cycliodextrin showed that gg conformers were most favorable form and tg conformers were least favorable form. It is very interesting to note the changes in $J_{56a}$, $J_{56b}$ coupling constants of permethylated ${\alpha}$- and ${\beta}$-cyclodextrins from unmodified one. The gg conformers were more increased than unmodified one and instead of tg conformers gt conformers were least favorable one upon methylation.

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