• Title/Summary/Keyword: B16F1

검색결과 990건 처리시간 0.046초

담배 연기발생과 Tipping 재료와의 상관성 연구 (The Relationship Between Smoke-Yields and Tipping Materials of the Cigarette)

  • Kim, Young-Hoh;Lee, Young-Taek;Kim, Sung-Han;Kim, Chung-Ryul;Kim, Jong-Yeol;Shin, Chang-Ho;Lee, Keun-Hoi
    • 한국연초학회지
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    • 제20권1호
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    • pp.131-138
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    • 1998
  • In order to minimize the trial frequency in the new filter cigarette design, we studied the relationship between smoke yield and tipping materials of cigarette. A three levels full factorial design involving filament denier (X1,2.5-3.3d), Porosity of the acetate filter plug wrap (X2, 3,500-16,000CU) and porosity of the tip paper (X3, 400-1,200CU) was used. Three independent factors (Xl, X2, X3) were chosen for their effects on the various responses and the function was expressed in terms of a quadratic polynomial equation, Y : $\beta$o + $\beta$1Xl + $\beta$2X2 + $\beta$3X3 + $\beta$11Xl2 + $\beta$22X22+ $\beta$33X32 + $\beta$12X1X2 + $\beta$13XIX3 $\beta$23X2X3 which measures the linear, quadratic, and interaction effects. Twenty-nine trial numbers were obtained as a results of using a three levels full factorial design and it was analyzed by the multiple regression analysis with backward stepwise in STATISTICA/pc under restricted conditions. Tar yields of the cigarette was affected by porosity of tip paper (0.66), filament denier (0.47) and porosity of plug wrap (0.28) in the decreasing order, and linear effect of tip paper porosity (B3) and filament denier (91) were significant at a level of 0.01($\alpha$). The filament denier and tipping paper porosity interaction F ratio among three factors had a P-value of 0,000041, indicating higher interaction between these factors. Based on the analysis of variance, the model fitted for Tar (Y1) was significant at 5% confidence level and the coefficient of determination (0.96) was the proportion of variability in the data fitted for by the model.

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Effects of Phytase and Carbohydrases Supplementation to Diet with a Partial Replacement of Soybean Meal with Rapeseed Meal and Cottonseed Meal on Growth Performance and Nutrient Digestibility of Growing Pigs

  • Shim, Y.H.;Chae, B.J.;Lee, J.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권9호
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    • pp.1339-1347
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    • 2003
  • An experiment was conducted to investigate the effects of microbial phytase ($Natuphos^{(R)}$) supplementation in combination with carbohydrases (composed of enzymes targeted to soybean meal (SBM) dietary components such as $\alpha$-galactosides and galactomannans; $Endo-Power^{(R)}$) to corn-soybean meal based diet (CSD) and complex diet (CD) with a partial replacement of SBM with rape seed meal (RSM) and cotton seed meal (CSM) on growth performance and nutrient digestibility of growing pigs. A total of 168 growing pigs averaging $13.18{\pm}1.77kg$ of initial body weight was arranged as a $2{\times}2$ factorial design with main effects of diet types (corn-SBM based diet (CSD) and complex diets (CD; 5% of SBM was replaced with 2.5% of RSM and 2.5% of CSM in diet for phase I (0 to 3 weeks) and 6% of SBM was replaced with 3% of RSM and 3% of CSM in diet for phase II (4 to 7 weeks))) and enzyme supplementation (none and 0.1% of phytase (500 FTU/kg diet) and 0.1% of carbohydrases). The diet with enzyme application were formulated to have a 0.18% unit lower aP than diets without enzyme application. Each treatment had three replicates with 14 pigs per replicate. To determine supplementation effect of phytase and carbohydrases on ileal amino acid digestibility of SBM, RSM and CSM, a total of 18 T-cannulated pigs (initial body weight; $13.52{\pm}1.24kg$) were assigned to six dietary treatments in the present study. Dietary treatments in metabolic trial included 1) SBM diet, 2) SBM diet+with enzymes (phytase (500 FTU/kg) and carbohydrases at 0.1%, respectively), 3) CSM diet, 4) CSM diet+enzymes, 5) RSM diet and 6) RSM diet+enzymes. During whole experimental period (0 to 7 wks), there was no difference in growth performance between diets (CSD and CD). However, dietary phytase and carbohydrases supplementation significantly improved gain/feed ratio (G:F) of growing pigs. During the phase II (4-7 weeks), dietary phytase and carbohydrases supplementation significantly improved all fecal nutrient digestibilities (Dry matter (DM), gross energy (GE), crude protein (CP), crude fat (CF), calcium (Ca) and phosphorus (P)). Dietary phytase and carbohydrases supplementation improved significantly overall ileal amino acid digestibilities of SBM, RSM and CSM based diets (p<0.05). The simultaneous inclusion of phytase and carbohydrases in both of CSD and CD reduced feed cost per kg body weight gain (FCG). Also, results suggest that 2.5 to 3% of RSM and CSM, respectively, might be used as a protein source in growing pig diets without having an adverse effect on the growth performance and nutrient digestibility and simultaneous phytase and carbohydrases addition improves nutritional value of SBM, RSM and CSM by improving ileal amino acid digestibilities.

Virus의 경란전염이 차대의 잠작에 미치는 영향에 관한 연구 (Studies on the Generation-to-Generation Transmission of Cytoplasmic Polyhedrosis Virus and the Effect of Their Activation on the Induction in the Next Generation in the Silkworm, Bombyx mori L.)

  • 임종성;김근영
    • 한국잠사곤충학회지
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    • 제16권1호
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    • pp.85-92
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    • 1974
  • 1. 활성 virus T-CPV에 대한 유발현상은 잠103 및 잠104어느 것이나 male$\times$ female 및 male$\times$female 처리가 높았으며, 접중농도에 있어서 male$\times$female 및 male$\times$female 처리의 H-CPV단독 유발현상은 $10^{7}$ /m1이하에서 높은 경향이었다. 2. Formalin첨식에 의한 유발현상은 잠103 및 잠104 어느 것이나 male$\times$female 및 male$\times$female가 높은 경향이 있다. 3. 냉장처리에 의한 유발현상에서도 formalin첨식의 경우와 같은 경향이 있다. 물론, 병장처리에 의하여 중장형다각체병이 유발되는 것은 전대에 접종된 occult virus가 활성화한다는 것이라 생각할 수 있으나 그 유발되는 정도는 역시 occult virus와 관계되는 유전적, 생리적 및 환경적 여러가지 요인들을 생각할 수 있다. 따라서 실제적인 저온에 의한 유발관계에서 사육환경을 지배하는 사육의 온습도, 생리적요인을 지배하는 엽질 등을 감안해야 할 것이다. 본 시험결과에서 보면 occult virus가 차대에 경란전달되어 사육중 유발요인에 따라서 활성화하는 것은 분명하다. 그러나 지금까지 occult virus를 찾아낼 수 있는 방법은 전자현미경 및 혈청학적인 기술에 의존해도 불가능하다. 따라서 잠종을 생산하는 과정에서 occult virus의 유무를 확인할 수 있는 방법은 active virus가 검출되는 나방(모아)을 대상으로 하는 경우로 제한하여 시험을 해야 할 것이다. 여기서 또한 밝혀져야 하는 것은 occult virus 경란전달과 sublethal infection에 의한 경란전달의 차이점인 것이다. 그리고 현재 우리가 보유하고 있는 품종별로 occult virus의 잠재된 상태를 유발요인별로 검토하므로서 저항성 품종육성에도 좋은 자료가 될 것으로 생각한다.

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한우의 체중 성장곡선 모수 추정을 위한 체중 측정 자료의 최적 범위에 관한 연구 (Study on the Optimum Range of Weight-Age Data for Estimation of Growth Curve Parameters of Hanwoo)

  • 조용민;윤호백;박병호;안병석;전병순;박영일
    • Journal of Animal Science and Technology
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    • 제44권2호
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    • pp.165-170
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    • 2002
  • 본 연구는 한우의 성장형태 분석을 위한 성장곡선 모수 추정시 이용하는 체중 측정자료의 최적 월령을 결정하기 위해 실시하였다. 분석에 이용한 자료는 농협 한우개량부에서 사육된 한우 수소 1,133두의 일령별 체중자료를 이용하였으며, 비선형 회귀모형인 Gompertz 모형으로 성장곡선을 추정하였다. 24개월까지 측정한 자료에 대해 14개월부터 2개월 단위로 최종 자료입력 시기를 분할한 6개의 측정종료 월령별 체중자료에 대해 추정한 성장곡선 모수 가운데 성숙체중(A)은 22개월령과 24개월령의 추정치 평균간 차이에 유의성이 없었으며, 성숙률(k) 추정치는 18-24개월령의 추정치 평균간 차이가 유의성이 없는 것으로 나타났다.(p$<$0.05). 측정종료 월령별 성숙체중(A) 추정치간의 상관 계수는 22개월령과 24개월령간에 0.93으로 가장 높게 나타났으며, 성숙률(k) 추정치간의 상관계수는 18-24개월령간에 0.91-0.99로 높게 나타났다(p$<$0.05). 성숙체중과 성숙률 추정치간의 상관은 12개월령의 경우 0.84로 높게 추정되었으나, 22개월령과 24개월령의 경우 0.12 및 0.10으로 추정되어 체중자료의 최종입력 시기가 연장됨에 따라 추정 모수간의 상관이 낮아지는 것으로 나타났다. 따라서 한우의 체중 성장 형태를 분석하기 위한 성장곡선 추정을 위한 자료의 최종 입력시기의 최적 월령은 22개월령 이상으로 사료된다.

Rifampicin단독내성 폐결핵 (Mono-Rifampicin-Resistant Pulmonary Tuberculosis)

  • 심태선;이기만;임채만;이상도;고윤석;김우성;김동순;김원동
    • Tuberculosis and Respiratory Diseases
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    • 제46권5호
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    • pp.618-627
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    • 1999
  • 연구배경 : Rifampicin (RFP)은 결핵단기요법의 근간이 되는 중요한 약제이다. RFP내성 결핵균은 대부분 isoniazid (INH)에도 내성이며, 따라서 RFP내성은 다제약제내성의 지표이다. 그러나 최근 서구에서는 드문 것으로 알려진 RFP단독내성결핵이, 특히 HIV감염과 연관되어 많은 빈도로 보고되었다. 따라서 서구와는 다른 환경을 가진 국내에서 RFP단독내성결핵의 빈도, 가능한 원인들, 및 임상상을 알아보고자 하였다. 대상 및 방법 : 1990년 1월부터 1997년 8월까지 서울중앙병원에서 대한결핵협회에 의뢰하여 결핵균 감수성검사 결과가 확인된 699명(921검체)중 INH감수성, RFP내성결과를 보인 총 18명(31검체)을 대상으로 의무기록을 검토하였다. 과거결핵의 병력, 약제복용력, 동반된 전신질환 유무, HIV검사 여부, 위장질환 여부, 감수성 결과의 변화 양상, 그리고 RFP단독내성 확인후 약제의 변경등 임상 경과를 고찰하였다. 또한 보관된 6 균주는 염기서열결정법으로 rpoB유전자의 돌연변이 양상을 확인하였다. 결 과 : 18명의 평균나이는 $43{\pm}14$세였고 남녀비는 12 : 6이었다. 18명중 16명(89%)에서 과거 결핵을 앓은 병력이 있었고, 이 중 약제복용력이 확인된 12명중 11명은 불규칙하게 약제를 복용하였다. 특기할 만한 위장질환을 진단받은 병력은 없었으며, RFP을 단독으로 복용한 병력도 없었다. 기저질환으로 당뇨병이 4예에서 있었다. HIV검사가 시행된 2명 모두 음성이었다. 11명에서 감수성검사가 2회 이상 반복 시행되었는데, 6명에서는 RFP단독내성을 유지하였고 5명에서는 다제내성으로 바뀌었다. 8명(44%)은 완치되었으며, 6명(33%)은 치료실패하였고 3명(17%)은 추적검사에서 소실되었으며, 1명은 아직 치료중이다. rpoB 유전자 염기서열결정법을 시행한 6균주중 5예에서 rpoB유전자 돌연변이가 발견되었으나 새로운 형태의 돌연변이는 없었다. 결 론 : HIV감염율이 서구에 비하여 낮은 국내에서 RFP단독내성 폐결핵의 임상상은 다제내성결핵과 유사하였다. 그러나 일부 RFP단독내성결핵은 RFP을 포함한 1차약제만으로도 완치가 가능하였고, 이는 RFP 단독내성이 다제내성결핵과는 다른 부류일 가능성도 시사하였다.

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참당귀 세미 추출물의 미백 및 항산화 효과 (Whitening and Antioxidant Effects of Extracts from Angelica gigas Nakai Thin Root)

  • 이상훈;박정용;서경혜;최장남;이윤정;문윤호;허목;박우태;허윤찬;장재기;구성철
    • 한국자원식물학회지
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    • 제34권1호
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    • pp.37-43
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    • 2021
  • 본 연구는 참당귀 가공 시에 버려지는 부산물인 세미를 기능성 화장품 원료로 활용가능성이 있는지 평가하기 위해 수행하였다. MTS assay 수행결과 70% 주정을 이용한 뿌리 부위별 추출물의 경우 처리농도 25 ~ 200 ㎍/mL까지 세포독성이 없었다. 추출물 200 ㎍/mL를 처리하였을 때의 melanin 생성 억제효과는 추출 부위별로 12% ~ 19%로 나타났으며, 세미와 약재의 melanin 생성 억제효과가 비슷하게 나타났다. 그리고 DPPH radical 소거능이 50%에 달하는 IC50 값은 세미 677.9 ± 30.5 ㎍/mL, 약재 728.0 ± 42.4 ㎍/mL로 나타났고, ABTS radical 소거능이 50%에 달하는 IC50 값은 세미 114.9 ± 0.1 ㎍/mL, 약재 173.6 ± 1.3 ㎍/mL으로 나타나 세미가 약재보다 항산화활성이 높게 나타났다. 따라서 본 실험결과를 고려해 봤을 때, 부산물인 세미는 기능성 화장품 원료로 이용 가능성이 높은 것으로 생각된다.

잦은 감기나 만성 비염을 동반한 마른 체형 소아에 대한 보폐성장증보탕 (補肺成長增補湯)의 체중개선 효과 - 의무기록 분석 - (The Weight Gain Effects of the Bofesungjangjeungbo-tang (Bǔfèichéngzhǎngzēngbǔ-tang) on Under-weight Korean Preschool Children with Frequent Common Cold or Chronic Rhinitis - Analysis of Medical Records -)

  • 김기준;이준석;윤지현;류봉하;백희영
    • 대한한방소아과학회지
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    • 제26권4호
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    • pp.44-50
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    • 2012
  • Objectives: We investigated weight gain effects of the Bofesungjangjeungbo-tang ($B\check{u}f\grave{e}ich\acute{e}ngzh\check{a}ngz\bar{e}ngb\check{u}$-tang) on thin Korean preschool children with frequent common cold or chronic rhinitis Methods Bofesungjangjeungbo-tang was empirically composed of 14 herbs for treating indigestion, and common cold or chronic rhinitis. We analyzed 60 preschool children who have visited Kim Kijoon Oriental Clinic BOM from Jan. 1, 2006 to Aug. 31, 2011 with three criteria: 1) 2~5yrs of age and BMI<50th percentile 2) children those who had taken the Bofesungjangjeungbo-tang for 1~3 month (s), 3) Availability of records on before/after treatment within 3 months. Weight gain of the children after treatment was evaluated by the changes of BMI percentile compared to pre-treatment. Results Bofesungjangjeungbo-tang significantly improved BMI percentile in all groups (1 month: $21.33{\pm}10.04$ vs $26.43{\pm}13.16$, p<0.001; 2 months: $21.90{\pm}10.28$ vs $29.03{\pm}15.06$, p<0.001; 3 months: $19.06{\pm}10.04$ vs $35.71{\pm}17.40$, p=0.001). Gender, age and pre-treatment BMI had no significant effects on the effectiveness of Bofesungjangjeungbo-tang. Conclusions: Bofesungjangjeungbo-tang positively affected weight gain in 2~5yrs Korean preschool children with BMI below 50 percentile within 1~3 month (s) of treatment. However, additional studies on functional dyspepsia or the change of energy intake are needed to understand the factors related to weight gains.

오배자 BuOH층에서 분리한 1,2,3,4,6-penta-O-galloyl-$\beta$-D-glucose의 세포간교통 회복 및 혁관형성 억제작용에 대한 효과 (Effect of 1,2,3,4,6-penta-O-galloyl-$\beta$-D-glucose isolated from Galla Rhois on gap junctional intercellular communication and antiangiogenic activity)

  • 허정은;이효정;송규용;차배천;김한성;유동열;유시용;김성훈
    • 동의생리병리학회지
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    • 제16권3호
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    • pp.452-457
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    • 2002
  • Galla Rhois is a gallnut of Rhus javanica Linne used for treatment of diarrhea, hemorrhage, cough, leukorrhea and toxic tumor etc in oriental medicine. For the evaluation of antitumor effect of Galla Rhois, activity based fractionation was done. We isolated an effective compound and identified 1,2,3,4,6-penta-O-galloyl-β-D-glucose(PGG) by photometric analysis such as NMR and MASS. Then, we studied the angiogenic activity of PGG. It showed a cytotoxicity against SK-OV-3, SK-OV-3, HT1080 with IC/sub 50/ of 50 ug/ml approximately. It also effectively inhibited proliferation of HUVEC cells treated by bFGF to 30% of control at 20 ug/ml and cell migration to 80% at 10 ug in a dose dependent fashion. Tube formation of HUVEC cells on matrigel was effectively suppressed from 2.5 ug/ml of concentration by PGG. Moreover, it effectively recovered the dysfunction of gap junctional intercellular communication in WB-F344 rat liver epithelial cells caused by hydrogen peroxide at 4 ug/ml suggesting it potently can inhibit tumor promotion. Taken together, it indicates 1,2,3,4,6-penta-O-galloyl- β -D-glucose has antiangiogenic activity.

벼 중만생 복합내병 직파적응성 "동진2호" (A New Medium-late Maturity Rice Cultivar, "Dongjin2" with Direct Seeding Adaptability and Multiple Disease Resistances)

  • 김보경;고종철;백만기;남정권;하기용;김기영;이재길;고재권;백소현;김정곤
    • 한국육종학회지
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    • 제40권3호
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    • pp.295-298
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    • 2008
  • "동진 2호" 품종은 작물과학원 호남농업연구소에서 2005년도에 육성한 중만생 복합내병성 직파적응성 품종으로 주요특성과 수량성을 요약하면 다음과 같다. 1. 출수기는 담수직파와 건답직파에서 8월 16일, 8월 21일로 주안벼보다 3~5일 늦으며, 호남평야지 및 영남평야지 보통기 보비 이앙재배에서는 평균 출수기가 8월 13일로 남평벼보다 3일정도 빠른 중만생종이다. 2. 간장은 70 cm로 남평벼 보다 8 cm 작고 이앙재배에서 주당수수는 남평벼와 같고 수당립수는 많다. 등숙비율은 다소 떨어지고 현미천립중은 24.2 g으로 중립종에 속한다. 3. 도열병에는 중강, 흰잎마름병 및 줄무늬잎마름병에는 강하나 기타 바이러스병이나 멸구 및 매미충류에는 약한 반응을 보였다. 4. 수발아 및 냉수처리 임실율은 남평벼와 비슷하거나 같았으며 냉수시 출수는 3일 지연되었다. 5. 쌀수량은 담수직파에서 571 kg/10a으로 주안벼보다 12%, 건답직파에서 539 kg/10a 으로 7% 증수되었으며 평야지 이앙재배에서는 574 kg/10a으로 6% 증수하였다. 6. 쌀은 심복백이 거의 없으며 투명도는 남평벼 수준으로 맑고 투명하다. 단백질 함량은 남평벼 보다 낮고 제현율과 도정율은 높았다. 7. 동진2호는 충남 이남 평야지(충남, 전남북, 경남북) 이앙재배 및 담수직파재배에 알맞은 품종이다.

장티브스에 관한 임상적 관찰 (Clinical review of Typhoid Fever Patients)

  • 최정신
    • 대한간호학회지
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    • 제6권1호
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    • pp.60-71
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    • 1976
  • The author reviewed the medical records of 96 typhoid fever patients who were diagnosed, admitted, and treated at Sea grave Memorial Hospital from January 1 , 1973 through August 31, 1975. Diagnosis was determined by clinical observation, aerology and bacteriology, eighty patients were treated medically, the remaining 16 patients required surgical intervention. The following results were obtained: 1) The age distribution of the patients revealed that 33.3% wert between 10 and 19 years old 21.9% were between 20 and 29, and 19.8% were between 30 and 39. The majority of patients were from these more active age groups. Male to female sex ratio was 1.3 : 1 2) Seasonal distribution was observed. Most illness occurred in the summer and autumn month 5. 3) 84. 3%of the patients came from farm families. 4) Duration between onset and admission averaged 16.0 days. The group without compilations was admitted after an average of 15. 1 days; The group with complications was ad-matted after an average of 19.4 days. 5) Methods of treatment before admission were as follows: 10.4% at medical clinics, 61, 5% at pharmacies (antibiotics 47.9%, other. drugs 13.5%), 7.3% by herb medications, 20.8% had no treatment. 6) Main clinical symptoms were as follows: fever 93.8%, headache 47.9%, abdominal pain 47.9%, chills 38.5%, cough 36.5%, general weakness 26.0%, nausea e vomiting 24.0% and generalized pain 21.9%. 7) Temperature of patients on admission: 22.9% were 39f or more, 67.6% were between 37℃ and 38℃, and 9.4% were 37℃ or less. 8) Occurrence of intensional bleeding after onset of disease averaged 9.3 days; perforation occurred at an average of 19. 1 days. 9) Interval between onset of major complication and surgical intervention averaged 2.8 days. 10) Among the 68 patients who underwent the bacteriological test the positive rate was 44.1% (30). The positive ,ales to, each separate culture method were as follows: 20.4% in the blood culture, 40.4% in the stool culture and 6.7% in the urine culture. Among these bacteriological positive patients 15 patients had a negative results or less than 160 titer of vidal reaction. 11) The initial vidal test of the total group showed a counts of 160 titer or more in 60.4% and less than 160 titer in 39.6%, 12) W. B. C. Counts in the uncomplicated group indicated that 32.5% were 6,000/㎣ or less, 47.5% were between 6,000 and 10,000, arid 20.0% were 10,000/㎣ or more. In the complicated group, 37.6% were 6,000/㎣ or less, 25,0% were 6,000-10,000/㎣ and 37.6% were 10,000/㎣ or more. 13) Duration of hospital stay of the patients averaged 6.4 days in the uncomplicated group and 12.7 days in the complicated group. 14) Subdiaphragmatic free air simple X-ray was found in 91.7% of the perforated cases. 15) Duration of antibiotic therapy until an febrile state was attained averaged 4.8 days in the uncomplicated group and 6.5 days in the complicated group. 16) Operative procedures were as follows: one layer simple closure of their perforation with or without debasement in 56.3%, drainage only in 6.3%, small bowel resection with primary anastomosis in 18.8% , externalization in 6.3%, cholecystectomy in 6.3%, The clinical findings of this study suggest the following recommendations. According to Top's report; 1% of typhoid fever patients treated with chlorarnphenicol and 2% of patients treated with other drugs become chronic carriers. Therefore, importance should be given to the strict control of these carriers. Immunization, improvement of sanitation and living standards are all needed for the prevention and treatment of disease, but a more serious problem is a lack of knowledge on the part of patients and their families. Thus it is most urgent to enlighten the citizens about the transmission and hygiene related to contagious disease. Legal restriction of sale of antibiotics at drug stores without a physician's prescription is an urgent matter for public health administrators. An even more important nursing responsibility is the reemphasis on health education both in the clinical setting and in the home.

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