• 제목/요약/키워드: Autonomous oscillation

검색결과 9건 처리시간 0.022초

Saccharomyces cerevisiae의 생물시계와 초단기 대사진동 (Biological Clock and Ultradian Metabolic Oscillation in Saccharomyces cerevisiae)

  • 권정숙;손호용
    • 생명과학회지
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    • 제28권8호
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    • pp.985-991
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    • 2018
  • 생물시계(Biological clock)는 생명체에서 나타나는 반복되는 자율적인 리듬을 말하며, 단일세포는 물론 다세포 생명체의 기본적인 대사와 이에 따른 표현형과 행동을 직접적으로 조절하고 있다. 이러한 생물시계는 동면 리듬, 수면 리듬, 심장박동 리듬 및 짝짓기 노래 리듬 등 매우 다양하며, 24시간 이상의 주기를 infradian rhythm, 24시간 주기를 circadian rhythm, 24시간 이내의 짧은 주기를 ultradian rhythm으로 구분한다. 효모 Saccharomyces cerevisiae는 최소 5종 이상의 반복되는 자율적인 리듬이 알려져 있으며, 이중 일부는 생체시계로 인식되고 있다. 본 리뷰에서는 Saccharomyces cerevisiae의 glycolytic oscillation (T= 1~30분), cell cycle-dependent oscillation (T= 2~16 시간), ultradian metabolic oscillation (T= 15~50분), yeast colony oscillation (T= 수 시간) 및 circadian oscillation (T= 24시간)에 대한 연구 결과를 제시하고, 특히 ultradian metabolic oscillation의 특징, 집단 동조인자(population synchronizer), 동조인자의 조절 기작 및 효모 생물시계의 대사공학 분야의 이용성을 제시하여 효모를 이용한 동적 대사조절 및 생물시계 연구가 가능함을 제시하였다.

가우스 잡음을 고려한 비선형 펄스 변조 시스템의 안정도 분석 (Stability Analysis of Nonlinear Pulse-Modulated System Subject to Gaussian Noise)

  • 강영채
    • 대한전자공학회논문지
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    • 제19권6호
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    • pp.67-79
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    • 1982
  • 가우스 잡음의 출현시 PWM 시스템의 안정도가 연구되었다. 일반 시스템은 종래의 서술 함수 방법을 이용할 때 비선형 소자와 선형 소자로 나누어진다. 등가 어드미턴스 개념이 이 시스템의 비선형 소자의 전달 특성을 구하는데 사용되었다. 이 논문에서는 가우스 잡음만이 존재하는 경우 자기 발진 조건이 유도되었고 그 결과를 컴퓨터 시뮬레이션으로 분석하였다. The stability of general pulse-width modulation system with Gaussian random disturbance was discussed . General system is divided into nonlinear and linear elements using the conventional describing function method. The concept of the equivalent admittance was used to find the transfer characteristic of the nonlinear element of the system. In this paper the self-sustained oscillation condition in the autonomous system was derived and the results was analyzed with computer simulation.

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수중운동체의 강제동요시험 및 포텐셜 계산에 의한 부가질량 추정 (Added Mass of Submerged Bodies Obtained by Forced Oscillation Tests and Numerical Calculations of Potential Flow)

  • 김동진;이경중;권창섭;김연규;박진영;전봉환
    • 대한조선학회논문집
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    • 제59권4호
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    • pp.214-224
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    • 2022
  • It is necessary to estimate manoeuvring characteristics of submerged bodies at the design stage in order to ensure the safe operations. In this study, added mass coefficients in the mathematical model of submerged bodies are estimated by captive model tests and numerical calculations. Two kinds of models, MARIN 'BB2'submarine model and AUV (Autonomous unmanned vehicle) model are utilized in the forced oscillation tests. Compared to BB2 submarine, AUV with cylindrical type hull form shows relatively small added masses in roll, pitch, and yaw directions. Next, numerical calculations based on potential theory are performed under the assumption that viscous effects on inertia forces are negligible. Added masses obtained by numerical calculations are in good agreements with forced oscillation test results. And if slow manoeuvres of submerged bodies are presumed, some of velocity coupled terms can be approximated by combinations of added mass coefficients.

OSCILLATION AND GLOBAL ATTRACTIVITY IN A PERIODIC DELAY HEMATOPOIESIS MODE

  • Saker, S.H.
    • Journal of applied mathematics & informatics
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    • 제13권1_2호
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    • pp.287-300
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    • 2003
  • In this paper we shall consider the nonlinear delay differential equation (equation omitted) where m is a positive integer, ${\beta}$(t) and $\delta$(t) are positive periodic functions of period $\omega$. In the nondelay case we shall show that (*) has a unique positive periodic solution (equation omitted), and show that (equation omitted) is a global attractor all other positive solutions. In the delay case we shall present sufficient conditions for the oscillation of all positive solutions of (*) about (equation omitted), and establish sufficient conditions for the global attractivity of (equation omitted). Our results extend and improve the well known results in the autonomous case.

Regulation of Branched-Chain, and Sulfur-Containing Amino Acid Metabolism by Glutathione during Ultradian Metabolic Oscillation of Saccharomyces cerevisiae

  • Sohn Ho- Yong;Kum Eun-Joo;Kwon Gi-Seok;Jin Ingnyol;Kuriyama Hiroshi
    • Journal of Microbiology
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    • 제43권4호
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    • pp.375-380
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    • 2005
  • Autonomous ultradian metabolic oscillation (T$\simeq$50 min) was detected in an aerobic chemostat culture of Saccharomyces cerevisiae. A pulse injection of GSH (a reduced form of glutathione) into the culture induced a perturbation in metabolic oscillation, with respiratory inhibition caused by $H_2S$ burst pro-duction. As the production of $H_2S$ in the culture was controlled by different amino acids, we attempted to characterize the effects of GSH on amino acid metabolism, particularly with regard to branched chain and sulfur-containing amino acids. During stable metabolic oscillation, concentrations of intra-cellular glutamate, aspartate, threonine, valine, leucine, isoleucine, and cysteine were observed to oscil-late with the same periods of dissolved $O_2$ oscillation, although the oscillation amplitudes and maximal phases were shown to differ. The methionine concentration was stably maintained at 0.05 mM. When GSH (100 $\mu$M) was injected into the culture, cellular levels of branched chain amino acids increased dramatically with continuous $H_2S$production, whereas the cysteine and methionine concentrations were noticeably reduced. These results indicate that GSH-dependent perturbation occurs as the result of the promotion of branched chain amino acid synthesis and an attenuation of cysteine and methionine synthesis, both of which activate the generation of $H_2S$. In a low sulfate medium containing 2.5 mM sulfate, the GSH injections did not result in perturbations of dissolved $O_2$ NAD(P)H redox oscillations without burst $H_2S$ production. This suggests that GSH-dependent perturbation is intimately linked with the metabolism of branched-chain amino acids and $H_2S$ generation, rather than with direct GSH-GSSG redox control.

자율주행 경로 추종 성능 개선을 위한 차량 조향 시스템 특성 분석 (Vehicle Steering System Analysis for Enhanced Path Tracking of Autonomous Vehicles)

  • 김창희;이동필;이경수
    • 자동차안전학회지
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    • 제12권2호
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    • pp.27-32
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    • 2020
  • This paper presents steering system requirements to ensure the stabilized lateral control of autonomous driving vehicles. The two main objectives of a lateral controller in autonomous vehicles are maintenance of vehicle stability and tracking of the desired path. Even if the desired steering angle is immediately determined by the upper level controller, the overall controller performance is greatly influenced by the specification of steering system actuators. Since one of the major inescapable traits that affects controller performance is the time delay of the steering actuator, our work is mainly focused on finding adequate parameters of high level control algorithm to compensate these response characteristics and guarantee vehicle stability. Actual vehicle steering angle response was obtained with Electric Power Steering (EPS) actuator test subject to various longitudinal velocity. Steering input and output response analysis was performed via MATLAB system identification toolbox. The use of system identification is advantageous since the transfer function of the system is conveniently obtained compared with methods that require actual mathematical modeling of the system. Simulation results of full vehicle model suggest that the obtained tuning parameter yields reduced oscillation and lateral error compared with other cases, thus enhancing path tracking performance.

카오스 발진을 위한 RL-광결합기 회로 연구 (A Study on a RL-Photocoupler Circuit for Chaos Oscillation)

  • 정동호;정설희
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 하계종합학술대회 논문집 V
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    • pp.2835-2838
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    • 2003
  • We study the characteristics of oscillating in non-autonomous condition and the conducted noise generation in a RL-photocoupler circuit. This circuit may be shown a period-doubling and a chaos dynamics under any specific conditions of input circuit. But, the relationship between input signals and output signals is different according to the amplitude of driving input voltage. Then, the oscillation noise was analyzed with respect to both the frequency and the amplitude of an external ac signal and do values. The results show that the noise-induced oscillations for falling and rising cycles induced by kick-back effect in an inductor, nonlinear capacitance, nonlinear resistance and charge storage time in a diode and an LED. We also compared the simulation with the experimental results.

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조합공진 영역에서 감쇠의 영향을 고려한 비선형 진동 응답 특성 (Nonlinear Oscillation Characteristics in Combination Resonance Region Considering Damping Effects)

  • 정태건
    • 한국소음진동공학회논문집
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    • 제20권9호
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    • pp.849-855
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    • 2010
  • Damping may change the response characteristics of nonlinear oscillations due to the parametric excitation of a thin cantilever beam. When the natural frequencies of the first bending and torsional modes are of the same order of magnitude, we can observe the one-to-one combination resonance in the perturbation analysis depending on the characteristic parameters. The nonlinear behavior about the combination resonance reveals a chaotic motion depending on the natural frequencies and damping ratio. We can analyze the chaotic dynamics by using the eigenvalue analysis of the perturbed components. In this paper, we derived the equations for autonomous system and solved them to obtain the characteristic equation. The stability analysis was carried out by examining the eigenvalues. Numerical integration gave the physical behavior of each mode for given parameters.

Frequency Tracking of Resonance Frequency Variation of L-C Circuits for Wireless Energy Transmission to Medical Devices in Human Organs

  • Gimm, Yoon-Myoung;Ju, Young-Jun;Lee, Yu-Ri;Lee, Dong-Yeol;Wang, Jong-Wook
    • Journal of electromagnetic engineering and science
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    • 제11권4호
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    • pp.298-303
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    • 2011
  • A capsular endoscope (CE) for inspection of the large intestine requires a motor for backward navigation against the autonomous travel in the intestine. This study proposes an HF power system for generating a magnetic field and for delivering wireless power to the internal or implanted medical devices. The magnetic field is generated by a wound coil (L) around a wooden frame, and the current is driven to the coil through a resonating capacitor (C). The characteristics of the resonance frequency shifting of the L-C series circuit are analyzed. A stable magnetic field intensity in the field coil is maintained by a specially designed frequency tracking system that automatically follows the L-C resonance frequency. Testing confirmed that the oscillation system tracks well the parameter changes of the electric components caused by the operating conditions or environmental variations.