• 한국농림기상학회지
• /
• 제8권4호
• /
• pp.270-274
• /
• 2006

본 연구에서 고안 설계한 적설 관측용 수위 센서는 야외에서 일 변화량은 0.1 mm 내외의 적은 양의 오차를 기록하여 강설관측 센서로 적합한 것으로 판명되었으며, 실내 검정 결과 기상청에서 요구하고 100 mm의 강수 검정범위에 대해서 1%이하의 신뢰성 있는 검정결과를 나타내어 강설량 관측에 적합한 것으로 판명되었다. 또한 $-20^{\circ}C$의 테스트에서도 0.1 mm에 해당하는 아주 작은 변화 값을 타나내어 겨울철 야외환경에도 적합한 것으로 판명되었다. 깔때기가 없으며 수수구의 크기에 제한을 받지 않는 새로운 강수 관측구조는 적은 양의 강설관측이 가능하여 겨울철 예보에 필요한 레이다. 영상과 위성 영상에 의한 강설 연구와 해석에 많은 도움을 줄 수 있을 것이다. 또한 적설상당수량 관측이 가능하여 수자원 분야의 연구에도 많은 도움이 될 수 있다. 부동액을 사용하므로 고체 상태의 강설에 대해서 직접 관측이 가능하여 강설 관측에 있어 문제점으로 지적이 되고 있는 신적설 관측의 어려움을 해결할 수 있으며, 추후 야외 관측용 모델을 제작하여 야외 환경에서 여타 장비들과 비교 실험을 통해서 성능을 검정하고 개선할 계획이다.

• 한국지능시스템학회논문지
• /
• 제23권5호
• /
• pp.436-443
• /
• 2013

본 논문에서는 중량물을 들어 올리는 작업자를 돕기 위한 와이어 구동식 권양 시스템의 제어기와 제어기 설계를 위한 작업자 모델링을 제시한다. 와이어 구동식 중량물 권양 시스템은 사람이 전체 제어루프에 포함된 인간지원시스템의 일종이다. 사람의 제어 특성 모델과 물건을 들어 올리는 작업자의 힘을 덜어주어야 하는 요구조건을 고려한 퍼지제어기 설계 방식을 제안한다. 또한 권양 초기 구간에서 중량물의 무게를 자체적으로 측정하여 구동될 수 있는 방식도 소개한다. 마지막으로 성능 검증을 위해 실험을 통하여 제어기의 무게 측정의 정확도를 분석하고 중량물을 작업자가 작은 힘으로 편하게 들어 올릴 수 있는지 그 결과를 분석한다.

• 한국항행학회논문지
• /
• 제25권1호
• /
• pp.68-77
• /
• 2021

본 논문에서는 높은 동특성 환경에서 동작이 가능한 GPS/MEMS IMU 통합항법 수신모듈을 설계 및 제작하고, 그 결과를 확인하였다. 설계한 모듈은 RF 수신부, 관성측정부, 신호처리부, 상관기, 항법 S/W로 구성된다. RF 수신부는 저잡음증폭, 주파수 변환, 필터링, 자동이득조절 기능을 수행하고, 관성측정부는 3축 자이로스코프, 가속도계, 지자기센서가 적용된 MEMS급 IMU로부터 측정 데이터를 수집하여 항법S/W로 전달하는 인터페이스를 제공한다. 신호처리부 및 상관기는 FPGA 로직으로 구현하여 필터링 및 상관 값 계산을 수행하고, FPGA 내부 CPU를 사용하여 위성항법, 통합항법 S/W를 구현하였다. 제작된 모듈의 크기는 95.0 × 85.0 × 12.5 mm 이고, 무게는 110g을 확인하였으며, 동적성능 1200m/s, 가속도 10g의 환경에서 규격 이내의 항법정확도 성능을 확인하였다.

• 한국토양비료학회지
• /
• 제43권3호
• /
• pp.374-383
• /
• 2010

본 연구에서는 기상조건에 영향을 받지 않고 레이더산란 측정을 할 수 있는 X-band 안테나 기반 자동관측 시스템을 구축하였다. 이 시스템을 이용하여 벼 생육시기에 따른 편파별 후방산란계수 변화와 벼 생육인자 변화를 관측하고, 후방산란계수와 벼 생육인자와의 관계를 분석을 통해 최적조건의 후방산란계수를 이용한 벼 생육을 추정하였다. 벼 생육시기에 후방산란계수 변화를 관측해 본 결과 생육초기에는 VV-편파가 HH, HV/VH-편파 보다 후방산란계수가 높게 나타났고, 모든 편파별 후방산란계수가 벼 유수형성기 (7월 말경)까지 증가하다가 그 후 감소 한 후 9월 초순이후 다시 증가하는 dual-peak 현상을 뚜렷이 나타났다. 동시에 생육시기에 따른 생체중, 이삭 건물중, 엽면적지수, 초장 등 벼 생육인자들의 생육 변화를 관측해 보았는데 생체중, 엽면적지수, 초장은 6월 중순부터 7월 하순까지 편파별 후방산란계수와의 변화 경향이 비슷하게 나타났고, 이삭 건물중의 경우 특히 VV-편파 후방산란계수가 9월 초순에서 10월 초순까지 변화 경향이 동일하게 나타났다. 편파별 후방산란계수와 벼 생육인자와의 상관관계를 분석한 결과 엽면적지수, 생체중은 6월 중순 (DOY 168)부터 7월 하순 (DOY 209) 시기에 HH-편파 후방산란 계수와 상관관계가 높았고, 초장은 같은 시기에 VV-편파 후방산란계수와 관계가 높게 나타났다. 이삭 건물중의 경우 벼 출수기가 끝나고 결실기로 접어드는 9월 초순 (DOY 244) 부터 10월 초순 (DOY 276) 시기에 VV-편파 후방산란계수와 상관관계가 높게 나타났다. 이 결과를 바탕으로 벼 생육인자와 상관이 높게 나타난 편파별 후방산란계수를 이용하여 벼 생육을 추정하였다. 엽면적지수는 HH-편파 후방산란계수를 이용하여 2007년도 실측값과 2008년도 추정 경험 모형을 비교해본 결과 비교적 오차가 작았고 (RMSE=0.43), 상관관계가 높은 HH-편파 후방산란계수를 이용하여 2007년도 생체중 실측값과 생체중 추정 모형 (2008년도)을 비교해 본 결과 RMSE가 41.0 g $m^{-2}$ 으로 비교적 작은 오차를 보여 생체중 추정 모형의 유효성이 높다는 것이 증명되었다. 또한 초장의 경우 실측값 (2007년)과 초장 추정 모형 (2008년)을 비교 분석한 결과 오차 범위가 비교적 작게 나타났고 (RMSE=6.93 cm), VV-편파 후방산란계수를 이용해 얻은 이삭 건물중 추정 경험 모형 (2008년도)과 2007년도 이삭 건물중 실측값과의 관계를 통해 추정식을 검증한 결과 RMSE=0.35 g/m2 을 보여 이삭 건물중 추정모형의 유효성이 높다는 것이 증명되었다. 본 연구결과에서는 Kim et al. (2009)이 일정한 간격을 두고 수동조건으로 관측한 결과와 비교해서 벼 생육시기에 따른 편파별 후방산란계수 변화 경향이 뚜렷하게 나타났고, 이 후방산란계수를 이용하여 벼 생육인자와의 관계 및 추정 결과에서도 기존 결과보다 상관관계 및 생육추정 모형 유효성이 높게 나타났다. 본 연구 결과를 통해 X-band 산란계 자동측정 시스템을 이용하여 벼 생육을 예측 할 수 있음을 확인하였다.

• 전자공학회논문지
• /
• 제50권11호
• /
• pp.226-233
• /
• 2013

본 논문에서는 해태를 자동적으로 가공 처리하는 건조 장치에서, 해태의 두께측정 및 조절하는 장치에 관한 것으로서, 해태를 자동적으로 가공 처리하는 건조 장치에 있어서, 김과 물의 혼합된 상태로 일정한 크기의 형상을 가진 틀에 소정의 양을 투입해 물과 김을 분리하여, 목적하는 김의 크기와 두께(무게)를 결정짓는 공정에, 일정한 광원을 발생할 LED Lamp 와 영상을 검출하는 Vision Sensor(카메라)등을 구비하고, 이들의 영상 상태 값 들을 임베디드 컴퓨터에 실시간 전송하고, 함께 내장된 측정 및 제어 목적의 응용 프로그램에 의하여, 각각의 해당 채널의 측정값을 별도로 구비된 모니터에 표시함은 물론 각각의 해당 채널의 엑츄에이터에 서보 신호를 전송해, 기 설정된 목적의 기능이 가능 하도록 한 해태(김)의 두께를 측정하여 조절하는 장치에 관한 것이다. 본 논문의 해태(김)건조 장치에서 해태(김)의 두께측정 및 조절하는 장치는, 기존 작업자의 경험에 의지하여 직접 김의 두께조절 레버를 수동으로 조작하여 김의 두께를 조절하는 방식에서 탈피하여, 각각의 채널별 조절 레버에 엑츄에이터를 설치하여 상대적으로 품질 향상을 할 수 있도록 하였다. 또한 기존에 비해 생산성 향상 및 노동력 절감 효과도 있다.

• 농업생명과학연구
• /
• 제51권6호
• /
• pp.137-144
• /
• 2017

A diverse of recommendation has been made for the structure and management of dairy cows, despite demanding research, the relationship between lactation number and various factors is yet to be established. The present study was aimed to investigate the covariance among lactation number, growth performance, calving interval, and milk production was considered to increase an efficiency of selection schemes and to manage more efficiently Holstein dairy cows that have been raised on small-scale family farms in Republic of Korea. For that purpose, the data were observed from 850 Holstein dairy cows, which a total of 3929 milking, since April 2016 - January 2017. We measured the body weight, height, age, calving interval, and milk production of the each dairy cow. Also, information about the date of lactation, calving interval, and milk production was recorded using an automatic milking system(AMS) with identification numbers. Milk production was calculated per udder quarter in the AMS. Our study results showed the increased average body weight(p>0.05) in 1, 2, 3, and $4^{th}$ lactating dairy cows and afterwards, we noticed the tendency on the average body weight(p<0.05) per lactation progressed. There was no significant difference noticed on height measurement of dairy cows. From the processing data of 850 Holstein dairy cows, the lactation number 1 and 7 had a greater calving interval with significantly lowered milk production, and the lactation number 2, 3, 4, 5, and 6 had significantly lowered the calving interval(p<0.05) with a greater milk production. From our study results, we evidenced that there is a significant relationship between the lactation number, growth performance, calving interval, and milk yield, and the maximum production of milk occurring in the $3^{rd}$ and $4^{th}$ lactation dairy cows. The achieved results from this study can be used by the small-scale farmers to encourage the structure and management of growth performance, calving interval, and milk yield in Holstein dairy cows in Korea.

• 한국버섯학회지
• /
• 제17권4호
• /
• pp.211-217
• /
• 2019

최근 ICT기반 스마트팜이 급속도로 증가추세이다. 버섯의 생육환경요인은 온도, 습도, CO₂, 광이 주 요인이지만 그동안 온도 위주의 자동제어가 사용되어왔다. 큰느타리버섯의 생육환경 조절은 온도는 자동제어하지만 가습과 환기는 경험을 기준으로 한 타이머 사용을 하고 있었다. 이에 본 연구에서는 온도, 습도, 환기까지 자동제어를 통해 큰느타리버섯의 1세대 스마트팜 모델을 설정하기 위한 시험을 진행하였다. 환경제어시스템 및 모니터링 장비를 설치 한 후 기존의 방법으로 재배하고 있는 상태에서 생육실의 조건과 자실체의 생육조사를 실시하였으며 그 결과를 소개하고자 한다. A농가의 경우 온도는 약 17℃에서 발이시키고 자실체 생육기에는 약 16도로 관리하였다. 습도는 초기 95%로 유지하다가 초발이 이후에는 가습을 하지 않는 경향이었다. CO₂ 관리는 센서도 없었으며 갓과 대의 모양을 보면서 관행적으로 환기하고 있었고 700 ppm에서 최고 2,500 ppm까지 유지하는 경향이었다. 이 농가의 자실체 품질은 평균 개체중 125 g, 대굵기 53 mm, 대길이/대굵기 비율은 1.8, 갓직경/대굵기 1.25 수준으로 A등급(특품)~B등급(상품) 사이에 해당하였다. B농가의 경우는 온도는 약 19~17℃에서 발이시키고 자실체 생육기에는 약 17℃로 관리하였고 생육후기에는 13~15℃였다. 습도는 83~95%로 육안관찰하면서 관행적으로 조절하는 경향이었다. CO₂ 관리는 센서는 있었으나 제어는 하지 않았고 갓과 대의 모양을 보면서 관행적으로 환기하고 있었고 640 ppm에서 최고 4,500 ppm까지 유지하는 경향이었다. 이 농가의 자실체 형태는 평균 개체중 102 g, 대굵기 48 mm, 대길이/대굵기 비율은 2.2, 갓직경/대굵기 1.2 수준이었다. 이러한 결과는 환경조건 특히 CO₂ 농도에 따라 큰느타리버섯의 품질이 결정됨을 알 수 있었으며 A농가의 환경조절 방법을 개선하면서 DB화하면 정밀한 스마트팜 모델로 적용할 수 있을 것으로 기대된다.

• 대한원격탐사학회지
• /
• 제27권2호
• /
• pp.191-201
• /
• 2011

본 연구에서는 다편파 레이더 산란계 자동 측정시스템 이용하여 콩 생육변화를 관측하고 레이더 시스템에서 얻어진 후방산란계수과 콩 생육인자들과의 관계분석을 통하여 콩 생육추정 가능성을 모색하고자 하였다. 2010년도 농촌진흥청 국립식량과학원 연구지역에 다편파 레이더 산란계 관측시스템 (L, C, X-밴드 안테나, 네트워크분석기, RF switch, 입사각 $40^{\circ}$)을 구축하고 콩 파종시기에서 수확기까지 10분단위로 콩 생육변화를 자동 측정하였다. 모든 안테나 밴드, 편파에서 콩 생육초기 (6월초~7월 중순)에는 VV-편파가 HH-, HV-편파보다 후방산란계수가 높게 나타났고, 그 이후 HH-편파와 다른 편파들 간의 cross-over 현상이 일어났는데 그 시기는 L-밴드가 7월 20일 (DOY 200), C-, X-밴드의 경우에는 7월 30일 (DOY 210)로 밴드에 따라 차이를 보였다. 모든 밴드 및 편파에서 9월 29일 (DOY 271)까지 후방산란계수가 증가하다가 그 이후 감소하였고 특히 종실비대기 (DOY 277, R6) 이후 감소폭이 크게 나타났는데 이 현상은 콩 생육인자 (초장, 엽면적지수, 건물중 등)변화와 일치하였다. 밴드에 따른 후방산란계수와 콩 생육인자들과의 관계를 분석한 결과 L-밴드 HH-편파에서 LAI ($r=0.93^{***}$), 초장 ($r=0.95^{***}$), 건물중 ($r=0.94^{***}$), 꼬투리중 ($r=0.92^{***}$)등 콩 생육인자들과의 상관계수가 가장 높게 나타났고 이에 비해 X-밴드 편파에서는 콩 생육인자들과의 상관계수가 상대적으로 낮게 나타났다. 후방산란계수 (L-밴드 HH-편파)를 이용하여 콩 생육인자 추정을 위한 회귀식을 작성하였다.

• 대한방사선치료학회지
• /
• 제32권
• /
• pp.7-15
• /
• 2020

목 적: 현대 방사선치료기술에서 종양표적위치 및 정상장기에 정확한 선량을 전달하기 위해 여러 방법의 영상유도방사선치료(Image Guided Radiation Therapy, IGRT)가 사용되고 있으며 그 중 선형가속기에 장착된 CBCT(Cone Beam Computed Tomography, CBCT)와 이외 장치인 ExacTrac(ExacTrac X-ray System)이 있다. 두 시스템을 비교한 이전 연구들에서는 Offline-review 이용하여 후향적으로 팬텀 및 환자의 Set-up 오차를 분석하거나 X, Y, Z 축과 하나의 회전방향(Couch Rotation)으로만 연구되어졌다. 본 연구에서는 Head and Neck Cancer 환자를 대상으로 CBCT와 ExacTrac을 이용하여 한 치료중심센터에서 각각 6 DoF(Degree Of Freedom) IGRT를 시행한 후, 두 IGRT 장비에서 나타난 팬텀 및 환자의 Set-up 오차, 환자 Set-up에 걸리는 시간, 노출 방사선량의 비교를 통해 유용성을 평가하고자 한다. 대상 및 방법: Rando Phantom을 이용하여 환자 움직임을 배제한 상태의 Set-up 오차 평가와 Head and Neck Cancer 환자의 Set-up 오차 값 두 가지 경우로 나누어 획득하였다. 노출 방사선량 평가는 유리선량계로 하였다. 환자 Set-up 후 IGRT 시행하는데 소요되는 시간을 평가하기 위해 Head and Neck Cancer 환자 11명을 대상으로 하였다. 총 치료기간동안 환자 당 평균 10회의 CBCT와 ExacTrac 영상을 동시에 얻었고, 관심영역지정(Region Of Interest, ROI) 설정 후 6D 온라인 자동위치교정(Online Automatching) 값의 차를 6개의 축(Translation group: SI, AP, LR; Rotation group: Pitch, Roll, Rtn)으로 각각 계산하였다. 결 과: Phantom과 환자에서 Set-up 오차는 Translation group에서 1mm 미만, Rotation group에서 1.5° 미만의 차이가 보였으며, Rtn 값을 제외한 다른 모든 축의 RMS 값이 1mm, 1° 미만으로 나타났다. 각 시스템에서 최종적으로 Set-up 오차 교정까지 걸리는 시간은 CBCT를 이용한 IGRT에서는 평균 256±47.6sec, ExacTrac을 이용 시 평균 84±3.5sec로 각각 나타났다. 1회 치료 당 IGRT에 의한 방사선 노출선량은 Head and Neck 부위 7곳의 측정위치 중 Oral Mucosa에서 CBCT와 ExacTrac이 각각 2.468mGy, 0.066mGy로 상대적으로 ExacTrac에 비해 피폭선량이 37배 높게 측정되었다. 결 론: CBCT와 ExacTrac 두 시스템 간의 6D 온라인 자동위치교정을 통해 Set-up 오차는 두 시스템의 자체적인 Systematic error 뿐 아니라, 환자 움직임(Random error)를 포함한 Set-up 오차가 1mm, 1.02° 미만으로 나타났다. 이는 본원에서 Head and Neck IMRT 치료 시 PTV Margin이 3mm이라는 것을 고려했을 때, 이 오차범위는 합리적으로 사료된다. 하지만 치료기간 동안 환자체중변화로 인한 따른 표적, 손상위험장기의 변화를 고려했을 때 CBCT와 적절히 병용하여 사용하는 것이 좋을 것으로 사료된다.

• 대한의용생체공학회:의공학회지
• /
• 제6권2호
• /
• pp.1-8
• /
• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.