• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.2C
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• pp.119-125
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• 2011

Start This paper analyzes the propagation characteristics of acoustic signals in indoor environments, which is applicable to indoor positioning system. Indoor stereo sound system is generally valid within $25m^2$. So it is not possible to apply prevalent sound propagation characteristic to indoor positioning system because the prevalent acoustic signals propagation characteristic is defined under free space condition. Therefore, in this paper, we present the propagation characteristics of acoustic signals in indoor environments considering the free space propagation characteristic as well as room characteristic such as humidity, temperature, absorption of atmosphere and so on. To verify the designed propagation model of indoor acoustic signals, this paper presents the propagation characteristics of decreasing sinusoidal signals whose frequencies ate from 1kHz to 20kHz in anechoic room. In addition, this paper also presents the propagation characteristics of decreasing sinusoidal signals which have multiple frequencies.

• Journal of Korean Tunnelling and Underground Space Association
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• v.4 no.1
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• pp.27-35
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• 2002

For the excavation of the rock, blast method is put into operation in most of the construction site in Korea. In comparison to other methods of excavation, blast method has many merits such as improvement in efficiency in operation, reducement of operation period, and etc. However, blast operation also creates much loss due to the blast vibration, noise, and fly rocks. Thus, in this study, we have examined main features, rock fragmentation effect and the application of plasma method the one of shallow vibration method. In this study, the attenuation exponent of blast method operated in the site was 1.39~1.40 and that of the plasma method was analysed to be 1.45~2.23. From the location where the distance between excavation location and observation location was over 15 m, most of excavation vibration were measured to be less than 0.2 kine(cm/sec), which is also the allowed standard value of sensitive buildings, such as cultural assets and computer facilities. According to the result of FFT(Fast Fourier Transform) analysis, the frequency measured through blast method in this site was 30~50 Hz and the frequency of plasma method ranges in between 30~130 Hz.

• Molecules and Cells
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• v.41 no.5
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• pp.476-485
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• 2018

Although tectorigenin (TG), a major compound in the rhizome of Belamcanda chinensis, is conventionally used for the treatment of inflammatory diseases, its effects on osteogenesis and osteoclastogenesis have not been reported. The objective of this study was to investigate the effects and possible underlying mechanism of TG on in vitro osteoblastic differentiation and in vivo bone formation, as well as in vitro osteoclast differentiation and in vivo bone resorption. TG promoted the osteogenic differentiation of primary osteoblasts and periodontal ligament cells. Moreover, TG upregulated the expression of the BMP2, BMP4, and Smad-4 genes, and enhanced the expression of Runx2 and Osterix. In vivo studies involving mouse calvarial bone defects with ${\mu}CT$ and histologic analysis revealed that TG significantly increased new bone formation. Furthermore, TG treatment inhibited osteoclast differentiation and the mRNA levels of osteoclast markers. In vivo studies of mice demonstrated that TG caused the marked attenuation of bone resorption. These results collectively demonstrated that TG stimulated osteogenic differentiation in vitro, increased in vivo bone regeneration, inhibited osteoclast differentiation in vitro, and suppressed inflammatory bone loss in vivo. These novel findings suggest that TG may be useful for bone regeneration and treatment of bone diseases.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.12A
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• pp.941-949
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• 2011

In a cooperative communication system with a source node and multiple relays equipping single antenna and a destination node equipping multiple antennas, the selective cooperative spatial multiplexing scheme can obtain spatial multiplexing gain and additional selection diversity gain. But it can degrade a bit error rate performance because some received symbols forwarded from particular relays may be lost by attenuation due to path-loss. We propose a relay and transmission mode selection scheme which selects minimum number of multiple relays having the channel capacity larger than a given data rate and transmission mode which switches spatial multiplexing and spatial diversity mode in cooperation phase to enhance the bit error rate performance. The proposed scheme achieves 1.5~2dB gain at the low SNR range compared with the conventional scheme by obtaining additional spatial diversity gain.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.12
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• pp.1359-1364
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• 2012

The C-band semi-lumped lowpass filter with broad stopband and compact size characteristic using chip inductor is proposed. To provide an additional attenuation pole in stopband by SRF, a separable inductor is added to proposed structure, and it has broad stopband characteristic. The third order elliptic function lowpass filter with chip inductor(L: 9.1 nH, SRF: 5.5 GHz, Q: 25) has insertion loss of 0.38 dB, cutoff frequency of 920 MHz, broad stopband(below 20 dB) of 1.43~7.8 GHz and the size is reduced 37.4 % compared to distributed inductor.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.9
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• pp.2298-2306
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• 2014

In this paper, we propose an open loop power control algorithm to control transmission power of the On-The-Move(OTM) Satcom terminal in GEO satellite communication environment. The proposed algorithm identifies the current channel state restricted by an obstacle or an antenna depointing loss based on the received beacon signal strength. On the basis of the determined signal attenuation causes, the OTM Satcom terminal turns off the RF output when an antenna tracking is failed. If the OTM Satcom terminal experiences a channel blockage by an obstacle, the terminal spreads the transmit data to increase data reception probability. To evaluate the performance of the proposed algorithm, we compare an adjacent satellite interference level and an outage probability. The results show the performance of the proposed algorithm is better than that of the conventional algorithm.

• The Journal of Korean Society for Radiation Therapy
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• v.10 no.1
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• pp.69-77
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• 1998

When a high energy photon beam is used to treat lesions located in the upper respiratory air passages or in maxillary sinus, the beams often must traverse an air cavity before it reaches the lesion. Because of this traversal of air, it is not clear that the surface layers of the lesion forming the air-tumor tissue interface will be in a state of near electronic equilibrium; if they are not, underdosing of these layers could result. Although dose corrections at large distances beyond an air cavity are accountable by attenuation differences, perturbations at air-tissue interfaces are complex to measure or calculate. This problem has been investigated for 4MV and 10MV X-ray beams which are becoming widely available for radiotherapy with linear accelerator. Markus chamber was used for measurement with variouse air cavity geometries in X-ray beams. Underdosing effects occur at both the distal and proximal air cavity interface. The magnitude depended on geometry, energy, field sizes and distance from the air-tissue interfaces. As the cavity thickness increased, the central axis dose at the distal interface decreased. Increasing field size remedied the underdosing, as did the introduction of lateral walls. Fellowing a $20{\times}2{\times}2\;cm^3$\;air\;cavity,\;4{\times}4\;cm\;field\;there\;was\;an\;11.5\%\;and\;13\%\;underdose\;at\;the\;distal\;interface,\;while\;a\;20{\times}20{\times}2\;cm^3\;air\;cavity\;yielded\;a\;24\%\;and\;29\%$ loss for the 4MV and 10MV beams, respectively. The losses were slightly larger for the 10MV beams. The measurements reported here can be used to guide the development of new calculation models under non-equilibrium conditions. This situation is of clinical concern when lesions such as larynx and maxillary carcinoma beyond air cavities are irradiated.

• Molecules and Cells
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• v.43 no.1
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• pp.34-47
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• 2020

The circadian clock regulates various physiological processes, including bone metabolism. The nuclear receptors Reverbs, comprising Rev-erbα and Rev-erbβ, play a key role as transcriptional regulators of the circadian clock. In this study, we demonstrate that Rev-erbs negatively regulate differentiation of osteoclasts and osteoblasts. The knockdown of Rev-erbα in osteoclast precursor cells enhanced receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation, as well as expression of nuclear factor of activated T cells 1 (NFATc1), osteoclast-associated receptor (OSCAR), and tartrate-resistant acid phosphatase (TRAP). The overexpression of Rev-erbα leads to attenuation of the NFATc1 expression via inhibition of recruitment of c-Fos to the NFATc1 promoter. The overexpression of Rev-erbα in osteoblast precursors attenuated the expression of osteoblast marker genes including Runx2, alkaline phosphatase (ALP), bone sialoprotein (BSP), and osteocalcin (OC). Rev-erbα interfered with the recruitment of Runx2 to the promoter region of the target genes. Conversely, knockdown of Rev-erbα in the osteoblast precursors enhanced the osteoblast differentiation and function. In addition, Rev-erbα negatively regulated osteoclast and osteoblast differentiation by suppressing the p38 MAPK pathway. Furthermore, intraperitoneal administration of GSK4112, a Rev-erb agonist, protects RANKL-induced bone loss via inhibition of osteoclast differentiation in vivo. Taken together, our results demonstrate a molecular mechanism of Rev-erbs in the bone remodeling, and provide a molecular basis for a potential therapeutic target for treatment of bone disease characterized by excessive bone resorption.

• Molecules and Cells
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• v.42 no.3
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• pp.218-227
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• 2019

This study was designed to determine the effects of the long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) on vascular smooth muscle cell (VSMC) apoptosis and extracellular matrix (ECM) disruption in a murine abdominal aortic aneurysm (AAA) model. After injection of PVT1-silencing lentiviruses, AAA was induced in Apolipoprotein E-deficient ($ApoE^{-/-}$) male mice by angiotensin II (Ang II) infusion for four weeks. After Ang II infusion, mouse serum levels of pro-inflammatory cytokines were analysed, and aortic tissues were isolated for histological, RNA, and protein analysis. Our results also showed that PVT1 expression was significantly upregulated in abdominal aortic tissues from AAA patients compared with that in controls. Additionally, Ang II treatment significantly increased PVT1 expression, both in cultured mouse VSMCs and in AAA murine abdominal aortic tissues. Of note, the effects of Ang II in facilitating cell apoptosis, increasing matrix metalloproteinase (MMP)-2 and MMP-9, reducing tissue inhibitor of MMP (TIMP)-1, and promoting switching from the contractile to synthetic phenotype in cultured VSMCs were enhanced by overexpression of PVT1 but attenuated by knockdown of PVT1. Furthermore, knockdown of PVT1 reversed Ang II-induced AAA-associated alterations in mice, as evidenced by attenuation of aortic diameter dilation, marked adventitial thickening, loss of elastin in the aorta, enhanced aortic cell apoptosis, elevated MMP-2 and MMP-9, reduced TIMP-1, and increased pro-inflammatory cytokines. In conclusion, our findings demonstrate that knockdown of lncRNA PVT1 suppresses VSMC apoptosis, ECM disruption, and serum pro-inflammatory cytokines in a murine Ang II-induced AAA model.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.13 no.6
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• pp.483-488
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• 2020

In recent years, the demand for wireless devices incorporating several wireless communication systems into one has been increasing in order to provide services that meet the diverse needs of consumers. Wireless devices consisting of various wireless communication systems require many frequency fixed filters. A frequency tunable filter can replace a number of frequency fixed filters in the wireless devices. If a frequency tunable filter is used in wireless systems, the system can be configured more efficiently. In this paper, a 3-pole frequency tunable BPF(bandpass filter) operating in the frequency band of 800 ~ 2400MHz is designed. In order to widen the operating frequency band, a tuning screw is designed to have a step and a linear motor is used to facilitate the adjustment of the tuning screw. The implemented frequency tunable BPF operates in the designed frequency range and has the maximum insertion loss of 2.82dB in the channel band and the minimum attenuation of 18.7dB at ± 50MHz frequency offset from the center frequency of the band.