• Title/Summary/Keyword: Association study

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A Short History of the Genome-Wide Association Study: Where We Were and Where We Are Going

  • Ikegawa, Shiro
    • Genomics & Informatics
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    • v.10 no.4
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    • pp.220-225
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    • 2012
  • Recent rapid advances in genetic research are ushering us into the genome sequence era, where an individual's genome information is utilized for clinical practice. The most spectacular results of the human genome study have been provided by genome-wide association studies (GWASs). This is a review of the history of GWASs as related to my work. Further efforts are necessary to make full use of its potential power to medicine.

Genome-Wide Association Study of Hepatitis in Korean Populations

  • Hong, Youngbok;Oh, Sejong
    • Genomics & Informatics
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    • v.12 no.4
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    • pp.203-207
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    • 2014
  • Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong and Ansan cohort data. About 300,000 single-nucleotide polymorphisms and 20 epidemiological variables were analyzed. We did not find any meaningful significant single nucleotide polymorphisms, but we confirmed the influence of major epidemiological variables on hepatitis.

The Impact of Logo Design on Brand Association and Consumer Emotions (로고디자인이 브랜드 연상과 소비자 감성에 미치는 영향에 관한 연구)

  • Kim, Jeong-Yeol;Lee, Jae-Yeon
    • Journal of Industrial Convergence
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    • v.5 no.2
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    • pp.33-51
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    • 2007
  • environmental has given rise to a world where consumer persue satisfaction in quality and quantity of products. From this point of view, a study of the impact of logo design on brand association and consumer emotions is very important and useful. For this study, we investigate on the basis of preceding studies. Finally, it is thought that it will be necessary to conduct a more specific study on the relation between brand association and consumer emotions.

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The Effect of Corporate Association on the Perceived Risk of the Product (소비자의 제품 지각 위험에 대한 기업연상과 효과: 지식과 관여의 조절적 역활을 중심으로)

  • Cho, Hyun-Chul;Kang, Suk-Hou;Kim, Jin-Yong
    • Journal of Global Scholars of Marketing Science
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    • v.18 no.4
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    • pp.1-32
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    • 2008
  • Brown and Dacin (1997) have investigated the relationship between corporate associations and product evaluations. Their study focused on the effects of associations with a company's corporate ability (CA) and its corporate social responsibility (CSR) on consumers' product evaluations. Their study has found that both of CA and CSR influenced product evaluation but CA association has a stronger effect than CSR associations. Brown and Dacin (1997) have, however, claimed that there are few researches on how corporate association impacts product responses. Accordingly, some of researchers have found the variables to moderate or to mediate the relationship between the corporate association and the product responses. In particular, there has been existed a few of studies that tested the influence of the reputation on the product-relevant perceived risk, but the effects of two types of the corporate association on the product-relevant perceived risk were not identified so far. The primary goal of this article is to identify and empirically examine some variables to moderate the effects of CA association and CSR association on the perceived risk of the product. In this articles, we take the concept of the corporate associations that Brown and Dacin (1997) had proposed. CA association is those association related to the company's expertise in producing and delivering its outputs and CSR association reflected the organization's status and activities with respect to its perceived societal obligations. Also, this study defines the risk, which is the uncertainty or loss of the product and corporate that consumers have taken in a particular purchase decision or after having purchased. The risk is classified into product-relevant performance risk and financial risk. Performance risk is the possibility or the consequence of a product not functioning at some expected level and financial risk is the monetary loss one perceives to be incurring if a product does not function at some expected level. In relation to consumer's knowledge, expert consumers have much of the experiences or knowledge of the product in consumer position and novice consumers does not. The model tested in this article are shown in Figure 1. The model indicates that both of CA association and CSR association influence on performance risk and financial risk. In addition, the effects of CA and CSR are moderated by product category knowledge (product knowledge) and product category involvement (product involvement). In this study, the relationships between the corporate association and product-relevant perceived risk are hypothesized as the following form. For example, Hypothesis 1a($H_{1a}$) is represented that CA association has a positive influence on the performance risk of consumer. Also, the hypotheses that identified some variables to moderate the effects of two types of corporate association on the perceived risk of the product are laid down. One of the hypotheses of the interaction effect is Hypothesis 3a($H_{3a}$), it is described that consumer's knowledges of the product moderates the negative relationship between CA association and product-relevant performance risk. A field experiment was conducted in order to examine our model. The company tested was not real but imagined to meet the internal validity. Water purifiers were used for our study. Four scenarios have been developed and described as the imaginary company: Type A with both of superior CA and CSR, Type B with superior CSR and inferior CA, Type C with superior CA and inferior CSR, and Type D with both inferior of CA and CSR. The respondents of this study were classified into four groups. One type of four scenarios (Type A, B, C, or D) in its questionnaire was given to the respondent who filled out questions. Data were collected by means of a self-administered questionnaire to the respondents, chosen in convenience. A total of 300 respondents filled out the questionnaire but 207 were used for further analysis. Table 1 indicates that the scales in this study are reliable because the range of coefficients of Cronbach's $\alpha$ are from 0.85 to 0.92. The composite reliability is in the range of 0,85 to 0,92 and average variance extracted is in 0.72-0.98 range that is higher than the base level of 0.6. As shown in Table 2, the values for CFI, NNFI, root-mean-square error approximation (RMSEA), and standardized root-mean-square residual (SRMR) are acceptably close to the standards suggested by Hu and Bentler (1999):.95 for CFI and NNFI,.06 for RMSEA, and.08 for SRMR. We also tested discriminant validity provided by Fornell and Larcker (1981). As shown in Table 2, we found strong evidence for discriminant validity between each possible pair of latent constructs in all samples. Given that these batteries of overall goodness-of-fit indices were accurate and that the model was developed on theoretical bases, and given the high level of consistency across samples, this enables us to proceed the previously defined scales. We used the moderated hierarchical regression analysis to test the influence of the corporate association(CA and CSR associations) on product-relevant perceived risk(performance and financial risks) and to identify the variables moderating the relationship between the corporate association and product-relevant performance risk. In this study, dependent variables are performance and financial risk. CA and CSR associations are described the independent variables. The moderating variables are product category knowledge and product category involvement. The results are, as expected, found that CA association has statistically a significant influence on the perceived risk of the product, but CSR association does not. Product category knowledge and involvement moderate the relationship between the CA association and the perceived risk of the product. However, the effect of CSR association on the perceived risk of the product is not moderated by the consumers' knowledge and involvement. For this result, it is necessary for a corporate to inform its customers CA association more than CSR association so that they could be felt to be the reduction of the perceived risk. The important theoretical contribution of this research is the meanings that two types of corporate association that Brown and Dacin(1997), and Brown(1998) have proposed replicated the difference of the effects on product evaluation. According to Hunter(2001), it was an important affair to accomplish the validity of a particular study and we had to take about ten studies to deduce a strict study. Next, there is the contribution of the this study to find that the effects of corporate association on the perceived risk of the product are varied by the moderator variables. In particular, the moderating effect of knowledge on the relationship between corporate association and product-relevant perceived risk has not been tested in Korea. In the managerial implications of this research, we suggest the necessity to stress the ability that corporate manufactures the product well(CA association) than the accomplishment of corporate's social obligation(CSR association). This study suffers from various limitations that imply future research directions. The moderating effects of product category knowledge and involvement on the relationship between corporate association and perceived risk need to be replicated. Next, future research could explore whether the mediated effects of the perceived risk has the relationship between corporate association and consumer's product purchase. In addition, to ensure the external validity of the study will be needed to use realistic company, not artificial.

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The Moderating Role of Young Children's Playfulness and the Association between Maternal Parenting and Young Children's Peer Competency (어머니의 양육행동 및 유아의 놀이성과 유아의 또래 유능성 : 유아 놀이성의 조절효과를 중심으로)

  • Lee, Sang-Eun;Lee, Ju-Lie
    • Korean Journal of Child Studies
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    • v.31 no.6
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    • pp.71-85
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    • 2010
  • This study examined the moderating role of young children's playfulness and the association between maternal parenting and young children's peer competency. The subjects of the present study were 132 4 or 5-year-old young children and their mothers recruited from child-care centers in Seoul and Gyeonggi-Do. The findings of this Study were as follows : First, maternal parenting influenced children's peer competency. Second, young children's playfulness influenced young children's peer competency. Third, the association between overprotective and permissive maternal parenting styles and young children's leadership abilities were negative only in the low cognitive playfulness group. Fourth, the association between maternal rejective and negligent parenting and young children's socialibility were found to be negative only in the low physical playfulness group.

Leisure Study in Human Ecology : An Analytic Review (생활과학에서의 여가연구에 대한 분석적 고찰)

  • 김유경;기은광;이기영
    • Journal of Family Resource Management and Policy Review
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    • v.6 no.1
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    • pp.17-33
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    • 2002
  • The purpose of this study is to analyze leisure studies in human ecology of Korea and to discuss them. For this analysis, the articles which were published on the Journal of Korean Home Economics Association, the Journal of Korean Home Management Association, and the Journal of Korean Family Resource Management Association were investigated by theme, research subject, and research method. Leisure studies in human ecology began with the survey of time-use or activity patterns and they were focused on the housewives. Since the latter half of the 1990' s varied groups -especially the old- are subject to sample, and the shared leisure is studied, varied themes are studied. The research method were deflected to the survey using questionnaire all throughout the period. For the future study, we suggest that the general theories developed and the appropriate research method applied.

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Content Analysis of the Treatises Published in Journal of the Korean Home Economics Association (대한가정학회지 논문 내용 분석 연구: 1995-2009)

  • Cho, You-Hyun;Shin, Hee-Yong
    • Journal of the Korean Home Economics Association
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    • v.47 no.10
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    • pp.87-95
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    • 2009
  • This study conducted a content analysis of the treatises published in JKHEA(Journal of the Korean Home Economics Association). In total, 2,136 articles published in JKHEA from 1995 to the first half of 2009 were reviewed. Articles were classified by subject matters, research methods, number of researchers, presence of research fund, language and number of reference. Although it is useful to employ content analysis in reviewing academic articles on human ecology in all journal publications, the sheer size of literature available makes this task nearly impossible. As such, we have chosen JKHEA as a popular representative journal on human ecology. This study presented the empirical results of research trends and other characteristics in JKHEA. As such, the results of this study presented a snapshot analysis of research on human ecology and future trends.

Association between Environmental Perception and Subjective Health Status of Older Adults (노인의 환경인식과 주관적 건강과의 관련성)

  • Lee, Sungeun
    • Journal of Environmental Health Sciences
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    • v.44 no.4
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    • pp.391-396
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    • 2018
  • Objectives: The purpose of this study is to examine the level of community environmental perception of older adults and to identify the association between environmental perception and subjective health status among older persons. Methods: Analyses are based on data from Statistics Korea 2016 Social Survey. This study analyzed a total of 8,193 older adults aged 65 and over, and examined the association between environmental perception on air, water, soil, noise and vibration, and subjective health status using multiple regression analysis. Results: Study findings shown that environmental perception on water and soil had significant association with subjective health status of older adults. Specifically, older adults reported worse health status when they had more negative perceptions of water and soil environments in their communities. Conclusions: Results of this study suggested that efforts to enhance safety of drinking water and soil environments, and continuous research to identify relationship between environment and elderly health shoud be needed.

A Study of the Cultural Convergence Phenomenon in Contemporary Fashion (현대 패션에서 보여지는 컨버전스 문화 현상에 관한 연구)

  • Kim, Mi-Hyun
    • Journal of the Korean Home Economics Association
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    • v.46 no.4
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    • pp.61-69
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    • 2008
  • The definition of convergence employed in this study is a sociocultural phenomenon where different patterns, genres or fields coexist along with the existence of a knowledge based society. The focus of this study was centered on identifying the characteristics of contemporary fashion paradigm in association with changing cultural convergence according to the theories of Mark Weiser and other futurologists. The purpose of this study was to delve into the features of this paradigm in conjunction with changing cultural convergence in 21st century's knowledge-based society, and the influence of convergence paradigm on fashion. After identifying the features of knowledge-based society paradigm in association with changing cultural convergence, the characteristics of the fashion paradigm in order to ascertain and analyze fashion trends. Conclusions based on analyzed data indicate that in a knowledge-based society, paradigm change resulting from convergence phenomena contributes to facilitating the dissolution of fashion from other fields and its fusion with other areas.

Research Trend of Home Economics Education since 7th Curriculum (7차 교육과정 이후 가정과 교과교육의 연구 동향)

  • 양정혜;신상옥
    • Journal of the Korean Home Economics Association
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    • v.41 no.11
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    • pp.61-72
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    • 2003
  • The purpose of this study is try to suggest the practical trend of Home Economics Education by analyzing the trends of subject matter education in it. To do this, this study analyzed 115 articles published on The Journal of Korea Home Economics Education Association and The Journal of Korean Home Economics Association. Through this analyzing them, it is found out that teaching-teaming method and teaching materials are trend to be mainly concerned. But recently evaluation study and teacher education study in Home Economics Education have been increased. As a result, Home Economics Education needs to develop the speciality of Home Economics Education as a subject matter education.