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Genome-Wide Association Study of Hepatitis in Korean Populations

  • Hong, Youngbok (Department of Nanobiomedical Science, Dankook University) ;
  • Oh, Sejong (Department of Nanobiomedical Science, Dankook University)
  • Received : 2014.07.08
  • Accepted : 2014.09.24
  • Published : 2014.12.31

Abstract

Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong and Ansan cohort data. About 300,000 single-nucleotide polymorphisms and 20 epidemiological variables were analyzed. We did not find any meaningful significant single nucleotide polymorphisms, but we confirmed the influence of major epidemiological variables on hepatitis.

Keywords

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