• Proceedings of the KIEE Conference
• /
• 2003.07d
• /
• pp.2450-2452
• /
• 2003

We present a method to increase the productivity of multihead-gantry chip mounters for PCB assembly lines. To minimize the assembly time, we generate the mount sequence using the genetic algorithm. The chromosome, fitness function, and operators are newly defined to apply the algorithm. Simulation results are presented to verified the usefulness of the method.

• BMB Reports
• /
• v.45 no.8
• /
• pp.427-432
• /
• 2012

Primary cilia, single hair-like appendage on the surface of the most mammalian cells, were once considered to be vestigial cellular organelles for a past century because of their tiny structure and unknown function. Although they lack ancestral motility function of cilia or flagella, they share common ground with multiciliated motile cilia and flagella on internal structure such as microtubule based nine outer doublets nucleated from the base of mother centrioles called basal body. Making cilia, ciliogenesis, in cells depends on the cell cycle stage due to reuse of centrioles for cell division forming mitotic spindle pole (M phase) and assembling cilia from basal body (starting G1 phase and maintaining most of interphase). Ciliary assembly required two conflicting processes such as assembly and disassembly and balance between these two processes determines the length of cilia. Both process required highly conserved transport system to supply needed substance to grow tip of cilia and bring ciliary turnover product back to the base of cilia using motor protein, kinesin and dynein, and transport protein complex, IFT particles. Disruption of ciliary structure or function causes multiple human disorder called ciliopathies affecting disease of diverse ciliated tissues ranging from eye, kidney, respiratory tract and brain. Recent explosion of research on the primary cilia and their involvement on animal development and disease attracts scientific interest on how extensively the function of cilia related to specific cell physiology and signaling pathway. In this review, I introduce general features of primary cilia and recent progress in understanding of the ciliary length control and signaling pathways transduced through primary cilia in vertebrates.

• The Korean Journal of Zoology
• /
• v.38 no.2
• /
• pp.167-176
• /
• 1995

Glucose-regulated proteins (grp's), srp94 3nd grp78/BiP, are a group of stress proteins which are highly synthesized in cells exposed to a variety of stressful agents including tunicamycin 3nd Ca2+ ionophore. Grp78/BiP is hon to function as a molecular chaperone which regulates the folding and assembly of secretory or membrane proteins, but the biological function of grp941 remains to be elucidated. In this study, we have examined the intracellular distribution of grV's and the function of srp94. Grp's are resident in the endoplasmic reticulum (ERI 3nd a specific sequence (Lys-Asp-Glu-Leu) at their C-terminus is known to be responsible for their retention within the ER. However, it has been unclear whether upon disturbance of cellular Caa+ homeostasis by the Ca2+ ionophore, grp94 is retained within the ER or secreted into the medium. In this study, we showed that in the presence of C3a+ ionophore, grp94 and gif78/BiP are present in the cells, mainly within the ER. We have also investigated whether grp94 might function as a molecular chaperone. Here we showed that in the immunoglobulin (Ig)-secreting hvbridom3 cells, grp94 transientlY interacts with fully glycosylated Is heavy chain, suggesting that grpg94 may be involved in facilitating the folding and assembly of Ig heavy chains.

• The Bulletin of The Korean Astronomical Society
• /
• v.40 no.1
• /
• pp.46.3-46.3
• /
• 2015

As theoretical and empirical studies have pointed out, galaxy mergers play a pivotal role in galaxy mass assembly histories. Its contribution is considered to be more significant in more massive galaxies. In order to quantitatively understand the origin of stellar components in galaxies, we investigated stellar mass assembly histories as a function of galaxy and halo mass using semi-analytic approaches. In this study, we found that the most massive galaxies (log $M/M_{\odot}$ ~ 11.75 at z = 0), which are mostly the brightest cluster galaxies, obtain roughly 70% of their stellar components via mergers. The role of mergers monotonically declines with galaxy mass: less than 20% for log $M/M_{\odot}$ = 10.75 at z = 0. The contribution of galaxy mergers to stellar mass growth decays more slowly than that of in-situ star formation. Therefore, merger accretion becomes a dominant channel for stellar mass growth of the most massive group since z~2. However, when it comes to central galaxies in haloes less massive than $10^{13}_{\odot}$, star formation is always dominant.

• Proceedings of the KSME Conference
• /
• 2001.06c
• /
• pp.116-121
• /
• 2001

Verification of tool collision is an important issue in die and mold machining. In this paper three functions of verification are schematically explained based on Z-Map model. The first function is getting a collision-free region when a tool assembly and a part surface model are given. The second function estimates the shortest length of cutter shank with that the tool cuts all of a region without collision. The last one is cutting simulation considering all parts of tool assembly as well as cutter blade. Those functions can be easily implemented by using several basic operators of Z-Map model which are explained also. Proposed approaches have enough accuracy to verify collision in reasonable computing time.

• Journal of the Korean Society for Precision Engineering
• /
• v.19 no.6
• /
• pp.35-42
• /
• 2002

Verification of tool collision Is an important issue in die and mold machining. In this paper three functions of verification for 3-axis milling machining are schematically explained. Operators of geometric models are explained at first, which will be used in the functions of verification. The first verification function is getting a collision-free region when a tool assembly and a part surface model are given. The second function estimates the shortest length of cutter shank with that the tool cuts all of a region without collision The last one is cutting simulation considering all parts of tool assembly as well as cutter blade. Proposed approaches can be easily implemented by using several basic operators of geometric model. An example to calculate collision-free region is presented also.

• Journal of People, Plants, and Environment
• /
• v.24 no.3
• /
• pp.277-283
• /
• 2021

Background and objective: This study was conducted to increase understanding of agriculture through agricultural experience programs for adolescents living in self-reliance residence hall, and to investigate changes in work performance ability through changes in hand function. Methods: There were 11 subjects, and the average age was 18.2 years, all males without disabilities. The agricultural experience program consists of a total of 10 sessions including orientation and watching videos on future agriculture, creating vegetable gardens, planting, managing each crop, harvesting, visiting the processing room, and selling at a local food store. Results: The change in agricultural literacy by the agricultural experience program positively improved from a score of 113.73 to 127.91 (p = .008). The changes by sub-item are as follows. The value and safety of agri-foods (p = .020) and agriculture and natural environment (p = .007) were significantly improved. The function and value of rural areas (p = .050), production of agricultural products (p = .160), processing and distribution of agricultural products (p = .248), and agricultural policies (p = .058) were not significantly changed. The simple function of the hands was measured by the number of pegs inserted during 30 seconds, and the assembly function was measured by the number of pegs inserted during 60 seconds. In the case of simple function, the dominant hand was improved from 14.82 to 15.83 (p = .014), andthe non-dominant hand was also significantly improved from 13.79 to 15.01 (p = .002). There was no significant improvement in the simple function (p = .153) and assembly function (p = .770) of both hands. Conclusion: It is considered that the agricultural experience program will enable youths living in self-reliance residence halls to enhance their understanding of agriculture as an occupation, and enable them to play a role as wise consumers by positively affecting improvements in their agricultural literacy and simple hand functions.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.587-591
• /
• 2003

This study develops a neural network for solving optimization problems. Hopfield network has been used for such problems, but it frequently gives abnormal solutions or non-optimal solutions. Moreover, it takes much time for solving a solution. To overcome such disadvantages, this study adopts a neural network whose output nodes change with a small value at every evolution, and the proposed neural network is applied to solve ALB (Assembly Line Balancing) problems . Given a precedence diagram and a required number of workstations, an ALB problem is solved while achieving even distribution of workload among workstations. Here, the workload variance is used as the index of workload deviation, and is reflected to an energy function. The simulation results show that the proposed neural network yields good results for solving ALB problems with high success rate and fast execution time.

• IE interfaces
• /
• v.12 no.4
• /
• pp.617-624
• /
• 1999

In order to maximize an availability of machine and utilization of space, the parallel machines scheduling problem with space limit is frequently discussed in the industrial field. In this paper, we consider a scheduling problem for assembly machine in ship engine assembly shop. This paper considers the parallel machine scheduling problem in which n jobs having different release times, due dates and space limits are to be scheduled on m parallel machines. The objective function is to minimize the sum of earliness and tardiness. To solve this problem, a heuristic is developed. The proposed heuristic is divided into three modules hierarchically: job selection, machine selection and job sequencing, solution improvement. To illustrate its effectiveness, a proposed heuristic is evaluated with a large number of randomly generated test problems based on the field situation. Through the computational experiment, we determine the job selection rule that is suitable to the problem situation considered in this paper and show the effectiveness of our heuristic.

• Journal of Korean Institute of Industrial Engineers
• /
• v.23 no.3
• /
• pp.515-532
• /
• 1997

When balancing mixed model assembly lines (MMALs), workload smoothness should be considered on the model-by-model basis as well as on the station-by-station basis. This is because although station-by-station assignments may provide the equality of workload to workers, it causes the utilization of assembly lines to be inefficient due to the model sequences. This paper presents a genetic algorithm to improve the workload smoothness on both the station-by-station and the model-by-model basis in balancing MMALs. Proposed is a function by which the two kinds of workloads smoothness can be evaluated according to the various preferences of line managers. To enhance the capability of searching good solutions, our genetic algorithm puts emphasis on the utilization of problem-specific information and heuristics in the design of representation scheme and genetic operators. Experimental results show that our algorithm can provide better solutions than existing heuristics. In particular, our algorithm is outstanding on the problems with a larger number of stations or a larger number of tasks.