• Title/Summary/Keyword: Article Combination

Search Result 252, Processing Time 0.027 seconds

Proteomics approaches for the studies of bone metabolism

  • Lee, Ji-Hyun;Cho, Je-Yoel
    • BMB Reports
    • /
    • v.47 no.3
    • /
    • pp.141-148
    • /
    • 2014
  • Bone is an active tissue, in which bone formation by osteoblast is followed by bone resorption by osteoclasts, in a repeating cycle. Proteomics approaches may allow the detection of changes in cell signal transduction, and the regulatory mechanism of cell differentiation. LC-MS/MS-based quantitative methods can be used with labeling strategies, such as SILAC, iTRAQ, TMT and enzymatic labeling. When used in combination with specific protein enrichment strategies, quantitative proteomics methods can identify various signaling molecules and modulators, and their interacting proteins in bone metabolism, to elucidate biological functions for the newly identified proteins in the cellular context. In this article, we will briefly review recent major advances in the application of proteomics for bone biology, especially from the aspect of cellular signaling.

On the use of numerical models for validation of high frequency based damage detection methodologies

  • Aguirre, Diego A.;Montejo, Luis A.
    • Structural Monitoring and Maintenance
    • /
    • v.2 no.4
    • /
    • pp.383-397
    • /
    • 2015
  • This article identifies and addresses current limitations on the use of numerical models for validation and/or calibration of damage detection methodologies that are based on the analysis of the high frequency response of the structure to identify the occurrence of abrupt anomalies. Distributed-plasticity non-linear fiber-based models in combination with experimental data from a full-scale reinforced concrete column test are used to point out current modeling techniques limitations. It was found that the numerical model was capable of reproducing the global and local response of the structure at a wide range of inelastic demands, including the occurrences of rebar ruptures. However, when abrupt sudden damage occurs, like rebar fracture, a high frequency pulse is detected in the accelerations recorded in the structure that the numerical model is incapable of reproducing. Since the occurrence of such pulse is fundamental on the detection of damage, it is proposed to add this effect to the simulated response before it is used for validation purposes.

Sinonasal sarcoidosis of the maxillary sinus and infraorbital nerve: a case report

  • Joseph, Benny;Vyloppilli, Suresh;Sayd, Shermil;Ummer, Niyas
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.41 no.4
    • /
    • pp.217-221
    • /
    • 2015
  • Sinonasal sarcoidosis in the head and neck region is infrequent. Its occurrence can be either isolated in combination with other systems. The literature reveals that the occurrence of sinonasal sarcoidosis without lung involvement is rare. In general, sarcoidosis is a chronic non-caseating granulomatous disease of unknown origin, often identified after biopsy. In this article, we report on a benign tumor of the face that produced a diagnostic dilemma, necessitating refinement of the surgical access and in toto removal of the benign tumor.

Composite Ni-TiO2 nanotube arrays electrode for photo-assisted electrolysis

  • Pozio, Alfonso;Masci, Amedeo;Pasquali, Mauro
    • Advances in Energy Research
    • /
    • v.3 no.1
    • /
    • pp.45-57
    • /
    • 2015
  • This article is addressed to define a new composite electrode constituted by porous nickel and an array of highly ordered $TiO_2$ nanotubes obtained by a previous galvanostatic anodization treatment in an ethylene glycol solution. The electrochemical performances of the composite anode were evaluated in a photo-electrolyser, which showed good solar conversion efficiency with respect to the UV irradiance together with a reduction of energy consumption. Such a combination of materials makes our system simple and able to work both in dark and under solar light exposure, thus opening new perspectives for industrial-scale applications.

Recent Progress in Cathode Materials for Thermal Batteries

  • Ko, Jaehwan;Kang, Seung Ho;Cheong, Hae-Won;Yoon, Young Soo
    • Journal of the Korean Ceramic Society
    • /
    • v.56 no.3
    • /
    • pp.233-255
    • /
    • 2019
  • Thermal batteries are reserve batteries with molten salts as an electrolyte, which activates at high temperature. Due to their excellent reliability, long shelf life, and mechanical robustness, thermal batteries are used in military applications. A high-performance cathode for thermal batteries should be considered in terms of its high capacity, high voltage, and high thermal stability. Research progress on cathode materials from the recent decade is reviewed in this article. The major directions of research were surface modification, compounding of existing materials, fabrication of thin film cathode, and development of new materials. In order to develop a high-performance cathode, a proper combination of these research directions is required while considering mass production and cost.

Development of Methods to lmprove the Reliability of ELECTRE (복합기준 평가방법 ELECTRE의 신뢰도 증진을 위한 방안 연구)

  • 이인성
    • Journal of the Korean Institute of Landscape Architecture
    • /
    • v.23 no.1
    • /
    • pp.23-38
    • /
    • 1995
  • ELEECTRE is a less demanding and potentially Bffective multiattribute evaluation method for pre-editing proeedure. The method, however, was developed based on probabilistic mathematicsand its reliability has never'been emprieally tested. This article examined the reliability of ELECTRo under various conditions of linear and non-linear utility func- tions using a Monte-Carlo shnulation, and found the method eausea a considerably high rate of error. To enhance the reliability of ELECTRE, two ways of modi(ication - adjust- ment of threshold values of concordance and discordance matrices, and adjustment of the required nunlber of probably-dominant alternatives to eliminate a probably-dominated alternative - were suggested, and their effctiveness was also tesed by a Monte-Carlo simulation. The simulation result chows that these modifications cponsiderably improve the reliability of ELECTRE, and yet maintain a reasonably high level of efficiency. Through these modifications, ELECTRE can be used as an efficient and feliable pre-editing method. Ways to implement ELECTRE in the construction of plainning decision support systens were discussed. The impli(els combination of this method and other multiattribute evaluation methods will help to create more effective decision suport systems.

  • PDF

A Study on the Cost-Effect Analysis between Portal-Based and SNS-Based Advertisements (e러닝에서 소셜커머스 기반의 광고와 포털사이트 기반의 광고 간 투자비용 대비 효과에 관한 비교 연구)

  • Kim, Chang Su;Kwon, Woo Seuk;Lee, Sung Ho
    • Journal of Korea Society of Digital Industry and Information Management
    • /
    • v.9 no.4
    • /
    • pp.213-226
    • /
    • 2013
  • Recently, the social commerce on Facebook.com and Twitter.com, which is represented by SNS (Social Network Service), has been expanding in the form of a combination of SNS market. This study attempted to examine the cost-effect analysis between portal-based advertisement and SNS-based advertisement in order to establish an effective advertising strategy for e-learning content providers. The results showed that portal-based advertisement is more effective than SNS-based advertisement in terms of advertising effectiveness against cost. According to these empirical research results, this article discusses the practical implications for e-learning content providers in an attempt to enable them to take competitive advantage.

Frequency response analysis of curved embedded magneto-electro-viscoelastic functionally graded nanobeams

  • Ebrahimi, Farzad;Fardshad, Ramin Ebrahimi;Mahesh, Vinyas
    • Advances in nano research
    • /
    • v.7 no.6
    • /
    • pp.391-403
    • /
    • 2019
  • In this article the frequency response analysis of curved magneto-electro-viscoelastic functionally graded (CMEV-FG) nanobeams resting on viscoelastic foundation has been carried out. To this end, the study incorporates the Euler-Bernoulli beam model in association with Eringen's nonlocal theory to incorporate the size effects. The viscoelastic foundation in the current investigation is assumed to be the combination of Winkler-Pasternak layer and viscous layer of infinite parallel dashpots. The equations of motion are derived with the aid of Hamilton's principle and the solution to vibration problem of CMEV-FG nanobeams are obtained analytically. The material gradation is considered to follow Power-law rule. This study thoroughly investigates the influence of prominent parameters such as linear, shear and viscous layers of foundation, structural damping coefficient, opening angle, magneto-electrical field, nonlocal parameter, power-law exponent and slenderness ratio on the frequencies of FG nanobeams.

Structural Analysis Simulation of Cantilever Shaped Piezoelectric Energy Harvester Using COMSOL Multiphysics (COMSOL Multiphysics를 활용한 캔틸레버 형태의 압전 에너지 하베스터 구조 해석 시뮬레이션)

  • Kwak, Min Sub;Hwang, Geon-Tae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.34 no.6
    • /
    • pp.416-425
    • /
    • 2021
  • In the 4th industrial age, electronic devices are becoming smaller and lighter with a low power consumption to overcome spatial limitation. The piezoelectric energy harvesters can convert mechanical kinetic energy into electric energy; thus, enabling the operation of small electronic devices. Recently, various piezoelectric harvesters have been reported and the electric output from these harvesters could be anticipated by theoretical analysis methods. For example, COMSOL Multiphysics software provides a theoretical simulation of piezoelectric effect with a combination of mechanical and electrical phenomena in the piezoelectric materials. This article introduces a brief modeling of piezoelectric harvester to investigate mechanical stress and electrical output of harvesting devices by the COMSOL Multiphysics software.

Research Trends and Prospects on the Measurement of Spray Development (분무발달 측정법에 대한 연구경향 및 전망)

  • Bang, Seung Hwan
    • Journal of ILASS-Korea
    • /
    • v.24 no.2
    • /
    • pp.89-96
    • /
    • 2019
  • This article gives an overview of spray measurement technique were reviewed and suggestions. Spray formation mechanism is the most intellectually challenging and practically important topics in fluid mechanics. Methods for analysis of existing spray development have been developed in various ways, but if there is no support for relatively sufficient equipment, there are limitations to analysis. The newly measured and analyzed method may exceed the threshold for preparation of analysis and, as the results of two-dimensional individual analysis are aggregated and analyzed in three dimensions by a combination of analysis methods, the method is considered a relatively accurate analysis method that analysis.