• 대한본초학회지
• /
• 제26권1호
• /
• pp.97-101
• /
• 2011

Objectives : The purpose of this research is to identify the actual origin species imported as Aquilaria malaccensis from Indonesia. Methods : After producing the permanent preparat by cutting off the specimen thinly, we observed its characteristics. Results : The imported ones have not interxylary parenchyma, so none is in the genus aquilaria. Since the aliform parenchyma is mostly observed around the vessel pore, they are in the genus gonystylus, and the rest have no aliform parenchyma, so their specimen is unidentified. Conclusion : The imported as A. malaccensis are not in the genus aquilaria, but most of them are in the genus gonystylus and, for the rest, the specimen is unidentified.

• 대한본초학회지
• /
• 제28권5호
• /
• pp.13-19
• /
• 2013

Objectives : The purpose of this study is correct the scientific name of Aquilariae Lignum in Korean Herbal Pharmacoepia. Methods : The production areas of Aquilariae Lignum and its trading status with China in Chinese history, Sanscrit-Chinese Translation Sutra, Naming year and the discovered district in main Aquilaria spp., Several nation's Pharmacoepia, The Plant List(TPL), Convention on International Trade in Endangered Species of Wild fauna and flora(CITES) and The International Union for Conservation of Nature(IUCN) were cross-checked. Results : The records in the Jiaozhouyiwuzhi written in the early 2nd century said that Aquilariae Lignum was produced in Vietnam. NanfangCaomuZhuang written in 304 said that Agarwood in Vietnam had white flowers. Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty. Aquilariae Lignum from Malaysia and Indonesia was not traded with China. In Sanscrit-Chinese Translation Sutra, India Aquilariae Lignum was translated as Vietnam Aquilariae Lignum. Aquilaria malaccensis was discovered from Malay-Peninsular in 1783, and has green or dirty yellow flowers. A. agallocha from North-Eastern India in 1814, white flowers. A. crasssna from Vietnam in 1914, white flowers. A. crassna is different from A. malaccensis in several ways, such as flower, fruit, seed and disribution. In several Nation's Pharmacoepia, A. crassna was a synonym of A. agallocha. But in TPL, CITES and IUCN, A. malaccensis was an accepted name, and A. agallocha was a synonym of A. malaccensis. Conclusions : These results show that the original species of Aquilariae Lignum in Korea Herbal Pharmacoepia should be reversed from A. agallocha to A. crassna Pierre ex Lacomte.

• Natural Product Sciences
• /
• 제25권2호
• /
• pp.157-164
• /
• 2019

The study was conducted to investigate the acute and sub-acute toxicity effect of Aquilaria malaccensis leaves aqueous extract (AEAM) towards male ICR mice in terms of body weight, relative organ weight, mortality rate and sperm parameters. In acute toxicity study, a single dose at of 2000 mg/kg was performed. In sub-acute toxicity study, the mice were received normal saline (control group), 50, 100, 150, 200, 500, or 1000 mg/kg of AEAM orally for 21 days of treatment. In sub-acute toxicity study, the number of abnormal sperm were significantly decreased in AEAM 100, 150, 200, 500, and 1000 when compared to the control group. While, the motility of sperm were found to be significantly increased in AEAM 100, 150, 200, and 1000 as compared to the control group. No mortality was recorded in the control group and treated groups in both toxicity studies except for one mouse from AEAM 1000 group. However, the mild sedative effect in terms of the tendency to sleep was clearly noticeable in both toxicity studies. Results indicated that the AEAM can be one of the useful alternative medicine to enhance fertility rate by increasing healthy sperm production.

• 대한본초학회지
• /
• 제20권3호
• /
• pp.9-18
• /
• 2005

Objectives : The purpose of this study is to investigate characteristics of cell morphology of two different agar woods (Aquilaria agallocha Roxburgh (AAR) and imitative agar wood (IAW)) using microscopic techniques. Methods : Both light and scanning electron microscopes were used to observe morphological and histological features of the cell of agar woods collected from commercial products in the market. Results : The cell morphology and tissue arrangements of AAR depending on either the adsorption of resin into vessels or no adsorption of resin were observed to compare these features with those of both IAW and Aquilaria sinensis Gilb (ASG). Conclusions : As a result, the vessels of AAR with the resin adsorption was packed with lots of yellow-brownish materials, which were quite different from those of IAW and ASG. The cell walls were thick, and had well-developed traumatic parenchyma tissues with squared cells of the same height and width, which appeared as a clump of small grains packed.

• 대한본초학회지
• /
• 제26권4호
• /
• pp.163-168
• /
• 2011

Objective : The purpose of this study is to determine the origin of Aquilariae Lignum. Method : Firstly identify the production areas of Aquilariae Lignum and its trading status with China in Chinese history through Chinese historical books such as Twenty-Five Histories(二十五史) and the records of the Chosun Dynasty and then, compare the distribution of the genus Aquilaria in the concerned areas. Result : Since the records in the NanfangCaomuZhuang(南方草木狀) written in 304 saying that Aquilariae Lignum was produced in Vietnam and had white flowers, Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty(淸代). Even though Thailand traded Aquilariae Lignum during Qing Dynasty, however, the volume was at a low level. Aquilariae Lignum from southern Thailand, Malaysia and Indonesia was rated as low quality and low-priced because of its fishy smell and strong flavor. Conclusion : These results show that the origin of Aquilariae Lignum comes from Vietnam and this species is distinguished from the ones of Indodesia or Malaysia.

• Journal of the Korean Wood Science and Technology
• /
• 제47권4호
• /
• pp.459-471
• /
• 2019

Several species of Aquilaria and Gyrinops are native to Indonesia and well known as agarwood-producing trees with a high economic value. Their bioactive compounds have a wide spectrum of uses, such as in medicine and cosmetics. These genera have undergone extensive search for novel bioactive compounds. The purpose of this study was to isolate, identify, and characterize the endophytic fungi community associated with Aquilaria malaccensis, A. microcarpa, Gyrinops versteegii, and A. crassna trees and investigate their bioactive properties as antioxidant agents and antagonists. A total of 50 fungi were successfully isolated from different tissues of the four species of agarwood-producing trees. Two isolates exhibited strong antioxidant activity, namely, Apodus oryzae (R2MC3A, $IC_{50}$ 60.92 mg/mL) and Diaporthe sp. (P1DS1[C], $IC_{50}$ 76.65 mg/mL). Two isolates, Pestalotiopsis theae (P3BS3[B]) and Curvularia sp. (P2CD3A), showed >75% antifungal activity against pathogenic Fusarium solani. The results revealed that endophytic fungi associated with the studied agarwood-producing trees had potential antioxidant and antifungal activities for further applications in biotechnology.

• 대한본초학회지
• /
• 제26권1호
• /
• pp.7-12
• /
• 2011

Objectives : The purpose of this study is to evaluate the quality of four different kinds of agarwood and analysis chemical constituents by GC-MS. Methods : Four source plants were two of Vietnamese agarwood, Indonesian agarwood and Myanmar agarwood. These plant materials were named sample No. 1-4. The chemical constituents of each agarwood were analysed by GC-MS. Results : GC-MS analysis showed that ${\beta}$-selinene was found in all the samples. The Vietnamese agarwood, Sample 1, and 4 has contained 6.861% and 7.497% of ${\beta}$-selinene and reached the highest level at the retention times 46.245 and 46.274 (min). Sample 2, the Myanmar agarwood has contained 1.608%, the lowest level of ${\beta}$-selinene, and it also has contained about 20% of ${\alpha}-,{\beta}-,{\gamma}$-eudesmol and 4.076% of valerianol. Sample 3, the Indonesian agarwood has contained 9.59% of ${\beta}$-selinene, 9.493% of ${\beta}$-selinene and shown its highest level (more than 19%) at the retention time 43.998 (min). Conclusion : It suggested that ${\beta}$-selinene could be a standard marker to evaluate agarwood by GC-MS analysis.

• 생명과학회지
• /
• 제31권8호
• /
• pp.745-754
• /
• 2021

면역 기능의 저하는 각종 감염에 대한 저항력의 부족을 초래하여 다양한 질병 유발에 기여하며, 면역 억제제의 부작용을 감소시키거나 면역력을 높이기 위해 면역 조절 생체 물질이 사용되고 있다. 침향은 침향나무의 방향족수지 부분이며 전통적으로 다양한 질병을 치료하기 위한 목적으로 사용되어왔다. 비록 선행 연구들에 의하여 침향이 신체의 면역력을 향상시킬 수 있다는 사실이 밝혀졌지만 이에 대한 근거는 여전히 부족한 실정이다. 본 연구에서는 인도네시아에서 구입한 A. malaccensisd 침향 메탄올 추출물의 면역 자극 효과를 RAW 264.7 대식세포 모델에서 평가하였다. 본 연구의 결과에 의하면 침향 추출물은 세포 독성이 없는 조건에서 식작용을 현저하게 향상시켰으며다. 또한 침향 추출물 처리된 RAW 264.7 세포는 활성화된 대식세포의 전형적인 형태를 보였으며, iNOS 발현 증가에 따른 NO 생성의 생성을 크게 증가시켰다. 아울러 TNF-α, IL-1β 및 IL-6과 같은 cytokine의 발현과 분비를 증가시켰으며, MAPKs 신호 전달 경로를 활성화시켰다. 따라서 본 연구의 결과는 고대 서적을 기반으로 침향의 효과를 확인하는 데 중요한 의미가 있으며, 침향이 잠재적인 면역 강화 효과가 있다는 근거를 제시하는 것이다.