• Title/Summary/Keyword: Application protocol

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Factors Affecting Hemolysis in Blood Sampling and Repeated Sampling in the Emergency Department (응급실에서의 채혈로 인한 용혈 및 재채혈 관련요인)

  • Cho, Myung Sook;Hwang, Moon Sook
    • Journal of Korean Clinical Nursing Research
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    • v.17 no.3
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    • pp.399-410
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    • 2011
  • Purpose: This study was conducted to investigate the incidence of blood hemolysis and repeated blood sampling and to identify factors contributing to hemolysis and repeated blood sampling in the emergency department. Methods: A cross-sectional descriptive design was used. Participants were the patients who came to emergency department and are required a blood sampling for electrolyte level. All blood samples were collected by emergency department nurses and determined for hemolysis by experienced laboratory technologists. Data were analyzed using $x^2$-test, Fisher's exact test, Mann-Whitney u test and Binary Logistic Regression to determine significant differences. Results: A total of 402 valid samples were collected. Of these, 30 blood samples (7.5%) were found to be hemolyzed and 9 (2.2%) to be recollected. Statistically significant factors affecting on hemolysis and repeated blood sampling included the time of bloods sampling (night), the time of tourniquet application, and too-fast blood draw into the test tube. Conclusion: We recommend that nurses who take the blood sampling to consider the findings of the study and take the related factors into account as they set up the standardized care protocol in order for nursing quality improvement.

Fundamental characteristic analysis on 6 T-class high-temperature superconducting no-insulation magnet using turn-distributed equivalent circuit model

  • Liu, Q.;Choia, J.;Sim, K.;Kim, S.
    • Progress in Superconductivity and Cryogenics
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    • v.23 no.4
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    • pp.44-48
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    • 2021
  • In order to obtain ultra-high resolution MRI images, research and development of 11 T or higher superconducting magnets have been actively conducted in the world, recently. The high-temperature superconductor (HTS), first discovered in 1986, was very limited in industrial application until mid-2010, despite its high critical current characteristics in the high magnetic field compared to the low-temperature superconductor. This is because HTS magnets were unable to operate stably due to the thermal damage when a quench occurred. With the introduction of no-insulation (NI) HTS magnet winding technology that does not burn electrically, it could be expected that the HTS magnets are dramatically reduced in weight, volume, and cost. In this paper, a 6 T-class NI HTS magnet for basic characteristic analysis was designed, and a distributed equivalent circuit model of the NI coils was configured to analyze the charging current characteristics caused by excitation current, and the charge delay phenomenon and loss were predicted through the development of a simulation model. Additionally, the critical current of the NI HTS magnets was estimated, considering the magnetic field, its angle and temperature with a given current. The loss due to charging delay characteristics was analyzed and the result was shown. It is meaningful to obtain detailed operation technology to secure a stable operation protocol for a 6T NI HTS magnet which is actually manufactured.

Applying the IoT platform and green wave theory to control intelligent traffic lights system for urban areas in Vietnam

  • Phan, Cao Tho;Pham, Duy Duong;Tran, Hoang Vu;Tran, Trung Viet;Huu, Phat Nguyen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.34-52
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    • 2019
  • This paper proposes an intelligent system performing an application with assistance of an Internet of Things (IoT) platform to control a traffic lights system. In our proposed systems, the traffic lights can be remotely controlled through the Internet. Based on IoT platform, the traffic conditions at different intersections of roads are collected and the traffic lights are controlled in a central manner. For the software part, the algorithm is designed based on the green wave theory to maximize the green bandwidth of arterial roads while addressing a challenging issue: the rapid changes of parameters including cycle time, splits, offset, non-fixed vehicles' velocities and traffic flow along arterial roads. The issue typically happens at some areas where the transportation system is not well organized like in Vietnam. For the hardware part, PLC S7-1200 are placed at the intersections for two purposes: to control traffic lights and to collect the parameters and transmit to a host machine at the operation center. For the communication part, the TCP/IP protocol can be done using a Profinet port embedded in the PLC. Some graphical user interface captures are also presented to illustrate the operation of our proposed system.

Connection Management Scheme using Mobile Agent System

  • Lim, Hee-Kyoung;Bae, Sang-Hyun;Lee, Kwang-Ok
    • Journal of Integrative Natural Science
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    • v.11 no.4
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    • pp.192-196
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    • 2018
  • The mobile agent paradigm can be exploited in a variety of ways, ranging from low-level system administration tasks to middle ware to user-level applications. Mobile agents can be useful in building middle-ware services such as active mail systems, distributed collaboration systems, etc. An active mail message is a program that interacts with its recipient using a multimedia interface, and adapts the interaction session based on the recipient's responses. The mobile agent paradigm is well suitable to this type of application, since it can carry a sender-defined session protocol along with the multimedia message. Mobile agent communication is possible via method invocation on virtual references. Agents can make synchronous, one-way, or future-reply type invocations. Multicasting is possible, since agents can be aggregated hierarchically into groups. A simple check-pointing facility has also been implemented. Another proposed solution is to use multi agent computer systems to access, filter, evaluate, and integrate this information. We will present the overall architectural framework, our agent design commitments, and agent architecture to enable the above characteristics. Besides, the each information needed a mobile agent system such as text, graphic, image, audio and video etc, constructed a great capacity multimedia database system. However, they have problems in establishing connections over multiple subnetworks, such as no end-to-end connections, transmission delay due to ATM address resolution, no QoS protocols. We propose a new connection management scheme in the thesis to improve the connection management involved of mobile agent systems.

Synthesis of 125I-labeled thiol-reactive prosthetic group for site-specific radiolabeling of human serum albumin

  • Shim, Ha Eun;Song, Lee;Jeon, Jongho
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.4 no.2
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    • pp.85-89
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    • 2018
  • We demonstrate a detail protocol for the radiosynthesis of an $^{125}I$-labeled MSTP prosthetic group and its application to the efficient radiolabeling of human serum albumin (HSA). Radioiodination of the precursor (2) was carried out by using $[^{125}I]$NaI and chloramine T as an oxidant at room temperature for 15 min. After HPLC purification of the crude product, the purified $^{125}I$-labeled MSTP ($[^{125}I]1$) was obtained with high radiochemical yield ($73{\pm}5%$, n = 3) and excellent radiochemical purity (>99%). Site-specific reaction between ($[^{125}I]1$) and HSA gave the $^{125}I$-labeled human serum albumin ($[^{125}I]3$) with more than 99% of radiochemical yield as determined by radio-thin-layer chromatography (radio-TLC). These results clearly demonstrate that the present radiolabeling method will be useful for the efficient and convenient radiolabeling of thiol-bearing biomolecules.

The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis

  • Zhu, Libing;Kim, Yunjin;Yang, Zongbao
    • Journal of Acupuncture & Meridian Studies
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    • v.11 no.6
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    • pp.343-354
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    • 2018
  • Auriculotherapy has been extensively used for chronic spontaneous urticaria in China. However, the evidence of its effectiveness and safety for the treatment of chronic spontaneous urticaria is insufficient. Hence, we conducted this study to compare auriculotherapy or auriculotherapy joint treatment with Western medicine for the cure of chronic spontaneous urticaria. This meta-analysis of seven randomized controlled trials showed that auriculotherapy or auriculotherapy joint treatment was significantly superior to Western medicine in curing clinical signs and symptoms of chronic spontaneous urticaria [odds ration (OR), 2.61; 95% confidence interval (CI), 1.54-4.43; p = 0.0004) and also better in total effect rate (OR, 3.81; 95% CI, 2.07-7.01; p<0.0001). But, auriculotherapy or auriculotherapy joint treatment was similar to Western medicine in improving clinical signs and symptoms of chronic spontaneous urticaria (OR, 0.74; 95% CI, 0.35-1.56; p = 0.42). Auriculotherapy or auriculotherapy joint treatment was safer than Western medicine for curing chronic spontaneous urticaria (OR, 0.26; 95% CI, 0.09-0.80; p = 0.02). Auriculotherapy alone or auriculotherapy joint treatment appears to be more effective and safer than Western medicine that contains antihistamines in the treatment of chronic spontaneous urticaria. However, these findings should be interpreted with caution due to the unclear risk bias of methodological quality, and further studies with large-scale, better, and more rigorously designed protocol are necessary to prove these findings.

Application of KORSLE to Estimate Soil Erosion at Field Scale (한국형 토양유실공식에 의한 토양유실량 현장예측)

  • Song, Jae Min;Yang, Jae E;Lim, Kyoung Jae;Park, Youn Shik
    • Journal of Soil and Groundwater Environment
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    • v.24 no.5
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    • pp.31-41
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    • 2019
  • In 2013, the Ministry of Environment in South Korea promulgated a new regulatory bulletin that contained revised enforcement ordinance on soil management protocols. The bulletin recommends the use of Universal Soil Loss Equation (USLE) for the soil erosion estimation, but USLE has limited applicability in prediction of soil erosion because it does not allow direct estimation of actual mass of soil erosion. Therefore, there is a great need of revising the protocol to allow direct comparison between the measured and estimated values of soil erosion. The Korean Soil Loss Equation (KORSLE) was developed recently and used to estimate soil loss in two fields as an alternative to existing USLE model. KORSLE was applied to estimate monthly rainfall erosivity indices as well as temporal variation in potential soil loss. The estimated potential soil loss by KORSLE was adjusted with correction factor for direct comparison with measured soil erosion. The result was reasonable since Nash-Stucliff efficiency were 0.8020 in calibration and 0.5089 in validation. The results suggest that KORSLE is an appropriate model as an alternative to USLE to predict soil erosion at field scale.

Conjugation of vascular endothelial growth factor to poly lactic-co-glycolic acid nanospheres enhances differentiation of embryonic stem cells to lymphatic endothelial cells

  • Yoo, Hyunjin;Choi, Dongyoon;Choi, Youngsok
    • Animal Bioscience
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    • v.34 no.4
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    • pp.533-538
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    • 2021
  • Objective: Pluripotent stem cell-derived lymphatic endothelial cells (LECs) show great promise in their therapeutic application in the field of regenerative medicine related to lymphatic vessels. We tested the approach of forced differentiation of mouse embryonal stem cells into LECs using biodegradable poly lactic-co-glycolic acid (PLGA) nanospheres in conjugation with growth factors (vascular endothelial growth factors [VEGF-A and VEGF-C]). Methods: We evaluated the practical use of heparin-conjugated PLGA nanoparticles (molecular weight ~15,000) in conjugation with VEGF-A/C, embryoid body (EB) formation, and LEC differentiation using immunofluorescence staining followed by quantification and quantitative real-time polymerase chain reaction analysis. Results: We showed that formation and differentiation of EB with VEGF-A/C-conjugated PLGA nanospheres, compared to direct supplementation of VEGF-A/C to the EB differentiation media, greatly improved yield of LYVE1(+) LECs. Our analyses revealed that the enhanced potential of LEC differentiation using VEGF-A/C-conjugated PLGA nanospheres was mediated by elevation of expression of the genes that are important for lymphatic vessel formation. Conclusion: Together, we not only established an improved protocol for LEC differentiation using PLGA nanospheres but also provided a platform technology for the mechanistic study of LEC development in mammals.

Software Library Design for GNSS/INS Integrated Navigation Based on Multi-Sensor Information of Android Smartphone

  • Kim, Youngki;Fang, Tae Hyun;Seo, Kiyeol
    • Journal of Positioning, Navigation, and Timing
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    • v.11 no.4
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    • pp.279-286
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    • 2022
  • In this paper, we designed a software library that produces integrated Global Navigation Satellite System (GNSS) / Inertial Navigation System (INS) navigation information using the raw measurements provided by the GNSS chipset, gyroscope, accelerometer and magnetometer embedded in android smartphone. Loosely coupled integration method was used to derive information of GNSS /INS integrated navigation. An application built in the designed library was developed and installed on the android smartphone. And we conducted field experiments. GNSS navigation messages were collected in the Radio Technical Commission for Maritime Service (RTCM 3.0) format by the Network Transport of RTCM via Internet Protocol (NTRIP). As a result of experiments, it was confirmed that design requirements were satisfied by deriving navigation such as three-dimensional position and speed, course over ground (COG), speed over ground (SOG), heading and protection level (PL) using the designed library. In addition, the results of this experiment are expected to be applicable to maritime navigation applications using smart device.

Method of Real-time Communication in Android OS (안드로이드 운영체제 상에서 실시간 통신 방법)

  • Woo, Sang-Ho;Lee, Sang-Gil;Lee, Cheol-Hoon
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.475-484
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    • 2021
  • The Android OS has quickly established itself with the smartphone market and is being applied in a variety of ways such as navigation and refrigerator panels. Existing terminals can implement services that require high precision while using RTOS that requires accurate execution time, but Android OS has a disadvantage in that it cannot provide high-precision real-time performance. In this paper, we propose a real-time communication method that operates in the Android OS. Real-time communication reduces the load using the UDP protocol, and configures the real-time operating system time tick through a high-precision timer in the kernel area. An Android application level library was created to implement real-time communication and compared with the existing Android library for real-time performance verification.