• Biomolecules & Therapeutics
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• v.22 no.3
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• pp.232-238
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• 2014

Alzheimer's disease (AD) is the most common neurodegenerative disease without known ways to cure. A key neuropathologic manifestation of the disease is extracellular deposition of beta-amyloid peptide (Ab). Specific mechanisms underlying the development of the disease have not yet been fully understood. In this study, we investigated effects of 4-O-methylhonokiol on memory dysfunction in APP/PS1 double transgenic mice. 4-O-methylhonokiol (1 mg/kg for 3 month) significantly reduced deficit in learning and memory of the transgenic mice, as determined by the Morris water maze test and step-through passive avoidance test. Our biochemical analysis suggested that 4-O-methylhonokiol ameliorated $A{\beta}$ accumulation in the cortex and hippocampus via reduction in beta-site APP-cleaving enzyme 1 expression. In addition, 4-O-methylhonokiol attenuated lipid peroxidation and elevated glutathione peroxidase activity in the double transgenic mice brains. Thus, suppressive effects of 4-O-methylhonokiol on $A{\beta}$ generation and oxidative stress in the brains of transgenic mice may be responsible for the enhancement in cognitive function. These results suggest that the natural compound has potential to intervene memory deficit and progressive neurodegeneration in AD patients.

• Journal of the Korean Society of Earth Science Education
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• v.9 no.1
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• pp.1-14
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• 2016

The purpose of this study is to develop SPA system using diagnostic and formative assessment in earth science classes in order to discuss its effect on learning achievement and self-directed learning attitude. For this purpose, we developed total management system, app for teachers, and app for students. This research was practiced to 76 students in 5th grade. The results are as follows. Firstly, the group taking a class used by app for diagnostic and formative assessment had an effect of improving learning achievement. However, as for learning achievement long term endurance test, the group taking a class using app for diagnostic and formative assessment had no effect. Secondly, the group taking a class using apps for diagnostic and formative assessment had an effect of improving learners' self-directed learning attitude. As for self-directed long-term endurance test, the group taking a class using app for diagnostic and formative assessment had an effect. In conclusion, I hope that this SPA system might apply to the science classes as it is a system that will satisfy the needs of both teachers and students, giving much needed feedback to students.

• International Journal of Contents
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• v.18 no.2
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• pp.32-46
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• 2022

In recent years, large-scale and high-density use of LED on facades has exposed some disadvantages, such as light pollution, high energy consumption, unsustainability, and poor interactivity. Because of the development of smartphones and augmented reality (AR), AR has emerged as a new technology available to users to interact with the media façade. As an augmented reality app for public space, the AR map app can superimpose virtual images on the surface of a building to form an AR media façade, which can be applied in the fields of navigation, advertising, interactive public art, smart retail, etc. This study establishes the variables influencing usage intention and the consequent outcomes of Huawei AR map app and uses the technology acceptance model (TAM) to discuss their relationship. Results show that consumer innovativeness, information quality, and design quality have a strong influence on perceived ease of use. Information quality has a positive impact on perceived usefulness, but design quality has a weak influence. Also, the design quality of Huawei AR map app and consumer innovativeness have a higher effect on perceived enjoyment than information quality. Users' usage attitude and perceived usefulness when using Huawei AR map app are key factors determining their usage intention. This study inspires city planners, architects, developers, and designers of AR apps that augmented reality can partly replace media façade, and that investment in augmented reality will achieve significant sustainable economic and social benefits.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.213-214
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• 2023

스마트폰은 앱을 통하여 사람들에게 다양하고 유용한 기능을 제공하며, 새로운 앱들이 계속해서 개발되어 출시되고 있다. 그러나 이러한 긍정적인 측면에서 불구하고, 사람들의 편리한 사용에 대한 욕구를 이용하여, 신종 앱 사기와 같은 범죄가 발생하고 있으며, 이를 악용하여 금전적으로 피해를 주거나 개인정보를 탈취하는 범죄로가 증가되는 추세이다. 이와 같은 앱으로 인한 범죄를 대응하기 위하여, 신종 앱 사기 범죄를 분석하고 해결하는 방안이 요구되는 실정이다. 따라서 본 논문에서는 신종 앱 사기 범죄에 악용되는 가짜 앱을 탐지하고, 공식 기관에서 제공하는 정보를 기반으로 가짜 앱과 공식 앱에 대한 대량의 정보를 공유하는 프레임워크를 개발한다. 개발한 프레임워크를 통하여, 정보를 공유한 사람들에게 가짜 앱에 대한 정보를 알려주고, 공식 기관의 앱을 확인하는 안전한 모바일 환경을 제공할 것으로 사료된다.

• Korean Journal of Remote Sensing
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• v.27 no.2
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• pp.203-211
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• 2011

Recently, information communication technologies such as smartphone or mobile app greatly affect various application fields including geo-spatial domain. And development scheme of mobile web app or hybrid app regards as the most important computing technology which is combined each advantage of mobile app and mobile web. Despite these trends, it is general case that satellite images are used for the background image for other contents services. With this motivation, hybrid app for geo-metadata as the base for dissemination and service is designed and implemented as the prototype, in this study. At the design stage, HTML5, which is the core technology on an international standardization process for hybrid app, is applied. In the implementation, PhoneGap and Sencha Touch as mobile SDK(Software Development Kit) supporting HTML5 on cross-platform in open sources are used. In prototype, some KOMPSAT-2 images covering small area and mandatory elements in geo-metafata standard are tested. As mobile industry applications and business service models based on satellite images on mobile platform are progressing and diversifying, it is expected that this approach and implemented prototype are considered as an important reference.

• Fisheries and Aquatic Sciences
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• v.6 no.1
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• pp.20-26
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• 2003

A bacterial strain was isolated from seawater to screen for phytase activities. A colony had the highest activity and was identified as an Escherichia coli strain. Using primers derived from E. coli acid phosphatase appA sequence, we cloned a 1,495 bp DNA fragment connected with the pGEM-T vector. It was over-expressed under lac promoter combined with its native promoter in E. coli $DH5\alpha$. The expression of the phytase gene occurred during late exponential growth and the intracellular phytase production was 16.9 units/ml. The yield of recombinant phytate was 412-fold higher than that of wild type E. coli K13.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.8
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• pp.3999-4005
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• 2013

We forecast that the scale of mobile market will be large scale according to the twenty million times of smart phone's user is arrived. The type of software development is being transferred into mobile-based App. or cloud computing-based service from web-based software. Currently both Google's android and Apple's IOS are known for two prominent platforms. Existing modeling techniques cannot be applied into the case of mobile application which is executed those platforms. Therefore, we suggest a modeling technique that is customized existing modeling techniques into android-based software development. That is, we propose an analysis and design techniques which are needed into android-based mobile smart environment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.668-671
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• 2014

Wiress high-speed internet network and Mobile devices such as smartphones and tablets are popular, production and consumption of information is changing from the PC environment to mobile environment. Thus, the development of related programs in the development of mobile applications than PC is dramatically increasing. In particular, A tool that is very easy to manufacture mobile app are emergence, Professionals, as well as increasing the public's interest. In this paper, when create a moblie apps, copyright and software license to be considered are examined.

• The Journal of the Korea Contents Association
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• v.16 no.6
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• pp.1-8
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• 2016

Strengthening self-directed learning ability is established as one of the goals of gifted education in Korea. In addition, it should be noted that self-directed learning can be realized in variety of ways as favorable conditions and environments are fostered to provide gifted education utilizing program. in the recent days. But, gifted learning programs for programming are programmed for information gifted student. Therefore, we have analyzed in this study the effects of improvement on self-directed learning ability of mathematically gifted student through class utilizing app inventor program for self-directed learning ability. Built up from the 4th and 5th grade to elementary math one class for gifted children complete by making math quiz, we use the app inventor to activity. The result of experiment showed very significant difference in the post-survey to less than .002 in the pre-survey in terms of three domains, which are intrinsic motivation, the openness of learning opportunities and autonomy which corresponds to sub-elements of self-directed learning ability. We could verify from the result of the study that mathematically gifted student learning program utilizing app development activity have positive effects on self-directed learning ability of mathematically gifted students.

• Journal of Satellite, Information and Communications
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• v.10 no.2
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• pp.30-33
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• 2015

In this paper, we proceeded a study on the Hybrid RF based development of the smart phone Application skin disease monitoring using CMOS camera. we proposed an image transfer technology which can use the CMOS camera and we developed the smart phone application which can be possible to use a remote monitoring for skin disease. Image transfer technology using Hybrid RF communication applied for WiFi using CMOS camera. We implemented the function which can use a remote monitoring using Wi-Fi. These suggestion can be a good example for endoscopic applications using hybrid RF based smart phone application of skin disease monitoring using CMOS camera.