• Journal of Pharmacopuncture
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• v.7 no.3
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• pp.109-114
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• 2004

Objective : This study was designed to investigate the anti-inflammatory effect of Scolopendrid Herbal-Acupuncture. Methods : Scolopendrid Herbal-Acupuncture was administered one time on everyday and A-shi points were selected. Except Scolopendrid Herbal-Acupuncture administration, other therapies(conventional body acupuncture, physical therapy and so on) were not performed at all. We evaluated the patient through Visual Analogue Scale(VAS) and Digital Infrared Thermal Imaging(DITI). Results : After 2 or 3 times of treatment, the patient showed that clinical symptoms and VAS were lessened and there was a change of temperature in DITI. Conclusions : According to the results, Scolopendrid Herbal-Acupuncture may have anti-inflammatory effects. But further studies are required to prove the exact effect.

• Journal of Haehwa Medicine
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• v.20 no.1
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• pp.153-160
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• 2011

Objective : The objective of this study is to observe the effect of Pharmacopuncture of Anti-inflammatory Herbal compound(AiC) theraphy on elbow pain Methods : The patients diagnosed as lateral epicondylitis and treated mainly with Anti-inflammatory Herbal compound(AiC). After the application of herbal acupuncture, The NRS and ROM of elbow were assessed. Results & conclusion : Symptoms of the patient such as elbow pain and dysfunction were improved after above treatments. so, it is suggested that oriental medical treatment(Pharmacopuncture of Anti-inflammatory Herbal compound(AiC)) is effective on Tennis elbow.

• Journal of Acupuncture Research
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• v.26 no.6
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• pp.91-100
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• 2009

Objectives : The objective of this study is to investigate Anti-nociceptive and anti-inflammatory effects of Clematidis Radix (CR) herbal-acupuncture on the test rats with induced acute pain. Methods : The effects of Clematidis Radix (CR)-distillates were investigated in three types of models with three different pain. Highly purified distillate of CR called CR herbal-acupuncture was injected to Zusanli ($ST_{36}$) acupoint. In the tail flick test, the CR herbal-acupuncture treatment did not show a significant effect of relieving acute pain. To investigate the anti-inflammatory effect of CR herbal-acupuncture, the second testing model'pain was induced by injecting formalin to its planter. For the last model, carrageenan was injected into tarsal joint. the medicinal effect of CR herbal-acupuncture was evaluated through the behavioral analyses such as licking time, weight distribution ratio and ankle circumference. Results : In the formalin test, the analgesic effect of CR herbal-acupuncture was more pronounced in the late phase (for 20 min after the early phase) than in the early phase (for the first 10 min post formalin injection). It was proven by weight distribution ratio testing and ankle edema testing that herbal-acupuncture of CR inhibited arthritis caused by the carrageenan. Conclusions : These results revealed that CR herbal-acupuncture was effective to alleviate the inflammatory pain and could be used as an analgesic treatment with an anti-inflammatory effect.

• Journal of Pharmacopuncture
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• v.10 no.1 s.22
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• pp.157-162
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• 2007

Objective : The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture on the metatarsal tendinitis. Methods : After the application of herbal acupuncture, the VAS and Baumgaertner's nine point scale were assessed. If there were any restraints on the ROM, ROM was also assessed alongside the previous scales. Results : 1. The pain was reduced significantly according to the VAS scale. 2. As to the assessment of satisfaction in treatment, by the Baumgaertner's nine point scale, 2 out of 3 cases scored Excellent, and one case scored Good. Conclusions : The anti-inflammatory herbal acupuncture is effective to the metatarsal tendinitis, and can be used more frequently in the clinical practices.

• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.225-233
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• 2013

Objective : The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture, acupuncture, physical theraphy, external treatment, therapeutic exercise on the osteochondritis dissecans. Methods : Anti-inflammatory herbal acupuncture and acupuncture were used to treat knee pain and gait disturbance. We evaluated the patient through VAS(visual analogue scale) daily and symptoms. Results & Conclusions : After 31 days of treatment, right knee pain was decreased from VAS 10 to VAS 4, redness, burning sensation, edemaright of right knee were decreased. And the patient could walk. Oriental medicine treatment is proved to be helpful to imporve the symptoms of the osteochondritis dissecans.

• Journal of Haehwa Medicine
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• v.18 no.1
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• pp.43-48
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• 2009

Objective: The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture on the Supraspinatus Tendinosis and subdeltoid bursitis Methods : Anti-inflammatory herbal acupuncture, A-Shi Point, Sa-am acupunture were used to treat shoulder pain. We evaluated the patient through VAS(Visual Analog Scale) daily and Physical Examinations Results & Conclusions : After 12 days of treatment, shoulder pain was decreased from VAS9 to VAS1 and the patient showed nearly full ROM(range of movement). In shoulder pain, oriental treatment is good method for pain relief and better movement.

• Journal of Haehwa Medicine
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• v.18 no.1
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• pp.109-116
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• 2009

Objective: The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture on the Complex Regional Pain Syndrome Methods : Anti-inflammatory herbal acupuncture, A-Shi Point, Sa-am acupunture were used to treat shoulder pain & ROM(range of movement)disorder, chest pain, finger's causalgic pain. We evaluated the patient through VAS(Visual Analog Scale) daily and Physical Examinations Results & Conclusions : After 42days of treatment, shoulder pain was decreased from VAS10 to VAS3, chest pain was decreased from VAS10 to VAS1.5, finger's causalgic pain was decreased from VAS10 to VAS2.5. and the patient showed that the ROM(range of movement) of shoulder was better, oriental treatment is good method for pain relief and better movement.

• Herbal Formula Science
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• v.12 no.2
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• pp.95-108
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• 2004

Objective: We made the genital organs inflammatory mice model by vaginal injection of Lipopolysaccharide(LPS), and we intended to make study about anti-inflammatory effects of Gangyeong-Tang, among oral and rectal medication and Herbal-Acupuncture treatment. Method: The female ICR(20-30g) mice were used, the temperature was controlled within $22{\pm}0.5^{\circ}C$ and water and food was not limited. The environment was manipulated to simulate 12 hours of day and 12 hours of night. After LPS injection into vagina, we confirmed on-set of inflammation. 2 days before LPS injection, we started to medicate Gangyeong-Tang in Oral and Rectal and Aqua-acupucture treatment. After 3days from LPS injection, we mesured the White Blood Cell(WBC), Interrleukin-6(IL-6), Tumor Necrosis Factor-${\alpha}$(TNF-${\alpha}$) in blood which was collected from the Retro-orbital Plexus. Results: 1. We made the genital organs inflammatory mice model by vaginal injection of LPS successfully. 2. The number of WBC was decreased significantly as we medicated Gangyeong- Tang in Oral 1g/kg dose, 3g/kg dose and Rectal 1g/kg dose, rectal 3g/kg dose. 3. The concentration of IL-6 was decreased significantly as we medicated Gangyeong-Tang in all group of the Oral, Rectal, Herbal-Acupuncture treatment. 4. The concentration of TNF-${\alpha}$ was decreased significantly as we medicated Gangyeong-Tang in Oral 3g/kg dose and Rectal 1g/kg dose, Rectal 3g/kg dose group. Herbal-Acupuncture treatment group datas showed reductive tendency. Conclusion: As a result of this experiment, we made the genital organs inflammatory mice model by vaginal injection of LPS successfully and demonstrated anti-inflammatory effect of Gangyeong-Tang.

• Korean Journal of Acupuncture
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• v.25 no.1
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• pp.197-211
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• 2008

Objectives : We studied on anti-allergic effects of Arctii Fructus Herbal Acupuncture(AFHA) and Arctii Fructus Herbal Acupuncture Solution(AF). Methods : In vivo, Animals were herbal-acupunctured AFHA at both ST36 three times for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylaxis(ASA) using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis(PCA) using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase, IL-4 and TNF-a release from RBL-2H3 cells after treatment of AF of various concentrations. Results : In vivo, AFHA pretreatments at both ST36 inhibited compound 48/80-induced ASA. PCA was inhibited by AFHA pretreatments at both ST36. In vitro, AF treatments were not affect on cell viability and inhibited b-hexosaminidase, IL-4 and TNF-a release. Conclusions : These results suggest that AFHA and AF may be beneficial in the inhibition of allergic inflammatory response.

• Journal of Acupuncture Research
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• v.35 no.1
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• pp.41-45
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• 2018

Background: Danggwisusan is a herbal medicine which is used to treat bruises, static blood, external injuries, and somatalgia in Korean medicine. The objectives of this study were to investigate whether Danggwisusan hot aqueous extract had an inhibitory effect upon inflammatory cytokine production and oxidation. Methods: Cytotoxic activity of Danggwisusan extract was examined by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay. The amount of nitric oxide produced was measured using Griess reagent. Prostaglandin E2 production was measured using an enzyme immunoassay. Inflammatory cytokines ($IL-1{\beta}$, IL-6 and $TNF-{\alpha}$) were measured by an enzyme linked immunosorbent assay. The anti-oxidative effect of Danggwisusan was measured by the 1,1-Diphenyl-2-picryl hydrazyl method. The amount of polyphenol and flavonoid contents were measured by Folin and Ciocalteauea phenol reagent and aluminum nitrate. Results: Danggwisusan hot aqueous extracts did not show significant toxicity at 10, 20, 50, and $100{\mu}g/mL$. At a dose of $100{\mu}g/mL$, Danggwisusan hot aqueous extract significantly inhibited nitric oxide and $PGE_2$ production, and significantly reduced $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ production. At a dose of $100{\mu}g/mL$, 1,1-Diphenyl-2-picryl hydrazyl free radical scavenging capability was over 50%. Conclusion: This study showed that Danggwisusan hot aqueous extract may have anti-inflammatory and anti-oxidative effects on macrophages.