• Title/Summary/Keyword: Analogy

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Application of Pharmacovigilance Methods in Occupational Health Surveillance: Comparison of Seven Disproportionality Metrics

  • Bonneterre, Vincent;Bicout, Dominique Joseph;De Gaudemaris, Regis
    • Safety and Health at Work
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    • v.3 no.2
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    • pp.92-100
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    • 2012
  • Objectives: The French National Occupational Diseases Surveillance and Prevention Network (RNV3P) is a French network of occupational disease specialists, which collects, in standardised coded reports, all cases where a physician of any specialty, referred a patient to a university occupational disease centre, to establish the relation between the disease observed and occupational exposures, independently of statutory considerations related to compensation. The objective is to compare the relevance of disproportionality measures, widely used in pharmacovigilance, for the detection of potentially new disease ${\times}$ exposure associations in RNV3P database (by analogy with the detection of potentially new health event ${\times}$ drug associations in the spontaneous reporting databases from pharmacovigilance). Methods: 2001-2009 data from RNV3P are used (81,132 observations leading to 11,627 disease ${\times}$ exposure associations). The structure of RNV3P database is compared with the ones of pharmacovigilance databases. Seven disproportionality metrics are tested and their results, notably in terms of ranking the disease ${\times}$ exposure associations, are compared. Results: RNV3P and pharmacovigilance databases showed similar structure. Frequentist methods (proportional reporting ratio [PRR], reporting odds ratio [ROR]) and a Bayesian one (known as BCPNN for "Bayesian Confidence Propagation Neural Network") show a rather similar behaviour on our data, conversely to other methods (as Poisson). Finally the PRR method was chosen, because more complex methods did not show a greater value with the RNV3P data. Accordingly, a procedure for detecting signals with PRR method, automatic triage for exclusion of associations already known, and then investigating these signals is suggested. Conclusion: This procedure may be seen as a first step of hypothesis generation before launching epidemiological and/or experimental studies.

Photonic Crystal Based Bandpass Filter Design for WDM Communication Systems (WDM 시스템에 적합한 광결정 대역 통과 필터 설계)

  • Park, Dong-Soo;Kim, Sang-In;Park, Ik-Mo;Lim, Han-Jo
    • Korean Journal of Optics and Photonics
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    • v.16 no.3
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    • pp.266-274
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    • 2005
  • We have designed photonic crystal based bandpass filters whose characteristics are suitable for WDM communication system. The filters consist of coupled point defect resonators in two-dimensional photonic crystal. The frequency response of coupled resonators has been analyzed by the coupling of modes in time, from which the design parameters for the coupled resonator filters have been extracted. For the appropriate choice of the design parameters, each resonator is treated as a lumped L-C resonance circuit, and from the analogy between the equivalent circuit and the standard L-C filter circuits, the design parameters are simply determined from the table for general filter circuit design. Based on the determined design parameters, a photonic crystal based filter has been designed and its performance has been calculated using the finite-difference time-domain method. The designed filter shows a pass band of 50GHz and 0.5 dB in-band ripple, which is suitable for typical WDM communication systems with 100GHz channel spacing.

Development of An Integrated Optimal Design Program for Design of A High-Efficiency Low-Noise Regenerative Fan (재생형 송풍기의 고효율 저소음 설계를 위한 통합형 최적설계 프로그램 개발)

  • Heo, Man-Woong;Kim, Jin-Hyuk;Seo, Tae-Wan;Koo, Gyoung-Wan;Lee, Chung-Suk;Kim, Kwang-Young
    • The KSFM Journal of Fluid Machinery
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    • v.17 no.1
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    • pp.35-40
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    • 2014
  • A multi-objective optimization of a regenerative fan for enhancing the aerodynamic and aeroacoustic performance was carried out using an integrated fan design system, namely, Total FAN-Regen$^{(R)}$. The Total FAN-Regen$^{(R)}$ was developed for non-specialists to carry out a series of design process, viz., computational preliminary design, three-dimensional aerodynamic and aeroacoustic analyses, and design optimization, for a regenerative fan. An aerodynamic analysis of the regenerative fan was conducted by solving three-dimensional Reynolds-averaged Navier-Stokes equations using the shear stress transport turbulence model. And, an aeroacoustic analysis of the regenerative fan was implemented in a finite/infinite element method by solving the variational formulation of Lighthill's analogy based on the results of the unsteady flow analysis. An optimum shape obtained by Total FAN-Regen$^{(R)}$ shows the enhanced efficiency and decreased sound pressure level as much as 1.5 % and 20.0 dB, respectively, compared to those of the reference design. The performance test was carried out for an optimized regenerative fan to validate the performance of the numerically predicted optimal design.

A Study on the Preventive Measures against Local Vibrations of Ships' Deck Panels (선체갑판(船體甲板)의 국부진동(局部振動)에 대한 방진설계(防振設計)에 관한 연구(硏究))

  • K.C.,Kim;H.M.,Kim
    • Bulletin of the Society of Naval Architects of Korea
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    • v.18 no.1
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    • pp.1-8
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    • 1981
  • To contribute to the preventive measures against local vibrations of ship's deck panels, some investigations into the prediction method of the natural frequency of the vibration of stiffened plates were done. Firstly, an analytical method based on the orthotropic plate analogy and the Rayleigh method using eigenfunctions of the Euler beam was shown, and numerical results of a regularly stiffened plate were compared with experimental results. And then, the method was extended to stiffened plates having one or two irregular stiffeners to obtain an approximate formula showing the relation between the change of the natural frequency and the size of the irregular stiffeners. The latter case was investigated for the purpose of providing a convenient design manual applicable to cure of local resonant vibrations of ships' deck panels by additional reinforcement of one or two stiffeners. In the analytical development the boundary was assumed to be rigidly supported and elastically restrained against rotation. In the experiment, however, only an extreme case i.e. simply supported boundary was investigated. The results of the investigation show that there is a fairly good conformity between the analytical results and the experimental ones in the first case, and that the approximate formula for the second case is confirmed also to be reliable for the design purpose. Considering that actual boundary conditions of deck panels in ship structures lie mostly somewhere between the simple support and the fixed, the authors discussed problems of the joint efficiency at the boundary of deck panels from the viewpoint of the practical application of the formulae.

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Flexural Vibration of Stiffened Plates in Contact with Water (보강판(補剛板)의 접수진동(接水振動))

  • K.C.,Kim;K.P.,Rhee;H.Y.,Lee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.17 no.2
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    • pp.11-16
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    • 1980
  • For vibration analysis of stiffened plates the orthotropic plate analogy is commonly accepted. As to stiffened plates in contact with water, however, there is still much uncertainty in estimation of the added mass because of the lack of direct methods. The authors, considering that for added mass of plates there are many reliable data derived theoretically or experimentally available, suggest a method to estimate the added mass of a stiffened plate by combining the mass increase factor, $\beta$, of an equivalent orthotropic plate and the correction factor, $\kappa$, for the effects of stiffeners. The latter is to be derived from systematic experimental investigations. Then, the natural frequency in water, f', can be calculated from that in air, f, by the equation $f'=f/\sqrt{1+\kappa\beta}$. To investigate practical applicability of this method, a systematic experiment was carried out with five uniaxially stiffened plates. Each of them had a plate of same size, $600mm{\times}600mm{\times}3.2mm$, but stiffeners of different size in the web-depth, 41.6mm, 51.2mm or 66.8mm and of different spacing 75mm, 100mm, or 150mm. Natural frequencies were measured under simply supported-edge conditions in both air and water, and corresponding $\kappa$ values derived. In spite of wide variations of web-depth and spcae of stiffeners, the experimental results show that the diversity of $\kappa$ values is not remarkable; mean values of $\kappa$ are 1.31 with standard deviation of 0.025 for the first modes and 1.27 with that 0.077 for the second modes. Hence, the authors concluded that the above $\kappa$ values can be used generally for the cases of uniaxially stiffened plates both sides of which contact with water, and that $\kappa$ values of general use for the cases of cross-stiffened plates may also be obtainable from similar experiments.

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An Investigation into the Hull-Girder Vibration Analysis of RO/RO Car/Truck Carriers (자동차운반선(自動車運搬船) 선체저차진동(船體低次振動)의 해석(解析))

  • K.C.,Kim;D.S.,Cho;J.H.,Chung;J.W.,Kang;S.J.,Moon;J.H.,Woo
    • Bulletin of the Society of Naval Architects of Korea
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    • v.27 no.1
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    • pp.35-44
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    • 1990
  • Most of the medium-size ships are powered by large-bore, long-stroke, slow-speed and two-stroke diesel engines in order to improve the fuel efficiency. Such a propulsion plant develops low-frequency excitation forces/moments of significant magnitude. A RO/RO car/truck carrier is also one of the cases. In this paper, the rational methods for analysis of vertical and coupled horizontal-torsional vibrations are presented. Taking account of unusual characteristics of the hull form and structural systems, the emphasis is put on modelling methods based on beam analogy, calculation of system parameters such as added mass and its center, polar added-mass moment of inertia, shear coefficient of hull sections and coupling degree in antisymmetric modes, and modal analysis of forced vibrations.

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A Study on the Optical Characteristics of Multi-Layer Touch Panel Structure on Sapphire Glass (Sapphire Glass 기반 다층박막 터치패널구조의 광학특성 연구)

  • Kwak, Young Hoon;Moon, Seong Cheol;Lee, Ji Seon;Lee, Seong Eui
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.3
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    • pp.168-174
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    • 2016
  • A conductive oxide-based sapphire glass indium tin oxide/metal electrode and the optical coating, through patterning process was studied in excellent optical properties and integrated touch panel has a high strength. Indium tin oxide conductive oxides of the sapphire glass to 0.3 A at DC magnetron sputtering method of 10 min, gas flow Ar 10 Sccm Ar, $O_2$ 1.0 Sccm the formation conditions of the thin film after annealing at $550^{\circ}C$ for 30min was achieved through a 86% transmittance. In addition, the coating 130 nm hollow silica sol-gel was to improve the optical transmittance of the indium tin oxide to 91%. For the measurement by the modeling hollow silica sol by Macleod simulation and calculated the average values of silica part to the presence or absence in analogy to actual. Refractive index value and the actual value of the material on the simulation the transmittance difference is it does not completely match the air region similar to the actual value (transmission) could be confirmed that the measurement is set to a value of between 5 nm and 10 nm.

Nonlinear Characteristics Evaluation of Tuned Liquid Damper with White Noise Amplitude (백색잡음 하중 크기에 따른 TLD의 비선형 특성 평가)

  • Woo, Sung-Sik;Lee, Sang-Hyun;Choi, Ki-Young;Chung, Lan;Park, Tae-Won
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.21 no.2
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    • pp.135-143
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    • 2008
  • In this study, it was investigated for dynamic nonlinear characteristics using dynamic data obtained by shaking table test. The design of Tuned Liquid Damper(TLD) has limitation to plan based on Tuned Mass Damper(TMD) analogy and linear wave theory. Also, while there are many studies regarding properties of TLD under harmonic load, there are not estimated for dynamic non-linear characteristics of TLD under the load that is not governed by particular frequency like a white noise. This paper investigated dynamic non-linear characteristics of TLD varied with load amplitude using a white noise and suggested equations that can estimate damping ratio, natural frequency ratio and effective mass ratio of TLD.

A New Dynamic VRF Heat Hump Simulation Including Frosting and Defrosting Models (착상 및 제상을 포함한 VRF 히트펌프의 동적 수치해석 모델)

  • Park, Noma;Shin, Jeong Seob;Chung, Baik Young;Kim, Byung Soon
    • Transactions of the KSME C: Technology and Education
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    • v.3 no.1
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    • pp.1-13
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    • 2015
  • In this study, a new dynamic VRF-type heat pump simulation model is proposed which incorporates frosting and defrosting models. Toward this end, a simple frosting model based on the perfect analogy, and lumped system based defrost model, are proposed. Then, frosting and defrosting models are incorporated into a dynamic heat pump model which adopts segment-by-segment local heat exchanger model and map-based variable speed compressor model. Thus, the model can naturally represent locally uneven frosting and defrosting on the heat exchanger surface. Developed simulation model is validated against available experimental data to show good agreement within 10% error for capacity and COP. Finally, developed dynamic heat pump model is applied to annual heating season simulation to show that seasonal COP of heat pump is degraded by 7% due to frosting and defrosting.

Change of Heat Transfer Characteristics in a Rotating Channel of Square Duct at Wall with Bleed Holes ( I ) - Effects of Rotation Speed - (회전하는 사각덕트 유로에서 벽면 유출홀에 따른 열전달 특성 변화( I ) -회전수 변화에 따른 영향 -)

  • Kim Sang In;Kim Kyung Min;Lee Dong-Hyun;Jeon Yun Heung;Cho Hyung Hee
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.17 no.10
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    • pp.898-906
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    • 2005
  • The present study has been conducted to investigate convective heat/mass transfer in the cooling passage with bleed holes. The rotating square channel has 40.0 mm hydraulic diameter and the bleed holes on the leading surface of the channel. The hole diameter of bleed hole is 4.5mm and its spacing is ( p/d:4.9) about five times of hole diameter. Exit mass flow rate through bleed holes is $10\%$ of the main mass flow rate and relation number is changed form 0.0 to 0.4. A naphthalene sublimation technique is employed to determine the detailed local heat transfer coefficients using the heat and mass transfer analogy The cooling performance is influenced by exit mass flow rate through bleed holes and Coriolis force of rotating channel for fixed Reynolds number. The heat transfer on the leading surface is decreased due to Coriolis force. However the total heat transfer is enhanced around holes on the leading surface because of trapping flow by bleeding.