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Correlation of Experimental ana Analytical Inelastic Responses of 1:12 Scale Irregular High-Rise RC Buildings (1:12축소 비정형 고층 RC 건물의 비선형거동에 대한 실험과 해석의 상관성)

  • Ko, Dong-Woo;Lee, Han-Seon
    • Journal of the Earthquake Engineering Society of Korea
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    • v.11 no.2 s.54
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    • pp.95-104
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    • 2007
  • Three types of high-rise RC building structures having irregularity in the lower two stories were selected as prototypes and were performed nonlinear static analysis by using OpenSees to verify the analysis technique and to investigate the seismic capacity of those buildings. The first one has a symmetrical moment resisting frame (Model 1), the second has an infilled shear wall in the central frame (Model 2), and the third has an infilled shear wall only in one of exterior frames (Model 3). Fiber model, which consists of concrete and reinforcing bar represented from stress-strain relationship, is adapted used for simulate the nonlinearity of members, and MVLEM(Multi vertical linear element model) is used for simulate the behavior of wall. The analytical results are simulate the behavior of piloti stories well, for example, the stiffness and yield farce of piloti stories, the up-lift of wall and the variation of lateral stiffness of column due to the variation of axial forces. Overstrength of Model 2 and Model 3 are about 2 times larger than that of Model 1. The reason of the high oversttrength and ductility of Model 2 and Model 3 is that the conservative design of Model 2 and Model 3, whose beam and column sections are the same as those of Model 1. The ductilities of Model 1 and Model 3 are slightly larger than that of Model 1 and Model 3. Model 1 and Model 3 reached mechanism condition, whereas Model 2 failed to the shear failure of shear wall and the large axial forces in columns due to large overturning moment.

EUTROPHICATION AND CHLOROPHYLL CONTENT IN THE SEAWATER OF JINHAE BAY AREA (진해만 해수의 부영양화와 클로로필 분포)

  • PARK Chung Kil
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.8 no.3
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    • pp.121-126
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    • 1975
  • Chlorophyll a content in marine phytoplankton and nutrient in seawater were determined to study the influence of eutrophication of Jinhae Bay area on primary production. Sampels were taken in the surface layer and bottom of 21 stations in Jinhae Bay including Masan Bay and Hengam Bay, ana adjacent waters such as Geoje Bay and the estuary of Naktong River for refrence during summer Period in 1974. Chlorophyll a content was ranged from $0.52\;mg/m^3\;to\;25.16\;mg/m^3$ in whole area. Mean value of chlorophyll a was the highest in Masan Bay and the lowest in GeojeBay. It was noteworthy that chlorophyll a content of Hengam Bay was not much higher than that of neighboring ares and rather lower than that of the estuary of Naktong River in spite of high phosphate content. Linear relationship between increase of nutrients and chlorophyll a was found in Masan Bay and the estuary of Naktong River where N/P ratio of nutrients was over 12. This relationship however could not be found in most area of Jinhae Bay where N/P ratio of nutrients was lower than 2 which might due to the wastewater from the Chemical Fertilizer plant. Red tide and low dissolved oxygen waters due to eutrophication were observed during summer period in Masan Bay.

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Investigation of Poultry Farm for Productivity and Health in Korea (한국에 있어서 양계장의 실태와 닭의 생산성에 관한 조사(위생과 질병중심으로))

  • 박근식;김순재;오세정
    • Korean Journal of Poultry Science
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    • v.7 no.2
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    • pp.54-76
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    • 1980
  • A survey was conducted to determine the status of health and productivity of poultry farms in Korea. Area included Was Kyunggido where exist nearly 50% of national poultry population. From this area, 41 layer and 34 broiler farms covering 21 Countries were selected randomly for the survey. When farms were divided in the operation size, 95.1% of layer and 82.3% of broiler farms were classified as business or industrial level while the rest were managed in a small scale as part time job. Generally layer farms had been established much earlier than broiler farms. Geographically 10.7% of layer farms were sited near the housing area such as field foreast and rice field. No farms were located near the seashore. The distance from one farm from the other was very close, being 80% of the farms within the distance of 1km and as many as 28% of the farms within loom. This concentrated poultry farming in a certain area created serious problems for the sanitation and preventive measures, especially in case of outbreak of infectious diseases. Average farm size was 5,016${\times}$3.3㎡ for layers and 1,037${\times}$3.3㎡ for broilers. 89.5% of layer ana 70.6% of broiler farms owned the land for farming while the rest were on lease. In 60% of layer farms welters were employed for farming while in the rest their own labour was used. Majority of farms were equipped poorly for taking necessary practice of hygiene and sanitation. The amount of disinfectant used by farms was considerably low. As many as 97.6% of lave. farms were practised with Newcastle(ND) and fowl pox(F$.$pox) vaccine, whereas only 43.6% and 5.1% of broiler farms were practised with ND and F$.$pox vaccine, respectively. In 17-32.7% of farms ND vaccine was used less than twice until 60 days of age and in only 14.6% of farms adult birds were vaccinated every 4months. Monthly expense for preventive measures was over 200,000W in 32% of farms. Only 4.9-2.7% of vaccine users were soaking advice from veterinarians before practising vaccination, 85% of the users trusted the efficacy of the vaccines. Selection of medicine was generally determined by the farm owner rather than by veterinarans on whom 33.3% of farms were dependant. When diseases outbroke, 49.3% of farms called for veterinary hospital and the rest were handled by their own veterinarians, salesmen or professionals. Approximately 70% of farms were satisfied with the diagnosis made by the veterinarians. Frequency of disease outbreaks varied according to the age and type of birds. The livabilities of layers during the period of brooding, rearing ana adultwere 90.5, 98.9 and 75.2%, respectively while the livalibility of broilers until marketing was 92.2%. In layers, average culling age, was 533.3 day and hen housed eggs were 232.7. Average feed conversion rates of layers and broilers were 3.30 and 2.48, respectively. Those figures were considerably higher than anticipated but still far lower than those in developed countries.

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Functionality of Low Molecular Weight Peptides of Acceleratedly Manufactured Anchovy Sauce with Bacillus subtilis JM3 Protease (Bacillus subtilis JM3 단백분해효소로 속성제조한 멸치액젓 저분자 peptide의 기능성)

  • Park, Jong-Hyuk;Kim, Young-Myoung;Kim, Dong-Soo;Kim, Sang-Moo
    • Korean Journal of Food Science and Technology
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    • v.37 no.5
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    • pp.827-832
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    • 2005
  • Bacillus subtilis JM3 protease from naturally fermented anchovy sauce was partially purified in 40-60% ammonium sulfate fraction. To accelerate fermentation of anchovy sauce, 2 and 4% crude B. subtilis JM3 proteases were added to 6 month-ripened anchovy sauce, and their hydrolysis degrees and amino-nitrogen contents were investigated at different storage times. Low molecular weight (LMW) peptide was purified by ultrafiltration ana gel permeation chromatography from anchovy sauce manufactured with B, subtilis JM3 protease. Anchovy sauces with 2 and 4% proteases increased hydrolysis rate by 27 and 32%, respectively. Amino-nitrogen contents of anchovy sauces fermented with 2 and 4% proteases were twofold higher than that of control. Control showed five peptide peaks on Bio-Rad P2 gel permeation chromatography spectrum, whereas anchovy sauces with 2 and 4% B. subtilis JM3 proteases showed six and seven peaks, respectively. ACE inhibitory activity was highest in peak 6 (43.75%) of anchovy sauce with 2% protease, followed by peak 5 (34.82%) of control. DPPH radical-scavenging effect was higher than 50% in all samples. Cytotoxicity was highest in peak 3 (44.12%) of control, fellowed by peak 5 (42.04%) of anchovy sauce with 4% protease.

Effect of Moving Cupping Therapy on the Post-stroke Hand Edema;Single Subject Design (뇌졸중(腦卒中) 후(後) 수부부종(手部浮腫)에 대한 주관법(走罐法)의 효과(效果))

  • Lee, Ro-Min;Lee, Sang-Hoon;Nam, Sang-Su;Kim, Yong-Suk
    • Journal of Acupuncture Research
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    • v.25 no.3
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    • pp.1-17
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    • 2008
  • Objectives : This study was designed to evaluate the effect of moving cupping therapy on the edema of paretic hand in stroke patients. Methods : The subjects were stroke patients with flaccid hemiplegia. Each subject's routine therapy program was maintained throughout single subject ABAB design. During the first week, baseline data were gathered. During the second and fourth week, intervention was provided(total 20minutes of moving cupping therapy, from contralateral to ipsilateral, distal to proximal). During third and fifth week, data were gathered with treatment withdrawn. Edema was measured with hand volumeter and measuring tape. Basically Bayesian analysis was performed using WinBUGS(ver. 1.4), for addition, visual graph and mean score were also presented for comparison between treatment(moving cupping therapy) and non-treatment. Results : The visual graph and mean score showed decrease in edema during the treatment weeks. Overall decrease in edema by moving cupping therapy was verified significantly by using Bayesian ana-lysis(95% credibility intervals). Conclusions : This study suggests that moving cupping therapy could be applicable for reducing post-stroke hand edema. Further research would be needed to establish guidelines for use.

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The effect of body lead burden on neurobehavioral function in retired lead workers (퇴직한 납 근로자들의 체내 납 부담 노출지표가 신경행동학적 기능에 미치는 영향)

  • Kim, Nam-Soo;Kim, Jin-Ho;Lee, Byung-Kook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.3
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    • pp.156-167
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    • 2010
  • To evaluate the effect of lead biomarkers including bone lead on neurobehavioral test in retired lead workers, 131 retired lead workers without any occupational exposure to organic solvent, mercury and arsenic were agreed to participate this study. For the control subjects 56 non-occupationally lead exposed subjects were recruited from same area of retired lead workers with consideration of demographic characteristics. The mean levels of blood and bone lead of retired lead workers were significantly higher than control group and there were significant correlation among other lead biomarkers. Compared with controls without occupational lead exposure, lead exposured subjects had worse performance on 10 tests out of 12 neurobehavioral tests, but only two tests(Purdue pegboard nondominant and both hand) showed statistical significance of differences. In multiple linear regression analysis of neurobehavioral tests with lead biomarkers and demographic and lifestyle variables, age was associated negatively with 11 neurobehavioral tests, whereas log-transformed ZPP was associated with Purdue pegboard(both hand) and Santa Ana manual dexterity(non-dominant hand). On the other hand, tibia lead was associated Pursuit aiming test(correct) and Purdue pegboard(dominant hand) and calcaneal lead was associated with Purdue pegboard(dominant hand). This study confirmed that among all relevant variables age was most significantly associated with the poor performance of neurobehavioral tests. The blood lead did not have any significant association with neurobehavioral tests, but tibia and calcaneal bone lead and blood ZPP showed significant association with a few tests even after more than mean 9 years from their retirements.

Effect of Informativeness on the Anxiety of Hospitalized Patients (정보제공이 입원환자 불안해소에 미치는 효과)

  • 박정옥
    • Journal of Korean Academy of Nursing
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    • v.5 no.2
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    • pp.1-10
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    • 1975
  • Every patient, who enters the hospital has a potential for becoming anxious. The control of hospitalization anxiety experienced by hospital patients is considered to be an important factor in the process of recovery from illness. This study was conducted to investigate the relationship between informativeness and hospitalization anxiety in order to give basic data for psycho-social aspect of nursing care for hospitalized patients. One hundred patients admitted to Kyungpook National University Hospital during the period of Jan. to June 1975 were sampled and divided into two groups; fifty of experimental and fifty of control group. The set of informations prepared by the investigator were given additionally to experimental group while the control group only received routine informations. Both groups were rated according to the Hospitalization Informativeness Scale which consisted of 24 questionaries and 4 categories and Hospitalization Anxiety Scale one or two days prior to discharge from the hospital. The results of the study were as follows; 1 . Mean values of Hospitalization Informativeness Scale revealed significant differences at 0.01 level with experimental group showing higher mean value. Age, sex ana educational states aid not influence the mean values of Hospitalization Informativeness Scale in both groups. 2 . The length of hospitalization did not influence significantly on the mean value of Hospitalization Informativeness Scale in both groups. 3. Rank difference correlation coefficiently between mean value of Hospitalization Informativeness Scale and the importance of information the patient's perceived were revealed significant at 0.01 level in all 4 categories such as admission discharge, treatment and nursing activities, diagnostic test, diagnosis and prognosis, health teaching for the patient and family in experimental group. While, only two categories such as treatment and nursing activities and health teaching for the patient and family in control group were revealed significant correlation. 4. Mean value of Hospitalization Anxiety Scale revealed significant difference at 0.05 level with the experimental group showing lower Hospitalization Anxiety Scale. 5. Correlation coefficiently between Hospitalization Informativeness Scale and Hospitalization Anxiety Scale were revealed significant at 0.01 level in experimental group but there was no significant correlation in control group.

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Hypertension and the Risk of Breast Cancer in Chilean Women: a Case-control Study

  • Pereira, Ana;Garmendia, Maria Luisa;Alvarado, Maria Elena;Albala, Cecilia
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5829-5834
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    • 2012
  • Background: Breast cancer is the most common cancer in women worldwide. Although different metabolic factors have been implicated in breast cancer development, the relationship between hypertension and breast cancer has not been elucidated. Aim: To evaluate hypertension as a risk factor for breast cancer in Chilean women of low and middle socio-economic status. Methods: We conducted an age-matched (1:1) case-control study in 3 hospitals in Santiago, Chile. Breast cancer cases (n=170) were histopathologically confirmed. Controls had been classified as Breast Imaging Reporting and Data System I (negative) or II (benign findings) within 6 months of recruitment. Blood pressure was measured using a mercury sphygmomanometer and standardized procedures. We used 2 hypertension cut-off points: blood pressures of ${\geq}140/90$ mmHg and ${\geq}130/85$ mmHg. Fasting insulin and glucose levels were assessed, and anthropometric, sociodemographic, and behavioral information were collected. Odds ratios and 95% confidence intervals were estimated for the entire sample and restricted to postmenopausal women using multivariable conditional logistic regression models. Results: Hypertension (${\geq}140/90$ mmHg) was significantly higher in cases (37.1%) than controls (17.1%) for the entire sample and in postmenopausal pairs (44.0% compared to 23.8%). In crude and adjusted models, hypertensive women had a 4-fold increased risk of breast cancer (adjusted odds ratio: 4.2; 95% confidence interval: 1.8; 9.6) compared to non-hypertensive women in the entire sample. We found a similar association in the postmenopausal group (adjusted odds ratio: 2.8; 95% confidence interval: 1.1; 7.4). A significant effect was also observed when hypertension was defined as blood pressure of ${\geq}130/85$ mmHg. Conclusion: A significant association was found between hypertension and breast cancer over the entire sample and when restricted to postmenopausal women. Hypertension is highly prevalent in Latin America and may be a modifiable risk factor for breast cancer; therefore, a small association between hypertension and breast cancer may have broad implications.

An Immunohistochemical ana Ultrastructural Studies on the Gut Endocrine Cells in the Hedgehog, Erinaceus koreanus (한국산 고슴도치(Erinaceus koreanus)의 장관 내분비세포에 관한 면역조직화학적 및 전자현미경적 연구)

  • Lee, Jae-Hyun
    • Applied Microscopy
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    • v.18 no.2
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    • pp.59-76
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    • 1988
  • In order to know the distribution, relative frequencies, types and morphology, endocrine cells in the intestinal tract of the hedgehog(Erinaceus koreanus) were studied by light microscopy, immunohistochemistry and electron microscopy. The results obtained are summarized as follows: 1. Two kinds of endocrine cells were demonstrated with two specific staining methods. Argyrophil cells(reactive cells for Grimelius method) were found most frequently in the intestinal region, and were infrequent in the rectum, whereas argentaffin cells (reactive cells for Masson-Hamperl method) were found most frequently in the rectum and in the other legions were infrequent. These reacting cells were mainly found in the intestinal glands, whereas a small number in the mucosa. 2. Twelve kinds of endocrine cells, gastrin(Gas)-, somatostatin (Som)-, serotonin(5-HT)-, glucagon(Glu)-, bovine pancreatic polypeptide(Bpp)-, cholecystokinin(Cck)-, secretin(Sec)-, motilin(Mot)-, glicentin(Gli)-, gastric inhibitor polypeptide(GIp)-, substance P(Sp)-, and neurotensin(Neu)-immunoreactive cells, were identified by immunohistochemical method. Gas-, Som-, 5-HT-, Glu-, Cck-, Sec-, Mot-, Gli-, Sp-, and Neu-reactive cells were observed in the duodenum, and among these Gas- and 5-HT-reactive cells were moderately found while the others were infrequent. In the jejunoileum Gas-, Som-, 5-HT-, Glu-, Cck-, Mot-, Gli-, GIp-, SP-, and Neu-reactive cells were found, and among these 5-HT- and GIp-reactive cells were moderately found while the others were infrequent. In the colon Sec-reactive cell was not detected. 5-HT-reactive cells were found most frequently and the others were infrequent in this region. 5-HT-, Bpp-, GIi- and Neu-reactive cells were found in the rectum. Among these 5-HT-reactive cells were found most frequently. 3. Electron microscopically, five types of endocrine cells, EC, ECL, D, G, A-like cell, were identified in the intestinal region. EC and ECL cells in the duodenum, EC, D and G cells in the jejuno-ileum, EC and A-like cells in the colon and EC cell in the rectum were observed respectively.

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Alterations of Blood Cholinesterase Activity and Urinary Para-nitrophenol Excretion After Exposure to Organophosphorus Insecticides (유기인제 농약 폭로로 인한 혈중 Cholinesterase 활성치와 요중 P-nitrophenol의 배설량의 변동)

  • Lee, Byung-Kook;Chung, Kyou-Chull
    • Journal of Preventive Medicine and Public Health
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    • v.7 no.1
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    • pp.115-121
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    • 1974
  • In order to evaluate the health hazard due to exposure to organophosphorus insecticides, we measured the blood cholinesterase activity ana urinary para-nitrophenol among 56 exposed subjects. They are orchard workers, rice plant workers and smithion factory workers. The clinical symptoms were also checked by physicians. We also measured the blood cholinesterase activity and urinary para-nitrophenol excretion of 20 urban people and 15 rural people who had never been exposed to organophosphorus insecticides in order to compare them according to age, sex and geographical differences. And these results were also compared with those of exposed groups. The results obtained were as follows. 1. The normal plasma cholinesterase activity and cell cholinestrase activity were $0.861{\pm}0.148\;{\Delta}pH/hr$ and $0.822{\pm}0.154\;{\Delta}pH/hr$. And normal para-nitrophenol in urine was $1.21{\pm}0.52mg/liter$. 2. No significant difference was existed in blood cholinesterase activities and urinary para-nitrophenol excre tion according to sex, age and geographical difference. 3. The plasma cholinesterase activity and cell cholinesterase activity of orchard workers, rice plant workers and smithion factory workers were $0.682{\pm}0.189\;{\Delta}pH/hr,\;0.775{\pm}0.160\;{\Delta}pH/hr,\;0.754{\pm}0.123\;{\Delta}pH/hr,\;and\;0.691{\pm}0.082\;{\Delta}pH/hr,\;0.756{\pm}0.117\;{\Delta}pH/hr,\;0.739{\pm}0.117\;{\Delta}pH/hr$. And significant decreses in blood cholinesterase activities were existed among orchard workers and smithion factory workers compared with control group. 4, The urinary para-nitrophenol excretions of orchard workers, rice plant workers and smithion factory workers were $1.33{\pm}0.66mg/liter,\;1.19{\pm}0.88mg/liter\;and\;1.37{\pm}0.67mg/liter$ and there were no significant difference between exposed groups and control group. 5. The clinical symptoms complained during and after organophosphorus insecticides exposure were frequently ranked by headache (67.7%) and vertigo (64.5%) and muscular ataxia and weakness (51.6%).

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