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Should Male Circumcision be Advocated for Genital Cancer Prevention?

  • Morris, Brian J.;Mindel, Adrian;Tobian, Aaron A.R.;Hankins, Catherine A.;Gray, Ronald H.;Bailey, Robert C.;Bosch, Xavier;Wodak, Alex D.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4839-4842
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    • 2012
  • The recent policy statement by the Cancer Council of Australia on infant circumcision and cancer prevention and the announcement that the quadrivalent human papillomavirus (HPV) vaccine will be made available for boys in Australia prompted us to provide an assessment of genital cancer prevention. While HPV vaccination of boys should help reduce anal cancer in homosexual men and cervical cancer in women, it will have little or no impact on penile or prostate cancer. Male circumcision can reduce cervical, penile and possibly prostate cancer. Promotion of both HPV vaccination and male circumcision will synergistically maximize genital cancer prevention.

Fluorescence Microscopy of Condensed DNA Conformations of Bacterial Cells

  • Suleymanoglu, Erhan
    • Journal of Microbiology
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    • v.40 no.4
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    • pp.319-326
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    • 2002
  • Cellular DNA in prokaryotes is organized in nucleic acid-protein self-assemblies referred to as the nucleoid. The physical forces responsible for its stability inside the poor solvent properties of the cytoplasm and their functional implications are not understood. Studies on the organisation and functioning of the cytosol of cells largely rely on experimental protocols performed in highly dilute solutions using biochemically purified molecules, which is not a reliable substitute for the situation existing in vivo. Our current research interest is focused on the characterization of biological and physical forces determining the compaction and phase separation of DNA in Escherichia coli cytoplasm. We have emphasized the effect of excluded volume in solutions with high macromolecular concentrations (macromolecular crowding) upon self-association patterns of reactions. The prokaryotic cytosol was simulated by addition of inert polymer polyethylene glycol (PEG) (average molecular weight 20000), as an agent which afterwards facilitates the self-association of macromolecules. Fluorescence microscopy was used for direct visualization of nucleoids in intact cells, after staining with DAPI (4',6-diamidino-2-phenylindole dihydrochloride). Addition of the crowding agent PEG 20,000, in increasing concentrations generated progressively enhanced nucleoid compaction, the effect being stronger in the presence of 0.2 M NaCl and 5 mM MgCl$\_$2/. Under these conditions, the nucleoids were compacted to volumes of around 2 ㎛$\^$3/ or comparable sizes with that of living cells.

Return to Work after an Acute Coronary Syndrome: Patients' Perspective

  • Slebus, Frans G.;Jorstad, Harald T.;Peters, Ron J.G.;Kuijer, P. Paul F.M.;Willems, J. (Han) H.B.M.;Sluiter, Judith K.;Frings-Dresen, Monique H.W.
    • Safety and Health at Work
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    • v.3 no.2
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    • pp.117-122
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    • 2012
  • Objectives: To describe the time perspective of return to work and the factors that facilitate and hinder return to work in a group of survivors of acute coronary syndrome (ACS). Methods: Retrospective semi-structured telephone survey 2 to 3 years after hospitalization with 84 employed Dutch ACS-patients from one academic medical hospital. Results: Fifty-eight percent of patients returned to work within 3 months, whereas at least 88% returned to work once within 2 years. Two years after hospitalization, 12% of ACS patients had not returned to work at all, and 24% were working, but not at pre-ACS levels. For all ACS-patients, the most mentioned categories of facilitating factors to return to work were having no complaints and not having signs or symptoms of heart disease. Physical incapacity, co-morbidity, and mental incapacity were the top 3 categories of hindering factors against returning to work. Conclusion: Within 2 years, 36% of the patients had not returned to work at their pre-ACS levels. Disease factors, functional capacity, environmental factors, and personal factors were listed as affecting subjects' work ability level.

On characteristics of environmental correction factors in the South Indian Ocean by Topex/Poseidon satellite altimetric data (Topex/Poseidon 위성의 Altimeter자료를 이용한 남인도양의 환경보정인자 특성에 관한 연구)

  • 윤홍주;김영섭;이재철
    • Korean Journal of Remote Sensing
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    • v.14 no.2
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    • pp.117-128
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    • 1998
  • Topex/Poseidon satellite, launched in Auguest 1992, has provided more 5 years of very good quality data. Efficient improvements, either about instrumental accuracy or about sea level data correction, have been made so that Topex/Poseidon has become presently a wonderful tool for many researchers. The first mission data of 73 cycles, September 1992 - August 1994, was used to our study in order to know characteristics of environmental correction factors in the Amsterdam-Crozet-Kerguelen region of the South Indian Ocean. According to standard procedures as defined under user handbook for sea surface height data processes, then we have chosen cycles 43 as the cycle of reference because this cycle has provided the completed data for measurement points and has presented the exacted position of ground track compared to another cycles. It was computed variations of various factors for correction in ascending ground track 103(Amsterdam-Kerguelen continental plateau) and descending ground track170 (Crozet basin). Here the variations of ionosphere, dry troposphere, humid troposphere, electromagnetic bias, elastic tide and loading tide were generally very smaller as a few of cm, but the variations of oceanic tide(30-35cm) and inverted barometer(15-30cm) were higher than another factors. For the correction of ocean tide, our model(CEFMO: Code d' Elements Finis pour la Maree Oceanique) - This is hydrodynamic model that is very well applicated in all oceanic situations - was used because this model has especially good solution in the coastal and island area as the open sea area. Conclusionally, it should be understood that the variation of ocean free surface is mainly under the influence of tides(>80-90%) in the Amsterdam - Crozet- Kerguelen region of the South Indian Ocean.

A NOTE ON THE SEVERITY OF RUIN IN THE RENEWAL MODEL WITH CLAIMS OF DOMINATED VARIATION

  • Tang, Qihe
    • Bulletin of the Korean Mathematical Society
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    • v.40 no.4
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    • pp.663-669
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    • 2003
  • This paper investigates the tail asymptotic behavior of the severity of ruin (the deficit at ruin) in the renewal model. Under the assumption that the tail probability of the claimsize is dominatedly varying, a uniform asymptotic formula for the tail probability of the deficit at ruin is obtained.

Trends in Polymer Separations: Better and More Information on Polymer Distributions

  • Schoenmakers, Peter
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.113-113
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    • 2006
  • Polymer separations are used to obtain information on molecular distributions (molecular-weight distribution, chemical-composition distribution, functionality-type distribution, etc.). The existing methods, such as size-exclusion chromatography are reliable, but imperfect. New methods and improvements to existing methods are being studied and some of the results will be discussed. In addition, comprehensive two-dimensional liquid chromatography allows the complete characterization of two mutually dependent distributions. LCxSEC chromatograms provide a very good qualitative impression of the distributions, but calibration is not straightforward. Finally, progress in mass spectrometry allows much better information to be obtained.

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HOMOGENIZATION OF THE NON-STATIONARY STOKES EQUATIONS WITH PERIODIC VISCOSITY

  • Choe, Hi-Jun;Kim, Hyun-Seok
    • Journal of the Korean Mathematical Society
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    • v.46 no.5
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    • pp.1041-1069
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    • 2009
  • We study the periodic homogenization of the non-stationary Stokes equations. The fundamental homogenization theorem and corrector theorem are proved under a very general assumption on the viscosity coefficients and data. The proofs are based on a weak formulation suitable for an application of classical Tartar's method of oscillating test functions. Such a weak formulation is derived by adapting an argument in Teman's book [Navier-Stokes Equations: Theory and Numerical Analysis, North-Holland, Amsterdam, 1984].

The Effect of Aroma Inhalation Method on the Preoperative Anxiety among Patients with Upper and Lower Limbs Surgery (향기요법이 상하지 수술 환자의 수술 전 불안에 미치는 효과)

  • Shin, Seung-wha;Lee, Eun-Ju;Gwak, Mi-gyeong
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.2
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    • pp.171-178
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    • 2018
  • The study was done to analyze the effects of aroma inhalation method on preoperative anxiety of upper and lower surgical patients. The research design was a nonequivalent control group non-synchronized design. The subjects were a total 60 patients of each group 30 patients that were operated on under general anesthesia for upper and lower limbs surgery. The tool of the Amsterdam preoperative anxiety information scale(APAIS), systolic and diastolic blood pressure, and pulse rate levels was measured the day before surgery. The data were analyzed by the $x^2$ test Fisher's exact test, paird t-test, and the independent t-test using SPSS 20.0. Study result indicated that Lavender aroma therapy had the effect on reduction of anxiety before surgery and reduction of blood pressure, and pulse rate levels. Therefore, the study result could be used as a scientifical data that can be applied to the nursing interventions that use the aroma inhalation method and contributing to development of the holistic nursing care.