• Journal of Chest Surgery
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• v.42 no.5
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• pp.576-587
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• 2009

Background: The up-regulation of the nitric oxide (NO)-cGMP pathway might be involved in the change of vascular reactivity in rats 3 days after they suffer acute myocardial infarction. However, the underlying mechanism for this has not been clarified. Material and Method: Acute myocardial infarction (AMI) was induced by occluding the left anterior descending coronary artery (LAD) for 30 min (Group AMI), whereas the sham-operated control rats were treated similarly without LAD occlusion (Group SHAM), The concentration-response relationships for phenylephrine (PE), KCl, acetylcholine (Ach) and sodium nitroprusside (SNP) were determined in the endothelium intact E(+) and endothelium denuded E(-) thoracic aortic rings from the rats 3 days after AMI or a SHAM operation. The concentration-response relationships of PE in the E(+) rings from the AMI rats were compared with those relationships in the rings pretreated with nitric oxide synthase (NOS) inhibitor $N{\omega}$-nitro-L-arginine methyl ester (L-NAME) or the cyclooxygenase inhibitor indomethacin. The plasma nitrite/nitrate concentrations were checked via a Griess reaction. The cyclic GMP content in the thoracic aortic rings was measured by radioimmunoassay and the endothelial nitric oxide synthase (eNOS) mRNA expression was assessed by real time PCR. Result: The mean infarct size (%) in the rats with AMI was $21.3{\pm}0.62%$. The heart rate and the systolic and diastolic blood pressure were not significantly changed in the AMI rats. The sensitivity of the contractile response to PE and KCl was significantly decreased in both the E(+) and E(-) aortic rings of the AMI group (p<0.05). L-NAME completely reversed these contractile responses whereas indomethacin did not (p<0.05). Moreover, the sensitivity of the relaxation response to Ach was also significantly decreased in the AMI group (p<0.05). The plasma nitrite and nitrate content (p<0.05), the basal cGMP content (p<0.05) and the eNOS mRNA expression (p=0.056) in the AMI rats were increased as compared with the SHAM group. Conclusion: Our findings indicate that the increased eNOS activity and the up-regulation of the NO-cGMP pathway can be attributed to the decreased contractile or relaxation response in the rat thoracic aorta 3 days after AMI.

• The Korean Journal of Medicine
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• v.93 no.6
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• pp.538-547
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• 2018

Background/Aims: The impact of left ventricular (LV) diastolic function and filling pressure on clinical outcomes in young patients with acute myocardial infarction (AMI) has been poorly studied. Therefore, the aim of this study was to investigate the impact of LV diastolic function and LV filling pressure on major adverse cardiac events (MACEs) in young patients with AMI. Methods: A total of 200 young patients (males < 45 year, females < 55 year) with AMI were divided into two groups according to the diastolic function; normal (n = 46, $39.5{\pm}5.3$ years) versus abnormal (n = 154, $43.5{\pm}5.1$ years). Results: Despite regional wall motion abnormalities, normal LV diastolic function was not uncommon in young AMI patients (23.0%). During the 40 months of clinical follow-up, MACEs developed in 26 patients (13.0%); 14 re-percutaneous coronary intervention (7.0%), 8 recurrent MI (4.0%), and 4 deaths (2.0%). MACEs did not differ between the normal and abnormal diastolic function group (13.6% vs. 10.9%, p = 0.810), but MACEs were significantly higher in the high LV filling pressure group than the normal LV filling pressure group (36.8% vs. 10.5%, p < 0.001). On multivariate analysis, high LV filling pressure was an independent predictor of MACEs (hazard ratio 3.022, 95% confidence interval 1.200-7.612, p = 0.019). Conclusions: This study suggested that measurement of the LV filling pressure (E/e' ratio) would be useful in the risk stratification of young patients with AMI. However, it would be necessary to monitor this category of patient more carefully.

• KIEE International Transactions on Power Engineering
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• v.3A no.2
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• pp.100-108
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• 2003

This paper presents the design and performance results of a pair of 6-kA high-temperature superconducting (HTS)-copper current leads, in which, over a short length at the warm end (e.g.,77K) of each HTS section, comprised of paralleled Bi-2223/Ag-Au tapes, is operated in the current-sharing mode. Because of their reliance on vapor cooling, the leads are applicable only to liquid helium cooled superconducting magnets such as those used in high-energy Physics accelerators and fusion machines. The experimental measurements have demonstrated that key performance data of the new 6-kA HTS-Copper leads agree reasonably well with those expected from design.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.8
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• pp.773-782
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• 2016

Recently, Energy Industry is in the face of such sustained Low-Growth, Energy Depletion, Climate Warming and Energy Companies bankruptcy, Various methods have been tried to break through it. In this paper, We propose Business Model of Energy New Industry in Electric Power Market after analyze background of Energy New Industry and Technology Trends. The proposed Business Model introduces Energy of Things(: EoT) Service based Advanced Metering Infrastructure, Energy Storage System(: ESS) for Frequency Regulation, Energy Prosumer using Vehicle and Grid(: VnG) and Smart City.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.52-59
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• 2020

Currently, the domestic electricity rates for houses are charged by applying a progressive level according to monthly electricity usage. Electricity rates rise sharply wWhen the amount of electricity used is large, electricity rates rise sharply. The standardized electricity rate progressive system has limitations in that it lacks consideration of the consumers' power usage patterns and limits consumers' their options. Accordingly, the Ministry of Trade, Industry and Energy and the Korea Electric Power Corporation have been demonstrating the basis of a rate system for housing, which is a method of charging electricity according to the amount of electricity used by season and time. In this paper, 10 electricity usage patterns were derived through from AMI data analysis for 5 five years of 362 apartment complexes located in metropolitan cities. The patterns were, and then applied to the existing domestic electricity rate and time-by-time rates applied to demonstrations, and by time-by-time rates in the US and Australia. The effect of the optional rate by pattern was compared and analyzed. As a result, it was confirmed that benefits occurred in five5 patterns compared to existing rate plans, and the electricity rates increased in 5 five patterns, and t. This phenomenon shows the same phenomenon withis the same as the overseas rates, including domestic rates being demonstrated.

• The Journal of Engineering Geology
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• v.19 no.4
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• pp.501-508
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• 2009

This study aims to clarify the characteristics of the physical and mechanical properties of soil-slope failure of Okcheon metamorphic zone. Soil samples were collected from 35 collapsed and uncollapsed artificial slopes along national roads. A series of laboratory experiments was carried out to examine physical and mechanical properties of soils and rocks. The results show that failure slopes have weakness of failure at 0.75 of AMI or higher, 32% of liquid limit or higher, and 31% of saturated moisture content or higher. The plastic index of failure slopes is correlated to wet density and saturated density. It turned out that failure could easily happen according to a high plastic index even if the void ratio was low. The greater the contents of bigger-sized soil, i.e. contents of sands and gravels rather than of clays, is the greater the chance to fail at the slope.

• Journal of Advanced Research in Ocean Engineering
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• v.4 no.2
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• pp.78-85
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• 2018

This paper presents a study of the effects of the free surface to marine propeller including the mesh effect of the models. In the present study, we conduct the numerical simulation for propeller performance employing the openwater test. The numerical simulations compare the meshing strategies for the propeller and show the effects on both thrust and torque. OpenFOAM is applied to solve the propeller problem and then open water performances of KCS propeller (KP505) are estimated using a Reynold-averaged Navier-Stokes equations (RANS) solver and the turbulence of the $K-{\omega}$ SST model. Unstructured meshes are used in the numerical simulation employing hexahedral meshing for mesh generation. The arbitrary mesh interfacing (AMI) and multiple rotating frame (MRF) are compared to define the best meshing strategy. The meshing strategies are evaluated through 3 classifications, i.e., coarse, medium, and fine mesh. Thus, the propeller can be performed utilizing the best mesh strategy. The computational results are validated by comparison with the experimental results. The $K_T$, $K_Q$, and efficiency of the propeller are compared to an experimental result and for all of the meshing strategies. Thus, the simulations show the influence of meshing in order to perform the propeller performances.

• JSTS:Journal of Semiconductor Technology and Science
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• v.5 no.2
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• pp.120-126
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• 2005

We have proposed a characteristic method to estimate real composition when multi component oxide films are deposited by ALD. Final atomic concentration ratio was theoretically calculated from the film densities and growth rates for $HfO_2$ and $Al_2O_3$ using ALD processed HfxAhOz mms.W e have transformed initial source feeding ratio during deposition to fins] atomic ratio in $Hf_xAl_yO_z$ films through thickness factors ($R_{HFO_2}$ ami $R_{Al_2O_3}$) ami concentration factor(C) defined in our experiments. Initial source feeding ratio could be transformed into the thickness ratio by each thickness factor. Final atomic ratio was calculated from thickness ratio by concentration factor. It has been successfully confirmed that the predicted atomic ratio was in good agreement with the actual measured value by ICP-MS analysis.

• Journal of Korean Vacuum Science & Technology
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• v.4 no.1
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• pp.1-5
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• 2000

The C 1s photoelectron energy loss spectra of tris (8-hydroxy-quinoline) aluminum (Alq$_3$) and N,N'-diphenyl-N,N'-bis (3-methyl phenyl)-1,1'-bi-phenyl-4,4'-diamine (TPD) thin films have been investigated. Two major loss structures, namely the plasmon dominated loss lines and shake-up satellites, have been observed. The shake-up spectrum of the C 1s photoelectron line is directly related to the $\pi$-$\pi$$\^$*/ energy gap of the molecule which plays an important role in organic electroluminescent materials. The molecular orbitals of Alq$_3$ and TPD and their major components, quinolime and benzene, have been calculated with the AMI semi-empirical method. The amount of the plasma-dominated loss of Alq$_3$ and TPD, which has to do with the delocalization of electrons through the molecule, was about 24 eV, alike in both cases. The main peak of the C 1s shake-up spectrum of Alq$_3$ and TPD, however, was 5.2 eV and 6.8 eV respectively. It was found that the main shake-up peak reflects more the local $\pi$\longrightarrow$\pi$$\^$*/ transition of quinoline and benzene component rather than the excitation of the whole molecule of Alq$_3$ and TPD. The C 1s shake-up spectra, however, revealed some correlation with the optical energy gap of the organic eletroluminescent materials.

• Journal of Microbiology and Biotechnology
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• v.28 no.10
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• pp.1581-1588
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• 2018

The growth of lactic acid bacteria (LAB) generates a high number of metabolites related to aromas and flavors in fermented dairy foods. These microbial proteases are involved in protein hydrolysis that produces necessary peptides for their growth and releases different molecules of interest, like bioactive peptides, during their activity. Each genus in particular has its own proteolytic system to hydrolyze the necessary proteins to meet its requirements. This review aims to highlight the differences between the proteolytic systems of Streptococcus thermophilus and other lactic acid bacteria (Lactococcus and Lactobacillus) since they are microorganisms that are frequently used in combination with other LAB in the elaboration of fermented dairy products. Based on genetic studies and in vitro and in vivo tests, the proteolytic system of Streptococcus thermophilus has been divided into three parts: 1) a serine proteinase linked to the cellular wall that is activated in the absence of glutamine and methionine; 2) the transport of peptides and oligopeptides, which are integrated in both the Dpp system and the Ami system, respectively; according to this, it is worth mentioning that the Ami system is able to transport peptides with up to 23 amino acids while the Opp system of Lactococcus or Lactobacillus transports chains with less than 13 amino acids; and finally, 3) peptide hydrolysis by intracellular peptidases, including a group of three exclusive of S. thermophilus capable of releasing either aromatic amino acids or peptides with aromatic amino acids.