• 한국축산식품학회지
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• 제42권4호
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• pp.609-624
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• 2022

Tenebrio molitor larvae, as known as edible insects, has advantages of being rich in protein, and has been recognized as a suitable alternate protein source for broiler and pig feed. Moreover, given their ability to biodegrade polystyrene, a major pollutant, Tenebrio molitor larvae has been proposed as an innovative solution to environmental problems. In the present study, we investigated the toxicity of Tenebrio molitor larvae powder (TMlp) ingested with expanded-polystyrene (W/ eps) through in vitro and in vivo experiments. The objective of this study was to determine whether TMlp W/ eps can be applied as livestock alternative protein source. For in vitro experiments, cytotoxicity test was performed to investigate the effects of TMlp-extract on the viability of estrogen-dependent MCF-7 cells. The possibility of estrogen response was investigated in two groups: Expanded-polystyrene-fed (W/ eps) TMlp group and without expanded-polystyrene-fed (W/o eps) TMlp group. For in vivo experiments, The male Sprague-Dawley rats were divided based on the dosage of TMlp administered and oral administration was performed to every day for 5 weeks. A toxicological assessments were performed, which included clinical signs, food consumption, body and organ weights, hematology, serum chemistry, and hematoxylin and eosin staining of liver and kidney. There were no specific adverse effect of TMlp W/ eps-related findings under the experimental conditions of this study, but further studies on both sexes and animal species differences should be investigated. In conclusion, TMlp W/ eps was considered non-toxic and observed to be applicable as an alternative protein source for livestock feed.

• Elastomers and Composites
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• 제59권2호
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• pp.51-63
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• 2024

Polypropylene (PP) is a commodity plastic that is widely used owing to its cost-effectiveness, lightweight nature, easy processability, and outstanding chemical and thermomechanical characteristics. However, the imperative to address energy and environmental crises has spurred global initiatives toward a circular economy, necessitating sustainable alternatives to traditional fossil-fuel-derived plastics. In this study, we conducted a series of comparative investigations of bio-based polypropylene (bio-PP) blends with current PP of the same and different grades. An extrusion-based processing methodology was employed for the bio-PP composites. Talc was used as an active filler for the preparation of the composites. A comparative analysis with the current petroleum-based PP indicated that the thermal properties and tensile characteristics of the bio-PP blends and composites remained largely unaltered, signifying the feasibility of bio-PP as a potential substitute for the current PP. To achieve a higher Young's modulus, elongation at break (EAB), and melt flow index (MFI), we prepared different composites of PP of different grades and bio-PP with varying talc contents. Interestingly, at higher biomass contents, the composites exhibited higher MFI and EAB values with comparable Young's moduli. Notably, the impact strengths of the composites with various biomass and talc contents remained unaltered. In-depth investigations through surface analysis confirmed the uniform dispersion of talc within the composite matrix. Furthermore, the moldability of the bio-PP composites was substantiated by comprehensive rheological property assessments encompassing shear rate and shear viscosity. Thus, from these outcomes, the fabricated bio-PP-based composites could be an alternative to petroleum-based PP composites for sustainable automobile applications.

• Journal of the Korean Data and Information Science Society
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• 제21권1호
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• pp.21-32
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• 2010

그래픽적 회귀는 모형에 대한 가정을 하지 않고 회귀정보를 모두 포함하는 충분요약그림을 찾아내는 분석 방법으로 모든 회귀정보를 저차원의 그림으로 표현할 수 있게 하는 데에 그 목적이 있다. 잔차산점도를 이용한 모형의 평가는 적용 범위가 선형회귀모형에 국한되는 문제점이 있기 때문에 일반화선형모형에서는 그 대안으로 주변모형 산점도를 이용하여 모형의 적절성을 평가한다. 본 논문에서는 일반화선형모형 중에서 이진반응변수를 갖는 로지스틱모형에서의 그래픽적 회귀 방법과 주변모형 산점도를 이용한 모형평가 방법을 알아본다.

• 한국멀티미디어학회논문지
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• 제7권4호
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• pp.542-549
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• 2004

전통적인 교육 환경이 지니고 있는 한계점들에 대한 대안으로써 사이버 교육은 학생과 교육기관 모두에 많은 이점을 주고 있다. 새로운 교육적 대안으로써 사이버 강좌가 성공적으로 운영되기 위하여 고려해야 할 중요한 요인들이 있다. 이 논문에서는 사이버 강좌 주요 구성 요소와 성공적인 사이버 강좌가 되기 위한 중요 요인을 분석하고자 한다. 파악된 사이버 강좌 주요 구성을 바탕으로 실제 사이버 강좌를 제작하였고, 제작된 사이버 강좌를 수강한 학생들의 관점을 설문 조사를 통하여 조사 분석하였다. 그 결과 학생들은 사이버 강좌를 4가지 관점으로 평가하고 있으며 이러한 관점에 대한 평가는 학기가 진행되는 동안 변한다는 것을 알았다. 또한 소속 단과 대학이나 학년에 따라 관점에 차이가 있는 것으로 판명되었다.

• 공업화학
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• 제29권1호
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• pp.1-9
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• 2018

미세조류는 바이오연료 생산을 위한 가장 지속가능하고 장래성이 좋은 생산 원료로 여겨지고 있다. 하지만 최근의 몇몇 전과정평가 연구에 의하면 미세조류 바이오디젤 생산, 특히 배양 단계에 많은 에너지가 소요된다는 단점이 있다. 유기탄소, 질소 및 인과 같은 영양분, 그리고 배양에 필요한 용수 비용이 전체 배양 단계의 80%까지 이를 수 있다. 본 총설에서는 최근 미세조류 배양에 필요한 인공배지의 대체용으로 사용 가능성이 높은 하폐수, 유기비료 연소배가스, 유기성 폐기물 등에 대한 최근의 활용 경향과 사용 전략에 대하여 문한 조사를 통해 요약 및 고찰하였다.

• 한국태양에너지학회 논문집
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• 제32권3호
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• pp.123-128
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• 2012

Computer simulation of buildings and solar energy systems is being used increasingly in energy assessments and design. The purpose of our work is to predict the surface temperature on inclined surfaces based on ISO-TRY typical weather data. To reach this goal, three studies were performed. They consisted of quantifying the accuracy of various well-known three models. The first type of models calculated diffuse horizontal irradiations from global ones and the second type models computed global irradiations on inclined planes from diffuse and global components on a horizontal surface. The third type of model calculated long-wave radiation and surface temperature from ISO-TRY typical weather data. The proposed model can provide an alternative to building designers in estimating the surface temperature and solar irradiation on inclined surfaces where only the typical meteorological data are available.

• Nuclear Engineering and Technology
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• 제47권7호
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• pp.895-906
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• 2015

Background: Mitigation of primary water stress corrosion cracking (PWSCC) is a significant issue in the nuclear industry. Advanced nickel-based alloys with lower susceptibility have been adopted, although they do not seem to be entirely immune from PWSCC during normal operation. With regard to structural integrity assessments of the relevant components, an accurate evaluation of crack growth rate (CGR) is important. Methods: For the present study, the extended finite element method was adopted from among diverse meshless methods because of its advantages in arbitrary crack analysis. A user-subroutine based on the strain rate damage model was developed and incorporated into the crack growth evaluation. Results: The proposed method was verified by using the well-known Alloy 600 material with a reference CGR curve. The analyzed CGR curve of the alternative Alloy 690 material was then newly estimated by applying the proven method over a practical range of stress intensity factors. Conclusion: Reliable CGR curves were obtained without complex environmental facilities or a high degree of experimental effort. The proposed method may be used to assess the PWSCC resistance of nuclear components subjected to high residual stresses such as those resulting from dissimilar metal welding parts.

• Current Optics and Photonics
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• 제4권4호
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• pp.368-372
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• 2020

We report the terahertz time-domain spectroscopy (THz-TDS) of transdermal drug delivery in human skin. The time evolution of transdermal nicotine delivery in nicotine patches was assessed by detecting the transmission coefficient of sub-picosecond THz pulses and using a semi-analytic model based on the single-layer effective medium approximation. Using commercial nicotine patches (Nicoderm CQ^®, 7 mg/24 h), THz transmission coefficients were measured to quantitatively analyze the cumulative amounts of nicotine released from the patches in the absence of their detailed specifications, including multilayer structures and optical properties at THz frequencies. The results agreed well with measurements by conventional in vitro and in vivo methods, using a diffusion cell with high-performance liquid chromatography and blood sampling respectively. Our study revealed the ability of the THz-TDS method to be an effective alternative to existing methods for noninvasive and label-free assessments of transdermal drug delivery, showing its high promise for biomedical, pharmaceutical, and cosmetic applications.

• Healthcare Informatics Research
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• 제24권4호
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• pp.387-393
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• 2018

Objectives: This paper describes an experience of implementing seamless service trials online and offline by adopting Internet of Things (IoT) technology based on near-field communication (NFC) tags and Bluetooth low-energy (BLE) beacons. The services were provided for both patients and health professionals. Methods: The pilot services were implemented to enhance healthcare service quality, improve patient safety, and provide an effective business process to health professionals in a tertiary hospital in Seoul, Korea. The services to enhance healthcare service quality include healing tours, cancer information/education, psychological assessments, indoor navigation, and exercise volume checking. The services to improve patient safety are monitoring of high-risk inpatients and delivery of real-time health information in emergency situations. In addition, the services to provide an effective business process to health professionals include surveys and web services for patient management. Results: Considering the sustainability of the pilot services, we decided to pause navigation and patient monitoring services until the interference problem could be completely resolved because beacon signal interference significantly influences the quality of services. On the other hand, we had to continue to provide new wearable beacons to high-risk patients because of hygiene issues, so the cost increased over time and was much higher than expected. Conclusions: To make the smart connected hospital services sustainable, technical feasibility (e.g., beacon signal interference), economic feasibility (e.g., continuous provision of new necklace beacons), and organizational commitment and support (e.g., renewal of new alternative medical devices and infrastructure) are required.

• 전기화학회지
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• 제25권1호
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• pp.13-21
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• 2022

There is an increasing interest in monitoring of specific biomarker for determining progression of a disease or efficacy of a treatment. Conventional method for quantification of specific biomarkers as enzyme linked immunosorbent assay (ELISA) has high material costs, long incubation periods, requires large volume of samples and involves special instruments, which necessitates clinical samples to be sent to a lab. This paper reports on the development of an electrochemical biosensor to measure total immunoglobulin E (IgE), a marker of asthma disease that varies with age, gender, and disease in concentrations from 0.3-1000 ng/mL with consuming 20 µL volume of whole blood sample. The sensor provides rapid, accurate, easy, point-of-care measurement of IgE, also, sequential monitoring of total IgE with ovalbumin (OVA) induced mice is another application of sensor. Taken together, these results provide an alternative way for detection of biomarkers in whole blood with low volumes and long-term ex-vivo assessments for understanding the progression of a disease.