• 대한미생물학회지
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• 제35권1호
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• pp.1-8
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• 2000

In order to explore the potential of ascorbic acid supplementation for the prevention and treatment of herpes simplex viral diseases, plaque reduction assays were performed. Ascorbic acid as well as copper chloride/ferric chloride were added to wells containing Vero cells infected with herpes simplex virus type 1 (HSV-1), and the infectivity of HSV-1 was determined. Since copper and iron are major transition metals in human plasma, near the normal human plasma concentrations of them were used for experiments. When Cu(II) and Fe(III) were applied, there were no significant differences between virus control and Cu(II)/Fe(III)-treated groups. But, when appropriate concentrations of ascorbic acid were added to wells, meaningful differences between control and ascorbate-treated groups were found. In the presence of Cu(II)/Fe(III) at $5.8/3.7\;{\mu}M$, 72-h treatment with ascorbate at $50\;{\mu}M$ reduced HSV-1 infections to $10.77%{\pm}4.25%$ (P < 0.001) and $500\;{\mu}M$ did to $3.06%{\pm}1.62%$ (P < 0.001). Moreover, the cytotoxicities for Vero cells at those concentrations were insignificant (P > 0.05). Current recommended dietary allowance (RDA) of ascorbic acid is 60 mg/day, and the oral intake of 60 mg/day of ascorbic acid yields plasma ascorbic acid at 45 to $58\;{\mu}M$ in a healthy adult man. Therefore, the results of this study suggest that the maintenance of appropriate level (more than $50\;{\mu}M$) of ascorbic acid in human plasma by appropriate amount (more than the RDA) of ascorbic acid supplementation may be helpful for the prevention and treatment of diseases caused by HSV -1 in an adult man. In addition, this study also suggests that ascorbic acid may be useful for the prophylaxis of fatal HSV-1 infections in neonates and the prevention of HSV-1 reactivation in immunocompromised hosts.

• Journal of Advanced Marine Engineering and Technology
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• 제18권2호
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• pp.113-121
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• 1994

Since two oil shocks in 1970s, all of engine makers have persevered in their efforts to reduce specific fuel consumption and to increase engine power rate as much as possible in marine diesel engines. As a result, the maximum pressure in cylinders of these engines has been continuously increased. It causes direct axial vibration. The axial stiffness of crank shaft is low compared to old types of engine models by increasing the stroke/bore ratio and its major critical speed might occur within engine operation range. An axial damper, therefore, needs to be installed in order to reduce the axial vibration amplitude of the crankshaft. Usually the main critical speed of axial vibration for the propulsion shafting system with a 4-8 cylinder engine exists near the maximum continuous revolution(MCR). In this case, when the damping coefficient of the damper is increased within the allowance of the structural strength, its stiffness coefficient is also increased. Therefore, the main critical speed of axial vibration can be moved beyond the MCR. It has the same function as a conventional detuner. However, in the case of a 9-12 cylinder engine, the main critical speed of axial vibration for the propulsion shafting system exists below the MCR and thus the critical speed cannot be moved beyond the MCR by using an axial damper. In this case, the damping coefficient of an axial damper should be adjusted by considering the range of engine revolution, the location and vibration amplitude of the critical speed, the fore and aft vibration of the hull super structure. It needs to clarify the dynamic characteristics of the axial vibration damper to control the axial vibration appropriately. Therefore authors suggest the calculation method to analyse the dynamic characteristics of axial vibration damper. To confirm the calculation method proposed in this paper, it is applied to the propulsion shafting system of the actual ships and satisfactory results are obtained.

• 대한지역사회영양학회지
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• 제9권4호
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• pp.491-500
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• 2004

To assess the quality of nutrient intake by area of Korean adults, a dietary survey with the 3-day record method was obtained from 324 subjects aged 40 years and older but younger than 70 (52.4 $\pm$ 8.7) living in a rural area (Ansung) and suburban area of a middle-sized city (Ansan). The quality of nutrient intake was assessed by analyzing Nutrient Adequacy Ratio (NAR), Mean Adequacy Ratio (MAR) and Index of Nutritional Quality (INQ). The average daily mean energy intakes were 1,832 ㎉ for Ansung and 1,842 ㎉ for Ansan, respectively. Daily intakes of fat for Ansung and Ansan subjects were 40.9 and 40.3 g, and those for protein were 75.1 and 73.1 g, respectively. The overall calorie: protein: fat ratio (CPF) of energy intake was 63 : 17 : 20. Daily mean intakes of protein, fat, calcium, phosphorus, iron, potassium, carotene, sodium, thiamin, and niacin were significantly higher in Ansung residents than in Ansan subjects (p < .05). The average intakes of energy, calcium, vitamin A were lower than Recommend Dietary Allowance (RDA) in both areas. Note, over 30% of the study subjects had less than 75% of RDA of calcium, vitamin A and riboflavin. The MAR was higher in Ansung than Ansan residents (0.86 and 0.85, respectively; p < .05). INQs were over 1 for most nutrients except calcium (0.87), and that of calcium and phosphorus was each significantly higher in Ansung than Ansan subjects. Based on these results, nutrient intake quality of subjects aged 40 to 69 years living in the surveyed rural area is comparable to that of semi-industrialized suburban area in Korea. Dietary deficiency in all of calcium, vitamin A, and riboflavin, however, was a common problem for both rural and suburban residents.

• 대한지역사회영양학회지
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• 제12권4호
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• pp.440-448
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• 2007

The objective of this study is to determine the effectiveness of 16-month milk consumption as a part of the health promotion community program for women in Asan. Subjects included 313 women belonging to the milk group (mean age = 69.1, range $47{\sim}89 y$) and 66 women to the control (mean age=43.6, range $20{\sim}69 y$) group. For those in the milk group, one cup (200 ml) of partially lactose-digested low-fat milk was provided everyday for 16 months. Each subject was interviewed to assess calcium intake by a 24-h recall after fasting blood was obtained for analyzing bone turnover markers, and calcaneus broadband ultrasound attenuation (BUA) was measured by quantitative ultrasound (QUS) on the left heel before and after the milk supplementation. After 16 months, the calcium intake levels changed from 55% of recommended dietary allowance (RDA) to 85% RDA in the milk group and from 73% RDA to 84% RDA in the control group. BUA were reduced from $67.9{\pm}8.1$ to $64.7{\pm}17.5$ dB/MHz for milk and from $90.4{\pm}13.0$ to $87.2{\pm}15.2$ dB/MHz for control groups. Paired t-test showed the changes of BUA for both groups (-3.24 and -3.15 dB/MHz for milk and control groups, respectively) were significant, but the two groups did not show any differences in absolute changes. When post-BUA was analyzed after age, initial BUA and menopausal status were controlled as covariates in ANCOVA model, the milk group showed significantly (p < 0.05) smaller changes than the control group (-3.50 vs -6.71 dB/MHz, respectively). According to a multiple regression analysis, milk consumption and initial BUA showed significant interaction meaning that those with lower initial BUA showed higher milk effects. We conclude that one-cup a day milk consumption for 16 month can prevent further bone loss and significantly improve calcium intake.

• 대한지역사회영양학회지
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• 제6권3호
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• pp.317-330
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• 2001

The purpose of this study was to figure out the characteristics of dietary habits and lifestyles related to the development of insulin resistance syndrome(IRS). The participants in this study were 595 adults with one or more abnormal data from a health examination and 215 normal adults. When IRS was defined as a condition in which the subjects have 2 or more abnormalities among obesity, hyperlipidemia, hypertension and hyperglycemia, the prevalence rate was 37.8%. We classified the 595 adults by the number of components of IRS components they had, the higher age and obesity index they had. Total cholesterol and glucose levels in the blood were also positively related to the number of IRS components. IRS subjects tended to practice less habitual drinking and more exercise and weight control. Coffee consumption and dining out frequency were also lower in the IRS group. An analysis of food habits by odds ratio indicated that total food score was better in the IRS group. However, it appeared that food habits such as \"frequent snacking\" and \"never rejecting offered foods\" need to be improved in IRS subjects. Other undesirable food habits were related to the consumption of eggs, dairy products, fried foods, garlic and onion. Dietary intake of Ca, Fe, riboflavin, Vit A, and energy were less than 75% of the Korean recommended allowance for more than half of the subjects. Nutrient intake was lower, Ca/P ratio from food intake was worse in the IRS group. Our results indicated that nutrition counseling for IRS need to be focused on balanced food intake to supply sufficient amount of each nutrient.nt of each nutrient.

• 대한지역사회영양학회지
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• 제7권3호
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• pp.316-326
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• 2002

This study was carried out on 178 bus drivers in the Masan area to investigate their health and nutritional status. THe nutritional status of the subjects was surveyed using a self-administered questionnaire, and blood analyses were conducted through annual health examinations in June, 1999. The results were as fellows: About 51% were classified as normal, 33% as health-concerned, and 17% as disease-suspected. The levels of total seam cholesterol were significantly higher in the over 20 year group (194.64 $\pm$ 41.42 mg/dl) than in the under 10 year group (175,00 $\pm$ 31.33 mg/dl) with respect to the length of their driving careers. Systolic blood pressure (SBP) was significantly higher in the 51 to 60 age group than in the other groups (p < 0.05) . The total seam cholesterol increased with increasing age (p < 0.001), and SBP increased with increasing Body Mass Index (BMI) (p < 0.001). Diastolic blood pressure (DBP), total cholesterol (p < 0.01), hemoglobin (p < 0.05) and glutamate-pyruvate-aminotransferase (GPT) (p < 0.05) were significantly higher in the BMI of over 20, than in the BMI under 20. The GPT was significantly higher in the BMI over 25 than in the BMI under 25. In The mean daily energy intake was 1912.7 kcal (76.5% of the RDA) ultra the protein intake was 74.3 g (106.2% or the RDA). Compared with the recommended allowance, the energy, calcium, thiamin, and riboflavin intakes were below, and the Fe, vitamin A, vitamin C intakes were above the Korean RDA. The average carbohydrate, protein, fat ratio of energy intake was 66 : 15 : 19, respectively. The length of their driving careers had a positive correlation with their ages and total serum cholesterol levels, and their ages had a positive correlation with their blood pressures, total seam cholesterol and hemoglobin levels and BMI. Their BMI had a positive correlation with their ages, blood pressures, total serum cholesterol, hemoglobin, GPT and GOT levels. The results of this study indicate that bus drivers needed regular exercise, and control of their body weights to prevent chronic diseases, and that their health status should be monitored as the length of their driving careers and ages increase.

• 한국측량학회지
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• 제11권1호
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• pp.7-18
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• 1993

비지형대상물의 전면해석을 위한 다중지점 사진측량강의 설계에는 촬영점의 기하학적 배치, 영상의 기하학적 조건, 기준점 배치 및 조정의 경중률 등 많은 문제들이 복합적으로 포함되어야 하며, 특히 좁고 긴 구조물의 내부를 측량할 경우에는 특수한 사진측량망을 필요로 한다. 본 연구에서는 구조물 내부의 전면해석에 수반되는 주요 난점들의 해결안을 제시하고 결과의 정확도 및 신뢰도의 향상을 기하고자 하였다. 이를 위해 내부의 형상과 크기에 적합한 다중사진측량망을 구성하고 광속조정법에 의하여 3차원 자료를 취득, 강의 구성요소에 따른 정확도에 미치는 영향을 고찰하였다. 아울러 본 연구에서 개발된 과대오차의 검출연산법은 사진측량 해의 신뢰도 향상에 그 활용이 기대된다.

• 한국콘텐츠학회논문지
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• 제17권1호
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• pp.50-57
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• 2017

본 논문은 대전도시철도 개통 이후 내부자료 통계분석을 통해 열차지연 원인과 문제점을 살펴보고 고위험군의 위험도를 평가하여 위험도 지수 심각도와 위험도를 측정하였다. 측정방법으로는 위험도 관리방법인 risk matrix($5{\times}5$)를 적용하여 위험도 등급을 산정하였으며, 결과에 따른 안전수준과 허용수준 범위를 분석하였다. 그 결과 차량분야가 가장 위험도가 심각하고, 다음으로 기계설비분야가 위험도를 내재하고 있는 것으로 나타났다. 특히 차량의 출입문장치결함으로 인한 출입문고장과 열차신호 및 제어장치는 심각도도 높지만, 빈도수가 매우 잦아 추가적인 사고 잠재성을 보이고 있다. 기계설비 분야의 PSD결함도 PSD의 안전문 개폐불량이 가장 위험한 것으로 나타났으며, PSD의 오취급 및 PSD의 유리파손 등도 위험도를 내포하고 있는 것으로 나타났다. 본 연구는 이러한 위험도를 내재하고 있는 사고의 빈도수를 경감하고, 심각도를 낮춰서 위험도를 예방할 수 있는 방안을 예측하여 미리 선제적으로 대비할 수 있는 분석결과를 제시함으로써 안전한 도시철도운영으로 이용자의 교통편익에 기여할 것으로 기대된다.

• 한국식품과학회지
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• 제28권5호
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• pp.940-946
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• 1996

저염 명란젓에 sulfite 염을 첨가하여 숙성 중에 일어나는 여러 가지 화학적 및 미생물 변화를 측정하여 저염 젓갈의 shelf-life에 미치는 결과를 요약하면 다음과 같다. Bisulfite 및 metasulfite 명란젓은 숙성초기에 pH가 급격하게 감소하였다가 그 후 서서히 감소하였으며 젖산 생성량도 증가하였다. 숙성이 진행됨에 따라 아미노태 질소량은 감소 경향을 나타내었으며 metasulfite 명란젓이 가장 높은 생성량을 나타내었다. Bisulfite와 metasulfite의 첨가는 숙성 후기의 VBN 및 TMA 생성 억제에 효과적이었으며, 숙성 초기의 TBA 생성을 억제하였다. Bisulfite 및 metasulfite는 fungi를 포함한 미생물의 성장을 현저하게 저해하였다. Sulfite 염 첨가시의 추정되는 shelf-life는 대조군, sulfate, bisulfite및 metasulfite인 경우 각각 16, 14, 20 및 24일이었다.

• 대한공간정보학회지
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• 제21권1호
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• pp.65-75
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• 2013

본 연구에서는 지적재조사 사업을 원활하게 추진하기 위한 기술적 기반을 조성하고, 정확한 지적정보 제공을 위해 정밀측량기술을 도입하여 지적측량 성과의 정확도를 향상시킬 수 있는 방안을 연구하였다. 이를 위해 GNSS 기술기반의 GPS, RTK-GPS, 네트워크 RTK 및 GPS_토털스테이션을 도입하여 지적도근점과 필지경계점에 대한 측량성과의 목표 정확도를 확보할 수 있는 방안을 제시함으로써 지적재조사 사업을 위한 통일된 정확도 기준을 설정하고자 하였다. 세부적인 연구로써 현행 지적측량 작업과정과 성과를 비교 분석하고, 방법별로 작업의 효율성을 분석하였다. 또한, 지적재조사 사업의 수행 시 다양한 최신 측량기술을 도입함으로써 높은 지적측량 정확도를 확보할 수 있는 측량규정을 제시하고, 지적기준점과 측지기준점을 일원화하여 지적기준점의 정확도를 향상시킬 수 있는 방안을 제시하였다.