• 제목/요약/키워드: Alcohol dependence

검색결과 153건 처리시간 0.028초

스피노달 분해와 기핵성장에 따른 상분리 과정의 광산란 패턴의 관찰 (The Observation of Scattering Patterns During Membrane Formation: Spinodal Decomposition and Nucleation Growth)

  • 강종석;허훈;이영무
    • 멤브레인
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    • 제12권2호
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    • pp.97-106
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    • 2002
  • Polysulfone (PSf/NMP/alcohol 용액과 chlorinated poly(vinyl chloride) (CPVC)/THF/Alcohol 용액에 대한 광산란 패턴을 SALS (Small angle light scattering)와 FE-SEM (field emission scanning electron microscope)을 이용하여 조사하였다. PSf 용액에서는 시간에 따라 q값의 최대 산란 강도를 보이는 광산란 거동을 나타내어 스피노달 (SD) 상분리 거동을 나타내는 반면, CPVC 용액에서는 q값이 증가함에 따라 광산란 강도가 줄어드는 핵성장 (NG) 거동을 나타냈다. 각 고분자 용액에서 상분리 중반과 후반부에서 비용매 첨가제로 사용된 알코올의 탄소수가 증가할수록 농도분극의 증가율은 줄어들었다. 또한, SD에서의 초반부의 시간에 따른 산란 강도는 비용매 첨가제의 종류에 무관하게 Cahn의 건형 이론에 잘 부합되었다. 또한, SALS 장치로 얻어진 기공크기와 전자현미경으로 얻어진 영역 크기는 상호간에 비교되었다. 20PSf/70NMP/10n-butano1 (w/w%) 용액에 대한 산란 패턴은 초기 상분리 거동에서부터 후기 거동까지 매우 선명하게 관측되었고, 초반, 중반, 그리고 후반부에 대한 SD에 대한 이론적 결과와 잘 일치하였다. 최고의 산란강도를 나타낸 각도의 크기는 n-butanol>n-propanol>methanol>no alcohol 순으로 관찰되었으며, 이 순서로 최종 형성된 막 단면의 기공 크기가 감소되는 것으로 조사되었다.

강원도지역 실업계 고등학생의 우울, 기질 및 성격특성이 음주상태에 미치는 영향 (The Influence of Depression, Temperament, Characteristic on Alcohol Drinking in Vocational High School Students in Gangwon-do)

  • 소애영;손신영;전경자;이꽃메
    • 한국학교보건학회지
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    • 제23권2호
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    • pp.181-191
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    • 2010
  • Purpose: The purpose of this study is to analyze the drinking status and to identify the impacts of depression, temperament, characteristic on drinking status in the vocational high school students. Methods: By using stratified sampling, 416 vocational high school students in Gangwon Do were selected and surveyed through self -administered questionnaires. Data were analyzed by SPSS 12.0 using $x^2$-test, t-test, ANOVA, Pearson correlation coefficient and multiple regression. Results: 88% of students had experienced of drinking. Depression was observed 59.1% of students from light to severe depression score. There was a positive correlation among drinking, the school records, novelty seeking, reward dependence and persistence. Also, there was a negative correlation among drinking, economic status, harm avoidance. The significant predictors of drinking were school records, depression, novelty seeking and persistence. Conclusion: These results suggest that vocational high school students who have the factors identified in this study are regarded as having the potential to drink. The results of this study can provide the information for the development of the health promotion program.

Cetyltrimethylammonium Bromide의 미셀화 현상에 미치는 온도 효과 및 n-알코올(프로판올, 부탄올, 펜탄올 및 헥산올) 효과 (Effects of Temperature and n-Alcohols (Propanol, Butanol, Pentanol and Hexanol) on the Micellization of Cetyltrimethylammonium Bromide)

  • 이병환
    • 대한화학회지
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    • 제38권8호
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    • pp.539-546
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    • 1994
  • 몇 가지 n-알코올들을 포함하는 수용액에서 Cetyltrimethylammonium bromide(CTAB)의 임계 미셀농도(CMC) 및 미셀 상태에서 반대이온의 결합상수$(\beta)$값을 $17^{\circ}C{\sim}41^{\circ}C$까지의 온도범위 내에서 전도도법으로 측정하였으며, CTAB 계면활성제의 미셀화에 대한 열역학 함수값($({\Delta}G^o_m,\;{\Delta}H^o_m,\;{\Delta}S^o_m,\;{\Delta}C_p)$)들을 온도에 따른 CMC 및 $\beta값$의 변화로부터 계산하였다. 또한 CTAB 계면활성제의 미셀화에 대한 n-알코올(프로판올, 부탄올, 펜탄올 및 헥산올)의 효과를 조사하기 위하여 n-알코올의 농도에 따른 CMC 및 $\beta$값의 변화를 측정하였다. n-알코올을 작은 양으로 첨가하였을 때 CMC값과 $\beta$값은 감소하였다. 그러나 과량의 n-알코올을 첨가하였을 때 CMC값은 오히려 증가하는 경향을 보였다. 이러한 현상들을 n-알코올 분자들의 미셀속으로의 가용화 및 n-알코올 분자들의 가용화로 인한 미셀의 표면전하값의 변화와 관련하여 설명하였다.

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가출청소년에서 우울증상과 애착 및 중독문제 (Depression, Attachment and Addiction Problems in Runaway Youths)

  • 고미애;홍민하;김영은;하주원;이상민;김현수
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제27권3호
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    • pp.181-187
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    • 2016
  • Objectives: This study investigated the relationship between depression, attachment and addiction problems in runaway youths. Methods: We sent a questionnaire package to 187 runaway youths in 18 adolescent shelters. The questionnaire package collected their sociodemographic data and included the Patient Health Questionnaire-9, Inventory of Parent Attachment (IPA), Korean Internet Addiction Self-Scale (K-Scale), Korean version of Alcohol Use Disorders Identification Test, and Korean version of the $Fagerstr{\ddot{o}}m$ Test for Nicotine Dependence. Results: The percentage of youth with depression was 28.8% (N=54). In the depression group, there were significantly more problematic alcohol users (53.06%, p=.0199) and significantly lower IPA scores (p=.0064). There was a significant negative correlation between depression and a IPA, and significant positive correlation between depression and the K-Scale. Conclusion: These results suggest that runaway youths with depression have more problematic alcohol drinking and attachment problems.

부산지역 남녀 대학생의 음주태도 및 음주행태 비교분석 (A Comparative Analysis of Drinking Attitudes and Behavior among College Students in Busan)

  • 강지은;최한석;최지호;여수환;정석태;김미향
    • 한국지역사회생활과학회지
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    • 제25권1호
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    • pp.19-27
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    • 2014
  • This study investigates drinking attitudes and behaviors of university students. The sample included 355 students living in Busan, Korea. The questionnaire addressed general background information (gender, age, grade and monthly pocket money), drinking attitudes (understanding the effects of alcohol on the body, stereotype of drink, age at the first drink, the drinking companion at the first drink, reasons for starting to drink, main drinking companions, major reasons for drinking, the history of drinking alone, and reasons for drinking alone), drinking behaviors (the cost of each drinking occasion, drinking amounts, the frequency of drinking, the frequency of heavy drinking, the type of alcoholic beverage, and the places of drinking). A few respondents (both male and female students) started drinking while in high school (p<0.05), and most respondents drank with friends (males: 91.0%, female: 92.2%). The main reasons for drinking were the mood for male student (46.3%) and relationships for female student (49.1%) (p<0.05). Male respondents consumed more than seven glasses of soju (39.9%), whereas female respondents, five to seven glasses (49.7%) (p<0.05). On average, the respondents drank one to two times a week (males: 47.9%, females: 51.5%) and experienced heavy drinking one to three times every three months (males: 19.1%, females: 21.0%) (p<.05). The results suggest that students with frequent alcohol consumption and heavy alcohol dependence are likely to face problems and thus require aggressive intervention strategies that target them specifically.

ADH1B와 ALDH2 활성 조합이 젊은 한국인의 음주 행동에 미치는 영향 (The Influence of ADH1B, ALDH2 Activities and Their Combination on Drinking Behaviors of Korean Young Adults)

  • 박재영;김시경;이상익
    • 생물정신의학
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    • 제17권1호
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    • pp.26-36
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    • 2010
  • Objectives : It is well-known that Korean people show distinctive drinking behaviors depending on the gene polymorphisms of alcohol metabolizing enzymes. This study examined the gene polymorphisms of ALDH2 and ADH1B and their combination on the drinking behaviors of Korean young adults. Methods : Through a follow-up survey performed for a cohort consisting of 551 university freshmen for six years, the authors attempted to identify genetic factors affecting drinking behaviors. In 2000, drinking behaviors and scores of CAGE questionnaires were assessed and ALDH2 gene polymorphism was determined with PCR-RFLP. In 2006(n= 150), AUDIT-K was assessed in addition to the above and gene polymorphism of ADH1B was determined through SNaPshot$^{TM}$ method. Results : While ALDH2*2 allele was associated with increased degree of drinking in 2000 and 2006. When both enzymes were active, the possibility to be classified into the risk group for alcohol dependence such as AUDIT-K(>12), and CAGE(>2) was high. Conclusion : The ALDH2 genotype had a significant effect on drinking behavior and degree of drinking during early adulthood. However, the combination of the active form of ADH1B and the active form of ALDH2 can be risk factor for problem drinking.

알콜중독자의 우울이 자살사고(思考)에 미치는 영향 -사회적 지지의 매개효과- (The Effect of Alcoholics' Depression on Suicidal Ideation -The Mediating Effect of Social Support-)

  • 이은희
    • 디지털융복합연구
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    • 제17권2호
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    • pp.423-431
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    • 2019
  • 본 연구의 목적은 알코올 중독자의 우울과 자살사고의 관계에서 사회적 지지의 매개역할을 규명하는 것이다. 본 연구의 연구대상자들은 DSM-IV의 기준에 의하여 알코올 의존으로 진단받은 성인들로, 현재 알코올중독치료를 위해 울산, 부산, 포항, 경주지역에 위치한 병원에서 입원 치료중인 사람들이다. 설문조사는 대상자들에게 본 연구의 목적을 설명한 후 설문조사에 동의한 사람들에게 설문지를 배포하여 자기 기입방법으로 실시했다. 이러한 과정을 통해 217부의 설문지가 분석되었다. 조사기간은 2017년 10월 01일부터 11월 01일 사이에 이루어졌다. 알코올 중독자들의 우울이 자살사고에 미치는 영향에서 사회적 지지의 매개효과를 검증하기 위해서는 3단계 매개 회귀분석과 Sobel test를 실시하였다. 연구결과, 알코올 중독자들의 우울이 자살사고에 미치는 영향에서 사회적 지지의 부분 매개효과가 검증되었다. 이러한 연구결과에 근거하여 알코올 중독자들에 대한 사회적 지지 강화를 위한 개입전략을 제안하였다.

항불안제 사용의 임상지침 (Clinical Guidelines for Anti-anxiety Drug Use)

  • 임기영
    • 생물정신의학
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    • 제1권1호
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    • pp.31-39
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    • 1994
  • Anxiety and anxiety disorders are one of the most common and most serious psychiatric problems. Anti-anxiety drugs are one of the most effective treatment method for these problems. Benzodiazepines have various side-effects and the risk of overuse and abuse. Therefore, physicians should prescribe benzodiazepines carefully. However, they should not be discouraged from prescribing benzodiazepines when they have a knowledge of the pharmacological characteristics of these drugs and there is a clear indication for their use. Generally speaking, problems of benzodiazepine use such as dependence withdrawal symptoms, and cognitive impairment are more likely to occur with high dose, long-term use(more than 4 months), in geriatric patients and patients with a history of alcohol or other sustance abuse. But long-term or high-dose use can be jusified for patients with panic disorder of agoraphobia, and medically-ill patients with persistent anxiety that cannot be otherwise treated. In summary, there cannot be a general prescribing formulation for benzodiazepine use. Physician should always make their decision based on the individual patient's risk/benefit factors.

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호스피스.완화의료에서의 사별 돌봄 (Bereavement Care in Hospice and Palliative Care)

  • 김창곤
    • Journal of Hospice and Palliative Care
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    • 제10권3호
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    • pp.120-127
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    • 2007
  • Bereavement is the state of loss resulting from death. Grief is the emotional response associated with loss, intense and acute sorrow resulting from loss. Complicated grief represent a pathological outcome involving social, physical, emotional, cognitive, spiritual morbidity. The common psychiatric disorders associated complicated grief or abnormal grief responses include clinical depression, anxiety disorders, alcohol abuse or other substance abuse, and dependence, psychotic disorders, and post-traumatic stress disorder (PTSD). Grief tasks involve a series of stage or phases following an important loss that gradually permit adjustment and recovery. Three phases of grief involve phase 1 (walking the edges), phase 2 (entering the depths), and phase 3 (reconnecting the world). For intervention to be effective they need to be individually tailored to abnormal grief reaction or unresolved grief reaction. Clear understandings of complicated grief, abnormal responses, factors increasing risk after bereavement will often enable us to prevent psychiatric disorders in bereaved patients.

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유기 가스 검지를 위한 다공질 실리콘층의 전기 저항 의존성 (Dependence of Electrical Resistance in Porous Silicon Layer for Detecting Organic Vapors)

  • 박광열;김성진;이상훈;최복길
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2002년도 하계학술대회 논문집 Vol.3 No.2
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    • pp.792-796
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    • 2002
  • In this work, porous silicon(PS) layer is used as a sensing material to detect organic gases. To do this, PS sensors with membrane structure are fabricated. The sensors were made by applying the technologies of membrane formation by anisotropic etching of silicon, and PS layer formation by anodization in HF solution. From fabricated sensors, current-voltage (I-V) curves were measured against ethanol (called alcohol), methanol and acetone gases evaporated from 0.1 to 0.5% solution concentrations at $36^{\circ}C$. As the result, all curves showed rectifying behavior due to a diode structure between Si and PS, and the conductance of sensor devices increased largely with the organic solution concentration at high voltage of 5V.

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