• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4459-4463
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• 2014

Background: Gastric cancer is the second leading cause of cancer-related deaths worldwide and infection with H. pylori is considered essential for its development. Helicobacter pylori infects more than 50% of the world's population with higher prevalence in developing countries than developed countries. The prevalence of H. pylori varies in different societies and geographical locations. The objectives of this study were to estimate the seroprevalence and determine the risk factors of H. pylori infection in dyspeptic patents in Ethiopia. Materials and Methods: A cross-sectional study involving 209 dyspeptic patients was carried out from February 15 to April 30, 2013. Five to ten ml venous blood was collected from each dyspeptic patient and analyzed for detection of Helicobacter pylori immunoglobulin (IgG). The socio-demographic characteristic, hygienic practices, alcohol consumption, sources of drinking water and types of latrine were also obtained with a pre-tested questionnaire. Results: The overall seroprevalence of Helicobacter pylori was 72.2%. There was statistically significant difference in the prevalence of H. pylori among age groups (p=0.02). Seroprevalence of H. pylori was higher in those patients who used unprotected surface water (76.4%) than those with access to piped tap water (65.9%). There was also statistically significant differences in prevalence of H. pylori with the habit of hand washing before meal (p=0.01) and alcohol consumption (p=0.001). Conclusions: The prevalence of H. pylori was high in the study area and increased with age of dyspeptic patients. Alcohol consumption and the type of drinking water are risk factors that have associations with the prevalence of H. pylori. Molecular epidemiological techniques can show a true picture of H. pylori and improvement in the drinking water quality is recommended.

• Nutrition Research and Practice
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• v.13 no.5
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• pp.425-433
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• 2019

BACKGROUND/OBJECTIVES: The International Agency for Research on Cancer defined alcohol beverages and acetaldehyde derived from alcoholic beverages as a Group 1 carcinogen to humans. However, the association between alcohol consumption and gastric cancer risk has been controversial in Korean. We assessed the relationship between alcohol consumption and gastric cancer risk in Korea through a case-control study. SUBJECTS/METHODS: From 2 hospitals, a total of 316 cases with gastric cancer (208 men, 108 women) were selected and matched to 316 controls by sex and age (${\pm}5years$) during the same duration. The current status, frequency, and amount of alcohol consumption for a year three years ago were assessed by trained interviewers. RESULTS: Alcohol consumption status and frequency did not show any significant association with gastric cancer risk. However, high alcohol consumption (${\geq}20g/day$ for women or ${\geq}40g/day$ for men) significantly increased the risk of gastric cancer (odds ratio (OR) 1.73; 95% confidence interval (CI) 1.05-2.85). Gastric cancer risk was strongly positively associated with alcohol consumption of ${\geq}20g/day$, especially in women (OR 5.62; 95% CI 1.32-23.81). CONCLUSION: The results from this study suggest that excessive alcohol consumption rather than the current status or frequency of alcohol consumption contributes to the increased risk of gastric cancer, especially in women.

• Journal of Haehwa Medicine
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• v.20 no.2
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• pp.105-109
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• 2012

Objective: The purpose of this study was to show the effects Oriental medicine and treatment for aftereffects of Central pontine myelinolysis (CPM). Methods: The 52-year-old woman suffering from CPM showed symptoms of weakness of both extremities, dysarthria, dysphagia and gait disturbance. We treated the patient with oriental medical therapy. Results: After the treatments, overall symptoms of CPM were improved. Conclusions: This study suggests that oriental medical therapy is probably effective in the treatment of CPM.

• Journal of Preventive Medicine and Public Health
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• v.35 no.2
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• pp.123-128
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• 2002

Objective : To examine the relationship between cigarette smoking, alcohol and cancer mortality in men in the Kangwha cohort after 12 years and 10 months of follow up. Methods : The subjects consisted of 2,681 men in the Kangwha cohort aged over 55 in 1985. Number of deaths and the time to death front all cancers and other cause were measured and the data for the smoking and drinking habits were obtained from the baseline survey data in 1985. All subjects were categorized into four groups according to their smoking habits: non-smokers, ex-smokers, mode(ate-smokers (1-19 cigarettes per day), heavy-smokers ($\geq$20 cigarettes per day). In addition, they were also categorized according to their drinking habits: non-drinkers, light-drinkers ($\leq$1 drink per week), moderate-drinkers (<3 drinks per day), heavy-drinkers ($\geq$3 drinks per day). The cancer specific death rates were calculated according to their smoking and drinking status. The adjusted risk ratio for all cancer deaths according to their smoking and drinking status were estimated using the Cox's proportional hazard regression model. Results : Using nonsmokers as the reference category, the adjusted risk ratio for all cancer deaths were 1.573(95% CI=1.003-2.468) for heavy-smokers. For lung cancer deaths, the adjusted risk ratios were 3.540(95% CI=1.251-10.018) for moderate-smoker and 4.114(95% CI=1.275-13.271) for heavy-smokers. Compared to non-drinkers, the adjusted risk ratio for stomach cancer was 2.204(95% CI=1.114-4.361) for light-drinkers. Conclusion : Smoking is the most significant risk factor for cancer deaths particularly lung cancer.

• The Journal of Korean Academy of Sensory Integration
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• v.13 no.1
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• pp.23-31
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• 2015

Objective : The aim of this study was to investigate the correlation between problem drinking and sensory processing features in college students. Methods : From April to June in 2015, mentally healthy 162 college students were completed the questionnaire for problem drinking and sensory processing features. Both Adolescent/Adult Sensory Profile and Alcohol Use Disorder Identification Test-Korean were used as measurements for correlation. Results : Depends on the existence of the problem drinking, there was no statistical differences between groups in sensory processing features. In group of problem drinking, the result indicated the positive correlation between problem drinking and sensory processing feature (r=.195). Conclusion : Problem drinking had significant relationship with sensory sensitivity. Therapists should understand the features of college students with problem drinking. It would be desirable to develop a proper evaluation and intervention programs for these people.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.6
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• pp.934-942
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• 2014

The purpose of this study was to investigate factors affecting problematic drinking by university students in the Chuncheon area. Lifelong drinking rate of subjects was 98.1%. Problematic drinking rates according to AUDIT (alcohol use disorders identification test) were as follows: 21.3% 'no problem', 58.0% 'at-risk drinking', 10.0% 'alcohol abuse' and 10.7% 'alcohol dependence'. Research has shown that problematic drinking is more prevalent among freshmen, early drinkers, those with hypochondria, and students who are less satisfied with their campus life or whose own parents are frequent drinkers. It has been shown that more serious problematic drinking is associated with higher 'positive alcohol outcome expectancies' and 'coping motives for drinking', and 'recognition level of drinking cultures' is considered less desirable. Multiple regression analysis revealed that 'coping motives for drinking' was the most significant variable affecting the problematic drinking of university students. Developing and fostering various alcohol-reducing programs that largely focus on 'coping motives for drinking' will greatly contribute to solving problematic drinking.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.313-325
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• 1996

Experiments were undertaken to examine the ability of selenium to protect against alcohol and/or paraquat-induced hepatotoxicity and to examine the additive effect between alcohol and paraquat. Protective effect against hepatotoxic functions was measured in serum from alcohol(15% v/v), paraquat(200ppm), alcohol and paraquat, and combination of sodium selenite(4ppm) in drinking water-fed guinea pigs ad libitum for 4 weeks. A total of 68 healthy 7-weeks-old male animals were assigned at random to 8 treatment groups(9~13 animals/group). Body and liver weight losses, and high serum concentrations in aspartate aminotransferase(AST), alanine aminotransferase(ALT, in only paraquat group), $\gamma$-glutamyltranspeptidase($\gamma$-GTP), cholesterol(Cho), creatinine, blood urea nitrogen(BUN), total bilirubin(TB), direct bilirubin(DB), total protein(TP), albumin and globulin as well as low values in alkaline phosphatase(ALP) and glucose were produced in a groups of alcohol or paraquat-fed. These values were not potentiated in a group given the combination of alcohol plus paraquat. Morphological changes in the liver were also observed in the alcohol or paraquat-fed group. Lipid droplet and cell swelling in the hepatocytes were observed in alcohol-fed guinea pig, especially Mallory's hyaline arounded hepatic vein. In the paraquat-fed guinea pig, lipid droplet, pyknosis and karyolysis were observed. When alcohol or paraquat was combined with selenium-fed, hyperplasia of Kupffer cell in liver were observed. However, the mean ALT, $\gamma$-GTP, Cho, BUN, TB, TP, albumin and globulin values were lower in groups given the combination of alcohol and/or paraquat plus selenium, compared with groups given alcohol and/or paraquat. Also, the ratio of liver weight to body weight and ALP values(exception of paraquat plus selenium group) were increased by selenium. These results suggest that an adequate selenium confers marked protection against alcohol and paraquat-induced hepatotoxicity.

• Korean Journal of Adult Nursing
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• v.26 no.1
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• pp.78-88
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• 2014

Purpose: The purpose of this study was to construct a structural equation model (SEM) that would describe the binge drinking among Korean undergraduate students. Methods: Model construction was based on the theory of planned behavior and prototype/willingness model, using the variables; intention, attitude, descriptive norm, and prototype perception of binge drinking, alcohol use disorders identification test (AUDIT), and binge drinking behavior. The analysis of data was done with both SPSS 20.0 for descriptive statistics and AMOS 20.0 for SEM. Results: The binge drinking intention was found to have a significantly direct effect in influencing binge drinking behavior. In addition, attitude, descriptive norm, and prototype perception of binge drinking were found to have a significantly direct effect in influencing binge drinking intention. The final modified model yielded $x^2$=374.2 (p<.001), df=174, $x^2/df$=2.15, GFI=.87, AGFI=.82, NFI=.89, PNFI=.73 RMSEA=.07, and CFI=.94. Conclusion: This study constructed a model that addressed the factors related to binge drinking and described the relationship of these factors in influencing binge drinking among Korean undergraduate students. Findings from this study can contribute to designing appropriate prevention strategies to reduce problem related binge drinking in undergraduate students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.183-192
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• 2018

The purpose of this study was to compare female nursing college students with respect to drinking habit, drinking motives, and drinking problems. (Ed note: confirm edited version; original is a bit unclear in intent) Subjects include nursing college students in some areas, and data were collected between April and May, 2018. A total of 181 questionnaires were analyzed. The frequency analysis was used to examine the differences between the normal and drinking-problem groups. Pearson's correlation analysis was used to examine the correlations of drinking problems, and logistic regression analysis was used to analyze the factors related to drinking problems. The findings show that the frequency of drinking, rate of drinking, drinking motives, life stress, and prior experiences with drinking problems recorded a high risk ratio for drinking problems. Specifically, the group with a drinking frequency of 2~3 times per week showed a risk ratio that was 21.53 times higher than the group with a drinking frequency of 1~4 times per year. The group of higher drinking motives recorded a risk ratio that was 5.96 times higher than the group of lower drinking motives. The group of higher experiences with drinking problems showed a risk ratio that was 8.80 times higher than the group of lower experiences with drinking problems. In conclusion, the frequency of drinking, rate of drinking, drinking motives, life stress, and experiences with drinking problems were factors highly related to the drinking problems in female college students. The results highlight that careful evaluation of drinking habit of college students are needed. Moreover, periodic temperance education and programs designed to identify and prevent drinking problems are necessary to lower the risk of developing drinking problems and promote a safe drinking culture.

• The Journal of Korean Society for School & Community Health Education
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• v.19 no.1
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• pp.111-125
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• 2018

Objectives: The aim of this study was to identify differential impacts on smoking and drinking behaviors according to early menarche. Methods: 31,277 Korean female adolescents who had undergone menarche were included. Among them, 1,822 participants(5.8%) who experienced menarche in elementary school under 4th grade were assigned to early menarche group and others were was assigned normal menarche group. Using 11th(2015) Korea Youth Risk Behavior Web-based Survey, logistic regression analysis was conducted. Results: Adjusted confounding variables were analyzed and it was found that both drinking and smoking behaviors were higher in early menarche group. The participants with early menarche showed higher risk of non-daily smoking(OR=1.39, 95%CI=1.18-1.63), light daily smoking(OR=1.64, 95%CI=1.14-2.35) and moderate-to-heavy daily smoking(OR=3.15, 95%CI=2.02-4.92). Also, in the drinking behaviors, the risk of light and heavy drinking was higher than those of normal menarche group. Conclusions: Finding of this study showed Early menarche adolescents were associated with heavy smoking and drinking behaviors compared to normal menarche. Further studies are needed more evaluations.