• Proceedings of the Korean Society of Computer Information Conference
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• 2020.07a
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• pp.143-144
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• 2020

본 연구에서는 사이즈코리아에서 2015년 이루어진 제7차 인체치수조사 데이터 중 60대 남성의 치수와 2014년에 이루어진 고령자인체치수조사 데이터의 70대와 80대 남성의 치수를 분석하여 신체적인 노화가 주로 나타나는 연령 구간과 노화에 따른 노년 남성 체형의 변화에 대한 특성을 살펴보고자 하였다. 노년 남성의 경우 대체로 66-68세 사이와 75-77세 사이 그리고 84-85세 사이에 급격한 노화현상이 나타나게 되고 60대와 70대에는 서서히 노화가 진행되다가 대체로 80대에 들어서면서 노화가 심화되어 신체적으로 체형의 변화가 급격히 나타나게 된다. 연령의 증가에 따른 노화의 현상으로 신체의 둘레, 너비, 높이 등에서는 변화가 심화되나 둘레, 너비, 높이에 비해 두께의 경우에는 변화가 크지 않은 것으로 분석되었다. 또, 노년 여성의 경우에는 등이 굽는 현상이 나타났으나 노년 남성의 경우에는 여성과는 반대로 뒤로 젖혀진 체형이 나타나 차이가 발견되었다. 따라서 의복패턴 제작 시 앞중심길이와 등길이 설정에 있어서 노년 여성과는 반대로 등 길이를 짧게 하는 패턴상의 수정이 요구된다.

• Journal of Integrative Natural Science
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• v.16 no.3
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• pp.75-80
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• 2023

Bipolar disorder is a mental illness characterized by extreme mood and behavioral swings, such as highs of euphoria and lows of depression. It is a socially significant disorder in which people with the disorder experience intense mood swings and, for those with severe bipolar disorder, it is even difficult leading a normal life. High stress levels in people with mental illness can lead to neuroendocrine disruption, and it is strongly linked to aging. When the neuroendocrine system becomes vulnerable to these mental illnesses and stress, it is likely to accelerate aging. And it's the epigenetic clock that can measure the extent of this accelerated aging. The Epi clock, a pan tissue clock, measures aging through DNA methylation, and the degree of methylation is modified and changed by environmental conditions in the body. Therefore we wanted to check the changes in the epigenetic age of the patients with bipolar disorder. While we found no significant differences in epigenetic age, we did confirm the possibility that people with bipolar disorder have different methylation than normal people. We also found that the EPIC array data fit better on the Epi clock than on the Horvath clock with age-accelerated data from normal people.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.16 no.9
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• pp.842-850
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• 2003

The suspension insulators are subjected to harsh environments in service for a long time. The long-term reliability of tile insulators is required for both mechanical and electrical performances. This study describes some basic performance tests and accelerated aging test by cool-heat cycling methods and thermal mechanical performance test methods on alumina porcelain insulators (new and aged) used for transmission line in KOREA. There was no fail in electrical and mechanical performance tests such as a high voltage strength, a flashover voltage, and an impact strength in all samples. But in the case of accelerating aging tests which have above 9$0^{\circ}C$ temperature gradient, fracture phenomena was happened by a thermal shock in tile aged sample(sample A) with low alumina porcelain body. It was indicated that sample A was more severely aged than other samples. According to results of HRB test and microstructural analysis, it was reasoned that insulator bodies with the matrix reinforced with alumina crystalline phase have advantages over the suppression of crack advance. And cool-heat aging and mechanical thermal ageing tests shows that a temperature gradient is more effective to accelerating than a cycling number.

• Molecules and Cells
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• v.39 no.9
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• pp.680-686
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• 2016

Uncoupling proteins (UCPs) are mitochondrial inner membrane proteins that function to dissipate proton motive force and mitochondrial membrane potential. One UCP has been identified in Caenorhabditis elegans (C. elegans), namely UCP-4. In this study, we examined its expression and localization using a GFP marker in C. elegans. ucp-4 was expressed throughout the body from early embryo to aged adult and UCP-4 was localized in the mitochondria. It is known that increased mitochondrial membrane protential leads to a reactive oxygen species (ROS) increase, which is associated with age-related diseases, including neurodegenerative diseases in humans. A ucp-4 mutant showed increased mitochondrial membrane protential in association with increased neuronal defects during aging, and the neurons of ucp-4 overexpressing animals showed decreased neuronal defects during aging. These results suggest that UCP-4 may be involved in neuroprotection during aging via relieving mitochondrial membrane protential. We also investigated the relationship between UCP-4 and innate immunity because increased ROS can affect innate immunity. ucp-4 mutant displayed increased resistance to the pathogen Staphylococcus aureus compared to wild type. The enhanced immunity in the ucp-4 mutant could be related to increased mitochondrial membrane protential, presumably followed by increased ROS. In summary, UCP-4 might have an important role in neuronal aging and innate immune responses through mediating mitochondrial membrane protential.

• Korean Journal of Adult Nursing
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• v.20 no.2
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• pp.280-295
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• 2008

Purpose: This ethnography in communication aimed to explore the changes in consciousness on time and temporality as an elderly became older. This study focused on time as a primary message systems of Edward Hall. Methods: The assumption of the study was that the aging body as an expression of biological time is a meta of physical, personal, and social time. Data were collected from iterative fieldwork in a clan between Jan, 1990 and April, 2007. The key informants were 13 women and men aged 70 years old or more at the beginning of study. Changes in physical time and temporality as the women's body declined in its physical function was analyzed. As the cultural context, informants' every life and the history of the clan were also analyzed. Results: The meta-time of the informants were constituted as follows: In the low-contextual dimension, physical time perceived as longer and personal time perceived as shorter than they were young; In high-contextual dimension, informant and residents had a polychronic perspective and aged-centered time perspectives.; In the supernatural dimension of time, sacred time were reinforced by rituals. Informants extended temporality to their springs' world and ancestors' world. Conclusion: As the informants recognized slugged body movements and time-limited present life, their views on their life world towards the future of spring and of the sacred world of ancestors. Thereby, their identity as a member of a clan was reinforced. This result informed us on what we should focus on when caring with older women.

• Nutrition Research and Practice
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• v.8 no.2
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• pp.192-197
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• 2014

BACKGROUND/OBJECTIVES: The body composition changes in aging increased the risk of metabolic disorder. Recent dietary studies have increasingly focused on the correlations between dietary patterns and chronic diseases to overcome the limitations of traditional single-nutrient studies because nutrients in food have complex relations that interact. SUBJECTS/METHODS: This study was conducted to classify a dietary pattern among Korean elderly using cluster analysis and to explore the relationships between dietary patterns and body composition changes in Korean elderly aged 65 years or older. The study subjects (n=1,435) were individuals who participated in the Korean National Health Examination and Nutrition Survey (KNHANES) in 2011. RESULTS: There were three dietary patterns derived by cluster analysis in this study: 'Traditional Korean' (37.49% of total population), 'Meat and Alcohol' (19.65%) and 'Westernized Korean' (42.86%). The (1) 'Traditional Korean' pattern was characterized by high consumptions of white rice and low protein, low fat, and low milk products, while (2) 'Westernized Korean' pattern ate a Korean-style diet base with various foods such as noodles, bread, eggs and milk, (3) 'Meat and Alcohol' pattern had high consumptions of meat and alcohol. In body composition changes, compared with the 'Traditional Korean' pattern, the 'Meat & alcohol' pattern was associated with a 50% increased risk of having elevated BMI ($kg/m^2$), 'Westernized Korean' pattern was associated with a 74% increased abnormality of ASM/Wt (kg) by logistics analysis. Most of the Korean adult population continues to follow ether a traditional Korean having beneficial effects for successful aging. However, the 'Traditional Korean' pattern showed low protein intake (0.7 g/kg), calcium intake, and vitamin D intake as well as low of appendicular skeletal muscle mass (ASM (kg)) among 3 groups. CONCLUSIONS: Considering the low ASM, consumption of protein, calcium and vitamin D should be increased for Korean elderly health body composition.

• Journal of agricultural medicine and community health
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• v.18 no.1
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• pp.65-75
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• 1993

This study was conducted to compare the frequency and to find epidemiologic characteristics of the diseases by analyzing the results of routine first health examination for partial healthy public officials. The total number of the examined was 1.128(876 male, 252 female) The results were as follow; 1. The prevalence rate of suspicious disease was liver disease 5.9% hypertension 5.4%, hyperlipemic disease 3.8%, pulmonary tuberculosis 1.2% by order. 2. The mean systolic blood pressure and diastolic blood pressure showed increasing trend by age increasing. The mean of blood pressure in man was rather higher than that in woman. 3. The prevalence rate of suspicious borderline hypertension increased by aging. And the distribution of high cholesterol group and over than overweight group increased by aging. 4. In male, significant relation among age, systolic blood pressure, diastolic blood pressure, relative body weight was found. And significant relation between total cholesterol level and relative body weight was found. In female, age and relative body weight was related to systolic blood pressure, diastolic blood pressure and total cholesterol level. 5. According to the retrospective follow-up for those who had suspicious disease, correspondence rate of results was 5.2% in circulatory disease and 1.5% in liver disease.

• Journal of Haehwa Medicine
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• v.8 no.1
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• pp.711-726
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• 1999

Aging in the life form occurs due to a gradual progression of the body growth and degeneration. Morphological and functional changes in the body decreases the adaptation and prevention capacity leading into the decline of a life force. Various studies have been released to examine the anti-aging effects of herbal prescriptions. This experiment has chosen Boganhwan which is used for the deficiency of the liver function and studied the anti-aging factors by examining the biotransformation enzymes. The following results were obtained in this study: 1. Hepatic lipid peroxide activity was significantly suppressed in the experimental group treated with Boganhwan for 2 weeks at the dosage of 350mg/kg, while other dosage groups did not present much changes. 2. Insignificant changes were shown for the cytochrome P-450 level, aminopyrine demethylase, and aniline hydroxylase (AH) activities. Cytochrome P-450 do not appears to be a part of the detoxification scheme. 3. Boganhwan decoction treated group showed most significant increase of superoxide dismutase (SOD), catalase, superoxide, and glutathione activities at the concentration of 350mg/kg and 500mg/kg. 4. Glutathione S-transferase and glutathione made most significant increase at the decoction concentration of 350mg/kg and 500mg/kg compared to the control group. 5. Hepatic glutathione concentration, protein bound-SH, and nonprotein bound-SH made most significant increase at the decoction concentration of 350mg/kg and 500mg/kg compared to the control group. From the above results, Boganhwan decoction played an important role in eliminating foreign substances in the body excluding cytochrome P-450 enzyme system. Thus, Boganhwan decoction can provide substantial aid in preventing and treating senile related illnesses.

• Korean Journal of Applied Biomechanics
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• v.30 no.1
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• pp.121-129
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• 2020

Objective: This study was conducted with the aim of verifying the effectiveness of the duocock exercise, which is being utilized at the newly developed site to promote balance maintenance, basic physical strength and muscle strength among various age groups, in order to prevent fall and successfully age. Method: In this study, we conducted the duocock Exercise Program for 12 weeks (twice a week for an hour) for 10 senior citizens aged 65 or older (68.8±4.76 yrs, height: 15±6.00 cm) using Western-based health institutions in Daejeon, and compared the pre- and post- effects on basic physical strength and posture balance. All the data obtained from this study were used in statistical program SPSS 24 to perform paired t-test. The significance level for all statistical analyses was set at the level of p<0.05. Results: The 12 week duocock program showed statistically significant improvements in lower extremity muscle strength, equilibrium, agility, balance, and coordination in the basic fitness factors underlying successful aging (p<0.05). In addition, the trunk imbalance, which acts as a factor of falls and body balance, was statistically significant (p<0.05) and the posture balance of the sagittal plane also showed the effect of proper body adjustment. Conclusion: Based on the results of this study, duocock provides a new exercise program in the form of a sustainable sport as a two-handed exercise, and is very effective for the elderly to improve their basic physical strength as well as to control postural imbalances, strengthen and increase muscle strength.

• Korean journal of applied entomology
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• v.38 no.2
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• pp.129-138
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• 1999

This study was carried out with two types of silkworm, Bombyx mori, adults having different life span: long life span (adult living for more than fifteen days; LLS), and short life span (adult living less for than five days; SLS). The fine structures of fat body cells in the young and the senescent males and females were compared in an attempt to elucidate the aging physiology of the silkworm adult. In SLS, there were many rough endoplasmic reticula (RER) and glycogen granules in the female cytoplasm, whereas the smooth endoplasmic reticula (SER) were observed in the male cytoplasm. Also in SLS, the mitochondria were swollen and had many poor osmiophillic inclusions (fatty degeneration) at three days after emergence. In LLS, compared to SLS, comparatively normal mitochondria and nuclear membrane were observed in even five day old female. In fifteen day old LLS female, however most of cell membranes were disappeared and mitochondria were abnormally expanded. Many fat granules were observed in the cytoplasm of ten day old male (LLS) which died with full autophagic vacuole (AV) collapsed at fifteen days. Therefore, it is suggested that SLS type is recommended for the study of aging tissue, because it is easier to monitor the changes in tissue structure.