• Biotechnology and Bioprocess Engineering:BBE
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• 제6권4호
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• pp.231-236
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• 2001

How much do we know about the biology of aging from cell culture studies Most normal somatic cells have a finite potential to divide due to a process termed cellular or replicative senescence. A growing body evidence suggests that senescence evolved to protect higher eu-karyotes, particularly mammals, from developing cancer, We now know that telomere shortening due to the biochemistry of DNA replication, induces replicative senescence in human cells. How-ever in rodent cells, replicative senescence occurs despite very long telomeres. Recent findings suggest that replicative senescence is just the tip of the iceberg of a more general process termed cellular senescence. It appears that cellular senescence is a response to potentially oncogenic in-sults, including oxidative damage. In young orgainsms, growth arrest by cell senescence sup-presses tumor development, but later in life, due to the accumulation of senescent cells which se-cret factors that can disrupt tissues during aging, cellular senescence promotes tumorigenesis. Therefore, antagonistic pleiotropy may explain, if not in whole the apparently paradoxical effects of cellular senescence, though this still remains an open question.

• 혜화의학회지
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• 제21권2호
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• pp.105-112
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• 2013

In oriental medicine, the skin of the face and the body is the mirror of the viscera and bowels. Skin aging is measured according to the elasticity and glossiness of the skin, which is perceived as a matter of fluid-humor within the realms of oriental medicine. Fluid-humor refers to normal body fluid that makes the skin moist and supple and the hair bright and glossy. If the body is lacking fluid-humor, the hair and skin will be dry and coarse. 'The improvement of fluid-humor (nutrition)' is facilitated based on the oriental physiological change theory for middle-aged women. A new study is therefore necessary to develop oriental herbal cosmetics for young women in their 20s. As yet, there has been no study on the effect of herbal cosmetics formulated for middle-aged women and used by young women in their 20s. This study aims to investigate the effect of 'the improvement of fluid-humor' for the skin of young women in their 20s within the theory of oriental medicine. This kind of study is essential for oriental skin care and the development of diverse oriental herbal cosmetics. To determine the effect of oriental herbal cosmetics on young women in their 20s based on the theory of oriental medicine, which says that a shortage of fluid-humor causes skin aging, this study has examined the skin conditions of young women in their 20s and how satisfied they are with oriental herbal cosmetics through an objective equipment-based measurement and subjective questionnaire survey.

• International Journal of Human Ecology
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• 제15권2호
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• pp.33-41
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• 2014

The bra is one of the most essential pieces of women's underwear which gives support for the breasts and holds them in position to make better outer appearance of upper body. Despite being worn by most women of all ages, brassiere manufacturers often use brassiere sizes and shapes that are close to the body measurements of women in their 20s, which raises questions whether the bras are suitable for older women's physique. Also, many lingerie markets tend to center on designs and tastes of younger women, leaving those of older women are largely ignored in the manufacturing process despite the fact that their purchasing power and market shares are expected to grow in conjunction with the aging of the global population. Against this backdrop, this study attempts to provide information about bra preferences and breast perceptions of the middle-aged and older US women over the age of 40 years to help manufacturers better understand the bra purchasing priorities and bra elements of older women and prompt them to design bras with a high level of fit and comfort that are appreciated by the population groups as a means to ultimately acquire competitive edge in the fast growing aging market. An email survey and interviews were conducted with 301 US women who live in New York City. The findings of this study suggest that there are internal and external factors such as changes in body and breast shapes with age influence the level of fitness and effectiveness of bra components, and thus the responses to the questions on bra preferences and breast perceptions varied between the researched age groups.

• 한국패션뷰티학회지
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• 제2권1호
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• pp.5-13
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• 2004

This study was analyzed on relationship of blood vessel pressure massage and skin and management method on blood vessel pressure for skin care with Yin-yang 5 factors theory, Yin-yang 5 factors theory of blood vessel pressure massage with related Korean medicine is essential for descriptions of the physiology of human body and disease. Six elements(wind, heat, fire, dryness, wetness, and cold) and seven emotions(anger, happiness, thought, worry, sadness, surprise, and fear) effected on skin care and the five viscera and the six stomach. Blood vessel pressure massage related with skin consists of the five viscera and the six stomach and is improved blood circulation and is retarded aging of skin by controls of hormone and free nerve system. Blood vessel pressure massage for skin care improved in the intestine system and blood circulation and got healthy. The blood vessel pressure massage treatment of beauty art can aid the function of bio-rhythm of a human body and make our body health by healing the problems of the five viscera organs and the six stomach. It also help circulate of the blood flow and vigor. The study expects the related researches to improve the various treatments through this treatment. The researcher encountered many problems with the lack of concerned materials and former studies but expects this study to be a study to retard aging the skin and prevent the diseases through the study of the blood vessel pressure massage.

• 한국의류산업학회지
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• 제10권3호
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• pp.335-341
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• 2008

This study aims to present the basic information on ready-made clothes production for middle-aged women by examining the clothing-related problems due to the body-shape changes of middle-aged women, and accordingly analyzing the satisfaction level with the purchasing and size of ready-made clothes among the 40-50's women. For this study, a survey was conducted to find out the satisfaction level with the purchasing and size of ready-made clothes. Among the total of 450 copies of questionnaires, 443 were collected, 400 of which were used in the analysis leaving out the rest imperfect ones. SPSS 11.0 Program was used in data analysis to get the frequency and percentage of each item. As for the preferred styles according to the age, respondents aged 45-49 preferred sweaters and trousers most, while most of middle-aged women preferred blouses and trousers most. As for the preferred styles according to occupations and body figures, most of middle-aged women preferred blouses and trousers most. The findings of this study examining the actual conditions of ready-made clothes purchase and wearing, and size satisfaction among the 40-50's women, who will be at the center of the aging populations in the Super-aged society highlight the need to correct the problems of adherence only to the prices, measures, and aesthetic aspects of fashion trends, to meet the requirements and preferences of ready-made clothes for aging women, and fulfill satisfactory functions according to the body figures in the upcoming Super-aged society.

• Journal of Yeungnam Medical Science
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• 제39권4호
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• pp.285-293
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• 2022

Background: This study was conducted to analyze the effects of low skeletal muscle mass index (SMI) and obesity on aging-related osteoarthritis (OA) in the Korean population. Methods: A total of 16,601 participants who underwent a dual-energy X-ray absorptiometry and 3,976 subjects with knee X-rays according to the modified Kellgren-Lawrence (KL) system were enrolled. Knees of ≥KL grade 2 were classified as radiologic OA. The severity of joint space narrowing (JSN) was classified by X-rays as normal, mild-to-moderate, and severe JSN in radiologic OA. The subjects were grouped as normal SMI (SMI of ≥-1 standard deviation [SD] of the mean), low SMI class I (SMI of ≥-2 SDs and <-1 SD), and low SMI class II (SMI of <-2 SDs). Obesity was defined as a body mass index (BMI) of ≥27.5 kg/m². Results: The modified KL grade and JSN severity were negatively correlated with the SMI and positively correlated with BMI and age. The SMI was negatively correlated with age. JSN severity was significantly associated with a low SMI class compared to a normal SMI, which was more prominent in low SMI class II than class I. Obesity was significantly associated with more severe JSN, only for obesity with a low SMI class. Furthermore, patients with a low SMI class, regardless of obesity, were prone to having more severe JSN. Conclusion: This study suggested that a low SMI class was associated with aging and that an age-related low SMI was more critically related to the severity of JSN in OA.

• 한국의류학회지
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• 제41권4호
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• pp.722-740
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• 2017

This study was conducted to offer basic data that can be used in a clothing industry for active senior males that are emerging as a new consumer bracket in a rapid aging age. To this end, this study conducted an analysis of 'younger' older male body types based on data from the 6th Size Korea. As a result of the body type analysis of 'younger' older males who are considered active seniors in comparison to 'middle' aged males, the former's height items became shorter compared to 'middle' aged males, but circumference items were bigger. Males aged 35-69, who are 'middle' aged males and 'younger' old males were divided into three body types in this study: Type1- small body type with protruded belly, compared to weight. Type 2- body type of slim torso with wide shoulder-back widths. Type3- big body type overall with tall height and heavy weight. According to body type distribution by age group, the middle-aged males had Type2 body type the most. The younger-old males showed type1 the most. There is a need to reflect the body types of active senior male characteristics in apparel pattern design because the current fits are not appropriate if active senior males wear clothing targeted for males aged 30-50.

• 패션비즈니스
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• 제22권2호
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• pp.27-39
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• 2018

This study analyzed the body shape of women over 70 years and classified their body shapes in order to provide basic data for the development of pants patterns that can complement the weakness of the body shape of elderly women. It were analyzed using SPSS Ver. 20.0. Five factors were extracted from the lower body: obesity and thigh thickness, lower body length, under knee thickness, ankle height, and hip sag. In type 1, the lower body was obese and the legs were thick, but the hips were not sagging. It was named 'high-hip obesity figure'. Type 2's abdomen, hip, and waist were obese, but the legs were thin and the hip were not sagging. Thus, 'bird-leg middle obesity figure' was the name. Type 3 had a long and slender lower body, but legs were thick and the hips were saggy, it was named 'strong-leg low-hip slender figure'. The elderly women showed less difference in waist, abdomen, and hip circumference. The abdominal circumference was 2-3cm more than the waist and hip circumference; hence there is a need to differentiate the shape and number of darts in the production of bottom-wear patterns for older women. In addition, the leg circumference is gradually reduced by aging compared to the size of the lower body. Therefore, it would be necessary to search for a method that can effectively design the difference between the hip circumference and the leg circumference in relation to the body shape and the aesthetics of older women.

• 복식
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• 제56권7호
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• pp.121-132
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• 2006

The feeling of self-confidence, the sense of well-being and of social acceptance that comes from the wearing clothes that is functional, appropriate, and attractive, is important to all the people, but to those with physical limitations, it is much more important. Finding well-fitting clothing can be a big challenge for them. This study focus on the cut of present available ready-to-wear garments and commercial patterns giving better fit and greater comfort and satisfaction. Subjects were limited to the people with body deformities caused by the brain injury. This can also meet the needs of silver groups in the aging society under the terms of human values and human rights. This study is based on the questionaires and interviews to identify the problems of ready-to-wear or commercial patterns, purchasing behaviors, and the demand for the functional clothes. This study focused on following objectives; 1) to discover what the problems are which confront the people with body deformity, 2) to find the problems in ready-to-wear garments or commercial patterns, 3) to provide information of pattern alteration f3r people with body deformities. A major limitation to the study is that the subjects numbers are limited and the distribution is not even. For the future study, large database with wide varieties of age and fitting test are suggested.

• 한국지역사회생활과학회지
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• 제19권1호
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• pp.145-155
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• 2008

From the menopause, women's aging progress is accelerated. Changes of lower body somatotype are accentuated in abnormal of body index and proportion. The purpose of this study is making more functional, more beautiful and more comfortable slacks for the postmenopausal women who actively participate in social activities. The results of this study are as follows: As the characteristics of this study pattern, hip circumference was replaced with maximum lower body circumference, the crotch length was defined as H/4, front crotch extension was H/16 and back crotch extension was defined as H/8. The center backline was set up with half of crotch level line. As characteristics of style, waist line is lowered 2cm at the center front, 1cm at the center back with a little bent waistband. Knee line was set up heightened 6cm from crotch level to the ancle, and widened the width of the knee and ancle, and made in semi bell bottom. 6 women who put on slacks designed from their body size evaluated that their experimental slacks were superior than ready to wear.