• 한국노년학
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• v.30 no.4
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• pp.1409-1427
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• 2010

The purpose of this study is to understand volunteer work experiences of senior citizen volunteers serving in the welfare center in K district in the aspect of an insider and to apprehend the meaning. The objects of this study are fifteen senior citizen volunteers and two social workers who do volunteer works in the welfare center, and this study utilized the qualitative study method through observations and in-depth interviews from 2009.09.02 to 2009.10.21. The data analysis is processed by the qualitative analysis program, Nvivo 2.0, and the processed data are analyzed in accordance with the grounded theories of Strauss and Corbin. As a result of reviewing data, the meanings about volunteer work experiences of senior citizens are induced as eight factors; senior citizens' identity in an old aging society, desire fulfillment through volunteer works by senior citizens, various leisure activities to help their health in mind and body, acceptance attitude about aging, mental supports from their families, finding activities suitable for each person's personality and capability, changes of perception about the handicapped, and endeavors to spend meaningful old age. Through results and discussion obtained by this study, the conclusion is as below: First, participation induction factors are identities of elderly people in aging society, acceptance attitudes toward aging and emotional support from families in the matter of senior citizens' volunteer work. Second, programs suitable for individual aptitude and capability should be implemented for activating senior citizens' volunteer work. Third, participation in senior citizens' volunteer work indicates desire satisfaction through senior citizens' volunteer work, leisure activities helping health for body and mind, and life changes such as changes of perception about handicapped people etc.

• Biomolecules & Therapeutics
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• v.23 no.6
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• pp.557-563
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• 2015

Skin aging is the most readily observable process involved in human aging. Ultraviolet B (UVB) radiation causes photo-oxidation via generation of reactive oxygen species (ROS), thereby damaging the nucleus and cytoplasm of skin cells and ultimately leading to cell death. Recent studies have shown that high levels of solar UVB irradiation induce the synthesis of matrix metalloproteinases (MMPs) in skin fibroblasts, causing photo-aging and tumor progression. The MMP family is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis and metastasis. We investigated the effect of diphlorethohydroxycarmalol (DPHC) against damage induced by UVB radiation in human skin keratinocytes. In UVB-irradiated cells, DPHC significantly reduced expression of MMP mRNA and protein, as well as activation of MMPs. Furthermore, DPHC reduced phosphorylation of ERK and JNK, which act upstream of c-Fos and c-Jun, respectively; consequently, DPHC inhibited the expression of c-Fos and c-Jun, which are key components of activator protein-1 (AP-1, up-regulator of MMPs). Additionally, DPHC abolished the DNA-binding activity of AP-1, and thereby prevented AP-1-mediated transcriptional activation. These data demonstrate that by inactivating ERK and JNK, DPHC inhibits induction of MMPs triggered by UVB radiation.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.131-134
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• 2008

The numbers of the elderly who suffer Empty Nest Syndrome have been accelerated as an aging population has increased vastly and nuclear families have been a dominating family type in modern Korean society. To make the elderly get out of this phenomenon and live actively, the scheme of converting their existing houses into shared houses was set as a hypothetical solution in this study, and finding out the responses of the elderly who owns their own houses is the purpose of the study. A small workshop panel method was used and the elderly aged 55 years upwards took part and they own a detached house that is relatively large for the elderly or the elderly couple to live alone. The workshop was consisted of 3 stages: 1. a survey 2. an interview 3. a site visit. Through this, problems that the elderly have been experiencing within their houses were looked into and the responses of the elderly on converting their houses to shared houses by introducing developed schematic plans. As a result, positive responses from the house owners were carried out based on the fact that subsidies from the government on house renovation and tenants matching programs are supported. Shared houses could provide home owners economical support with rents and help them to feel less lonely. This is one way of supporting the elderly to live and age actively in their later lives. Therefore, this idea should be established in connection with preparing aging, aged, and super-aged society.

• Journal of The Korea Institute of Healthcare Architecture
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• v.16 no.1
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• pp.55-63
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• 2010

The study was initially designed to look into the soon-to-be senior citizens' preferences for the life after retirement in aging society. Its outcomes are to be contributed to grading up the quality of housing culture through examining the expected changes of housing types in the future. The increasing number of the soon-to-be senior citizens becomes leading subjects in information, culture and consumption areas. Therefore it is significant to present a model of housing types for those citizens by analyzing their preferred residence after retirement. To complete those objectives, a set of questionnaires concerning sex, age, district, education and income of those subjects in 40's-50's, who are expected to be more than 20 percent of national population by 2030, were collected and analyzed to find out their preferences over housing types, residential welfare facilities, and co-housing. The results show that the preferences over the residential welfare facilities and co-housing for those who are able to move for themselves are low, while the preferences over single-unit houses in the suburbs within 2 hours from a city are very high. Preferences for apartments in the urban areas are high for those with high income and education. In contrast preferences for life in their hometowns are high for those whose income and education are relatively low. Most of those with some difficulties in moving for themselves want to get help with welfare facilities for the elderly people. And the preferences of those who want to receive help from assistants are different from those preferring to get help from their offsprings, which tells a need for further study of the convertible housing types according to their family members.

• Journal of Microbiology and Biotechnology
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• v.25 no.8
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• pp.1307-1314
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• 2015

Leukemia inhibitory factor (LIF) is a member of the IL-6 cytokine family, having pleiotropic actions such as maintaining stem cell pluripotency and enabling blastocyst implantation. Because the action of LIF is mediated by a ligand-receptor interaction with the LIF receptor (LIF-R), an antagonist for LIF-R has been developed to inhibit LIF-induced signaling. In this study, we present a novel method for the production and purification of an antagonist to human LIF-R (hLA). His-tagged hLA was expressed in E. coli, and simple purification methods without any endopeptidase cleavage were designed. In addition, we determined the optimal temperature conditions for enhancing the production of soluble hLA. Finally, the bioactivity of His-tagged hLA was examined using STAT3 phosphorylation and receptivity of human endometrial ECC-1 cells. Our strategy provides a rapid and efficient method to produce biologically active recombinant hLA.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.4
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• pp.46-55
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• 2012

Objectives: It is well known that genetic factors and environmental factors play major role in aging skin. In general, son and daughter take after their parents in appearance. But comparability of skin properties in Korean family has not been well estimated. So we evaluated the correlation of skin properties in Korean mother-daughter pairs. Methods: 10 couples of mother and daughter pair(n=20) participate in this study. Mothers and daughters were aged $50.6{\pm}2.459$ and $23.8{\pm}2.15$ years, respectively. Skin moisture, sebum, skin color and elasticity is measured using non-invasive method : Corneometer CM825, Sebumeter(MPA580), Mexameter MX18, Cutometer MPA580. Statistical analysis program we used is Minitab 14 Korea. Results: The Skin moisture of mother group was significantly higher than daughter group. And skin elasticity(R2) of the daughter group was significantly higher than mother group. In the results of correlation analysis between mother and daughter pairs, skin elasticity(R2) had high positive correlation(r=0.729, p=0.026). But skin moisture, sebum, melanin index, erythema index and skin elasticity(R5) did not be confirmed a significant correlation. Conclusions: Skin elasticity(R2) is the only factor that showed high positive correlation significantly in mother and daughter pairs. Mother and daughter share the genetic factors and environmental factors that influence skin aging. So, mother's aging pattern will be a good guide for anti-aging of daughters.

• Journal of Digital Convergence
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• v.17 no.7
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• pp.157-165
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• 2019

Geron-technology contributing to successful "Aging in place" increases the quality of life for the elderly and decreases the social caring cost. This study aims to identify influencing factors on pre-implementation acceptance of geron-technology for the elderly residing in a community. Data for 129 participants were analyzed. Results indicated that location, physical function, lack of technical support by family members, and the high financial cost as a 28% power were identified as the influencing factors on pre-implementation acceptance of geron-technology. Therefore, in the development of health and welfare strategy, these influencing factors should be considered in order to archive 'aging in place' for the elderly.

• Journal of Family Resource Management and Policy Review
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• v.27 no.1
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• pp.1-12
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• 2023

This study forecasts the outlook 10 years from now regarding domestic labor and caregiving by the Baby Boomer generation and the preparations needed in the context of the Fourth Industrial Revolution. The scenario-planning method was used to explore changing trends in domestic labor and caregiving, the rationale for which has been questioned by both seniors and family welfare experts. Based on the results of the survey and our researchers' opinions, it was concluded that the changing trends were caused by two factors: the probability of alterations in domestic labor and the strength of family relationships. On the basis of these conclusions, four scenarios regarding baby boomers' domestic labor and caregiving in 10 years were proposed using two axes: the "high and low probability of alterations" and the "strengthening and weakening of family relationships." The first scenario is a "preference for the self-caring form of family," which has a high probability of domestic labor alterations and weak family relationships. The second scenario is a "preference for the flexible form of family," which has a high probability of domestic labor alterations and strong family relationships. The third scenario is a "preference for the traditional form of family," which has a low probability of domestic labor alterations and strong family relationships. The fourth scenario is a "preference for the public caregiving form of family," which has a low probability of domestic labor alterations and weak family relationships. These results provide basic information about the various aspects of baby boomers' lives-including the development of various goods and services, the establishment of policies regarding seniors, and programs for successful aging-and can help equip our society to take the actions needed for a super-aged population.

• Journal of the Korean Home Economics Association
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• v.50 no.6
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• pp.99-117
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• 2012

This study aimed to measure consumer information competency, which indicates consumers' general ability to search and utilize information. The model of this study was constructed in order to identify how consumer information competency influences the efficiency and the effectiveness of external information search. The model was verified with related prior knowledge as a moderator variable in order to understand holistic consumer information search activity. The result of the study is as follows. First, the concept of consumer information competency was constructed with four sub-abilities: define, search, extract, and synthesis & use. The ability of define was the highest, as opposed to the ability of extract, which was the lowest. Second, consumer information competency was lower for women as well as for low family income. The sub-abilities of search and synthesis & use were lower for aging consumers. Third, consumer information competency has positive effects on information search efficiency and effectiveness. Moreover, the efficiency influences the effectiveness positively. Fourth, prior knowledge moderates the effect of consumer information competency to the efficiency. Only for consumers with high knowledge the efficiency has the effect of mediating between consumer information competency and the effectiveness.

• Journal of the Korean housing association
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• v.17 no.2
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• pp.151-158
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• 2006

Medical technology being developed, the increase of the aged population brings about many changes in financial standard, consciousness and lifestyle. And the increase of a nuclear family and a professional woman makes their family not to be able to support them anymore. Because aged people also don't want to rely on their family, aged people households are growing gradually. These causes make a house and a living environment of aged people to new social problems and these became elements to determine the living quality. In case of advanced nations a house considered of the physical character of aged people has been planned and they can live with various services in their houses and community that they are living without moving: But a hou! se for aged people is initial stage in Korea. And most facilities are poor and just for protection and accommodation. Although concerning a house for the aged according to revised the aged welfare law, companies are waiting to build because of problems of cognition and regulation. Therefore the plan considered of the character of the aged is being needed for the independent and comfortable living of the aged.