• 제목/요약/키워드: Aging factor

검색결과 878건 처리시간 0.022초

청심연자탕으로 호전된 뇌경색을 동반한 심방세동 환자 치험 3례 (Case Report of Chengsim Yeunja-tang (CYT) for Atrial Fibrillation with cerebral-infarction.)

  • 김정철;오성원;송창훈;이슬희;정종진;김종윤;선승호
    • 대한한방내과학회지
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    • 제27권3호
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    • pp.751-761
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    • 2006
  • Atrial fibrillation (AF) is a common arrhythmia that is a potent independent risk factor for stroke. The incidence of AF increases with age and most affected people have underlying cardiac disease. An aging society increases the incidence of AF patients. The case was designed to evaluate the improving effect of Chengsim Yeunja-tang (CYT) for atrial fibrillation (AF) with Cb-infarction patients. This patient was treated with CYT and had significant improvement in symptoms and change of EKG. -Heart rate decreased in patients with higher than normal heart rate -RV5+SV1 voltage decreased (LVH improved) -Arrhythmia remained steady. -Palpitation. chest discomfort, dyspnea, headache, dizziness diminished. Results suggest that CYT is an effective treatment for Taeumin AF patients.

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2년후에 발거가 가능했던 기관 cannula 발거곤란병 (A Successful Decannulation Case Two Years Later A Tracheostomy)

  • 이종원;김종영;김성곤;권령춘;양한모
    • 대한기관식도과학회:학술대회논문집
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    • 대한기관식도과학회 1976년도 제10차 학술대회연제 순서 및 초록
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    • pp.87.3-87
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    • 1976
  • 병례 환자 : 강○종 4세 남자, 주소 : 기관 cannula 발거시의 호흡곤란, 병력 : 래원 2년전 소아과에서 기관절개술을 받았으며, 기관절개술 1개월후에 기관 cannula 발거곤란병으로 재수술을 받았음. 경과 : 양친에 의해 cannula corking 하에서 정상기도를 통한 호흡연습을 하여 1976년 3월 16일 본 교실에서 아무런 후유증 없이 기관 cannula를 발거하여 2일후 퇴원하였음. 2년간 기관 cannula의 발거가 곤란했던 5세 남아에서 기관 cannula 발거후 아무런 지장이 없었던 1례를 경험하였기에 보고한다. 정상기도를 통한 호흡곤란이 내외과적 수단을 가하지 않고 2년후에 기관 cannula의 발거가 가능했다는 사실은 1종의 자연치료현상으로 보아야 할 것이다. 물론 high tracheostomy로 인하여 cricoid cartilage의 손상, perichondritis, granulation 및 성문하종창의 동반이 있었다. 이러한 호흡곤란이 성장에 수반되는 기관성장이나 cannula corking 하에서 정상기도를 통한 꾸준한 호흡연습이 2년후에 기관 cannula의 발거를 가능케 했다고 볼 수도 있으나 암의 자연치료현상을 면역으로 설명하는 것과 같이 이러한 병례도 면역에 의한 자연치유나 unknown factor 등을 부가하여 생각할 수도 있겠다.

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Brewing Rutin-Enriched Lager Beer with Buckwheat Malt as Adjuncts

  • Deng, Yang;Lim, Juho;Lee, Gang-Hee;Nguyen, Thi Thanh Hanh;Xiao, Yang;Piao, Meizi;Kim, Doman
    • Journal of Microbiology and Biotechnology
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    • 제29권6호
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    • pp.877-886
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    • 2019
  • Brewing with buckwheat as an ingredient has been proven to be successful in several previous studies. However, few studies have focused on the effects of buckwheat on the rutin content and antioxidant activity of beer. In order to develop a lager beer with high rutin content and desirable sensory characteristics, tartary buckwheat malt was used as a brewing adjunct. The results showed that the rutin-degrading enzyme was the key factor affecting the rutin content in the wort and beer. Compared to beer made using the common mashing method, the rutin content in the buckwheat beers produced using an improved mashing method was approximately 60 times higher. The total flavonoid contents in buckwheat beers also depended strongly on the mashing methods, ranging from 530.75 to 1,704.68 mg QE/l. The rutin-rich beers also showed better oxidative stability during forced-aging. Meanwhile, the buckwheat beers were found to be acceptable in terms of the main quality attributes, flavor, and taste.

A Brief Review of κ-Carbide in Fe-Mn-Al-C Model Alloys

  • Seol, Jae Bok
    • Applied Microscopy
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    • 제48권4호
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    • pp.117-121
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    • 2018
  • The multiple length scale analysis of previously designed Fe-Mn-Al-C based low-density model alloys reveals the difference in ordered ${\kappa}-carbide$, $(Fe,Mn)_3AlC_x$, between Fe-25Mn-16Al-5.2C (at%) alloy and Fe-3Mn-10Al-1.2C (at%) alloy. For the former alloy composition consisting of fully austenite grains, ${\kappa}-carbide$ showed majorly cuboidal and minorly pancake morphology and its chemical composition was not changed through aging for 24 h and 168 h at $600^{\circ}C$. Meanwhile, for the isothermally annealed ferritic alloy system for 1 hr at 500 and $600^{\circ}C$, the dramatic change in the chemical composition of needle-shape ${\kappa}-carbide$, $(Fe,Mn)_3(Fe,Al)C_x$, was found. Here we address that the compositional fluctuations in the vicinity of the carbides are significantly controlled by abutting phase, either austenite or ferrite. Namely, the cooperative ordering of carbon and Al is an important factor contributing to carbide formation in the high-Mn and high-Al alloyed austenitic steel, while the carbon and Mn for the low-Mn and high Al alloyed ferritic steel.

Factors Influencing Care Behavior of Certified Care Assistants for Older Adults with Dementia

  • Kim, Ji-yeon;Tak, Sunghee H
    • 노인간호학회지
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    • 제20권3호
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    • pp.185-192
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    • 2018
  • Purpose: Korea is one of the most rapidly aging countries, accompanied by an increasing number of older adults with dementia. Certified-care-assistants are the primary care workers for these older adults. This cross-sectional descriptive study compared the factors influencing care behaviors among Korean and non-Korean certified-care-assistants in Korea. Methods: Participants, 113 Korean certified-care-assistants and 71 non-Korean certified-care-assistants, completed a survey questionnaire. The questionnaire was designed to assess dementia knowledge, attitude and care behaviors toward older adults with dementia. To determine the differences in these two groups, t-test was used. A stepwise multiple regression was performed to identify factors related to care behavior. Results: Significant differences in dementia knowledge, attitude and care behavior toward older adults with dementia emerged between Korean and non-Korean certified-care-assistants. Factors influencing care behavior varied by group. Dementia knowledge and education level were the significant factors of care behaviors in Korean certified-care-assistants, whereas attitude toward older adults with dementia was the significant factor in non-Korean certified-care-assistants. Conclusion: Findings indicate that different factors influence the care behavior of two groups. These findings can be utilized to develop certified-care-assistants' training curriculum that needs to be tailored by nationality to improve the quality of care for older adults with dementia.

Ringing Frequency Extraction Method Based on EMD and FFT for Health Monitoring of Power Transistors

  • Ren, Lei;Gong, Chunying
    • Journal of Power Electronics
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    • 제19권1호
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    • pp.307-315
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    • 2019
  • Condition monitoring has been recognized as an effective and low-cost method to enhance the reliability and improve the maintainability of power electronic converters. In power electronic converters, high-frequency oscillation occurs during the switching transients of power transistors, which is known as ringing. The ringing frequency mainly depends on the values of the parasitic capacitance and stray inductance in the oscillation loop. Although circuit stray inductance is an important factor that leads to the ringing, it does not change with transistor aging. A shift in either the inside inductance or junction capacitance is an important failure precursor for power transistors. Therefore, ringing frequency can be used to monitor the health of power transistors. However, the switching actions of power transistors usually result in a dynamic behavior that can generate oscillation signals mixed with background noise, which makes it hard to directly extract the ringing frequency. A frequency extraction method based on empirical mode decomposition (EMD) and Fast Fourier transformation (FFT) is proposed in this paper. The proposed method is simple and has a high precision. Simulation results are given to verify the ringing analysis and experimental results are given to verify the effectiveness of the proposed method.

Carpomitra costata Extract Suppresses Interleukin-1β-Induced Inflammatory Response in SW1353 Human Chondrocytes through Suppressing NF-κB Signaling Pathway

  • Choi, Yung Hyun
    • 한국해양바이오학회지
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    • 제12권2호
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    • pp.99-107
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    • 2020
  • Osteoarthritis (OA) is an inflammatory degenerative joint disease that is accompanied by irreversible joint cartilage destruction. Recently, the antioxidant effects of Carpomitra costata, which is a type of brown algae, have been reported, but their effects on OA have not been investigated. In this study, the anti-osteoarthritic effect of the ethanol extract of C. costata (EECC) on SW1353 human chondrocytes was studied. Results showed that EECC significantly attenuated the interleukin-1β (IL-1β)-induced release of pro-inflammatory mediators, including prostaglandin E2 and nitric oxide (NO), as well as expressions of cyclo-oxygenase-2 and inducible NO synthase. EECC also inhibited the IL-1β-induced expressions of matrix metalloproteinase-1, -3, and -13 in SW1353 chondrocytes, which reduced their extracellular secretion. In addition, the oxidative stress induced by IL-1β was confirmed to be blocked by EECC due to the inhibition of reactive oxygen species generation. Moreover, EECC suppressed IL-1β-mediated translocation of nuclear factor-kappa B (NF-κB) from cytosol into the nucleus and the degradation of IκB-α, which indicates that EECC exhibits anti-inflammatory effects by inhibiting the NF-κB signaling pathway. These results are the first to demonstrate the anti-inflammatory activities of C. costata extracts in chondrocytes, thus suggesting that this algae extract may be used in the treatment of OA.

리튬 이차 전지의 전기화학 모델링과 전기적 실험 기반 상태 추정 (State of Health estimation based on Secondary Li-ion battery Electrochemical Modeling and Electrical experiment)

  • 김수안;박성윤;김종훈
    • 전기전자학회논문지
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    • 제24권4호
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    • pp.1098-1103
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    • 2020
  • 본 논문은 리튬 이온 이차 전지의 전기적 실험 및 전기화학적 모델링을 통한 배터리 수명 상태(SOH)의 추정 방법을 다룬다. 배터리 전기적 노화 실험을 통하여 실제 배터리 수명 상태를 확인하기 위하여 전류 적산법을 사용한다. 전기적 실험에서 도출한 내부저항 값을 사용하여 SOH를 추정하며, 전기화학 모델링에서 사이클 수의 증가에 따른 SEI Layer의 변화를 통해 SOH를 추정한다. 실제 배터리 수명 상태를 포함한 세 가지 방법의 SOH 추정 방법에 가중치를 적용하여 새로운 SOH를 도출하며, 이는 전류적산법을 사용하여 구한 실제 값과의 오차를 줄여주어 추정 성능을 높인다.

벽지노선 대체형 수요응답형교통(DRT) 노선 선정 방안에 관한 연구 - 경상남도 대중교통 열악지역을 대상으로 - (A Study on the Route Selection Method for Demand Response Transport (DRT) Replacement for Bus Services in Vulnerable Areas - Focused on Region Vulnerable to Public Transportation of GyeongSangNam-Do in Korea -)

  • 박기준;송기욱;정헌영
    • 국토계획
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    • 제54권4호
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    • pp.71-78
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    • 2019
  • Due to the rapid pace of low fertility and aging of Korea, population decline is rapidly progressing in the outskirts of the province and county. Demand for public transport is decreasing due to suburban population declines, while local government funding for maintenance of the bus system is expected to increase gradually. The government and municipalities are promoting the introduction of Demand Responsive Transport (DRT) in order to reduce the burden of financial support for buses while enhancing mobility of the residents in vulnerable areas. However, most DRTs in Korea have been operated mainly in the areas that are not provided with public transportation services. Although DRT is able to reduce the financial burden of local governments, it is not easy to be introduced because of the objection of the existing bus users. In this study, 11 out of 61 towns with poor public transportation services in Gyeongsangnam-Do were selected for the introduction of DRT to replace bus services by using village characteristics. The results of this study are expected to be used as a basis for decision making to use DRT instead of bus service for the burden of bus financing for local governments.

난소 절제 동물모델을 이용한 경옥고의 갱년기 증후군 개선 효과 (The Ameliorating Effect of Kyung-Ok-Go on Menopausal Syndrome Observed in Ovariectomized Animal Model)

  • 조경남;정서윤;배호정;류종훈
    • 생약학회지
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    • 제51권4호
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    • pp.310-316
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    • 2020
  • Kyung-Ok-Go (KOK) is a traditional prescription used for debilitating natural aging and post-illness debilitation. KOK has been used in a variety of ways because it strengthens immunity, prevents illness, and helps recovery in case of illness. In particular, recent research has revealed that KOK helps improve memory and cognition. Therefore, in this study, we investigated whether KOK was effective in improving memory decline and depression-state observed during menopause. In the present study, we employed ovariectomized mouse as an animal model for measuring menopausal syndrome. The administration of KOK for 8 weeks, the object recognition memory and working memory were improved in novel object recognition test and Y-maze test. And in the forced swimming test, the immobility time were decreased. Additionally, the expression level of mature brain derived neurotropic factor (mBDNF) was increased by KOK administration in ovariectomized mouse hippocampus. These results suggested that KOK could improve cognitive decline and depression during menopausal period, and it might be come from enhancing expression level of mBDNF in hippocampus.