• Title/Summary/Keyword: Aging factor

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Case Report of Chengsim Yeunja-tang (CYT) for Atrial Fibrillation with cerebral-infarction. (청심연자탕으로 호전된 뇌경색을 동반한 심방세동 환자 치험 3례)

  • Kim, Jung-Chul;Oh, Sung-Won;Song, Chang-Hoon;Lee, Seul-hee;Jeong, Jong-Jin;Kim, Jong-Yun;Sun, Seung-Ho
    • The Journal of Internal Korean Medicine
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    • v.27 no.3
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    • pp.751-761
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    • 2006
  • Atrial fibrillation (AF) is a common arrhythmia that is a potent independent risk factor for stroke. The incidence of AF increases with age and most affected people have underlying cardiac disease. An aging society increases the incidence of AF patients. The case was designed to evaluate the improving effect of Chengsim Yeunja-tang (CYT) for atrial fibrillation (AF) with Cb-infarction patients. This patient was treated with CYT and had significant improvement in symptoms and change of EKG. -Heart rate decreased in patients with higher than normal heart rate -RV5+SV1 voltage decreased (LVH improved) -Arrhythmia remained steady. -Palpitation. chest discomfort, dyspnea, headache, dizziness diminished. Results suggest that CYT is an effective treatment for Taeumin AF patients.

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A Successful Decannulation Case Two Years Later A Tracheostomy (2년후에 발거가 가능했던 기관 cannula 발거곤란병)

  • 이종원;김종영;김성곤;권령춘;양한모
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1976.06a
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    • pp.87.3-87
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    • 1976
  • The authors experienced a case of a difficult decannulation in a 4 years old boy, in which. case decannulation was possible 2 years later a tracheostomy. Some immunoglogical phenomena could be considered in this case as though cancer can remiss spontaneously. Such complications of tracheostomy as subglottic edema and perichondritis could become relatively less troublesome to breathing during his aging process. And another reason for the easy decannulation is considered as the patient could be accustomed to breathing through natural air pathway by continual cannula corking training.

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Brewing Rutin-Enriched Lager Beer with Buckwheat Malt as Adjuncts

  • Deng, Yang;Lim, Juho;Lee, Gang-Hee;Nguyen, Thi Thanh Hanh;Xiao, Yang;Piao, Meizi;Kim, Doman
    • Journal of Microbiology and Biotechnology
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    • v.29 no.6
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    • pp.877-886
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    • 2019
  • Brewing with buckwheat as an ingredient has been proven to be successful in several previous studies. However, few studies have focused on the effects of buckwheat on the rutin content and antioxidant activity of beer. In order to develop a lager beer with high rutin content and desirable sensory characteristics, tartary buckwheat malt was used as a brewing adjunct. The results showed that the rutin-degrading enzyme was the key factor affecting the rutin content in the wort and beer. Compared to beer made using the common mashing method, the rutin content in the buckwheat beers produced using an improved mashing method was approximately 60 times higher. The total flavonoid contents in buckwheat beers also depended strongly on the mashing methods, ranging from 530.75 to 1,704.68 mg QE/l. The rutin-rich beers also showed better oxidative stability during forced-aging. Meanwhile, the buckwheat beers were found to be acceptable in terms of the main quality attributes, flavor, and taste.

A Brief Review of κ-Carbide in Fe-Mn-Al-C Model Alloys

  • Seol, Jae Bok
    • Applied Microscopy
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    • v.48 no.4
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    • pp.117-121
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    • 2018
  • The multiple length scale analysis of previously designed Fe-Mn-Al-C based low-density model alloys reveals the difference in ordered ${\kappa}-carbide$, $(Fe,Mn)_3AlC_x$, between Fe-25Mn-16Al-5.2C (at%) alloy and Fe-3Mn-10Al-1.2C (at%) alloy. For the former alloy composition consisting of fully austenite grains, ${\kappa}-carbide$ showed majorly cuboidal and minorly pancake morphology and its chemical composition was not changed through aging for 24 h and 168 h at $600^{\circ}C$. Meanwhile, for the isothermally annealed ferritic alloy system for 1 hr at 500 and $600^{\circ}C$, the dramatic change in the chemical composition of needle-shape ${\kappa}-carbide$, $(Fe,Mn)_3(Fe,Al)C_x$, was found. Here we address that the compositional fluctuations in the vicinity of the carbides are significantly controlled by abutting phase, either austenite or ferrite. Namely, the cooperative ordering of carbon and Al is an important factor contributing to carbide formation in the high-Mn and high-Al alloyed austenitic steel, while the carbon and Mn for the low-Mn and high Al alloyed ferritic steel.

Factors Influencing Care Behavior of Certified Care Assistants for Older Adults with Dementia

  • Kim, Ji-yeon;Tak, Sunghee H
    • Journal of Korean Gerontological Nursing
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    • v.20 no.3
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    • pp.185-192
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    • 2018
  • Purpose: Korea is one of the most rapidly aging countries, accompanied by an increasing number of older adults with dementia. Certified-care-assistants are the primary care workers for these older adults. This cross-sectional descriptive study compared the factors influencing care behaviors among Korean and non-Korean certified-care-assistants in Korea. Methods: Participants, 113 Korean certified-care-assistants and 71 non-Korean certified-care-assistants, completed a survey questionnaire. The questionnaire was designed to assess dementia knowledge, attitude and care behaviors toward older adults with dementia. To determine the differences in these two groups, t-test was used. A stepwise multiple regression was performed to identify factors related to care behavior. Results: Significant differences in dementia knowledge, attitude and care behavior toward older adults with dementia emerged between Korean and non-Korean certified-care-assistants. Factors influencing care behavior varied by group. Dementia knowledge and education level were the significant factors of care behaviors in Korean certified-care-assistants, whereas attitude toward older adults with dementia was the significant factor in non-Korean certified-care-assistants. Conclusion: Findings indicate that different factors influence the care behavior of two groups. These findings can be utilized to develop certified-care-assistants' training curriculum that needs to be tailored by nationality to improve the quality of care for older adults with dementia.

Ringing Frequency Extraction Method Based on EMD and FFT for Health Monitoring of Power Transistors

  • Ren, Lei;Gong, Chunying
    • Journal of Power Electronics
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    • v.19 no.1
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    • pp.307-315
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    • 2019
  • Condition monitoring has been recognized as an effective and low-cost method to enhance the reliability and improve the maintainability of power electronic converters. In power electronic converters, high-frequency oscillation occurs during the switching transients of power transistors, which is known as ringing. The ringing frequency mainly depends on the values of the parasitic capacitance and stray inductance in the oscillation loop. Although circuit stray inductance is an important factor that leads to the ringing, it does not change with transistor aging. A shift in either the inside inductance or junction capacitance is an important failure precursor for power transistors. Therefore, ringing frequency can be used to monitor the health of power transistors. However, the switching actions of power transistors usually result in a dynamic behavior that can generate oscillation signals mixed with background noise, which makes it hard to directly extract the ringing frequency. A frequency extraction method based on empirical mode decomposition (EMD) and Fast Fourier transformation (FFT) is proposed in this paper. The proposed method is simple and has a high precision. Simulation results are given to verify the ringing analysis and experimental results are given to verify the effectiveness of the proposed method.

Carpomitra costata Extract Suppresses Interleukin-1β-Induced Inflammatory Response in SW1353 Human Chondrocytes through Suppressing NF-κB Signaling Pathway

  • Choi, Yung Hyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.12 no.2
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    • pp.99-107
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    • 2020
  • Osteoarthritis (OA) is an inflammatory degenerative joint disease that is accompanied by irreversible joint cartilage destruction. Recently, the antioxidant effects of Carpomitra costata, which is a type of brown algae, have been reported, but their effects on OA have not been investigated. In this study, the anti-osteoarthritic effect of the ethanol extract of C. costata (EECC) on SW1353 human chondrocytes was studied. Results showed that EECC significantly attenuated the interleukin-1β (IL-1β)-induced release of pro-inflammatory mediators, including prostaglandin E2 and nitric oxide (NO), as well as expressions of cyclo-oxygenase-2 and inducible NO synthase. EECC also inhibited the IL-1β-induced expressions of matrix metalloproteinase-1, -3, and -13 in SW1353 chondrocytes, which reduced their extracellular secretion. In addition, the oxidative stress induced by IL-1β was confirmed to be blocked by EECC due to the inhibition of reactive oxygen species generation. Moreover, EECC suppressed IL-1β-mediated translocation of nuclear factor-kappa B (NF-κB) from cytosol into the nucleus and the degradation of IκB-α, which indicates that EECC exhibits anti-inflammatory effects by inhibiting the NF-κB signaling pathway. These results are the first to demonstrate the anti-inflammatory activities of C. costata extracts in chondrocytes, thus suggesting that this algae extract may be used in the treatment of OA.

State of Health estimation based on Secondary Li-ion battery Electrochemical Modeling and Electrical experiment (리튬 이차 전지의 전기화학 모델링과 전기적 실험 기반 상태 추정)

  • Kim, Su-An;Park, Seong-Yun;Kim, Jong-hoon
    • Journal of IKEEE
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    • v.24 no.4
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    • pp.1098-1103
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    • 2020
  • This paper deals with a method for estimating the battery state-of-health(SOH) through electrical experiments and electrochemical modeling of lithium-ion secondary battery. In order to confirm the actual battery SOH through the battery electrical aging experiment, the current integration method was used. The SOH is estimated using the internal resistance value derived from the electrical experiment. Also, in electrochemical modeling, the SOH is estimated through the change of the SEI layer with the increase of the number of cycles. The new SOH is derived by applying weighting factor to the three methods of estimating SOH, including the actual battery SOH.

A Study on the Route Selection Method for Demand Response Transport (DRT) Replacement for Bus Services in Vulnerable Areas - Focused on Region Vulnerable to Public Transportation of GyeongSangNam-Do in Korea - (벽지노선 대체형 수요응답형교통(DRT) 노선 선정 방안에 관한 연구 - 경상남도 대중교통 열악지역을 대상으로 -)

  • Park, Ki-Jun;Song, Ki-Wook;Jung, Hun-Young
    • Journal of Korea Planning Association
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    • v.54 no.4
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    • pp.71-78
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    • 2019
  • Due to the rapid pace of low fertility and aging of Korea, population decline is rapidly progressing in the outskirts of the province and county. Demand for public transport is decreasing due to suburban population declines, while local government funding for maintenance of the bus system is expected to increase gradually. The government and municipalities are promoting the introduction of Demand Responsive Transport (DRT) in order to reduce the burden of financial support for buses while enhancing mobility of the residents in vulnerable areas. However, most DRTs in Korea have been operated mainly in the areas that are not provided with public transportation services. Although DRT is able to reduce the financial burden of local governments, it is not easy to be introduced because of the objection of the existing bus users. In this study, 11 out of 61 towns with poor public transportation services in Gyeongsangnam-Do were selected for the introduction of DRT to replace bus services by using village characteristics. The results of this study are expected to be used as a basis for decision making to use DRT instead of bus service for the burden of bus financing for local governments.

The Ameliorating Effect of Kyung-Ok-Go on Menopausal Syndrome Observed in Ovariectomized Animal Model (난소 절제 동물모델을 이용한 경옥고의 갱년기 증후군 개선 효과)

  • Cho, Kyungnam;Jung, Seo Yun;Bae, Ho Jung;Ryu, Jong Hoon
    • Korean Journal of Pharmacognosy
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    • v.51 no.4
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    • pp.310-316
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    • 2020
  • Kyung-Ok-Go (KOK) is a traditional prescription used for debilitating natural aging and post-illness debilitation. KOK has been used in a variety of ways because it strengthens immunity, prevents illness, and helps recovery in case of illness. In particular, recent research has revealed that KOK helps improve memory and cognition. Therefore, in this study, we investigated whether KOK was effective in improving memory decline and depression-state observed during menopause. In the present study, we employed ovariectomized mouse as an animal model for measuring menopausal syndrome. The administration of KOK for 8 weeks, the object recognition memory and working memory were improved in novel object recognition test and Y-maze test. And in the forced swimming test, the immobility time were decreased. Additionally, the expression level of mature brain derived neurotropic factor (mBDNF) was increased by KOK administration in ovariectomized mouse hippocampus. These results suggested that KOK could improve cognitive decline and depression during menopausal period, and it might be come from enhancing expression level of mBDNF in hippocampus.