• 제목/요약/키워드: Aging Index

검색결과 443건 처리시간 0.032초

Panax ginseng Improves Senile Testicular Function in Rats

  • Hwang, Seock-Yeon;Sohn, Sang-Hyun;Wee, Jae-Joon;Yang, Jin-Bae;Kyung, Jong-Soo;Kwak, Yi-Seong;Kim, Sung-Won;Kim, Si-Kwan
    • Journal of Ginseng Research
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    • 제34권4호
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    • pp.327-335
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    • 2010
  • We reported previously that the administration of Korean red ginseng water extract (KRG-WE) protected the guinea pig testis against damage induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (a potent endocrine disruptor). We also found that crude saponin from ginseng was the active ingredient responsible for this protection. Here, we examined the biological role of KRG-WE in an animal model of age-induced dysfunction of spermatogenesis. Twenty-four male Sprague-Dawley (six 2-month-old and eighteen 12-month-old) rats were used. The young and old control groups received only vehicle. The ginseng saponin (GS)- and KRG-WE-treated groups received GS (40 mg/kg body weight/day) and KRG-WE (200 mg/kg body weight/day), respectively, for 4 months. The number of cells, Sertoli cell index, Johnsen's score, and sex hormone levels decreased significantly with age. However, the administration of KRG-WE and GS markedly improved the number of germ cells, seminiferous tubular size, and Johnsen's score in the old rats. Ginseng produced a distinct testicular histological improvement in old rats. KRG-WE and GS elevated testosterone levels, while attenuating the aberrant increase in follicle stimulating hormone and luteinizing hormone levels. Sperm kinematics evaluated by a computer-assisted sperm analyzer demonstrated improvement in the percentage of motile sperm, progressive sperm motility, and curvilinear velocity associated with sperm quality, supporting the beneficial role of red ginseng in senile spermatogenesis. Overall, the total water extract had a more potent effect than the corresponding saponin fraction. In conclusion, Korean red ginseng rejuvenated age-induced testicular dysfunction. Additionally, the total water extract was more potent than the corresponding saponin fraction.

사회복지적 관점에서 본 한국의 적정인구 (Optimum Population of Korea from the Perspective of Social Welfare)

  • 김승권
    • 한국인구학
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    • 제29권1호
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    • pp.241-268
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    • 2006
  • 본 연구는 출산율이 세계 최저수준으로 낮아진 한국사회의 적정인구를 사회복지적 관점에서 논의한다. 이는 인구규모의 급격한 감소와 인구구조외 불균형이 예측되어 결과적으로 국가발전에 부정적인 영향을 줄 것으로 전망되기 때문이다. 사회복지적 측면에서의 적정인구는 1인당 복지수준 또는 사회전체의 복지수준, 곧 사회적 후생(social welfare)의 크기 또는 복지성장률이 극대화되는 지점이다. 적정 인구구조는 전체인구대비 노인인구 약 $15{\sim}17%$, 생산인구 약 $64{\sim}69%$, 그리고 고령화지수 약 $72{\sim}104$ 수준이다. 또한 현재의 인구규모 및 인구구조를 감안한 한국의 적정 인구규모는 약 $4,850{\sim}4,950$만 명인 것으로 나타났다. 따라서 저출산의 원인제거로 출산율을 회복하여야 함과 동시에 외국인력을 유입할 수 있는 준비를 갖추어야 할 것이다. 아울러 아동들이 좋은 환경에서 성장할 수 있도록 노력하고 여성과 노인이 노동시장에 참여할 수 있는 조건을 제공하여야 할 필요가 있다.

항노화 화장품 원료로서의 N-Acetyl-D-glucosamine에 관한 연구 (Study on the N-Acetyl-D-glucosamine as the Anti-aging Cosmetic Ingredients)

  • 표영희;김영은;문지선
    • 한국응용과학기술학회지
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    • 제33권4호
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    • pp.706-716
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    • 2016
  • 본 연구에서는 게나 새우의 껍데기에서 추출된 키틴을 탈아세틸화 하여 얻은 NAG를 화장품 원료로서 적용하고자 하였다. NAG와 GLC를 비교하기 위하여 피부세포에 대한 세포독성, 항염증, 멜라닌 생합성 억제능에 미치는 영향을 확인하고, 피부에 적용하였을 때 멜라닌과 홍반변화의 효과를 측정하였다. 연구 결과 Raw 264.7세포와 B16F10세포에 대해 유의한 세포독성을 나타나지 않았으며, Raw 264.7세포에서 LPS에 의해 유도된 NO 생성 항염증 저해효과는 미비 하였고, NAG는 B16F10세포에 ${\alpha}$-MSH로 멜라닌 생성을 유도한 후 멜라닌 생합성 억제능을 측정한 결과 멜라닌의 생성 증가를 농도 의존적으로 억제되는 것을 확인하였다. 이와 같은 결과로 NAG가 함유된 크림을 만들어 피부에 적용하였을 때 멜라닌 지수, 홍반지수의 감소가 통계적으로 유의미한 변화를 보여 NAG 함유 화장품이 피부미백개선을 위한 기능성화장품으로 활용 가능성을 확인할 수 있었다.

패널자료를 이용한 중국 수산물소비지출에 영향을 미치는 요인에 관한 연구 (Empirical Analysis on the Factors Affecting the Consumption of Aquatic Products in China Using Panel Data)

  • 임설매;김기수
    • 수산경영론집
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    • 제44권2호
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    • pp.19-33
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    • 2013
  • China is the world's largest producer of aquatic products and its fishery sector is comprised primarily of aquaculture facilities, both fresh and seawater, and a much smaller wild catch component. The expansion of the aquaculture sector continues to boost China's aquatic output. The increase is attributable to several factors. Among them rapidly growing domestic demand is no doubt one of the most important reasons. Rapid economic growth and rising disposable income are influencing domestic consumption and the economic recovery of major import markets is further stimulating consumption of China's aquatic products. This paper tries to examine the status, trend and reasons of consumption of aquatic products in China. Based on the analysis on the consumption of aquatic products and its change, this paper utilizes panel regression model to estimate the affecting factors of aquatic products consumption in China. By using panel data between 1997 and 2010, the results indicate that income, urbanization, aging and dummy variable have positive effects and fish price index has negative effect on China's aquatic products consumption as predicted. However, effects of meat consumption and education on fishery consumption are totally opposite with our predictions. In other words, it turns out that meat consumption has positive effect on fish consumption while education turns out to have negative effect. Finally the member of household does not show any significant effect on consumption of aquatic products in China.

생산성을 고려한 치과의사의 공급 추계와 적정성 (Estimation and adequacy of dentist supply through the dental care productivity)

  • 손세호;조현재;김현덕
    • 대한치과의사협회지
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    • 제58권2호
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    • pp.68-82
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    • 2020
  • Running title: Adequacy of dentist supply Objectives: The proper provision of dentists is very important for delivering the dental care that people need. The purpose of this study is to evaluate the adequacy of dentist supply and to predict the proper supply of dentists in Korea for the next 10 years. Methods and materials: Using the data from 2004 to 2017 in the Statictics Korea, the dental needs were measured as days of admission and the annual total dental care hours in 2020, 2023, 2026 and 2030 were predticted using regression analysis. The dental care productivity (average in-office hours) of dentists was analyzed using regression analysis including age, gender, education level and region as a confounder. The annual care hours were predicted according to seven scenarios based on the percentage of women among dentists, post-dentist education levels, the percentage of dentists in the metropolitan area, aging and retirement age. Results: The needed dentist based on the data in the Statictics Korea will be 27, 288 ~ 27, 311 in 2020, 28,104 ~ 28,1785 in 2023, 28,977 ~ 29,124 in 2026, and 30,174 ~ 30,413 in 2030. On the other hand, the number of dentists in Korea will be 26,945 in 2020, 28,813 in 2023, 30,682 in 2026 and 33,173 in 2030. The adequacy index of dentist supply will be -0.01 in 2020 to +0.10 in 2030. Conclusions: Our data showed that dentists will be adequately supplied in Korea for the next 10 years. Overall, the ratio between dentist versus 1,000 Koreans will be increased from 0.5 in 2019 to 0.7 in 2020, which will meet the mean of OECD countries.

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노인의 사회적 환경에 대한 연구 (A Study on the Social Environment of Elderly)

  • 김희정
    • 대한지역사회작업치료학회지
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    • 제5권1호
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    • pp.35-43
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    • 2015
  • 목적 : 본 연구는 노인들의 사회적 환경을 알아보고 한국의 노인생활 실태와 노인정책의 효율성을 위한 기초자료를 제시하고자 하였다. 연구방법 : 본 연구는 통계청과 국민연금공단 및 보건복지부의 자료를 참고하였고 2014년 6월 일부지역 노인을 대상으로 우울증과 죽음불안을 설문조사하여 통계분석하였다. 결과 : 첫째, 저학력이 많고 부부가구가 가장 많으며 연간소득은 경제인구의 평균수준이었다. 둘째, 매년 의료비는 노인인구 증가에 비례하여 늘어나고 있다. 셋째, 노인의 우울 요인은 미래와 자신에 대한 부정적 생각으로 인한 우울감이 가장 높았다. 넷째, 노인의 죽음 불안 수준은 자신의 죽음 불안과 자신의 죽음과정의 불안이 중간이상의 수준으로 나타났고 전체적인 죽음 불안 수준도 중간 이상으로 나타났다. 결론 : 작업치료 등 다양한 전문영역에서 입증된 사회참여 프로그램과 가족지원 프로그램을 정부차원에서 정책적으로 시행하여 노인들의 여명수명의 삶의 질 향상과 신체적, 정신적, 사회적 건강의 도모가 필요하다.

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자동차부품 제조업 근로자의 작업능력과 직무스트레스에 대한 연구 (A Study on the Work Ability and the Job Stress of the Workers in Manufacturing Industry of Automobile Parts)

  • 목연수;이동원;장성록
    • 한국안전학회지
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    • 제28권3호
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    • pp.100-106
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    • 2013
  • According to the Statistics Korea, in 2011, people over the age of 65 years old accounted for 11.8% of Korea's population. This number is expected to rise to 15.0% by 2019, making Korea an "aged society". As age increases, physical ability degrades to the point that the workload must be adjusted limitations. However, workloads are given regardless of workers' ages or abilities. In addition, a decline in work efficiency due to aging also increases the risk of work-related injuries. Furthermore, the cases of stress related diseases along with musculoskeletal disorders(MSDs) rise as main factors of industrial disasters and excessive job stress gives negative influence not only on mental health but also on physical health so that job stress becomes a hot issue as a main cause of work ability falloff and turnover. The purpose of this research is to examine how the sociodemographic characteristics, MSDs symptoms and musculoskeletal workload of workers in the manufacturing industry of automobile parts influence work ability and job stress. As a result of the research, job ability showed significant differences statistically according to age, working year, sex, marital status and musculoskeletal workload and job stress showed significant differences statistically according to age, working year, marital status and musculoskeletal workload. In addition, it showed that as the worker's job ability decreases, job stress increases.

Total energy intake according to the level of skeletal muscle mass in Korean adults aged 30 years and older: an analysis of the Korean National Health and Nutrition Examination Surveys (KNHANES) 2008-2011

  • Jang, Bo Young;Bu, So Young
    • Nutrition Research and Practice
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    • 제12권3호
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    • pp.222-232
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    • 2018
  • BACKGROUND/OBJECTIVES: Since gain or loss of skeletal muscle mass is a gradual event and occurs due to a combination of lifestyle factors, assessment of dietary factors related to skeletal muscle is complicated. The aim of this study was to investigate the changes in total energy intake according to the level of skeletal muscle mass. SUBJECTS/METHODS: A total of 8,165 subjects ${\geq}30years$ of age from the Korean National Health and Nutrition Examination Surveys (KNHANES) 2008-2011 were included in the analysis, and multivariate-adjusted regression analyses were performed to analyze the association of the quartiles of sarcopenia index (SI) with energy intake of the study population after adjusting for age and metabolic parameters. RESULTS: The increase in SI quartile was in proportion to the gradual decrease in systemic lipids and the anthropometric measurement of fat accumulation (P < 0.001). Subjects in higher SI quartiles tended to consume more total energy and energy-producing nutrients than those in lower quartiles (P < 0.001). After age, body weight, alcohol consumption, and metabolic parameters were adjusted in the analysis, total energy intake gradually increased according to the increase in SI quartile, and the association between total energy intake and SI was more pronounced in men. However, the risk (odd ratio) of having a low SI was not affected by any single macronutrient intake. CONCLUSION: In this study, total energy intake was positively associated with SI and relative skeletal mass in both men and women. However, no significant association or a weak association was observed between any single macronutrient intake and skeletal muscle mass. The data indicated that acquiring more energy intake within the normal range of energy consumption may help to maintain skeletal muscle mass.

노인의 체성분 및 지방대사와 골밀도의 상관관계 (Correlation Between Body Composition, Lipid Metabolic Indicator and Bone Mineral Density in Old Patients)

  • 양재선;한명금;정상필;강정란;송용선;김정환
    • 대한한의정보학회지
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    • 제11권2호
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    • pp.32-39
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    • 2005
  • Objectives To observe relationship between BMD(BMD; bone mineral density) and lipid metabolic indicator which consists of cholesterol, HDL(HDL; high density lipoprotein), Trigliceride which influenced by BMI(BMI; body mass index), BFR(body fat rate) indirectly and directly in both ways. Methods Among 120 old patients aging above 65 who admitted to Dep. of Oriental Rehabilitation, Jeon-Ju Oriental Medical Hospital, Won Kwang University in order to prevent demetia and CVA from Mar. 2004 to May 2005 correlationship between BMI, BFR, BMD etc. and lipid metabolic indicator was statistically analysed. Results BMD of male patient was higher than that of female patients and body weight, height, BFR, BMI was significantly related to BMD as well. Relationship between Total Cholesterol, HDL, Triglyceride and BMD was not significant. Conclusions From the above results, Relationship between Total Cholesterol, HDL, Triglyceride and BMD was not significant.

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농작물 버팀 지지용 대 및 결속 장치 (Agricultural support and solidarity devices development)

  • 한승철;김진호;이만기;이승진
    • 한국산학기술학회논문지
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    • 제15권10호
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    • pp.5945-5949
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    • 2014
  • 농촌의 고령화로 인한 일손이 감소되고 있다. 반면 노인들의 일은 늘어나고 있다. 또한 농부들은 대량생산을 목표로 하는 사람들이 늘어나고 있다. 그리고 일 효율의 문제에 있어서도 보완하기 위해 농작물을 보호하는 지지대와 집게에 대한 연구를 하려고 한다. 지지대의 강도는 바람의 세기보다 강하여 파손의 우려는 없지만 집게가 식물을 잡을 만큼의 힘을 가지고 있지 않아서 형상설계 문제로 접근 하였다. 실제 지지대와 집게에 걸리는 하중을 구하고 시뮬레이션 값과 비교하여 시뮬레이션의 정확도를 확인한다. 시뮬레이션의 신뢰성을 토대로 더 큰 힘을 버틸 수 있는 모델과 크기를 선택한다. 본 논문의 연구결과를 통해 0.1N에서 0.6N의 작용력이 작용하여도 1.29N의 작용력까지 버틸 수 있는 농작물 지지대를 설계하여 농작물 고정용 집게에 걸어 고정하게 됨으로 작업시간의 단축과 작물의 생육과 작물의 재해를 방지 및 예방, 도움이 될 것이라 판단된다.