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http://dx.doi.org/10.12925/jkocs.2016.33.4.706

Study on the N-Acetyl-D-glucosamine as the Anti-aging Cosmetic Ingredients  

Pyo, Young-hee (Department of Beautydesign, Osan University)
Kim, Young-eun (Department of Beauty, Seoul Hoseo Technical College)
Moon, Ji-sun (Department of Beauty Health, Jungwon University)
Publication Information
Journal of the Korean Applied Science and Technology / v.33, no.4, 2016 , pp. 706-716 More about this Journal
Abstract
In this study we applied the NAG obtained by the deacetylation of chitin extracted from the shells of crabs and shrimp as cosmetic ingredient. In order to compare NAG with GLC we identified the influence of cytotoxicity, anti-inflammatory, melanin biosynthesis formation inhibition on skin cell, and we measured the effects of the change of melanin and red spots. The results show that there was not any attentive cytotoxicity on the Raw 264.7 cell and B16F10 cell, and NO formation anti-inflammatory hindrance effect induced from Raw 264.7 by LPS was slight, and NAG suppressed the increase of melanin generation concentration-dependently after we induced the melanin generation with ${\alpha}$-MSH on B16F10 and measured the melanin biosynthesis inhibition. From this result, we identified the applicability of the cosmetics containing NAG as functional cosmetic for enhancing skin-lightening because when cream containing NAG was applied to skin the index of melanin red spots showed statistically meaningful changes.
Keywords
Functional cosmetics; Melanin; Skin whitening; Glucosamine; Skin;
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Times Cited By KSCI : 2  (Citation Analysis)
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