• Title/Summary/Keyword: Aging Factor

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Predictors of Successful Aging in Korean Older Women Based on Successful Aging Theory (SAT) (Successful Aging Theory (SAT)에 근거한 여성노인의 성공적 노화 예측요인)

  • Kim, Eun-Joo;Kim, Young-Hee
    • Women's Health Nursing
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    • v.17 no.4
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    • pp.378-387
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    • 2011
  • Purpose: The purpose of this study was to explore predictors of successful aging in older Korean women based on a recent mid-range nursing theory, the Successful Aging Theory (SAT). Methods: This study utilized a descriptive correlational design. The convenience sample was composed of 174 older women living in the community. Successful aging was measured using the Successful Aging Inventory (SAI). Transcendence was measured using the Self-transcendence Scale (STS). Adaptation was measured using the Coping behavior scale. Stepwise multiple regression was used to identify significant predictors of successful aging. Results: Transcendence, adaptation, and religion were shown to be predictive of successful aging. This regression model explained 56% of the variance in successful aging. The factor with the highest influence was transcendence which explained 52% of the variance. Conclusion: Gerotranscendence-promoting interventions can be an important consideration in caring for older Korean women. Adaptation and spirituality should be included in a holistic aging care.

A Study on the Aging Anxiety of the Elderly (일 지역 노인의 노화불안에 대한 연구)

  • Kim, Soon-Yi
    • The Journal of Korean Academic Society of Nursing Education
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    • v.11 no.1
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    • pp.7-15
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    • 2005
  • Purpose: The purpose of this study were to 1) degree of the aging anxiety 2) to identify predictors influencing aging anxiety of the elderly. Method: Data were collected from 179 elders & utilizing questionnaires developed by Watkins, Coates, and Ferroni(1998). Data were analyzed using SPSS/Win 10.0 program and descriptive statistics t-test ANOVA were adopted as necessary. Result: Degree of the aging anxiety were 33-60scores, mean 49.96 scores. There were significant differeence in aging anxiety scores according to relegion, and disease. conclusion : The result of this study show the aging anxiety in a improtant factor in explaining psychological health, and development of adequate intervention for the elderly population to decrease the aging anxiety.

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The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster

  • Altintas, Ozlem;Park, Sangsoon;Lee, Seung-Jae V.
    • BMB Reports
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    • v.49 no.2
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    • pp.81-92
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    • 2016
  • Insulin/insulin-like growth factor (IGF)-1 signaling (IIS) pathway regulates aging in many organisms, ranging from simple invertebrates to mammals, including humans. Many seminal discoveries regarding the roles of IIS in aging and longevity have been made by using the roundworm Caenorhabditis elegans and the fruit fly Drosophila melanogaster. In this review, we describe the mechanisms by which various IIS components regulate aging in C. elegans and D. melanogaster. We also cover systemic and tissue-specific effects of the IIS components on the regulation of lifespan. We further discuss IIS-mediated physiological processes other than aging and their effects on human disease models focusing on C. elegans studies. As both C. elegans and D. melanogaster have been essential for key findings regarding the effects of IIS on organismal aging in general, these invertebrate models will continue to serve as workhorses to help our understanding of mammalian aging.

AC Breakdown Characteristics for 22.9kV CV Power Cable Before and After Cyclic Aging for 14days (22.9kV CV 전력케이블의 14주기 고온 열화에 대한 교류파괴특성)

  • 윤대혁;김위영;박민호;박태곤
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.601-604
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    • 2001
  • 22.9 kV CV power cable is very important factor of underground distribution power line. Cyclic aging for 14days is performed to remove a large amount of the volatiles found in freshly manufactured cable. In this paper, we examined AC breakdown characteristics of CV power cable before and after cyclic aging for 14days. As the result, even if there were some exceptions, the AC breakdown voltage before aging was lower than that after aging, but most of the results were that the AC breakdown voltage after aging was lower than that before aging.

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Aging and Gasroenterrogi Changes (노화에 따른 위장관 기능의 변화)

  • 조우균
    • The Korean Journal of Food And Nutrition
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    • v.6 no.3
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    • pp.219-230
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    • 1993
  • This research aims to study the changes In gastrointestinal function attributed to aging In human. The thresholds for recognition and detection of flavors became elevated and salivary gland acinar cells decreased in the old age. But most esophageal function remained relatively Intact. Although gastric emptying time has been slowed with aging, the total intestinal transit time did not differ. Atropic gastritis due to H. pylori in old man decreased secretion of acid and Intrinsic factor and absorbability of calcium and iron. Pancreatic secretion is droned in older persons. Prevalence of gallstones rised with age. Liver size and portal blood flow decreased significantly with age. Mucosal surface area has been reported to be slightly diminished in the aging man. Glucose transporters decreased and Insulin tolerance Increased. Absorption of aromatic amino acid is diminished with age. Dietary protein In that aging human increased fecal nitrogen excretion. Vitamin A tolerance increased. Vitamin D receptor concentration decreased and resistance to 1,25-(OH)2D3 action increased. Permeability of aging small Intestine Increased. Zinc balance dirt not differ Copper absorption appeared not to be significantly affected by age. Neurotensin secretion decreased thus slowed colonic peristaltic movements and Intestinal mucosal growth.

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Effect of Pre-Aging Conditions on Bake-Hardening Response of Al-0.4 wt%Mg-1.2 wt%Si-0.1 wt%Mn Alloy Sheets

  • Lee, Kwang-jin;Woo, Kee-do
    • Korean Journal of Metals and Materials
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    • v.49 no.6
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    • pp.448-453
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    • 2011
  • Pre-aging heat treatment after solution heat treatment (SHT) of Al-0.4 wt%Mg-1.2 wt%Si-0.1 wt%Mn alloy sheets for auto-bodies was carried out to investigate the effect of pre-aging and its conditions on the bake-hardening response. Mechanical properties were evaluated by a tensile and Vickers hardness test. Microstructural observation was also performed using a transmission electron microscope (TEM). It was revealed that pre-aging treatments play a great role in the bake-hardening response. In addition, it was found that the sphere-shaped nanosized clusters that can directly transit to the needle-shaped ${\beta}$" phase during the paint-bake process, not being dissolved into the matrix, are formed at 343 K. The result, reveals that the dominant factor of the bake-hardening response is the pre-aging temperature rather than the pre-aging time.

Arrhenius Kinetic Constants Analysis of BKNO3 under Accelerated Aging (가속노화에 따른 BKNO3의 아레니우스 동역학 상수 분석)

  • Jang, Seung-gyo;Kim, Jun-hyung;Ryu, Byung-tae;Hwang, Jung-min
    • Journal of the Korean Society of Propulsion Engineers
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    • v.20 no.4
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    • pp.34-39
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    • 2016
  • Arrhenius kinetic constants, the activation energy and the pre-exponential factor, of energetic material $BKNO_3$ are estimated using Differential Scanning Calorimetry (DSC). Different from the conventional way, the activation energy was estimated more precisely through DSC aging trial, and the consumed fraction by heat was calculated by comparing the integration of heat flow. We suggested the condition of accelerated aging test for the energetic material $BKNO_3$ and reconsidered the meaning of the thermal accelerated aging.

Influencing Factors on Successful Aging of Middle and Old Aged Men (중·노년층 남성의 성공적 노화 영향요인)

  • Hong, Seung-Jung;Youn, Mee-Kyung;Lee, Se-Won;Ahn, Hea-Kyung;You, Si-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.7
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    • pp.3275-3283
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    • 2013
  • Purpose: This study is to verify and analyze the influencing factors of successful aging with social support, self-efficacy, community environment and subjective health status on middle and old aged men. Methods: The survey was performed to the men between the ages of 50 and 79 in Seoul and Kyunggi province, Korea. 144 questionnaires were collected and analyzed by SPSS 18.0 program. Stepwise multiple regression was used to identify significant predictors of successful aging. Results: The most influencing factor for successful aging was social support, the second was self-efficacy, the third and the fourth was community environment and subjective health status. This regression model explained 56.7% of the variance in successful aging. Conclusion: The result shows that these variables should be considered in intervention and program of successful aging for middle and old aged men. It can be an important consideration in enhancing promoting care and welfare for the successful aging.

Influence of Electrical Aging on Space Charge Dynamics of Oil-Impregnated Paper Insulation under AC-DC Combined Voltages

  • Wang, Yan;Li, Jian;Wu, Sicheng;Sun, Peng
    • Journal of Electrical Engineering and Technology
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    • v.8 no.6
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    • pp.1512-1519
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    • 2013
  • Oil-impregnated paper is a major type of insulation used in oil-filled converter transformers for both traditional and new energy systems. This paper presents and analyzes the results of the experiment conducted on the electrical aging of oil-impregnated paper under AC-DC combined voltages using the pulsed electro-acoustic (PEA) technique. The formation and dynamics of space charge affected the performance of insulation material. The electrical aged oil-paper insulation was obtained through electrical aged experiments under the voltages. Based on the PEA technique, measurements were carried out when the oil-paper insulation system was subjected to different stressing and aging times. The space charge dynamics in the bulk of the oil-paper insulation system with different aging times were measured and analyzed. Characteristic parameters such as the total charge injection amount, the total charges of fast moving and slow moving, and the distortion factor of electric field were calculated and discussed. Results show that the longer electrical aging time, the more charges trapped in the bulk of aging sample. It leads to larger distortion factor of electric field in the bulk of aging samples and accelerate degradation of oil-paper insulation under AC-DC combined voltages.

L-histidine and L-carnosine exert anti-brain aging effects in D-galactose-induced aged neuronal cells

  • Kim, Yerin;Kim, Yuri
    • Nutrition Research and Practice
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    • v.14 no.3
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    • pp.188-202
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    • 2020
  • BACKGROUND/OBJECTIVES: Brain aging is a major risk factor for severe neurodegenerative diseases. Conversely, L-histidine and L-carnosine are known to exhibit neuroprotective effects. The aim of this study was to examine the potential for L-histidine, L-carnosine, and their combination to mediate anti-brain aging effects in neuronal cells subjected to D-galactose-induced aging. MATERIALS/METHODS: The neuroprotective potential of L-histidine, L-carnosine, and their combination was examined in a retinoic acid-induced neuronal differentiated SH-SY5Y cell line exposed to D-galactose (200 mM) for 48 h. Neuronal cell proliferation, differentiation, and expression of anti-oxidant enzymes and apoptosis markers were subsequently evaluated. RESULTS: Treatment with L-histidine (1 mM), L-carnosine (10 mM), or both for 48 h efficiently improved the proliferation, neurogenesis, and senescence of D-galactose-treated SH-SY5Y cells. In addition, protein expression levels of both neuronal markers (β tubulin-III and neurofilament heavy protein) and anti-oxidant enzymes, glutathione peroxidase-1 and superoxide dismutase-1 were up-regulated. Conversely, protein expression levels of amyloid β (1-42) and cleaved caspase-3 were down-regulated. Levels of mRNA for the pro-inflammatory cytokines, interleukin (IL)-8, IL-1β, and tumor necrosis factor-α were also down-regulated. CONCLUSIONS: To the best of our knowledge, we provide the first evidence that L-histidine, L-carnosine, and their combination mediate anti-aging effects in a neuronal cell line subjected to D-galactose-induced aging. These results suggest the potential benefits of L-histidine and L-carnosine as anti-brain aging agents and they support further research of these amino acid molecules.